Stereoselective metabolism of famprofazone in humans: N-dealkylation and β and p-hydroxylation

Chirality

Volumn 9, Issue 1, 1997, Pages 52-58

  Shin, H O Sang ^a  

^a KWWI   (South Korea)

Author keywords

hydroxylation; famprofazone; N dealkylation; p hydroxylation; stereoselective metabolism

Indexed keywords

4 HYDROXYPHENYLPROPANOLAMINE; AMPHETAMINE; ANALGESIC AGENT; DRUG METABOLITE; EPHEDRINE; FAMPROFAZONE; HYDROXYAMPHETAMINE; METHAMPHETAMINE; NOREPHEDRINE; NORPSEUDOEPHEDRINE; PHOLEDRINE; PSEUDOEPHEDRINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CAPILLARY GAS CHROMATOGRAPHY; CHIRALITY; DEALKYLATION; DERIVATIZATION; DIASTEREOISOMER; DRUG HYDROXYLATION; DRUG METABOLISM; ENANTIOMER; HUMAN; HUMAN EXPERIMENT; ION MONITORING; MALE; MASS SPECTROMETRY; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RACEMIC MIXTURE; STEREOCHEMISTRY; TABLET;

ADMINISTRATION, ORAL; ADULT; ANALGESICS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALIBRATION; CHROMATOGRAPHY, GAS; DEALKYLATION; HUMANS; HYDROXYLATION; MALE; METHAMPHETAMINE; OXIDATION-REDUCTION; PYRAZOLES; PYRAZOLONES; STEREOISOMERISM;

EID: 0030942779     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(1997)9:1<52::AID-CHIR10>3.0.CO;2-P     Document Type: Article

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