Risk factors and attributable mortality associated with superinfections in neutropenic patients with cancer

Clinical Infectious Diseases

Volumn 24, Issue 4, 1997, Pages 575-579

  Nucci, Marcio ^a   Spector, Nelson ^a   Bueno, Ana Paula ^a   Solza, Cristiana ^a   Perecmanis, Tatiana ^a   Bacha, Paulo Cesar ^a   Pulcheri, Wolmar ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ADOLESCENT; ADULT; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; CANCER; CENTRAL VENOUS CATHETER; CHILD; CLINICAL ARTICLE; FEVER; FUNGEMIA; HOSPITAL INFECTION; HUMAN; MORTALITY; MYCOSIS; NEUTROPENIA; PRIORITY JOURNAL; RISK FACTOR; SUPERINFECTION;

EID: 0030940120     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1093/clind/24.4.575     Document Type: Article

References (24)

1. Love LJ, Schimpff SC, Schiffer CA, Wiernik PH. Improved prognosis for granulocytopenic patients with gram-negative bacteremia. Am J Med 1980;68:643-8.
2. Dybedal I, Lamvik J. Respiratory insufficiency in acute leukemia following treatment with cytosine arabinoside and septicemia with streptococcus viridans [letter]. Eur J Haematol 1989;42:405-6.
3. Raad II, Bodey GP. Infectious complications of indwelling vascular catheters. Clin Infect Dis 1992;15:197-210.
4. McGowan JE Jr. Antimicrobial resistance in hospital organisms and its relation to antibiotic use. Rev Infect Dis 1983;5:1033-48.
5. Pittet D, Li N, Wenzel RP. Association of secondary and polymicrobial nosocomial bloodstream infections with higher mortality. Eur J Clin Microbiol Infect Dis 1993;12:813-9.
6. Wenzel RP. The mortality of hospital-acquired bloodstream infections: need for a new vital statistic? Int J Epidemiol 1988;17:225-7.
7. Bodey GP. Empirical antibiotic therapy for fever in neutropenic patients. Clin Infect Dis 1993;17(suppl 2):S378-84.
8. Jones PG, Rolston KVI, Fainstein V, Elting L, Walters RS, Bodey GP. Aztreonam therapy in neutropenic patients with cancer. Am J Med 1986;81:243-8.
9. Rolston KVI, Berkey P, Bodey GP, et al. A comparison of imipenem to ceftazidime with or without amikacin as empiric therapy in febrile neutropenic patients. Arch Intern Med 1992;152:283-91.
10. Bodey GP, Feld R, Burgess MA. β-Lactam antibiotics alone or in combination with gentamicin for therapy of gram-negative bacillary infections in neutropenic patients. Am J Med Sci 1976;271:179-86.
11. Richard P, Delangle M-H, Merrien D, et al. Fluoroquinolone use and fluoroquinolone resistance: is there an association? Clin Infect Dis 1994;19:54-9.
12. Cometta A, Calandra T, Bille J, Glauser MP. Escherichia coli resistant to fluoroquinolones in patients with cancer and neutropenia [letter]. N Engl J Med 1994;330:1240-1.
13. Pulcheri W, Spector N, Nucci M, de Morais JC, Pimenta G, de Oliveira HP. The treatment of acute myeloid leukemia in Brazil: progress and obstacles. Haematologica 1995;80:130-5.
14. Bodey GP. Fungal infections in cancer patients. Ann N Y Acad Sci 1988;544:431-42.
15. Serra P, Santini C, Venditti M, Mandelli F, Martino P. Superinfections during antimicrobial treatment with betalactam-aminoglycoside combinations in neutropenic patients with hematologic malignancies. Infection 1985;13(suppl 1):S115-22.
16. Romero-Vivas J, Rubio M, Fernandez C, Picazo JJ. Mortality associated with nosocomial bacteremia due to methicillin-resistant Staphylococcus aureus. Clin Infect Dis 1995;21:1417-23.
17. Pizzo PA, Ladisch S, Robichaud K. Treatment of gram-positive septicemia in cancer patients. Cancer 1980;45:206-7.
18. Feld R, Goodman PJ, Higgins B, et al. Prognostic factors for the development of superinfection in febrile neutropenic cancer patients [abstract no 1695]. In: Program and abstracts of the 32th Interscience Conference on Antimicrobial Agents and Chemotherapy (Anaheim). Washington, DC: American Society for Microbiology, 1992.
19. Wey SB, Mon M, Pfaller MA, Woolson RF, Wenzel RP. Risk factors for hospital-acquired candidemia: a matched case-control study. Arch Intern Med 1989;149:2349-53.
20. Johnson PR, Decker MD, Edwards KM, Schaffner W, Wright PF. Frequency of broviac catheter infections in pediatric oncology patients. J Infect Dis 1986;154:570-8.
21. Nucci M, Pulcheri WA, Spector N, de Oliveira HP. Ceftazidime and amikacin as empirical treatment of febrile episodes in neutropenic patients [letter]. J Infect 1994;28:335-6.
22. GIMEMA Infection Program. Prevention of bacterial infection in neutropenic patients with hematologic malignancies: a randomized, multicenter trial comparing norfloxacin with ciprofloxacin. Ann Intern Med 1991;115:7-12.
23. Pizzo PA. Management of fever in patients with cancer and treatmentinduced neutropenia. N Engl J Med 1993;328:1323-32.
24. Nucci M, Pulcheri W, Spector N, et al. Quinolone prophylaxis in neutropenic patients: efficacy versus resistance. Oncology Reports 1994;1:1101-5.