메뉴 건너뛰기




Volumn 12, Issue 3, 1997, Pages 349-358

Proton magnetic resonance spectroscopy in dementia of Alzheimer type

Author keywords

Alzheimer's disease; Choline; Creatine; Dementia; Magnetic resonance spectroscopy; Myo inositol; N acetyl aspartate; Proton magnetic resonance spectroscopy

Indexed keywords

CHOLINE; CREATINE; INOSITOL; N ACETYLASPARTIC ACID;

EID: 0030939128     PISSN: 08856230     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1166(199703)12:3<349::AID-GPS508>3.0.CO;2-S     Document Type: Article
Times cited : (35)

References (62)
  • 5
    • 0014313861 scopus 로고
    • The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects
    • Blessed, G., Tomlinson, B. E. and Roth, M. (1968) The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Brit. J. Psychiat. 114, 797-811.
    • (1968) Brit. J. Psychiat. , vol.114 , pp. 797-811
    • Blessed, G.1    Tomlinson, B.E.2    Roth, M.3
  • 6
    • 0027476931 scopus 로고
    • Altered brain energy metabolism in demented patients with multiple subcortical ischemic lesions
    • Brown, G. G., Garcia, J. H., Gdowski, J. W., Levine, S. R. and Helpern, J. A. (1993) Altered brain energy metabolism in demented patients with multiple subcortical ischemic lesions. Arch. Neurol. 50, 384-388.
    • (1993) Arch. Neurol. , vol.50 , pp. 384-388
    • Brown, G.G.1    Garcia, J.H.2    Gdowski, J.W.3    Levine, S.R.4    Helpern, J.A.5
  • 8
    • 0026317199 scopus 로고
    • N-acetyl-L-aspartate is a major source of acetyl groups for lipid synthesis during rat brain development
    • Burri, R., Steffen, C. and Herschkowitz, N. (1991) N-acetyl-L-aspartate is a major source of acetyl groups for lipid synthesis during rat brain development. Dev. Neurosci. 13, 403-411.
    • (1991) Dev. Neurosci. , vol.13 , pp. 403-411
    • Burri, R.1    Steffen, C.2    Herschkowitz, N.3
  • 9
    • 0016177104 scopus 로고
    • Evaluating storage, retention, and retrieval in disordered memory and learning
    • Buschke, H. and Fuld, P. A. (1974) Evaluating storage, retention, and retrieval in disordered memory and learning. Neurology 24, 1019-1025.
    • (1974) Neurology , vol.24 , pp. 1019-1025
    • Buschke, H.1    Fuld, P.A.2
  • 11
    • 0027169607 scopus 로고
    • The concentration of N-acetyl aspartate, creatine + phosphocreatine, and choline in different parts of the brain in adulthood and senium
    • Christiansen, P., Toft, P., Larsson, H. B. W., Stubgaard, M. and Henriksen, O. (1993) The concentration of N-acetyl aspartate, creatine + phosphocreatine, and choline in different parts of the brain in adulthood and senium. Magn. Reson. Imag. 11, 799-806.
    • (1993) Magn. Reson. Imag. , vol.11 , pp. 799-806
    • Christiansen, P.1    Toft, P.2    Larsson, H.B.W.3    Stubgaard, M.4    Henriksen, O.5
  • 12
    • 0027184842 scopus 로고
    • A multiparametric data analysis showing the potential of localized proton MR spectroscopy of the brain in the metabolic characterization of neurological diseases
    • Confort-Gouny, S., Vion-Dury, J., Nicoli, F., Dano, P., Donnet, A., Grazziani, N., Gastaut, J. L., Grisoli, F. and Cozzone, P. J. (1993) A multiparametric data analysis showing the potential of localized proton MR spectroscopy of the brain in the metabolic characterization of neurological diseases. J. Neurol. Sci. 118, 123-133.
