Analysis of the content of the diterpenes cafestol and kahweol in coffee brews

Food and Chemical Toxicology

Volumn 35, Issue 6, 1997, Pages 547-554

  Gross, G ^a   Jaccaud, E ^a   Huggett, A C ^a  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DITERPENE;

ARTICLE; COFFEE; FOOD ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

CHOLESTEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COFFEE; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; FOOD ANALYSIS; HUMANS; SENSITIVITY AND SPECIFICITY;

EID: 0030943042     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(96)00123-8     Document Type: Article

References (34)

1. Aeschbacher H. U. and Jaccaud E. (1990) Inhibition by coffee of nitrosourea mediated DNA damage in mice. Food and Chemical Toxicology 28, 633-637.
2. Ahola I., Jauhiainen M. and Aro A. (1991) The hypercholesterolaemic factor of boiled coffee is retained by a paper filter. Journal of Internal Medicine 230, 293-297.
3. Aro A., Tuomilehto J., Kostiainen E., Uusitalo U. and Pietinen P. (1987) Boiled coffee increases serum low density lipoprotein concentration. Metabolism 36, 1027-1030.
4. Bak A. A. A. and Grobbee D. E. (1989) The effect on serum cholesterol levels of coffee brewed by filtering or boiling. New England Journal of Medicine 321, 1432-1437.
5. Baron J. A., de Verdier M. G. and Ekbom A. (1994) Coffee, tea, tobacco, and cancer of the large bowel. Cancer Epidemiology, Biomarkers and Prevention 3, 565-570.
6. Bertholet R. (1987) Preparation of cafestol. United States Patent 4,692,534.
7. Burr M. L., Gallacher J. E., Butland B. K., Bolton C. H. and Downs L. G. (1989) Coffee, blood pressure and plasma lipids: a randomized controlled trial. European Journal of Clinical Nutrition 43, 477-483.
8. Di Simplicio P., Jensson H. and Mannervik B. (1989) Effects of inducers of drug metabolism on basic hepatic forms of mouse glutathione transferase. Biochemical Journal 263, 679-685.
9. Huggett A. C., Marchesini M. and Perrin I. (1993) Effects of coffee oil on plasma cholesterol in the rat. In 15th International Scientific Colloquium on Coffee. pp. 497-503. Association Scientifique International du Café, Paris.
10. Huggett A. C. and Schilter B. (1995) The chemoprotective effects of cafestol and kahweol: effects on xenobiotic metabolising enzymes. Journal of Cellular Biochemistry 19A, 190.
11. IARC (1991) IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans. Vol. 51. Coffee, Tea, Maté, Methylxanthines and Methylglyoxal. pp. 41-206. International Agency for Research on Cancer, Lyon.
12. Kark J. D., Friedlander Y., Kaufmann N. A. and Stein Y. (1985) Coffee, tea and plasma cholesterol: the Jerusalem Lipid Research Clinic prevalence study. British Medical Journal 291, 699-704.
13. Lam L. T. K., Sparnins V. L. and Wattenberg L. W. (1982) Isolation and identification of kahweol palmitate and cafestol palmitate as active constituents of green coffee beans that enhance glutathione S-transferase activity in the mouse. Cancer Research 42, 1193-1198.
14. Lercker G., Frega N., Bocci F. and Rodriguez-Estrada M. T. (1995) High resolution gas chromatographic determination of diterpenic alcohols and sterols in coffee lipids. Chromatographia 41, 29-33.
15. Mensink R. P., Lebbink W. J., Lobbezoo I. E., Weusten-Van der Wouw M. P. M. E., Zock P. L. and Katan M. B. (1995) Diterpene composition of oils from Arabica and Robusta coffee beans and their effects on serum lipids in man. Journal of Internal Medicine 237, 543-550.
16. Mensink R. P., Zock P. L., Katan M. B. and Beynen A. C. (1992) Boiled coffee does not increase serum cholesterol in gerbils and hamsters. Zeitschrift für Ernahrungswissenschaft 31, 82-85.
