Colonic mucin discharge by a cholinergic agonist, prostaglandins, and peptide YY in the isolated vascularly perfused rat colon

Digestion

Volumn 58, Issue 2, 1997, Pages 168-175

  Plaisancié, Pascale ^a,b   Bosshard, Arlette ^a   Meslin, Jean Claude ^b   Cuber, Jean Claude ^b  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b CEMAGREF   (France)

Author keywords

Bethanechol; Isolated; Mucus discharge; Peptide YY; Prostaglandins; Vascularly perfused rat colon

Indexed keywords

16,16 DIMETHYLPROSTAGLANDIN E2; BETHANECHOL; CHOLINERGIC RECEPTOR STIMULATING AGENT; MUCIN; PEPTIDE YY; PROSTAGLANDIN; PROSTAGLANDIN F2 ALPHA;

ANIMAL EXPERIMENT; ARTICLE; CATTLE; CELL COUNT; COLON; CONCENTRATION RESPONSE; CONTROLLED STUDY; ERYTHROCYTE; GOBLET CELL; INTESTINE CRYPT; INTRAARTERIAL DRUG ADMINISTRATION; MALE; MUCUS; NONHUMAN; PERFUSION; PRIORITY JOURNAL; RAT; SECRETION; SUPERIOR MESENTERIC ARTERY;

ANIMALS; BETHANECHOL; CELL MEMBRANE; CHOLINERGIC AGONISTS; COLON; DOGS; INTESTINAL MUCOSA; MALE; MUCINS; MUCUS; PEPTIDE YY; PEPTIDES; PROSTAGLANDINS; RATS; RATS, WISTAR;

EID: 0030941442     PISSN: 00122823     EISSN: 14219867     Source Type: Journal    
DOI: 10.1159/000201440     Document Type: Article

References (34)

