Biology of EWS/FLI and related fusion genes in Ewing's sarcoma and primitive neuroectodermal tumor

Current Topics in Microbiology and Immunology

Volumn 220, Issue , 1997, Pages 143-150

  May, W A ^a   Denny, C T ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

CHROMOSOME 22; CHROMOSOME TRANSLOCATION; CYTOGENETICS; EWING SARCOMA; HUMAN; NEUROECTODERM TUMOR; ONCOGENE; PRIORITY JOURNAL; REVIEW;

EID: 0030941517     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-60479-9_9     Document Type: Review

References (7)

1. Bailly RA, Bosselut R, Zucman J, Cormier F, Delattre O, Roussel M, Thomas G and Ghysdael J (1994) DNA-binding and transcriptional activation properties of the fusion protein resulting from the t(11;22) translocation in Ewing sarcoma. Mol Cell Biol 14: 3230-3241
2. Ben-David YEB, Giddens EB, Letwin K and Bernstein A (1991) Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ETS gene family FLi-1, closely linked to c-ETS-1. Genes Dev 5: 908-918
3. Braun BS, Freiden R, Lessnick SL, May WA and Denny CT (1996) Identification of target genes to the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis. Mol Cell Biol (in press)
4. Cavazzana AO, Ninfo V, Roberts J and Triche TJ (1992) Peripheral neuroepithelioma: a light microscopic, immunocytochemical, and ultrastructural study. Mod Pathol 5: 71-78
5. Dalton S and Treisman R (1992) Characterization of SAP-1, a protein recruited serum response factor to the c-fos serum response element. Cell 68: 597-612
6. Whang-Peng J, Triche TJ, Knutsen T, Miser J, Kao-Shan S, Tsai S and Israel MA (1986) Cytogenetic characterization of selected small round cell tumors of childhood. Cancer Gene Cytogene 21: 185-208
7. Zhang L, Lemarchandel V, Romeo PH, Ben-David Y, Greer P and Bernstein A (1993) The Fli-1 proto-oncogene, involved in erythroleukemia and sarcoma, encodes a transcriptional activator with DNA-binding specificities distinct from other ETS family members. Oncogene 8: 1621-1630