Investigation of plasma membrane-associated apolipoprotein E in primary macrophages

Journal of Lipid Research

Volumn 38, Issue 2, 1997, Pages 217-227

  Deng, Jiatai ^b   Rudick, Victoria ^a   Rudick, Michael ^c   Dory, Ladislav ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c TEXAS WOMAN'S UNIVERSITY   (United States)

Author keywords

glycosaminoglycans; heparan sulfate proteoglycans; HepG2 cells; lysosomes; trans Golgi network; xyloside

Indexed keywords

APOLIPOPROTEIN E; GLYCOSAMINOGLYCAN; HEPARIN; HEPARIN LYASE; XYLOSE;

ANIMAL CELL; ARTICLE; CELL STRAIN HEPG2; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOGOLD STAINING; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

ANIMALS; APOLIPOPROTEINS E; CELL LINE; CELL MEMBRANE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GOATS; HEPARIN; HEPARIN LYASE; HEPARITIN SULFATE; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES, PERITONEAL; MALE; MEMBRANE PROTEINS; METHIONINE; MICE; MIDDLE AGED; OLIGOPEPTIDES; POLYSACCHARIDE-LYASES; RABBITS; RATS; SULFUR RADIOISOTOPES; XYLOSE;

EID: 0030939941     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Kane, J. P., T. Sato, R. L. Hamilton, and R. J. Havel. 1975. Apoprotein composition of very low density lipoproteins of human serum. J. Clin. Invest. 56: 1622-1634.
2. Windler, E., Y. Chao, and R. J. Havel. 1980. Regulation of the hepatic uptake of triglyceride-rich lipoproteins in the rat. Opposing effects of homologous apolipoprotein E and individual C apoproteins. J. Biol. Chem. 255: 8303-8307.
3. Mahley, R. W., and T. L. Innerarity. 1983. Lipoprotein receptors and cholesterol homeostasis. Biochim. Biophys. Acta. 737: 197-222.
4. Brown, M. S., and J. L. Goldstein. 1986. A receptor-mediated pathway for cholesterol homeostasis. Science. 232: 34-47.
5. Kowal, R. C., J. Herz, J. L. Goldstein, V. Esser, and M. S. Brown. 1989. Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins. Proc. Natl. Acad. Sci. USA. 86: 5810-5814.
6. Hamilton, R. L., J. S. Wong, L. S. Guo, S. Krisans, and R. J. Havel. 1990. Apolipoprotein E localization in rat hepatocytes by immunogold labeling of cryothin sections. J. Lipid Res. 31: 1589-1603.
7. Lilly-Stauderman, M., T. L. Brown, A. Balasubramanian, and J. A. Harmony. 1993. Heparin releases newly synthesized cell surface-associated apolipoprotein E from HepG2 cells. J. Lipid Res. 34: 190-200.
8. Williams, D. L., J. S. Wong, S. L. Wissig, and R. L. Hamilton. 1995. Cell surface "blanket" of apolipoprotein E on rat adrenocortical cells. J. Lipid Res. 36: 745-758.
9. Leblond, L., and Y. L. Marcel. 1993. Uptake of high density lipoprotein cholesterol ester by HepG2 cells involves apolipoprotein E localized on the cell surface. J. Biol. Chem. 268: 1670-1676.
10. Ji, Z. S., W. J. Brecht, R. D. Miranda, M. M. Hussain, T. L. Innerarity, and R. W. Mahley. 1993. Role of heparan sulfate proleoglycans in the binding and uptake of apolipoprotein E-enriched remnant lipoproteins by cultured cells. J. Biol. Chem. 268: 10160-10167.
11. Ji, Z. S., S. Fazio, and R. W. Mahley. 1994. Variable heparan sulfate proteoglycan binding of apolipoprotein E variants may modulate the expression of type III hyperlipoproteinemia. J. Biol. Chem. 269: 13421-13428.
