Alanine dosimetry of proton therapy beams

Medical Physics

Volumn 24, Issue 3, 1997, Pages 447-453

  Onori, S ^a   D'Errico, F ^b   De Angelis, C ^a   Egger, E ^c   Fattibene, P ^a   Janovsky, I ^d  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PAUL SCHERRER INSTITUTE   (Switzerland)

^d NUCLEAR RESEARCH INSTITUTE   (Czech Republic)

Author keywords

alanine dosimetry; proton therapy

Indexed keywords

AMINO ACIDS; DOSIMETRY; PROTON BEAMS; THICK FILMS;

ALANINE DOSIMETRY; EXPERIMENTAL UNCERTAINTY; MARKUS CHAMBERS; PARALLEL PLATES; PROTON THERAPY; PROTON THERAPY BEAMS; REFERENCE DOSIMETRY; TISSUE EQUIVALENT PHANTOM;

PROTON BEAM THERAPY;

ALANINE;

ARTICLE; BEAM THERAPY; DOSIMETRY; ELECTRON SPIN RESONANCE; GAMMA RADIATION; PRIORITY JOURNAL; PROTON RADIATION; RADIATION DOSE;

EID: 0030939093     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.597911     Document Type: Article

References (23)

1. ASTM, American Society for Testing and Materials, "Standard Practice for use of the alanine-EPR dosimetry system," ASTM E1670-94, 1995 Annual Book of ASTM Standards, 1995, Vol. 12.02 (ASTM, Philadelphia, PA).
2. D W. Miller, "A review of proton beam radiation therapy," Med. Phys 22, 1943-1954 (1995).
3. S. Zink, "Proton dosimetry at ITEP accelerator using alanine and radiochromic detectors: A preliminary study," presented at the XVII PTCOG Meeting, Loma Linda, CA, October 1992.
4. D. Nichiporov, V. Kostjuchenko, J. M. Puhl, D. L. Bensen, M. F. Desrosiers, C. E. Dick, W. L. McLaughlin, T. Kojima, B. M. Coursey, and S Zink, "Investigation of applicability of alanine and radiochromic detectors to dosimetry of proton clinical beams," Appl. Radiat. Isot 46, 1355-1362 (1995).
5. A Bartolotta, P L. Indovina, S. Onori, and A. Rosati, "Dosimetry for Cobalt-60 gamma-rays with alanine," Radiat. Prot. Dos. 9, 277-281 (1984).
6. I. Janovsky, "Progress in alanine films/ESR dosimetry, Proceedings of International Symposium on High Dosimetry Radiation Processing (IAEA, Vienna, 1990), IAEA-SM-314/47, pp. 173-187.
7. C. Markovits, S. Jaccard, and C. Perret, "The proton beam facility OPTIS for the therapy of ocular tumors," Proceedings of the 12th International Conference on Cyclotrons and Their Applications, edited by B. Martin and K. Ziegler (World Scientific, Singapore, 1989), p 507.
8. S Vynckier, D. E. Bonnett, and D. T. L Jones, "Code of practice for clinical proton dosimetry," Radiother. Oncol. 20, 53-63 (1991).
9. S. Vynckier, D E. Bonnett, and D. T. L. Jones, "Supplement to the code of practice for clinical proton dosimetry," Radiother. Oncol 32, 174-179 (1994).
10. ICRU, International Commission on Radiation Units and Measurements, "Stopping powers and ranges for protons and alpha particles," Report No. 49, Bethesda, MD, CRU, 1993.
11. ICRU, International Commission on Radiation Units and Measurements, "Tissue Substitutes in Radiation dosimetry and measurements," Report No. 44, Bethesda, MD, CRU, 1989.
12. A. Wieser, C. Lettau, U. Fill, and D. F. Regulla, "The influence of non-radiation induced ESR background signal from paraffin-alanine probes for dosimetry in the radiotherapy dose range," Appl. Radiat. Isot. 44, 59-65 (1993).
13. A Bartolotta, P. Fattibene, S. Onori, M. Pantaloni, and E. Petetti, "Sources of uncertainty in therapy level alanine dosimetry," Appl. Radiat. Isot. 44, 13-17 (1993).
14. B. Ciesielski and L. Wielopolski, "The effects of dose and radiation quality on the shape and power saturation of the EPR signal in alanine," Radiat. Res. 140, 105-111 (1994).
15. D. F. Regulla and U. Deffner, "Dosimetry by ESR spectroscopy of alanine," Appl. Radiat. Isot. 33, 1101-1114 (1982).
16. D. I. Thwaites, "Bragg's rule of stopping power additivity: A compilation and summary of results," Radiat. Res. 95, 495-518 (1983).
17. J. W. Hansen and K. J. Olsen, "Theoretical and experimental radiation effectiveness of the free radical dosimeter alanine to irradiation with heavy charged particles," Radiat. Res 104, 15-27 (1985).
18. M. P. R. Waligorski, G. Danialy, K. S. Loh, and R. Katz, "The response of the alanine detector after charged-particle and neutron irradiations," Appl. Radiat Isot. 40, 923-933 (1989).
19. M. Goiten and J. M. Sisterson, "The influence of thick inhomogeneities on charged particle beams," Radiat. Res. 74, 217-230 (1978).
20. M. Urie, M. Goiten, W. R Holley, and G. T. Y. Chen, "Degradation of the Bragg peak due to inhomogeneities," Phys. Med. Biol. 31, 1-15 (1986)
21. A. Bartolotta, S. Onori, and M Pantaloni, "Alanine EPR dosimetry as a travelling dosimetric system for intercomparison purposes," Radiat Phys. Chem. 35, 708-712 (1990).
22. J. W. Hansen and K. J. Olsen, "Predicting decay in free-radical concentration in L-alpha alanine following high-LET radiation exposure," Appl. Radiat. Isot. 40, 935-940 (1989).
23. J. M. Arber and P H. G. Sharpe, "Fading characteristics of irradiated alanine pellets: The importance of pre-irradiation conditioning," Appl. Radiat. Isot. 44, 19-22 (1993).