17. Miller E. G., Formby W. A., Rivera-Hidalgo F. and Wright J. M. (1988) Inhibition of hamster buccal pouch carcinogenesis by green coffee beans. Oral Surgery 65, 745-749.
18. Miller E. G., Gonzales-Sanders A. P., Couvillon A. M., Binnie W. H., Sunahara G. I. and Bertholet R. (1993) Inhibition of oral carcinogenesis by roasted beans and roasted coffee bean fractions. In 15th International Scientific Colloquium on Coffee. pp. 420-425. Association Scientifique International du Café, Paris.
19. Miller E. G., McWhorter K., Rivera-Hidalgo F., Wright J. M., Hirsbrunner P. and Sunahara G. I. (1991) Kahweol and cafestol: inhibitors of hamster buccal pouch carcinogenesis. Nutrition and Cancer 15, 41-46.
20. Pietinen P., Aro A., Tuomilehto J., Uusitalo U. and Korhonen H. (1990) Consumption of boiled coffee is correlated with serum cholesterol in Finland. International Journal of Epidemiology 19, 586-590.
21. Ratnayake W. M. N., Hollywood R., O'Grady E. and Stavric B. (1993) Lipid content and composition of coffee brews prepared by different methods. Food and Chemical Toxicology 31, 263-269.
22. Ratnayake W. M. N., Pelletier G., Hollywood R., Malcolm S. and Stavric B. (1995) Investigation of the coffee lipids on serum cholesterol in hamsters. Food and Chemical Toxicology 33, 195-201.
23. Sanders T. A. B. and Sandaradura S. (1992) The cholesterol-raising effect of coffee in the Syrian hamster. British Journal of Nutrition 68, 431-434.
24. Sanguigni V., Gallu M. P., Ruffini M. P. and Strano A. (1995) Effects of coffee on serum cholesterol and lipoproteins: the Italian brewing method. European Journal of Epidemiology 11, 75-78.
25. Stensvold I., Tverdal A. and Foss O. P. (1989) The effect of coffee on blood lipids and blood pressure. Results from a Norwegian cross-sectional study, men and women, 40-42 years. Journal of Clinical Epidemiology 42, 877-884.
26. Thelle D. S., Arnesen E. and Forde O. H. (1983) The Tromso heart study: does coffee raise serum cholesterol? New England Journal of Medicine 308, 1454-1457.
27. Thelle D. S., Heyden S. and Fodor J. G. (1987) Coffee and cholesterol in epidemiological and experimental studies. Atherosclerosis 67, 97-103.
28. Thelle D.S. and Van der Stegen G. (1990) In Coffee and Coronary Heart Disease, Special Emphasis on the Coffee-Blood Lipids Relationship. Edited by D.S. Thelle and G. Van der Stegen. pp. 9-15. Gotab, Stockholm.
29. Urgert R., Schulz A. G. M. and Katan M. B. (1995a) Effects of cafestol and kahweol from coffee grounds on serum lipids and serum liver enzymes in humans. American Journal of Clinical Nutrition 61, 149-154.
30. Urgert R., van der Weg G., Kosmeijer-Schuil T. G., van de Bovenkamp P., Hovenier R. and Katan M. B. (1995b) Levels of the cholesterol-elevating diterpenes cafestol and kahweol in various coffee brews. Journal of Agricultural and Food Chemistry 43, 2167-2172.
31. Van Dusseldorp M., Katan M. B., Van Vliet T., Demacker P. N. M. and Stalenhoef A. F. H. (1991) Cholesterol-raising factor from boiled coffee does not pass a paper filter. Arteriosclerosis and Thrombosis 11, 586-593.
32. Wattenberg L. W. (1983) Inhibition of neoplasia by minor dietary constituents. Cancer Research 43, 2448-2453.
33. Wattenberg L. W., Hanley A. B., Barany G., Sparnins V. L., Lam L. K. T. and Fenwick G. R. (1985) Inhibition of carcinogenesis by some minor dietary constituents. International Symposium. Princess Takamatsu Cancer Research Fund 16, 193-203.
34. Weusten-Van der Wouw M. P. M. E., Katan M. B., Viani R., Huggett A. C., Liardon R., Lund-Larsen P. G., Thelle D. S., Ahola I., Aro A., Meyboom S. and Beynen A. C. (1994) Identity of the cholesterol-raising factor from boiled coffee and its effect on liver function enzymes. Journal of Lipid Research 35, 721-733.