Conversion from cyclosporine a to azathioprine treatment improves LDL oxidation in kidney transplant recipients

Kidney International

Volumn 51, Issue 5, 1997, Pages 1608-1612

  Van Den Dorpel, M A ^a   Ghanem, H ^a   Rischen Vos, J ^a   Man In'T Veld, A J ^a   Jansen, H ^a   Weimar, W ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A;

ADULT; AGED; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GRAFT SURVIVAL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY BLOOD FLOW; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0030944042     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1997.221     Document Type: Article

References (43)

1. European Multicentre Trial Group Cyclosporin in cadaveric renal transplantation 5-year follow-up of a multicentre trial Lancet ii 1987 506 509
2. B.L. Kasiske K.L. Tortorice K.L. Heim-Duthoy W.M. Awni K.V. Rao The adverse impact of cyclosporin on serum lipids in renal transplant patients Am J Kidney Dis 17 1991 700 707
3. D.J. Versluis G.J. Wenting W. Weimar Alterations in lipid and carbohydrate metabolism attributable to cyclosporine A in renal transplant recipients Br Med J 292 1986 272 (letter)
4. A.E.G. Raine R. Carter J.I. Mann P.J. Morris Adverse effect of cyclosporin on plasma cholesterol in renal transplant recipients Nephrol Dial Transplant 3 1988 458 463
5. J.J. Curtis Hypertension and kidney transplantation Am J Kidney Dis 7 1986 181 196
6. J.R. Chapman R. Marcen M. Ariaz A.E.G. Raine M.S. Dunnill P.J. Morris Hypertension after renal transplantation: A comparison of cyclosporin and conventional immunosuppression Transplantation 43 1987 860 864
7. W.E. Braun Long-term complications of renal transplantation Kidney Int 37 1990 1363 1378
8. C.M. Ballantyne E.J. Podet W.P. Patsch Y. Harati V. Appel A.M. Gotto J.B. Young Effects of cyclosporin therapy on plasma lipoprotein levels JAMA 262 1989 53 56
9. A.T. Webb D.A. Reaveley M. O'Donnell B. O'Connor A. Seed E.A. Brown Does cyclosporin increase lipoprotein(a) concentrations in renal transplant patients Lancet 341 1993 268 270
10. G. Inselmann A. Barth R. Engemann H.T. Heidemann Cyclosporin B-induced lipid peroxidation in human liver microsomes and its influence on cytochrome P-450 Eur J Clin Invest 21 1991 461 465
11. D.C. Apanay J.F. Neylan M.S. Ragab D.S. Sgoutas Cyclosporine increases the oxidizability of low-density lipoproteins in renal transplant recipients Transplantation 58 1994 663 669
12. H. Ghanem M.A. van den Dorpel W. Weimar A.J. Man in't Veld M.H. El-Kannishy H. Jansen Increased low density lipoprotein oxidation in stable kidney transplant recipients Kidney Int 49 1996 488 493
13. J.E. Taylor N. Scott A. Hill A. Bridges I.S. Henderson W.K. Stewart J.J.F. Belch Oxygen free radicals and platelet and granulocyte aggregability in renal transplant patients Transplantation 55 1990 500 530
14. D. Steinberg S. Parthasarathy T.E. Carew J.C. Khoo J.L. Witztum Beyond cholesterol: Modifications of LDL that increase its atherogenicity N Engl J Med 320 1989 916 924
15. W. Palinski S. Ylä-Herttuala M.E. Rosenfeld S.W. Butler S.A. Socher S. Parthasarathy L.K. Curtiss J.L. Witztum Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein Arteriosclerosis 10 1990 325 335
16. J. Galle I. Schenck P. Schollmeyer C. Wanner Cyclosporine and oxidized lipoproteins affect vascular reactivity: Influence of the endothelium Hypertension 21 1993 315 321
17. X. Yang B. Cai R.R. Sciacca P.J. Cannon Inhibition of inducible nitric oxide synthase in macrophges by oxidized low-density lipoproteins Circ Res 74 1994 318 328
18. F.C. Tanner G. Noll C.M. Boulanger T.F. Lüscher Oxidized low density lipoproteins inhibit relaxations of porcine coronary arteries; role of scavenger receptor and endothelium-derived nitric oxide Circulation 83 1991 2012 2020
19. D.J. Versluis G.J. Wenting F.H.M. Derkx M.A.D.H. Schalekamp J. Jeekel W. Weimar Who should be converted from cyclosporine to conventional immunosuppression in kidney transplantation and why Transplantation 44 1987 387 389
20. R. Zietse P.J. Blankestijn B. Pos A.H.M.M. Balk F.H.M. Derkx W. Weimar M.A.D.H. Schalekamp Optimising glomerular filtration rate and effective renal plasma flow measurements using a simple pharmacokinetic model Clin Nephrol 43 1995 26 34
