41. A Novel Approach towards 2,3,5-Trisubstituted Thiophenes via Tandem Michael Addition/Intramolecular Knoevenagel Condensation

Helvetica Chimica Acta

Volumn 80, Issue 2, 1997, Pages 531-537

  Obrecht, Daniel ^a,b   Gerber, Fernand ^a   Sprenger, Daniel ^a   Masquelin, Thierry ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b POLYPHOR Ltd   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

THIOPHENE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; TECHNIQUE;

EID: 0030939831     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.19970800217     Document Type: Article

References (18)

1. S. Gronowitz, Thiophene and its Derivatives', John Wiley and Sons, New York, 1992, Vol. 5, p. 802; T. A. Skotheim, Ed., 'Handbook of Conducting Polymers', M. Dekker, New York, 1986.
2. S. Gronowitz, Thiophene and its Derivatives', John Wiley and Sons, New York, 1992, Vol. 5, p. 802; T. A. Skotheim, Ed., 'Handbook of Conducting Polymers', M. Dekker, New York, 1986.
3. O. Hinsberg, Ber. Dtsch. Chem. Ges. 1910, 43, 901.
4. K. Gewald, E. Schinke, H. Böttcher, Chem. Ber. 1966, 99, 72; N. K. Son, R. Pinel, X. Molier, C. R. Acad. Sci. 1971, 273, 278; Bull. Chim. Soc. Fr. 1974, 471.
5. K. Gewald, E. Schinke, H. Böttcher, Chem. Ber. 1966, 99, 72; N. K. Son, R. Pinel, X. Molier, C. R. Acad. Sci. 1971, 273, 278; Bull. Chim. Soc. Fr. 1974, 471.
6. K. Gewald, E. Schinke, H. Böttcher, Chem. Ber. 1966, 99, 72; N. K. Son, R. Pinel, X. Molier, C. R. Acad. Sci. 1971, 273, 278; Bull. Chim. Soc. Fr. 1974, 471.
7. F. Buhlmann, E. Bresinsky, Chem. Ber. 1964, 97, 2109.
8. P. J. Fagan, W. A. Nugent, J. Am. Chem. Soc. 1988, 110, 2310; E. H. Braye, E. Hubel, Chem. Ind. 1959, 1250.
9. P. J. Fagan, W. A. Nugent, J. Am. Chem. Soc. 1988, 110, 2310; E. H. Braye, E. Hubel, Chem. Ind. 1959, 1250.
10. T. Masquelin, D. Obrecht, Tetrahedron Lett. 1994, 55, 9387.
11. T. Masquelin, D. Obrecht, Synthesis 1995, 276.
12. D. Obrecht, Helv. Chim. Acta 1989, 72, 447.
13. D. Obrecht, Helv. Chim. Acta 1991, 74, 27.
14. T. Masquelin, D. Obrecht, Tetrahedron 1997, 55, 641.
15. G. Kirsh, D. Prim, Synth. Commun. 1994, 24, 1721.
16. D. Obrecht, B. Weiss, Helv. Chim. Acta 1989, 72, 117.
17. T. Kubota, M. Iijima, T. Tanaka, Tetrahedron Lett. 1992, 55, 1352; T. Kitazume, J. Tai Lin, T. Yamazaki, Tetrahedron: Asymmetry, 1991, 2, 235.
18. T. Kubota, M. Iijima, T. Tanaka, Tetrahedron Lett. 1992, 55, 1352; T. Kitazume, J. Tai Lin, T. Yamazaki, Tetrahedron: Asymmetry, 1991, 2, 235.