12. Ji, Z. S., S. Fazio, Y. L. Lee, and R. W. Mahley. 1994. Secretion-capture role for apolipoprotein E in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans. J. Biol. Chem. 269: 2764-2772.
13. Deng, J., V. L. Rudick, and L. Dory. 1995. Lysosomal degradation and sorting of apolipoprotein E in macrophages. J. Lipid Res. 36: 2129-2140.
14. Dory L. 1989. Synthesis and secretion of apoE in thioglycolate-elicited mouse peritoneal macrophages: effect of cholesterol efflux. J. Lipid Res. 30: 809-816.
15. 3 in mouse macrophages. J. Lipid Res. 32: 783-792.
16. Sato, T. 1968. A modified method for lead staining of thin sections. J. Electron Microsc. (Tokyo) 17: 62-63.
17. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275.
18. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T-4. Nature. 227: 680-685.
19. Weisgraber, K. H., R. C. Rall, Jr., R. W. Mahley, R. W. Milne, Y. L. Marcel, and J. T. Sparrow. 1986. Human apolipoprotein E. Determination of the heparin binding sites of apolipoprotein E3. J. Biol. Chem. 261: 2068-2076.
20. Cardin, A. D., N. Hirose, D. T. Blankenship, R. L. Jackson, J. A. Harmony, D. A. Sparrow, and J. T. Sparrow. 1986. Binding of a high reactive heparin to human apolipoprotein E: identification of two heparin-binding domains. Biochem. Biophys. Res. Commun. 134: 783-789.
21. Cary, D. J., C. M. Rafferty, and M. S. Todd. 1987. Effects of inhibition of proteoglycan synthesis on the differentiation of cultured rat Schwann cells. J. Cell Biol. 105: 1013-1021.
22. Shimada, K., and T. Ozawa. 1987. Modulation of glycosaminoglycan production and anti-thrombin II binding by cultured aortic endothelial cells treated with 4-methylumbelliferyl-β-D-xyloside. Arteriosclerosis. 7: 627-636.
23. Kjellen, L., and U. Lindahl. 1991. Proteoglycans: structures and interactions. Annu. Rev. Biochem. 60: 443-475.
24. Pierschbacher, M. D., and E. Ruoslahti. 1984. Variants of the cell recognition site of fibronectin that retain attachment-promoting activity. Proc. Natl. Acad. Sci. USA 81: 5985-5988.
25. Dedhar, S., E. Ruoslahti, and M. D. Pierschbacher. 1987. A cell surface receptor complex for collagen type 1 recognizes the Arg-Gly-Asp sequence. J. Cell Biol. 104: 585-593.
26. Gehlsen, K. R., W. S. Argraves, M. D. Pierschbacher, and E. Ruoslahti. 1988. Inhibition of in vitro tumor cell invasion by Arg-Gly-Asp-containing synthetic peptides. J. Cell Biol. 106: 925-930.
27. Arenson, D. M., S. L. Friedman, and D. Montgomery Bisséll. 1988. Formation of extracellular matrix in normal rat liver: lipocytes as a major source of proteoglycan. Gastroenterology 95: 441-447.
28. Gressner, A. M., and S. Schafer. 1989. Comparison of sulphated glycosaminoglycan and hyaluronate synthesis and secretion in cultured hepatocytes, fat storing cells and Kupffer cells. J. Clin. Chem. Clin. Biochem. 27: 141-149.
29. Santosh Babu, P. B., and P. R. Sudhakaram. 1991. Isolation of heparan sulfate proteoglycan from beneath the monolayers of rat hepatocytes and its binding to type IV collagen. J. Cell. Biochem. 46: 48-53.
30. Owens, R. T., and W. D. Wagner. 1991. Metabolism and turnover of cell surface-associated heparan sulfate proteoglycan and chondroitin sulfate proteoglycan in normal and cholesterol-enriched macrophages. Arterioscler. Thromb. 11: 1752-1758.
