Effects of neonatal dexamethasone treatment on hypothalamo-pituitary adrenal axis and immune system of the rat

Journal of Neuroimmunology

Volumn 74, Issue 1-2, 1997, Pages 69-76

  Bakker, Joost M ^a   Schmidt, E Donné ^a   Kroes, Hilde ^a   Kavelaars, Annemieke ^b   Heijnen, Cobi J ^b   Tilders, Fred J H ^a   Van Rees, Emmelien P ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

CRH neurons; glucocorticoids; HPA axis; neonatal; spleen; thymus

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CORTICOSTERONE; CORTICOTROPIN; DEXAMETHASONE SODIUM PHOSPHATE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DEVELOPMENT; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INTRAPERITONEAL DRUG ADMINISTRATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN; T LYMPHOCYTE SUBPOPULATION; THYMUS;

ANIMALS; ANIMALS, NEWBORN; ARGININE VASOPRESSIN; CD4-CD8 RATIO; CORTICOTROPIN-RELEASING HORMONE; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNE SYSTEM; MALE; MEDIAN EMINENCE; PITUITARY-ADRENAL SYSTEM; RATS; RATS, WISTAR; SPLEEN; T-LYMPHOCYTES; THYMUS GLAND;

EID: 0030939805     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(96)00207-X     Document Type: Article

References (41)

