Combined therapy of multidrug-resistant human lung cancer with anti-p- glycoprotein antibody and monocyte chemoattractant protein-1 gene transduction: The possibility of immunological overcoming of multidrug resistance

International Journal of Cancer

Volumn 71, Issue 2, 1997, Pages 170-177

  Nishioka, Yasuhiko ^a   Yano, Seiji ^a   Fujiki, Fujio ^a,b   Mukaida, Naofumi ^b   Matsushima, Kouji ^b   Tsuruo, Takashi ^c   Sone, Saburo ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ARTICLE; CANCER CELL CULTURE; CARCINOGENICITY; CELL GROWTH; CONTROLLED STUDY; EXPRESSION VECTOR; FEMALE; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG CANCER; MONOCYTE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; CARCINOMA, SMALL CELL; CHEMOKINE CCL2; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; HUMANS; KILLER CELLS; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; P-GLYCOPROTEIN; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0030941377     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970410)71:2<170::AID-IJC8>3.0.CO;2-Y     Document Type: Article

References (27)

1. BOTTAZZI, B., WALTER, S., GOVONI, D., COLOTTA, F. and MANTOVANI, A., Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma. J. Immunol., 148, 1280-1285 (1992).
2. DRANOFF, G., JAFFFEE, E., LAZENBY, A., GOLUMBEK, P., LEVITSKY, H., BROSE, K., JACKSON, V., HAMADA, H., PARDOLL, D. and MULLIGAN, R.C., Vaccination with irradiated tumor cells engineered to secrete murine granuloeyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. nat. Acad. Sci. (Wash.), 90, 3539-3543 (1993).
3. ERNST, C.A., ZHANG, Y.J., HANCOCK, P.R., RUTLEDGE, B.J., CORLESS, C.L. and ROLLINS, B.J., Biochemical and biologic characterization of murine monocyte chemoattractant protein-1. J. Immunol., 152, 3541-3549 (1994).
4. FURUTANI, Y., NOMURA, H., NOTAKE, M., OYAMADA, Y., FUKUI, T., YAMADA, M., LARSEN, C.G., OPPENHEIM, J.J. and MATSUSHIMA, K., Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF). Biochem. biophys. Res. Comm., 159, 249-255 (1989).
5. HAMADA, H. and TSURUO, T., Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. Proc. nat. Acad. Sci. (Wash.), 83, 7785-7789 (1986).
6. HAMADA, H. and TSURUO, T., Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug-resistance. J. biol. Chem., 263, 1454-1458 (1988).
7. HAYASHI, H., KAMOHARA, S., NISHIOKA, Y. KANAI, F., MIYAKE, N., FUKUI, Y., SHIBASAKI, F., TAKENAWA, T. and EBINA, Y. Insulin treatment stimulates the tyrosine phosphorylation of the α-type 85-kDa subunit of phosphatidylinositol 3-kinase in vivo. J. biol. Chem., 267, 22575-22580 (1992).
8. HEIKE, Y., SONE, S., YANO, S., SEIMIYA, H., TSURUO, T. and OGURA, T., M-CSF gene transduction in multidrug-resistant human cancer cells to enhance anti-P-glycoprotein antibody-dependent macrophage-mediated cytotoxicity. Int. J. Cancer, 54, 851-857 (1993).
9. HIROSE, K., HAKOZAKI, M., NYUNOYA, Y., KOBAYASHI, Y., MATSUSHITA, K., TAKENOUCHI, T., MIKATA, A., MUKAIDA, N. and MATSUSHIMA, K., Chemokine gene transfection into tumour cells reduced tumorigenicity in nude mice in association with neutrophilic infiltration. Brit. J. Cancer, 72, 708-714 (1995).
10. HOCK, H., DORSCH, M., KUNZENDORF, U., QIN, Z., DIAMANTSTEIN, T. and BLANKENSTEIN, T., Mechanisms of rejection induced by tumor-cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or Interferon γ. Proc. nat. Acad. Sci. (Wash.), 90, 2774-2778 (1993).
11. HOLZMAYER, T.A., HILSENBECK, S., VON HOFF, D.D. and RONINSON, I.B., Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas. J. nat. Cancer Inst., 84, 1486-1491 (1992).
