Experimental evaluation of protective activity of Echinacea pallida against cisplatin toxicity

Phytotherapy Research

Volumn 11, Issue 3, 1997, Pages 263-265

  Mustea, I ^a   Postescu, I D ^a   Tamas, M ^b   Rasnita, T D ^a  

^a THE ONCOLOGY INSTITUTE PROF DR ION CHIRICUTA   (Romania)

^b IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

Cisplatin; E. pallida; Nephrotoxicity

Indexed keywords

ALCOHOL; CISPLATIN; ECHINACEA PALLIDA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY HOMOGENATE; LD 50; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; ORAL DRUG ADMINISTRATION; OXYGEN CONSUMPTION; PROTECTION; WEIGHT REDUCTION;

ANIMALIA; ECHINACEA PALLIDA;

EID: 0030943229     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1099-1573(199705)11:3<263::aid-ptr77>3.3.co;2-s     Document Type: Article

References (7)

1. Bauer, R., and Wagner, H. (1990). In, Echinacea-Handbuch fur Artzte, Apotheker und Naturwissenschaftler, Wissenchaft Verl. mbH, Stuttgart, pp. 25-29, 83.
2. Lueting, B., Steinmuller, C., Giford, G. E., Wagner, H., and Lohmann-Mattes, M. L. (1989). Macrophage activation by the polysaccharide arabinogalactan isolated from plant cell cultures of Echinacea purpurea. J. Natl Cancer Inst. 81, 669-675.
3. Muntean, L., Salontai, A. L., and Botez, C. (1991). Biological studies on Echinacea pallida Nutt and Echinacea purpurea (L) Moench. Herba Rom. 10, 41-50.
4. Pinzani, V., Bresolle, F., Haug, I. J., Galtier, M., Blayac, J., and Balmes, P. (1994). Cisplatin-induced renal toxicity and toxicity-modulating strategies: a review. Cancer Chemother. Pharmacol. 35, 1-9.
5. Singh, G. (1989). A possible cellular mechanism of cisplatin induced nephrotoxicity. Toxicology 58, 71-80.
6. Tamas, M., Rosca, M., and Pacurar, P. (1991). The isolation and analysis of immunologically active polysaccharides from Echinacea augustifolia DC. St. Cercet. Biochim. 34, 49-52.
7. Wagner, H., Proksch, A., Riess-Maurer, I. et al. (1985). Immunostimulierend wirkende Polysaccharide (Heteroglykane) aus hoheren Pflanzen. Arzeimitel Forsch. (Drug. Res.) 35, 1069-1075.