    • (1993) J. Neurol. Sci. , vol.118 , pp. 123-133
    • Confort-Gouny, S.1    Vion-Dury, J.2    Nicoli, F.3    Dano, P.4    Donnet, A.5    Grazziani, N.6    Gastaut, J.L.7    Grisoli, F.8    Cozzone, P.J.9
  • 13
    • 0014378844 scopus 로고
    • Acetyl transport mechanisms. Involvement of N-acetyl aspartic acid in de novo fatty acid biosynthesis in the developing rat brain
    • D'Adamo, A. F., Gidez, L. I. and Yatsu, F. M. (1968) Acetyl transport mechanisms. Involvement of N-acetyl aspartic acid in de novo fatty acid biosynthesis in the developing rat brain. Exp. Brain Res. 5, 267-273.
    • (1968) Exp. Brain Res. , vol.5 , pp. 267-273
    • D'Adamo, A.F.1    Gidez, L.I.2    Yatsu, F.M.3
  • 14
    • 0022578902 scopus 로고
    • In vivo tissue analysis by NMR spectroscopy
    • Den Hollander, J. A. (1986) In vivo tissue analysis by NMR spectroscopy. Diagn. Imag. Clin. Med. 55, 9-19.
    • (1986) Diagn. Imag. Clin. Med. , vol.55 , pp. 9-19
    • Den Hollander, J.A.1
  • 16
    • 0016823810 scopus 로고
    • 'Mini-Mental State'. A practical method for grading the cognitive state of patients for the clinician
    • Folstein, M. F., Folstein, S. E. and McHugh, P. R. (1975) 'Mini-Mental State'. A practical method for grading the cognitive state of patients for the clinician. J. Psychiat. Res. 12, 189-198.
    • (1975) J. Psychiat. Res. , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 17
    • 0024370099 scopus 로고
    • Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites
    • Frahm, J., Bruhn, H., Gyngell, M. L., Merboldt, K. D., Hänicke, W. and Sauter, R. (1989) Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites. Magn. Reson. Med. 11, 47-63.
    • (1989) Magn. Reson. Med. , vol.11 , pp. 47-63
    • Frahm, J.1    Bruhn, H.2    Gyngell, M.L.3    Merboldt, K.D.4    Hänicke, W.5    Sauter, R.6
  • 18
    • 0026001547 scopus 로고
    • Lokalisierte Protonen-MR-Spektroskopie. Nichtinvasive Einblicke in den Hirnstoffwechsel
    • Frahm, J., Bruhn, H., Michaelis, T., Merboldt, K. D., Hänicke, W. and Gyngell, M. L. (1991) Lokalisierte Protonen-MR-Spektroskopie. Nichtinvasive Einblicke in den Hirnstoffwechsel. Radiologe 31, 558-566.
    • (1991) Radiologe , vol.31 , pp. 558-566
    • Frahm, J.1    Bruhn, H.2    Michaelis, T.3    Merboldt, K.D.4    Hänicke, W.5    Gyngell, M.L.6
  • 19
    • 0027319229 scopus 로고
    • Advances in proton magnetic resonance spectroscopy of the brain
    • Gadian, D. G. (1993) Advances in proton magnetic resonance spectroscopy of the brain. Magn. Reson. Med. 30, 1-3.
    • (1993) Magn. Reson. Med. , vol.30 , pp. 1-3
    • Gadian, D.G.1
  • 20
    • 0028329158 scopus 로고
    • Magnetic resonance spectroscopy of N-acetylaspartate in hypoxic-ischemic encephalopathy
    • Graham, S. H., Meyerhoff, D. J., Bayne, L., Sharp, F. R. and Weiner, M. W. (1994) Magnetic resonance spectroscopy of N-acetylaspartate in hypoxic-ischemic encephalopathy. Ann. Neurol. 35, 490-494.
    • (1994) Ann. Neurol. , vol.35 , pp. 490-494
    • Graham, S.H.1    Meyerhoff, D.J.2    Bayne, L.3    Sharp, F.R.4    Weiner, M.W.5
  • 22
    • 0028037077 scopus 로고
    • Proton magnetic resonance spectroscopy studies on human brain myo-inositol in hypoosmolarity and hepatic encephalopathy
    • Häussinger, D., Laubenberger, J., vom Dahl, S., Ernst, T., Bayer, S., Langer, M., Gerok, W. and Hennig, J. (1994) Proton magnetic resonance spectroscopy studies on human brain myo-inositol in hypoosmolarity and hepatic encephalopathy. Gastroenterology 107, 1475-1480.
