Effects of random mutagenesis in a putative substrate-binding domain of geranylgeranyl diphosphate synthase upon intermediate formation and substrate specificity

Journal of Biochemistry

Volumn 121, Issue 4, 1997, Pages 696-704

  Ohnuma, Shin Ichi ^a   Hemmi, Hisashi ^a   Ohio, Chikara ^a,b   Nakane, Hiroyuki ^b   Nishino, Tokuzo ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOYOTA MOTOR CORPORATION   (Japan)

Author keywords

Enzyme mechanism; Farnesyl diphosphate; Geranylgeranyl diphosphate synthase; Isoprenoids; Prenyltransferase

Indexed keywords

DIMETHYLALLYLTRANSFERASE; FARNESYL TRANS TRANSFERASE; SYNTHETASE;

ARCHAEBACTERIUM; ARTICLE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GRAM NEGATIVE CHEMOLITHOTROPHIC AND METHANE PRODUCING BACTERIA; MICHAELIS CONSTANT; MUTAGENESIS; NONHUMAN;

ARCHAEA; NEGIBACTERIA; SULFOLOBUS ACIDOCALDARIUS;

EID: 0030940428     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021642     Document Type: Article

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