Inhibition of the mutagenicity of 2-nitrofluorene, 3-nitrofluoranthene and 1-nitropyrene by vitamins, porphyrins and related compounds, and vegetable and fruit juices and solvent extracts

Food and Chemical Toxicology

Volumn 35, Issue 3-4, 1997, Pages 373-378

  Tang, X ^a   Edenharder, R ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Antimutagenicity; Nitroarines; Salmonella reversion assay

Indexed keywords

1 NITROPYRENE; 2 NITROFLUORENE; ACETOMENAPHTHONE; ALPHA TOCOPHEROL; ANTIMUTAGENIC AGENT; AROMATIC NITRO COMPOUND; ASCORBIC ACID; BETA CAROTENE; BILIRUBIN; BILIVERDIN; CHLOROPHYLL; CYANOCOBALAMIN; FOLIC ACID; HEMIN; NICOTINAMIDE; NICOTINIC ACID; PANTOTHENIC ACID; PORPHYRIN DERIVATIVE; PYRIDOXAL; PYRIDOXAMINE; RETINAL; RETINOIC ACID; RETINOL; RETINOL PALMITATE; RIBOFLAVIN; THIAMINE; VITAMIN; VITAMIN B GROUP; VITAMIN K GROUP;

ARTICLE; CONTROLLED STUDY; FRUIT JUICE; MUTAGENICITY; NONHUMAN; SALMONELLA TYPHIMURIUM; VEGETABLE;

ACTINIDIA CHINENSIS; ANANAS COMOSUS; APIUM GRAVEOLENS RAPACEUM; BRASSICA OLERACEA VAR. BOTRYTIS; CAPSICUM; CICHORIUM INTYBUS; DAUCUS CAROTA; FOENICULUM VULGARE; SALMONELLA; SALMONELLA TYPHIMURIUM; SOLANUM MELONGENA; SPINACIA OLERACEA; TYPHIMURIUM; VITACEAE;

EID: 0030942668     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(97)00126-9     Document Type: Article

References (26)