    • (1994) Gastroenterology , vol.107 , pp. 1475-1480
    • Häussinger, D.1    Laubenberger, J.2    Vom Dahl, S.3    Ernst, T.4    Bayer, S.5    Langer, M.6    Gerok, W.7    Hennig, J.8
  • 25
    • 0015677794 scopus 로고
    • The Set test as an aid to the detection of dementia in old people
    • Isaacs, B. and Kennie, A. T. (1973) The Set test as an aid to the detection of dementia in old people. Brit. J. Psychiat. 123, 467-470.
    • (1973) Brit. J. Psychiat. , vol.123 , pp. 467-470
    • Isaacs, B.1    Kennie, A.T.2
  • 26
    • 0025195996 scopus 로고
    • 1H in vivo NMR spectroscopy of small-volume elements in human brain at 1.5 T
    • 1H in vivo NMR spectroscopy of small-volume elements in human brain at 1.5 T. Magn. Reson. Med. 15, 320-326.
    • (1990) Magn. Reson. Med. , vol.15 , pp. 320-326
    • Jung, W.I.1    Grodd, W.2    Lutz, O.3    Petersen, D.4
  • 27
    • 0027340710 scopus 로고
    • 1H nuclear magnetic resonance spectroscopy identifies neural cell types: A promising step for neuroimaging?
    • 1H nuclear magnetic resonance spectroscopy identifies neural cell types: A promising step for neuroimaging? TINS 16, 384-386.
    • (1993) TINS , vol.16 , pp. 384-386
    • Kauppinen, R.A.1
  • 28
    • 0027465616 scopus 로고
    • Applications of magnetic resonance spectroscopy and diffusion-weighted imaging to the study of brain biochemistry and pathology
    • Kauppinen, R. A., Williams, S. R., Busza, A. L. and van Bruggen, N. (1993) Applications of magnetic resonance spectroscopy and diffusion-weighted imaging to the study of brain biochemistry and pathology. TINS 16, 88-95.
    • (1993) TINS , vol.16 , pp. 88-95
    • Kauppinen, R.A.1    Williams, S.R.2    Busza, A.L.3    Van Bruggen, N.4
  • 29
    • 0025766921 scopus 로고
    • Magnetic resonance spectroscopy in psychiatry: Potential, pitfalls and promise 1991
    • Keshavan, M. S., Kapur, S. and Pettegrew, J. W. (1991) Magnetic resonance spectroscopy in psychiatry: Potential, pitfalls and promise 1991. Am. J. Psychiat. 148, 976-985.
    • (1991) Am. J. Psychiat. , vol.148 , pp. 976-985
    • Keshavan, M.S.1    Kapur, S.2    Pettegrew, J.W.3
  • 30
    • 0026726198 scopus 로고
    • N-acetyl-L-aspartate and other amino acid metabolites in Alzheimer's disease brain: A preliminary proton nuclear magnetic resonance study
    • Klunk, W. E., Panchalingam, K., Moossy, J., McClure, R. J. and Pettegrew, J. W. (1992) N-acetyl-L-aspartate and other amino acid metabolites in Alzheimer's disease brain: A preliminary proton nuclear magnetic resonance study. Neurology 42, 1578-1585.
    • (1992) Neurology , vol.42 , pp. 1578-1585
    • Klunk, W.E.1    Panchalingam, K.2    Moossy, J.3    McClure, R.J.4    Pettegrew, J.W.5
  • 33
    • 0026541298 scopus 로고
    • Metabolic disorders of the brain in chronic hepatic encephalopathy detected with H-1 MR spectroscopy
    • Kreis, R., Ross, B. D., Farrow, N. A. and Ackerman, Z. (1992) Metabolic disorders of the brain in chronic hepatic encephalopathy detected with H-1 MR spectroscopy. Radiology 182, 19-27.