12. IWAHASHI, T., OKOCHI, E., ARIYOSHI, K., WATABE, H., AMANN, E., MORI, S., TSURUO, T. and ONO, K., Specific targeting and killing activities of anti-P-glycoprotein monoclonal antibody MRK16 directed against intrinsically multidrug-resistant human colorectal carcinoma cell lines in the nude mouse model. Cancer Res., 53, 5475-5482 (1993).
13. Ko, Y-C., MUKAIDA, N., PANYUTICH, A., VOITENOK, N.N., MATSUSHIMA, K., KAWAI, T. and KASAHARA, T., A sensitive enzyme-linked immunosorbent assay for human interleukin-8. J. immunol. Meth., 149, 227-235 (1992).
14. LUINI, W., SOZZANI, S., DAMME, J-V. and MANTOVANI, A., Species-specificity of monocyte chemotactic protein-1 and -3. Cytokine, 6, 28-31 (1994).
15. MINATO, K., KANZAWA, F., NISHIO, K., NAKAGAWA, K., FIMIWARA, Y. and SAIJO, N., Characterization of an etoposide-resistant human small-cell lung cancer cell line. Cancer Chemother. Pharmacol., 26, 313-317 (1990).
16. NAKANO, Y., KASAHARA, T., MUKAIDA, N., KO, Y-C., NAKANO, M. and MATSUSHIMA, K., Protection against lethal bacterial infection in mice bymonocyte-chemotactic and -activating factor. Infect. Immun., 62, 377-383 (1994).
17. NISHIOKA, Y., SONE, S., HEIKE, Y. HAMADA, H., ARIYOSHI, K., TSURUO, T. and OGURA, T., Effector cell analysis of human multidrug-resistant cell killing by mouse-human chimeric antibody against P-glycoprotein. Jap. J. Cancer Res., 83, 644-649 (1992).
18. NISHIOKA, Y., SONE, S., ORINO, E., NII, A. and OGURA, T., Down-regulation by interleukin 4 of activation of human alveolar macrophages to the tumoricidal state. Cancer Res., 51, 5526-5531 (1991).
19. NOONAN, K.E., BECK, C., HOLZMAYER, T.A., CHIN, J.E., WUNDER, J.S., ANDRULIS, I.L., GAZDAR, A.F., WILLMAN, C.L., GRIFFITH, B., VON HOFF, D.D. and RONINSON, I.B., Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction. Proc. nat. Acad. Sci. (Wash.), 87, 7160-7164 (1990).
20. ROLLINS, B.J. and SUNDAY, M.E., Suppression of tumor formation in vivo by expression of the JE gene in malignant cells. Mol. cell. Biol., 11, 3125-3131 (1991).
21. ROSENBERG, S.A., The immunotherapy and gene therapy of cancer. J. clin. Oncol., 10, 180-199 (1992).
22. SINGH, R.K., BERRY, K., MATSUSHIMA, K., YASUMOTO, K. and FIDLER, I.J., Synergism between human monocyte chemotactic and activating factor and bacterial products for activation of tumoricidal properties in murine macrophages. J. Immunol., 151, 2786-2793 (1993).
23. SONE, S., INAMURA, N., NII, A. and OGURA, T., Heterogeneity of human lymphokine (IL-2)-activated killer (LAK) precursors and regulation of their LAK induction by blood monocytes. Int. J. Cancer. 42, 428-4341 (1988).
24. TSURUO, T. and FIDLER, I.J., Differences in drug sensitivity among tumor cells from parental tumors, selected variants, and spontaneous metastases. Cancer Res., 41, 3058-3064 (1981).
25. TSURUO, T., HAMADA, H., SATO, S. and HEIKE, Y., Inhibition of multidrug-resistant human tumor growth in athymic mice by anti-P-glycoprotein monoclonal antibodies. Jap. J. Cancer Res., 80, 627-631 (1989).
26. WATANABE, Y., KURIBAYASHI, K., MIYATAKE, S., NISHIHARA, K., NAKAYAMA, E., TANIYAMA, T. and SAKATA, T., Exogenous expression of mouse Interferon γ cDNA in mouse neuroblastoma C1300 cells results in reduced tumorigenicity by augmented anti-tumor immunity. Proc. nat. Acad. Sci. (Wash.), 86, 9456-9460 (1989).
27. YANO, S., SONE, S., NISHIOKA, Y., MUKAIDA, N., MATSUSHIMA, K. and OGURA, T., Differential effects of anti-inflammatory cytokines (IL-4, IL-10 and IL-13) on tumoricidal and chemotactic properties of human monocytes induced by monocyte chemotactic and activating factor (MCAF). J. Leukocyte Biol., 57, 303-309 (1995).