Characterisation of the leukotoxin produced by different strains of Pasteurella haemolytica

Journal of Medical Microbiology

Volumn 46, Issue 4, 1997, Pages 276-284

  Saadati, M ^a   Gibbs, H A ^a   Parton, R ^a   Coote, J G ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LEUKOTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CATTLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; MANNHEIMIA HAEMOLYTICA; MOLECULAR WEIGHT; NEUTROPHIL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SEROTYPE; SHEEP; TOXICITY TESTING;

EID: 0030940450     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/00222615-46-4-276     Document Type: Article

References (36)

1. Frank GH. Pasteurellosis of cattle. In: Adlam C, Rutter JM (eds) Pasteurella and pasteurellosis. London, Academic Press. 1989: 197-222.
2. Gilmour NJL, Gilmour JS. Pasteurellosis of sheep. In: Adlam C, Rutter JM (eds) Pasteurella and pasteurellosis. London, Academic Press. 1989: 223-262.
3. Sneath PH, Stevens M. Actinobacillus rossii sp. nov., Actinobacillus seminis sp. nov., nom. rev., Pasteurella bettii sp. nov., Pasteurella lymphangitidis sp. nov., Pasteurella mairi sp. nov., and Pasteurella trehalosi sp. nov. Int J Syst Bacteriol 1990; 40: 148-153.
4. Confer AW. Immunogens of Pasteurella. Vet Microbiol 1993; 37: 353-368.
5. Conlon JA, Shewen PE, Lo RYC. Efficacy of recombinant leukotoxin in protection against pneumonia challenge with live Pasteurella haemolytica A1. Infect Immun 1991; 59: 587-591.
6. Coote JG. The RTX toxins of Gram-negative bacterial pathogens: modulators of the host immune system. Rev Med Microbiol 1996; 7: 53-62.
7. Chang Y-F, Young R, Post D, Struck DK. Identification and characterization of the Pasteurella haemolytica leukotoxin. Infect Immun 1987; 55: 2348-2354.
8. Lo RYC, Strathdee CA, Shewen PE. Nucleotide sequence of the leukotoxin genes of Pasteurella haemolytica A1. Infect Immun 1987; 55: 1987-1996.
9. Shewen PE, Wilkie BN. Cytotoxin of Pasteurella haemolytica acting on bovine leukocytes. Infect Immun 1982; 35: 91-94.
10. Maheswaran SK, Kannan MS, Weiss DJ et al. Enhancement of neutrophil-mediated injury to bovine pulmonary endothelial cells by Pasteurella haemolytica leukotoxin. Infect Immun 1993; 61: 2618-2625.
11. 51chromium-release, trypan blue dye exclusion, and luminol-dependent chemiluminescence-inhibition assays for sensitivity in detecting leukotoxin activity. Am J Vet Res 1986; 47: 134-138.
12. Czuprynski CJ, Noel BJ. Influence of Pasteurella haemolytica A1 crude leukotoxin on bovine neutrophil chemiluminescence. Infect Immun 1990; 58: 1485-1487.
13. Ali Q, Davies RL, Parton R. Coote JG. Gibbs HA. Lipopolysaccharide heterogeneity in Pasteurella haemolytica isolates from cattle and sheep. J Gen Microbiol 1992; 138: 2185 2195.
14. Ali Q. Characterisation of virulence-related properties of Pasteurella haemolytica isolates. PhD Thesis 1992; Glasgow University.
15. McCluskey J, Gibbs HA, Davies RL. Variation in outer-membrane protein and lipopolysaccharide profiles of Pasteurella haemolytica isolates of serotypes A1 and A2 obtained from pneumonic and healthy cattle. Microbiology 1994; 140: 807-814.
16. Azad AK, Coote JG, Parton R. Distinct plasmid profiles of Pasteurella haemolytica serotypes and the characterization and amplification in Escherichia coli of ampicillin-resistance plasmids encoding ROB-1 β-lactamase. J Gen Microbiol 1992; 138: 1185-1196.