21. H.A. Kleinveld H.L.M. Hak-Lemmers A.F.H. Stalenhoef P.N.M. Demacker Improved measurement of low-density lipoprotein susceptibility to copper-induced oxidation: Application of a short procedure for isolating low-density lipoprotein Clin Chem 38 1992 2066 2072
22. T.G. Redgrave D.C.K. Roberts E. West Separation of plasma lipoproteins by density gradient ultracentrifugation Anal Biochem 65 1975 42 49
23. M. Burstein H.R. Scholnick R. Morfen Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions J Lipid Res 11 1970 583 595
24. W.T. Friedewald R.I. Lev D.S. Fredrickson Estimation of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge Clin Chem 18 1972 499 502
25. H. Esterbauer G. Striegl H. Puhl M. Rotheneder Continuous monitoring of in vitro oxidation of human LDL Free Radic Res Commun 6 1989 67 75
26. M.A. Austin J.L. Breslow C.H. Hennekens J.E. Buring W.C. Willett R.M. Krauss Low density lipoprotein subclass patterns and the risk of myocardial infarction JAMA 260 1988 1917 1921
27. H. Jansen W. Hop A. van Tol A.V.G. Bruschke J.C. Birkenhager Hepatic lipase and lipoprotein lipase are not major determinants of low density lipoprotein subclass pattern in human subjects with coronary heart disease Atherosclerosis 107 1994 45 54
28. J. Coresh P.O. Kwiterovich H.H. Smith P.S. Bachorik Association of plasma triglyceride concentration and LDL particle diameter, density, and chemical composition with premature coronary artery disease in men and women J Lipid Res 34 1993 1687 1697
29. H. Jansen H. Ghanem H.S.A.M. Kuypers J.C. Birkenhäger Autoantibodies against malondialdehyde-modified LDL are elevated in subjects with an LDL subclass B pattern Atherosclerosis 115 1995 225 262
30. W. Palinski S. Ylä-Herttuala M.E. Rosenfeld S.W. Butler S.A. Socher S. Parthasarathy L.K. Curtiss J.L. Witztum Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein Arteriosclerosis 10 1990 325 335
31. R. Moore D. Thomas E. Morgan D. Wheeler P. Griffin J. Salaman A. Rees Abnormal lipid and lipoprotein profiles following renal transplantation Transplant Proc 25 1993 1060 1061
32. A.M. Fogelman I. Shechter J. Saeger M. Hokom J.S. Child P.A. Edwards Malondialdhyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages Proc Natl Acad Sci USA 77 1980 2214 2218
33. J.A. Berliner M. Territo A. Sevanian S. Ramin J.A. Kim B. Ranshad M. Esterson A.M. Fogelman Minimally modified low density lipoprotein stimulates monocyte endothelial interactions J Clin Invest 85 1990 1260 1266
34. D.W. Morel J.R. Hessler G.M. Chisolm Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipids J Lipid Res 24 1983 1070 1076
35. J. de Graaf H.L. Hak-Lemmers M.C. Hectors P.N. Demacker J.C. Hendriks A.F.H. Stalenhoef Enhanced susceptibility to in vitro oxidation of the dense low density lipoprotein subfraction in healthy subjects Arteriosclerosis Thromb 11 1991 298 306
36. A. Chait R.L. Brazg S. Washington D.L. Tribble Susceptibility of small, dense, low density lipoproteins to oxidative modification in subjects with the atherogenic lipoprotein phenotype pattern B Am J Med 94 1993 350 356
37. Y. Chancerelle M. de Lorgeril R. Viret B. Ciron G. Dureau S. Renaud J.-F. Kergonou Increased lipid peroxidation in cyclosporine-treated heart transplant recipients Am J Cardiol 68 1991 813 816
38. A. Chait Methods for assessing lipid and lipoprotein oxidation Curr Opin Lipid 3 1992 389 394
39. M.A. Austin J.A. Breslow C.H. Hennekens J.E. Buring W.C. Willett R.M. Krauss Low density lipoprotein subclass patterns and the risk of myocardial infarction JAMA 260 1988 1917 1921
40. D.J. Versluis W.E.P. Beyer N. Masurel G.J. Wenting W. Weimar Impairment of the immune response to influenza vaccination in renal transplant recipients by cyclosporine but not azathioprine Transplantation 42 1986 376 379
41. C. Wang A.K. Salahudeen Lipid peroxidation accompanies cyclosporine nephrotoxicity: Effects of vitamin E Kidney Int 47 1995 927 934
42. C.M. Stein A.W. Longmire T.A. Minton L.J. Roberts II T. Pincus J.D. Morrow Cyclosporine-induced alterations in renal function are not associated with lipid peroxidation Transplantation 58 1994 386 388
43. E. Maggi R. Bellazzi A. Gazo M. Seccia G. Bellamo Autoantibodies against oxidatively-modified LDL in uremic patients undergoing dialysis Kidney Int 46 1994 869 876