31. Owens, R. T., and W. D. Wagner. 1992. Chondroitin sulfate proteoglycan and heparan sulfate proteoglycan production by cultured pigeon peritoneal macrophages. J. Leucocyte Biol. 51: 626-633.
32. Yeaman, C., and A. C. Rapraeger. 1993. Membrane-associated proteoglycans of mouse macrophages: P388D1 cells express a syndecan-4-like heparan sulfate proteoglycan and a distinct chondroitin sulfate form. J. Cell. Physiol. 157: 413-425.
33. Petricevich, V. L., and Y. M. Michelacci. 1990. Proteoglycans synthesized in vitro by nude and normal mouse peritoneal macrophages. Biochim. Biophys. Acta. 1053: 135-143
34. Fogelman, A. M., B. J. Van Lenten, C. Warden, M. E. Haberland and P. A. Edwards. 1988. Macrophage lipoprotein receptors. J. Cell Sci. 9: 135-149.
35. Hoff, H. F., J. O'Neil, J. M. Pepin, and T. B. Cole. 1990. Macrophage uptake of cholesterol-containing particles derived from LDL and isolated from atherosclerotic lesions. Eur. Heart J. 11: (suppl.) 105-115.
36. Traber, M. G., B. Kallman, and H. J. Kayden. 1983. Localization of the binding sites of native and acetylated low-density lipoprotein (LDL) in human monocyte-denved macrophages. Exp. Cell Res. 15: 281-292.
37. Lucas, M., and T. Mazzone. 1996. Cell surface proteoglycans modulate net synthesis and secretion of macrophage apolipoprotein E. J. Biol. Chem. 271: 13454-13460.
38. Dietrich, C. P., H. A. Armelin, Y. L. Nogueira, H. B. Nader, and Y. M. Michelacci. 1982. Turnover, change of composition with rate of cell growth and effect of phenylxyloside on the synthesis and structure of cell surface sulfated glycosaminoglycans of normal and transformed cells. Biochim. Biophys. Acta. 717: 387-397.
39. Auwerx, J. H., S. Deeb, J. D. Brunzell, R. Peng, and A. Chait. 1988. Transcriptional activation of the lipoprotein lipase and apolipoprotein E genes accompanies differentiation in some human macrophage-like cell lines. Biochemistry. 27: 2651-2655.
40. Dory, L. 1993. Post-transcriptional regulation of apolipoprotein E expression in mouse macrophages by phorbol ester. Biochem. J. 292: 105-111.
41. Bernard, D., A. Rodriguez, G. H. Rothblat, and J. M. Glick 1990. Influence of high density lipoprotein on esterified cholesterol stores in macrophages and hepatoma cells. Arteriosclerosis. 10: 135-144.
42. Graham, A., A. D. Angell, C. A. Jepson, S. J. Yeaman, and D. G. Hassall. 1996. Impaired mobilisation of cholesterol from stored cholesteryl esters in human (THP-1) macrophages. Atherosclerosis. 120: 135-145.
43. Beisiegel, U., W. J. Weber, R. Havinga, G. Ihrke, D. Y. Hui, M. E. Wernette-Hammond, C. W. Turch, T. L. Innerarity, and R. W. Mahley. 1988. Apolipoprotein E-binding proteins isolated from dog and human liver. Arteriosclerosis. 8: 288-297.
44. Kishimoto, Y., M. Hiraiwa, and J. S. O'Brien. 1992. Saposins: structure, function, distribution, and molecular genetics. J. Lipid Res. 33: 1255-1267.
45. O'Brien, J. S., and Y. Kishimoto. 1991. Saposin proteins: structure, function, and role in human lysosomal storage disorders. FASEB J. 5: 301-308.
46. Zhu Y., and G. E. Conner. 1994. Intermolecular association of lysosomal protein precursors during biosynthesis. J. Biol. Chem. 4: 3846-3851.