17. Davies RL, Ali Q, Parton R, Coote JG, Gibbs HA, Freer JH. Optimal conditions for the analysis of Pasteurella haemolytica lipopolysaccharide by sodium dodecyl sulphate-polyacrylamide gel electrophoresis. FEMS Microbiol Lett 1991: 90: 23 28.
18. Davies RL, Parton R, Coote JG, Gibbs HA, Freer JH. Outermembrane protein and lipopolysaccharide variation in Pasteurella haemolytica serotype A1 under different growth conditions. J Gen Microbiol 1992; 138: 909-922.
19. Shrceve BJ, Biberstein EL, Thompson DA. Variation in carrier rates of Pasteurella haemolytica in sheep. II. Diseased flocks. J Comp Pathol 1972; 82: 111-118.
20. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-685.
21. Towbin H, Stachelin T, Gordon J. Elcetrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76: 4350 4354.
22. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein, utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-257.
23. Strathdee CA, Lo RYC. Regulation of expression of the Pasteurella haemolytica leukotoxin determinant. J Bacteriol 1989; 171: 5955-5962.
24. Gatewood DM, Fenwick BW, Chengappa MM. Growth-condition dependent expression of Pasteurella haemolytica A1 outer membrane proteins, capsule, and leukotoxin. Vet Microbiol 1994; 41: 221-233.
25. Shewen PE, Wilkie BN. Evidence for the Pasteurella haemolytica cytotoxin as a product of actively growing bacteria. Am J Vet Res 1985; 46: 1212 1214.
26. Confer AW, Durham JA. Sequential development of antigens and toxins of Pasteurella haemolytica serotype 1 grown in cell culture medium. Am J Vet Res 1992; 53: 646 652.
27. Shewen PE, Wilkie BN. Pasteurella haemolytica cytotoxin: production by recognized serotypes and neutralization by type specific rabbit antisera. Am J Vet Res 1983; 44: 715 718.
28. Chang YF, Renshaw HW, Young R. Pneumonic pasteurellosis: examination of typable and untypable Pasteurella haemolytica strains for leukotoxin production, plasmid content, and antimicrobial susceptibility. Am J Vet Res 1987; 48: 378 384.
29. Gentry MJ, Confer AW, Holland SG. Comparison of the toxic and antigenic properties of single bovine isolates of Pusteurella haemolytica representing five serotypes and an untypable strain, Vet Microbiol 1988; 16: 351-367.
30. Gerbig DG, Cameron MR, Struck DK, Moore RN. Characterization of a neutralizing monoclonal antibody to Pasteurella haemolytica leukotoxin. Infect Immun 1992; 60: 1734-1739.
31. Winfield EO, Lo RYC. Analysis of the Pasteurella haemolytica T3 leukotoxin determinant. Abstracts of the General Meeting of the American Society for Microbiology, Dallas, Texas, 1991: 33.
32. Welch RA. Holistic perspective on the Escherichia coli hemolysin. In: Miller VL, Kaper JB, Portnoy DA, Isberg RR (eds) Molecular genetics of bacterial pathogenesis. A tribute to Stanley Falkow. Washington DC, ASM Press. 1994: 351-364.
33. Stanley PLD, Diaz P, Bailey MJA, Gygi D, Juarez A, Hughes C. Loss of activity in the secreted form of Escherichia coli haemolysin caused by an rfaP lesion in core lipopolysaccharide assembly. Mol Microbiol 1993; 10: 781-787.
34. Lo RYC. Molecular characterisation of the leukotoxin determinants of Pasteurella haemolytica serotypes 1-12. Annual Meeting of The American Society for Microbiology, Miami, Florida, 1988. Abstract B-60.
35. Burrows LL, Olah-Winfield E, Lo RYC. Molecular analysis of the leukotoxin determinants from Pasteurella haemolytica serotypes 1 to 16. Infect Immun 1993; 61: 5001-5007.
36. Frey J, Bosse JT, Chang Y-F et al. Actinobacillus pleuropneumoniae RTX toxins: uniform designation of haemolysins, cytolysins, pleurotoxin and their genes. J Gen Microbiol 1993; 139: 1723-1728.