1. Alkalay, A.L., Pomerance, J.J., Puri, A.R., Lin, B.J.C., Vinstein, A.L., Neufeld, N.D. and Klein, A.H. (1990) Hypothalamic-pituitary-adrenal axis function in very low birthweight infants treated with dexamethasone. Pediatrics 86, 204-209.
2. Bakker, J.M., Schmidt, E.D., Kroes, H., Kavelaars, A., Heijnen, C.J., Tilders, F.J.H. and Van Rees, E.P. (1995) Effects of short-term dexamethasone treatment during pregnancy on the development of the immune system and the hypothalamo-pituitary adrenal axis in the rat. J. Neuroimmunol. 63, 183-191.
3. Benesova, O., Pavlik, A. (1988) Perinatal treatment with glucocorticoids and the risk of maldevelopment of the brain. Neuropharmacology 28, 89-97.
4. Berkenbosch, F., De Goeij, D.C.E. and Tilders, F.J.H. (1989) Hypoglycemia enhances turnover of corticotropin-releasing factor and of vasopressin in the zona externa of the rat median eminence. Endocrinology 125, 28-34.
5. Berkenbosch, F., Tilders, F.J.H. (1988) Effects of axonal transport blockade on corticotropin-releasing factor immunoreactivity in the median eminence of intact and adrenalectomized rats: Relationship between depletion rate and secretory activity. Brain Res. 442, 312-320.
6. Bhatnagar, S., Meaney, M.J. (1995) Hypothalamic-pituitary-adrenal function in chronic intermittently cold-stressed neonatally handled and non handled rats. J. Neuroendocrinol. 7, 97-108.
7. Cohen, J.J. (1992) Glucocorticoid-induced apoptosis in the thymus. Semin. Immunol. 4, 363-369.
8. Cummings, J.J., D'Eugenio, D.B. and Gross, S.J. (1989) A controlled trial of dexamethasone in preterm infants at high risk for bronchopulmonary dysplasia. N. Engl. J. Med. 320, 1505-1510.
9. De Goeij, D.C.E., Binnekade, R. and Tilders, F.J.H. (1992a) Chronic stress enhances vasopressin but not corticotropin-releasing factor secretion during hypoglycemia. Am. J. Physiol. 263, E394-E399.
10. De Goeij, D.C.E., Dijkstra, H. and Tilders, F.J.H. (1992b) Chronic psychosocial stress enhances vasopressin, but not corticotropin-releasing factor, in the external zone of the median eminence of male rats: Relationship to subordinate status. Endocrinology 131, 847-853.
11. De Kloet, E.R., Rosenfeld, P., van Eekelen, J.A.M., Sutanto, W. and Levine, S. (1988) Stress, glucocorticoids and development. In: G.J. Boer, M.G.P. Feenstra, M. Mirmiran, D.F. Swaab and F. Van Haaren (Eds.), Progress in Brain Research, Vol. 73. Elsevier Science Publishers B.V., Amsterdam, pp. 101-120.
12. Dobbing, J. (1970) Undernutrition and the developing brain. In: W.A. Himwich (Ed.), Developmental Neurobiology, Thomas, Springfield, pp. 241-261.
13. Dupouy, J.-P., Chatelain, A., Boudouresque, F., Conte-Devolx, B. and Oliver, C. (1987) Effects of chronic maternal dexamethasone treatment on the hormones of the hypothalamo-pituitary-adrenal axis in the rat fetus. Biol. Neonate 52, 216-222.
14. Jondal, M., Okret, S. and McConkey, D. (1993) Killing of immature CD4+ CD8+ thymocytes in vivo by anti-CD3 and or 5′-(N-ethyl)-carboxamide adenosine is blocked by glucocorticoid receptor antagonist RU-486. Eur. J. Immunol. 23, 1246-1250.
15. Kovacs, K.J., Makara, G.B. (1988) Corticosterone and dexamethasone act at different brain sites to inhibit adrenalectomy-induced adrenocorticotropin hypersecretion. Brain Res. 474, 205-210.
16. Krieger, D.T. (1974) Effect of neonatal hydrocortisone on corticosteroid circadian periodicity, responsiveness to ACTH and stress in prepuberal and adult rats. Neuroendocrinology 16, 355-363.
17. Levine, S. (1994) The ontogeny of the hypothalamic-pituitary-adrenal axis. Ann. N. Y. Acad. Sci. 746, 275-293.
18. Meaney, M.J., Aitken, D.H., Viau, V., Sharma, S. and Sarriau, A. (1989) Neonatal handling alters adrenocortical negative feedback sensitivity and hippocampal type II glucocorticoid receptor binding in the rat. Neuroendocrinology 50, 597-604.
19. Meyer, J.S. (1985) Biochemical effects of corticosteroids on neural tissues. Physiol. Rev. 65, 946-1020.
20. Miyabo, S., Hisada, T. (1975) Sex difference in ontogenesis of circadian adrenocortical rhythm in cortisone-primed rats. Nature 256, 590-592.
21. Morale, M.C., Batticane, N., Gallo, F., Barden, N. and Marchetti, B. (1995) Disruption of hypothalamic-pituitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: Effects on T cell trafficking and T cell responsiveness during postnatal development. Endocrinology 136, 3949-3960.
