Preparation, DNA binding, and in vitro cytotoxicity of a pair of enantiomeric platinum(II) complexes, [(R)- and (S)-3- aminohexahydroazepine]dichloroplatinum(II). Crystal structure of the S enantiomer

Journal of Medicinal Chemistry

Volumn 40, Issue 7, 1997, Pages 1090-1098

  Fenton, Ronald R ^a   Easdale, Warren J ^b   Er, H Meng ^a   O'Mara, Shaun M ^b   McKeage, Mark J ^b   Russell, Pamela J ^b   Hambley, Trevor W ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b PRINCE OF WALES HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

(3 AMINOHEXAHYDROAZEPINE)DICHLOROPLATINUM(II); CISPLATIN; PLATINUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CRYSTAL STRUCTURE; CYTOTOXICITY TEST; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANTINEOPLASTIC AGENTS; CRYSTALLOGRAPHY, X-RAY; DNA; HUMANS; MODELS, MOLECULAR; ORGANOMETALLIC COMPOUNDS; STEREOISOMERISM; TUMOR CELLS, CULTURED;

EID: 0030939923     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9607966     Document Type: Article

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