    • (1992) Radiology , vol.182 , pp. 19-27
    • Kreis, R.1    Ross, B.D.2    Farrow, N.A.3    Ackerman, Z.4
  • 34
    • 0027508313 scopus 로고
    • Alterations of brain metabolites in metachromatic leukodystrophy as detected by localized proton magnetic resonance spectroscopy in vivo
    • Kruse, B., Hanefeld, F., Christen, H. J., Bruhn, H., Michaelis, T., Hänicke, W. and Frahm, J. (1993) Alterations of brain metabolites in metachromatic leukodystrophy as detected by localized proton magnetic resonance spectroscopy in vivo. J. Neurol. 241, 68-74.
    • (1993) J. Neurol. , vol.241 , pp. 68-74
    • Kruse, B.1    Hanefeld, F.2    Christen, H.J.3    Bruhn, H.4    Michaelis, T.5    Hänicke, W.6    Frahm, J.7
  • 35
    • 0025241560 scopus 로고
    • Psychiatry and the new magnetic resonance era
    • Lock, T., Abou-Saleh, M. T. and Edwards, R. H. T. (1990) Psychiatry and the new magnetic resonance era. Brit. J. Psychiat, 157 (Suppl. 9), 38-55.
    • (1990) Brit. J. Psychiat , vol.157 , Issue.9 SUPPL. , pp. 38-55
    • Lock, T.1    Abou-Saleh, M.T.2    Edwards, R.H.T.3
  • 36
    • 0026149114 scopus 로고
    • Acquisition and quantitation in proton spectroscopy
    • Luyten, P. R., Marien, A. J. H. and den Hollander, J. A. (1991) Acquisition and quantitation in proton spectroscopy. NMR Biomed. 4, 64-69.
    • (1991) NMR Biomed. , vol.4 , pp. 64-69
    • Luyten, P.R.1    Marien, A.J.H.2    Den Hollander, J.A.3
  • 38
    • 0028290204 scopus 로고
    • Axonal injury and membrane alterations in Alzheimer's disease suggested by in vivo proton magnetic resonance spectroscopic imaging
    • Meyerhoff, D. J., MacKay, S., Constans, J.-M., Norman, D., Van Dyke, C., Fein, G. and Weiner, M.W. (1994) Axonal injury and membrane alterations in Alzheimer's disease suggested by in vivo proton magnetic resonance spectroscopic imaging. Ann. Neurol. 36, 40-47.
    • (1994) Ann. Neurol. , vol.36 , pp. 40-47
    • Meyerhoff, D.J.1    MacKay, S.2    Constans, J.-M.3    Norman, D.4    Van Dyke, C.5    Fein, G.6    Weiner, M.W.7
  • 40
    • 0026147120 scopus 로고
    • 1H NMR spectroscopy: N-acetyl-L-aspartate, creatine and choline
    • 1H NMR spectroscopy: N-acetyl-L-aspartate, creatine and choline. NMR Biomed. 4, 47-52.
    • (1991) NMR Biomed. , vol.4 , pp. 47-52
    • Miller, B.L.1
  • 41
    • 0027322890 scopus 로고
    • Alzheimer disease: Depiction of increased cerebral myo-inositol with proton MR spectroscopy
    • Miller, B. L., Moats, R. A., Shonk, T., Ernst, T., Woolley, S. and Ross, B. D. (1993) Alzheimer disease: Depiction of increased cerebral myo-inositol with proton MR spectroscopy. Radiology 187, 433-437.
    • (1993) Radiology , vol.187 , pp. 433-437
    • Miller, B.L.1    Moats, R.A.2    Shonk, T.3    Ernst, T.4    Woolley, S.5    Ross, B.D.6
  • 42
    • 0028244281 scopus 로고
    • Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease
    • Moats, R. A., Ernst, T., Shonk, T. K. and Ross, B. D. (1994) Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease. Magn. Reson. Med. 32, 110-115.