22. Nikolic-Zugic, J. (1991) Phenotypic and functional stages in the intrathymic development of αβT cells. Immunol. Today 12, 65-70.
23. + mature thymocytes require different post-selection processing for final development. J. Immunol. 151, 1273-1279.
24. Rosenfeld, P., Sutanto, W., Levine, S. and de Kloet, E.R. (1988a) Ontogeny of type I and type II corticosteroid receptors in the rat hippocampus. Dev. Brain. Res. 42, 113-118.
25. Rosenfeld, P., van Eekelen, J.A.M., Levine, S. and de Kloet, E.R. (1988b) Ontogeny of the type 2 glucocorticoid receptor in discrete rat brain regions: An immunocytochemical study. Dev. Brain. Res. 42, 119-127.
26. Sanders, R.J., Cox, C., Phelps, D.L. and Sinkin, R.A. (1994) Two doses of early intravenous dexamethasone for the prevention of bronchopulmonary dysplasia in babies with respiratory distress syndrome. Pediatr. Res. 36, 122-128.
27. Sapolski, R.M., Meaney, M.J. (1986) Maturation of the adrenocortical stress response: Neuroendocrine control mechanisms and the stress hyporesponsive period. Brain. Res. Rev. 11, 65-76.
28. Schmidt, E.D., Janszen, A.W.J.W., Wouterlood, F.G. and Tilders, F.J.H. (1995) Interleukin-1 -induced long-lasting changes in hypothalamic corticotropin-releasing hormone (CRH)-neurons and hyperresponsiveness of the hypothalamus-pituitary-adrenal axis. J. Neurosci. 15, 7417-7426.
29. Screpanti, I., Morrone, S., Meco, D., Santoni, A., Gulino, A., Paolini, R., Crisanti, A., Mathieson, B.J. and Frati, L. (1989) Steroid sensitivity of thymocyte subpopulations during intrathymic differentiation. J. Immunol. 142, 3378-3383.
30. Smolders-de Haas, H., Neuvel, J., Schmand, B., Treffers, P.E., Koppe, J.G. and Hoeks, J. (1990) Physical development and medical history of children who were treated antenatally with corticosteroids to prevent respiratory distress syndrome: A 10- to 12 year follow-up. Pediatrics 85, 65-70.
31. Suchecki, D., Mozaffarian, D., Gross, G., Rosenfeld, P. and Levine, S. (1993) Effects of maternal deprivation on the ACTH stress response in the infant rat. Neuroendocrinology 57, 204-212.
32. Sutanto, W., Rosenfeld, P., de Kloet, E.R. and Levine, S. (1996) Long-term effects of neonatal maternal deprivation and ACTH on hippocampal mineralocorticoid and glucocorticoid receptors. Dev. Brain. Res. 92, 156-163.
33. Tilders, F.J.H., De Goeij, D.C.E. and Berkenbosch, F. (1989) Turnover of corticotropin releasing factor and vasopressin in the median eminence and control of pituitary-adrenal activity. In: F.J. Rose (Ed.), The Control of the Hypothalamo-Pituitary-Adrenal Axis, International UP, Madison, WI, pp. 7-24.
34. Turner, B.B., Taylor, A.N. (1976) Persistent alteration of pituitaryadrenal function in the rat by prepuberal corticosterone treatment. Endocrinology 1-9.
35. Vacchio, M.S., Papadopoulos, V. and Ashwell, J.D. (1994) Steroid production in the thymus: Implications for thymocyte selection. J. Exp. Med. 1835-1846.
36. Van der Sluis, P.J., Pool, C.W. and Sluiter, A.A. (1988) Immunochemical detection of peptides and proteins on press-blots after direct tissue gel isoelectric focussing. Electrophoresis 9, 654-661.
37. Van Dijken, H.H., De Goeij, D.C.E., Sutanto, W., Mos, J., de Kloet, E.R. and Tilders, F.J.H. (1993) Short inescapable stress produces long-lasting changes in the brain-pituitary adrenal axis of adult male rats. Neuroendocrinology 58, 57-64.
38. Van Oers, J.W., Hinson, J.P., Binnekade, R. and Tilders, F.J.H. (1992) Physiological role of corticotropin-releasing factor in the control of adrenocorticotropin-mediated corticosterone release from the rat adrenal gland. Endocrinology 130, 282-288.
39. Wilson, D.M., Baldwin, R.B. and Ariagno, R.L. (1988) A randomized, placebo-controlled trial of effects of dexamethasone on hypothalamic-pituitary-adrenal axis in preterm infants. J. Pediatr. 113, 764-768.
40. Xue, Y., Murdjeva, M., Okret, S., McConkey, D., Kiuossis, D. and Jondal, M. (1996) Inhibition of I-Ad-, but not Db-restricted peptide-induced thymic apoptosis by glucocorticoid receptor antagonist RU486 in T cell receptor transgenic mice. Eur. J. Immunol. 26, 428-434.
41. Zoli, M., Agnati, L.F., Fuxe, K., Ferraguti, F., Biagini, G., Cintra, A. and Gustafsson, J.-A. (1990) Long-lasting reduction of glucocorticoid receptor immunoreactivity in the hippocampal field CAl but not in the dentate gyrus after neonatal treatment with corticosterone in the rat. Acta. Physiol. Scand. 138, 577-579.