1. Specian RD, Oliver MG: Functional biology of intestinal goblet cells. Am J Physiol 1991:260: C183-C193.
2. Neutra MR, Forstner JF: Gastrointestinal mucus: Synthesis, secretion, and function; in Johnson LR (ed): Physiology of the Gastrointestinal Tract, ed 2. New York. Raven Press. 1987, vol 2. chap 34, pp 975-1001.
3. Forstner JF, Forstner GG: Gastrointestinal mucus: in Johnson LR (ed): Physiology of the Gastrointestinal Tract, ed 3. New York. Raven Press. 1994. vol 2, chap 33. pp 1255-1283.
4. Forstner G: Signal transduction, packaging and secretion of mucins. Annu Rev Physiol 1995: 57:585-605.
5. Sepcian RD, Neutra MR: Regulation of intestinal goblet cell secretion. I. Role of parasympathetic stimulation. Am J Physiol 1952:242: G370-379.
6. Phillips TE: Both crypt and villus intestinal goblet cells secrete mucin in response to cholinergic stimulation. Am J Physiol 1992:262: G327-G33I.
7. Loeschke K, Schmid T, Farack UM: Inhibition by loperamide of mucus secretion in the rat colon in vivo. Eur J Pharmacol 1989; 170:41-46.
8. Phillips TE, Stanley CM, Wilson J: The effect of 16.16-dimethyl prostaglandin E? on proliferation of an intestinal goblet cell line and its synthesis and secretion of mucin glycoproteins. Prostaglandins Leukot Esscnt Fatty Acids 1993:48:423-428.
9. Lundberg JM, Tatemoto K, Terenius L, Hellström PM, Mutt V, Hökhfeli T, Hamberger B: Localization of peptide YY (PYY) in the gastrointestinal endocrine cells and effects on intestinal blood flow and motility. Proc Natl AcadSci USA 1982;79:4471-4475.
10. Adrian TE, Ferri GL, Bacarese-Hamilton AJ, Fuessl HS, Polak JM, Bloom SR: Human distribution and release of a putative new gut hormone. peptide YY. Gastroenterology 1985:89: 1070-1077.
11. Taylor IL: Distribution and release of peptide YY in dog measured by specific radioimmunoassay. Gastroenterology 1985:88:731-737.
12. Greeley GH, Hill FLC, Spannagel A, Thompson JC: Distribution of peptide YY in the gastrointestinal tract of the rat. dog and monkey. Regul Pept 1987:19:365-372.
13. Plaisancie P, Bernard C, Chayvialle JA, Cuber JC: Release of peptide YY by neurotransmil-tcrsand gut hormones in the isolated vascularlv perfused rat colon. Scand J Gastroenterol 1995:30:568-574.
14. Bosshard A, Cherv-Croze S, Cuber JC, Deche-lette MA, Berger F, Chayvialle JA: Immunocy-tochemical study of peptidergic structures in Brunner's glands. Gastroenterology 1989:97: 1382-1388.
15. Altmann GG: Morphological observations on mucus-secreting nongoblet cells in the deep crypts of the rat ascending colon. Am J Anat 1983:167:95-117.
16. Sakata T, Engelhardt WV: Influence of short-chain fatty acids and osmolality on mucin release in the rat colon. Cell Tissue Res 1981:219: 371-377.
17. Specian RD, Neutra MR: Mechanism of a rapid mucus secretion in goblet cells stimulated by acetylcholine. J Cell Biol 1980;85:626-640.
18. Phillips TE, Phillips TH, Neutra MR: Regulation of intestinal goblet cell secretion. III. Isolated intestinal epithelium. Am J Physiol 1984: 247:G674-G681.
19. Roumagnac I, Laboisse CL: A mucus secreting human colonic epithelial cell line responsive to cholinergic stimulation. Biol Cell 1987:61:65-68.
20. Phillips TE, Huet C, Bilbo PR, Podolsky DK, Louvard D, Neutra MR: Human intestinal goblet cells in monolayer culture: Characterization of a mucus-secreting subclone derived from HT29 colonic adenocarcinoma cell line. Gastroenterology 1988;94:1390-1403.
21. McCool DJ, Marcon MA, Forstner JF, Forst-ner GG: The T84 human colonic adenocarcinoma cell line produces mucin in culture and releases it in response to various secretagogues. Biochcm J 1990;267:491-500.
22. Phillips TE, Wilson J: Morphometric analysis of mucous granule depletion and replenishment in rat colon. Dig Dis Sci 1993:38:2299-2304.
23. Phillips TE, Wilson J: Signal transduction pathways mediating mucin secretion from intestinal goblet cells. Dig Dis Sci 1993:38:1046-1054.
24. Scidlcr U, Knafia K, Kownatzki R, Sewing KF: ETeels of endogenous and exogenous prostaglandins on glycoprotein synthesis and secretion in the isolated rabbit gastric mucosa. Gastroenterology 1988;95:945-951.
25. Tatemoto K: Isolation and characterization of peptide YY (PYY), a candidate gut hormone that inhibits pancreatic exocrine secretion. Proc Natl AcadSci USA 1982;79:2514-2518.
26. Pappas TN, Debas HT, Goto Y, Taylor IL: Peptide YY inhibits meal-stimulated pancreatic and gastric secretion. Am J Physiol 1985; 248:G118-G123.
27. Adrian TE, Savage AP, Sagor GR, Allen JM, Bacarese-Hamilton AJ, Tatemoto K, Polak JM, Bloom SR: Effect of peptide YY on gastric, pancreatic, and biliary function in humans. Gastroenterology 1985:89:494-499.
28. Suzuki T, Nakaya M, Itoh Z, Tatemoto K, Mutt V: Inhibition of interdigestive contractile activity in the stomach by peptide YY in Hei-denhain pouch dogs. Gastroenterology 1983; 85:114-121.
29. Pappas TN, Debas HT, Chang AM, Taylor IL: Peptide YY release by fatty acids is sufficient to inhibit gastric emptying in dogs. Gastroenterology 1986:91:1386-1389.
30. Al-Saffar A, Hellstrom PM, Nylander G: Correlation between peptide YY-induced myoelectric activity and transit of small-intestinal contents in rats. Scand J Gastroenterol 1985: 20:577-582.
31. Okuno M, Nakanishi T, Shinomura Y, Kiyohara T, Ishikawa H, Tarui S: Peptide YY enhances NaCI and water absorption in the rat colon in vivo. Experientia 1992;48:47-50.
32. Bilchik AJ, Hines OJ, Adrian TE, McFadden DW, Berger JJ, Zinncr MJ, Ashley SW: Peptide YY is a physiological regulator of water and electrolyte absorption in the canine small bowel in vivo. Gastroenterology 1993:105:1441-1448.
33. Brubaker PL, Drucker DJ, Asa SL, Greenberg GR: Regulation of peptide-YY synthesis and secretion in fetal intestinal cultures. Endocrinology 1991:129:3351-3358.
34. Longo WE, Ballantync GH, Savoca PE, Adrian TE, Bilchik AJ, Modlin IM: Short-chain fatty acid release of peptide-YY in the isolated rabbit distal colon. Scand J Gastroenterol 1991;26: 442-448.