    • (1994) Magn. Reson. Med. , vol.32 , pp. 110-115
    • Moats, R.A.1    Ernst, T.2    Shonk, T.K.3    Ross, B.D.4
  • 43
    • 0025871390 scopus 로고
    • In vivo proton magnetic resonance spectroscopy studies of human brain
    • Narayana, P. A., Johnston, D. and Flamig, D. P. (1991) In vivo proton magnetic resonance spectroscopy studies of human brain. Magn. Reson. Imag. 9, 303-308.
    • (1991) Magn. Reson. Imag. , vol.9 , pp. 303-308
    • Narayana, P.A.1    Johnston, D.2    Flamig, D.P.3
  • 46
    • 0028326937 scopus 로고
    • Alterations of cerebral metabolism in probable Alzheimer's disease: A preliminary study
    • Pettegrew, J. W., Panchalingam, K., Klunk, W. E., McClure, R. J. and Muenz, L. R. (1994) Alterations of cerebral metabolism in probable Alzheimer's disease: A preliminary study. Neurobiol. Aging 15, 117-132.
    • (1994) Neurobiol. Aging , vol.15 , pp. 117-132
    • Pettegrew, J.W.1    Panchalingam, K.2    Klunk, W.E.3    McClure, R.J.4    Muenz, L.R.5
  • 47
    • 0027265566 scopus 로고
    • Human brain: Proton diffusion MR spectroscopy
    • Posse, S., Cuenod, C. A. and Le Bihan, D. (1993) Human brain: Proton diffusion MR spectroscopy. Radiology 188, 719-725.
    • (1993) Radiology , vol.188 , pp. 719-725
    • Posse, S.1    Cuenod, C.A.2    Le Bihan, D.3
  • 48
    • 0027769929 scopus 로고
    • The role of nuclear magnetic resonance imaging in psychiatric research
    • Potts, N. L. S., Davidson, J. R. T. and Krishnan, K. R. R. (1993) The role of nuclear magnetic resonance imaging in psychiatric research. J. Clin. Psychiat. 54 (Suppl. 12), 13-18.
    • (1993) J. Clin. Psychiat. , vol.54 , Issue.12 SUPPL. , pp. 13-18
    • Potts, N.L.S.1    Davidson, J.R.T.2    Krishnan, K.R.R.3
  • 49
    • 0028907520 scopus 로고
    • Temporal lobe proton magnetic resonance spectroscopy of patients with first-episode psychosis
    • Renshaw, P. R., Yurgelun-Todd, D. A., Tohen, M., Gruber, S. and Cohen, B. M. (1995) Temporal lobe proton magnetic resonance spectroscopy of patients with first-episode psychosis. Am. J. Psychiat. 152, 444-446.
    • (1995) Am. J. Psychiat. , vol.152 , pp. 444-446
    • Renshaw, P.R.1    Yurgelun-Todd, D.A.2    Tohen, M.3    Gruber, S.4    Cohen, B.M.5
  • 50
    • 0026145805 scopus 로고
    • 1H spectroscopy. Glutamate and glutamine; myoinositol and related metabolites
    • 1H spectroscopy. Glutamate and glutamine; myoinositol and related metabolites. NMR Biomed. 4, 59-63.
    • (1991) NMR Biomed. , vol.4 , pp. 59-63
    • Ross, B.D.1
  • 51
    • 0026833002 scopus 로고
    • Clinical tools for the 90s: Magnetic resonance spectroscopy and metabolite imaging
    • Ross, B., Kreis, R. and Ernst, T. (1992) Clinical tools for the 90s: Magnetic resonance spectroscopy and metabolite imaging. Eur. J. Radiol. 14, 128-140.
    • (1992) Eur. J. Radiol. , vol.14 , pp. 128-140
    • Ross, B.1    Kreis, R.2    Ernst, T.3
  • 52
    • 0026700701 scopus 로고
    • Proton magnetic resonance spectroscopy of human brain: Applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities
    • Sappey-Marinier, D., Calabrese, G., Hetherington, H. P., Fisher, S. N. G., Deicken, R., van Dyke, C., Fein, G. and Weiner, M. W. (1992) Proton magnetic resonance spectroscopy of human brain: Applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities. Magn. Reson. Med. 26, 313-327.