1. Arimoto S., Negishi T. and Hayatsu H. (1980) Inhibitory effect of hemin on the mutagenic activities of carcinogens. Cancer Letters 11, 29-33.
2. 1: in vitro effects of vitamins. Mutation Research 188, 121-128.
3. Block G., Patterson B. and Subar A. (1992) Fruit, vegetables and cancer prevention: a review of the epidemiological evidence. Nutrition and Cancer 18, 1-29.
4. Brockman H. E., Stack H. F. and Waters M. D. (1992) Antimutagenic profiles of some natural substances. Mutation Research 267, 157-172.
5. Busk L. and Ahlborg U. G. (1982) Retinoids as inhibitors of ortho-aminoazotoluene-induced mutagenesis in the Salmonella/liver microsome test. Mutation Research 104, 225-231.
6. Busk L., Sjöström B. and Ahlborg U. G. (1984) Effects of vitamin A on cyclophosphamide mutagenicity in vitro (Ames test) and in vivo (mouse micronucleus test). Food and Chemical Toxicology 22, 725-730.
7. De Flora S., Rosenkranz H. S. and Klopman G. (1994) Structural basis of antimutagenicity of chemicals towards 4-nitroquinoline-1-oxide in Salmonella typhimurium. Mutagenesis 9, 39-45.
8. Edenharder R. and Tang X. (1997) Inhibition of the mutagenicity of 2-nitrofluorene, 3-nitrofluoranthene and 1-nitropyrene by flavonoids, coumarins, quinones and other phenolic compounds. Food and Chemical Toxicology 35, 357-372.
9. Edenharder R. and Worf-Wandelburg A. (1990) Einfluß von Vitaminen auf die Mutagenität von IQ, MeIQ, MeIQx, Trp-P-2 and Glu-P-1. Zentralblatt Hygiene 191, 21.
10. Edenharder R., Kurz P., John K., Burgard S. and Seeger K. (1994) In vitro effect of vegetable and fruit juices on the mutagenicity of 2-amino-3-methyl-imidazo[4,5-f]-quinoline, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline. Food and Chemical Toxicology 32, 443-459.
11. Edenharder R., Leopold Ch. and Kries M. (1995) Modifying actions of solvent extracts from fruit and vegetable residues on 2-amino-3-methylimidazo[4,5-f]-quinoline (IQ) and 2-amino-3,8-dimethylimidazo[4,5-f]-quinoxaline (MeIQx) induced mutagenesis in Salmonella typhimurium. Mutation Research 341, 303-318.
12. Espinosa-Aguirre J. J., Reyes R. E., Rubio J., Ostrosky-Wegman P. and Martinez G. (1993) Mutagenic activity of urban air samples and its modulation by chili extracts. Mutation Research 303, 55-61.
13. Hartman E. and Shankel D. M. (1990) Antimutagens and anticarcinogens. A survey of putative interceptor molecules. Environmental and Molecular Mutagenesis 15, 145-182.
14. Hayatsu H., Arimoto S. and Negishi T. (1988) Dietary inhibitors of mutagenesis and carcinogenesis. Mutation Research 202, 429-446.
15. Higashimoto M., Purintrapiban J., Kataoka K., Kinouchi T., Vinitketkumnuen U., Akimoto S., Matsumoto H. and Ohnishi Y. (1993) Mutagenicity and antimutagenicity of extracts of three spices and a medicinal plant in Thailand. Mutation Research 303, 135-142.
16. Huang M.-T., Wood A. W., Newmark H. L., Sayer J. M., Yagi H., Jerina D. M. and Conney A. H. (1983) Inhibition of the mutagenicity of bay region diol epoxides of polycyclic aromatic hydrocarbons by plant flavonoids. Carcinogenesis 4, 1631-1637.
17. Ioannides C., Ayrton A. D., Keele A., Lewis D. F. V., Flatt P. R. and Walker (1990) Mechanism of the in vitro antimutagenic action of retinol. Mutagenesis 5, 257-262.
18. Israels L. G., Walls G. A., Ollmann D. J., Friesen L. and Israels E. D. (1983) Vitamin K as regulator of benzo[a]pyrene metabolism, mutagenesis, and carcinogenesis. Journal of Clinical Investigation 71, 1130-1140.
19. Kada T., Morita K. and Inoue T. (1978) Anti-mutagenic action of vegetable factor(s) on the mutagenic principle of tryptophan pyrolysate. Mutation Research 53, 351-353.
20. Lai C. N., Butler M. A. and Matney T. S. (1980) Antimutagenic activities of common vegetables and their chlorophyll content. Mutation Research 77, 245-250.
21. Morita K., Masako H. and Kada T. (1978) Studies on natural desmutagens: screening for vegetable and fruit factors active in inactivation of mutagenic pyrolysis products from amino acids. Agricultural and Biological Chemistry 42, 1235-1238.
22. Sarkar D., Sharma A. and Talukder G. (1994) Chlorophyll and chlorophyllin as modifiers of genotoxic effects. Mutation Research 318, 239-247.
23. Shetty T. K., Francis A. R. and Bhattacharya R. K. (1988) Modifying role of vitamins on the mutagenic action of N-methyl-N′-nitro-N-nitrosoguanidine. Carcinogenesis 9, 1513-1515.
24. Souci S.W., Fachmann W. and Kraut H. (1989) Food Composition and Nutrition Tables 1989/90. 4th Ed. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart.
25. Steinmetz K. A. and Potter J. D. (1991) Vegetables, fruit and cancer, I. Epidemiology (Review). Cancer, Causes and Control 5, 325-357.
26. Terwel L. and van der Hoeven J. C. M. (1985) Antimutagenic activity of some naturally occurring compounds towards cigarette-smoke condensate and benzo[a]pyrene in the Salmonella/microsome assay. Mutation Research 152, 1-4.