    • (1992) Magn. Reson. Med. , vol.26 , pp. 313-327
    • Sappey-Marinier, D.1    Calabrese, G.2    Hetherington, H.P.3    Fisher, S.N.G.4    Deicken, R.5    Van Dyke, C.6    Fein, G.7    Weiner, M.W.8
  • 53
    • 0025345687 scopus 로고
    • The human brain: Localized H-1 MR spectroscopy at 1.0 T
    • Sauter, R., Loeffler, W., Bruhn, H. and Frahm, J. (1990) The human brain: Localized H-1 MR spectroscopy at 1.0 T. Radiology 176, 221-224.
    • (1990) Radiology , vol.176 , pp. 221-224
    • Sauter, R.1    Loeffler, W.2    Bruhn, H.3    Frahm, J.4
  • 57
    • 0028870259 scopus 로고
    • Cerebral white matter in the centrum semiovale exhibits a larger N-acetyl signal than does gray matter in long echo time 1H-magnetic resonance spectroscopic imaging
    • Tedeschi, G., Righini, A., Bizzi, A., Barnett, A. S. and Alger, J. R. (1995) Cerebral white matter in the centrum semiovale exhibits a larger N-acetyl signal than does gray matter in long echo time 1H-magnetic resonance spectroscopic imaging. Magn. Reson. Med. 33, 127-133.
    • (1995) Magn. Reson. Med. , vol.33 , pp. 127-133
    • Tedeschi, G.1    Righini, A.2    Bizzi, A.3    Barnett, A.S.4    Alger, J.R.5
  • 58
    • 0026633564 scopus 로고
    • Specific expression of N-acetylaspartate in neurons, oligodendrocyte-type-2 astrocyte progenitors, and immature oligodendrocytes in vitro
    • Urenjak, J., Williams, S. R., Gadian, D. G. and Noble, M. (1992) Specific expression of N-acetylaspartate in neurons, oligodendrocyte-type-2 astrocyte progenitors, and immature oligodendrocytes in vitro. J. Neurochem. 59, 55-61.
    • (1992) J. Neurochem. , vol.59 , pp. 55-61
    • Urenjak, J.1    Williams, S.R.2    Gadian, D.G.3    Noble, M.4
  • 59
    • 0027450301 scopus 로고
    • Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types
    • Urenjak, J., Williams, S. R., Gadian, D. G. and Noble, M. (1993) Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types. J. Neurosci. 13, 981-989.
    • (1993) J. Neurosci. , vol.13 , pp. 981-989
    • Urenjak, J.1    Williams, S.R.2    Gadian, D.G.3    Noble, M.4
  • 61
    • 0028358432 scopus 로고
    • What might be the impact on neurology of the analysis of brain metabolism by in vivo magnetic resonance spectroscopy?
    • Vion-Dury, J., Meyerhoff, D. J., Cozzone, P. J. and Weiner, M. W. (1994) What might be the impact on neurology of the analysis of brain metabolism by in vivo magnetic resonance spectroscopy? J. Neurol. 241, 354-371.
    • (1994) J. Neurol. , vol.241 , pp. 354-371
    • Vion-Dury, J.1    Meyerhoff, D.J.2    Cozzone, P.J.3    Weiner, M.W.4
  • 62
    • 0025904240 scopus 로고
    • SIDAM - A structured interview for the diagnosis of dementia of the Alzheimer type, multi-infarct dementia and dementias of other aetiology according to ICD-10 and DSM-III-R
    • Zaudig, M., Mittelhammer, J., Hiller, W., Pauls, A., Thora, C., Morinigo, A. and Mombour, W. (1991) SIDAM - A structured interview for the diagnosis of dementia of the Alzheimer type, multi-infarct dementia and dementias of other aetiology according to ICD-10 and DSM-III-R. Psychol. Med. 21, 225-236.
    • (1991) Psychol. Med. , vol.21 , pp. 225-236
    • Zaudig, M.1    Mittelhammer, J.2    Hiller, W.3    Pauls, A.4    Thora, C.5    Morinigo, A.6    Mombour, W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.