Frequency of gastroesophageal reflux events induced by pharyngeal water stimulation in young and elderly subjects

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 272, Issue 2 35-2, 1997, Pages

  Xie, Pengyan ^a   Ren, Junlong ^b   Bardan, Eytan ^b   Mittal, Ravinder K ^c   Sui, Zhumei ^b   Shaker, Reza ^b,d  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^d FROEDTERT MEMORIAL LUTHERAN HOSPITAL   (United States)

Author keywords

aging; aging and lower esophageal sphincter length; intra abdominal and intrathoracic lower esophageal sphincter length; lower esophageal sphincter length; lower esophageal sphincter relaxation; pharyngeal sensory impulses

Indexed keywords

ADULT; AGED; AGING; ARTICLE; ESOPHAGUS MANOMETRY; FEMALE; GASTROESOPHAGEAL REFLUX; HUMAN; HUMAN EXPERIMENT; LOWER ESOPHAGUS SPHINCTER; MALE; PERISTALSIS; PHARYNX; PRIORITY JOURNAL; SENSORY STIMULATION; SWALLOWING;

EID: 0030938682     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1997.272.2.g233     Document Type: Article

References (20)

1. Dean, R., K. Dua, B. Massey, W. Berger, W. J. Hogan, and R. Shaker. A comparative study of unsedated transnasal esophagogastroduodenoscopy (T-EGD) and conventional EGD. Gastrointest. Endosc. 44: 422-424, 1996.
2. DeMeester, T. R., J. A. Wernly, G. H. Bryant, A. G. Little, and D. B. Skinner. Clinical and in vitro analysis of determinants of gastroesophageal competence. Am. J. Surg. 137: 39-46, 1979.
3. Dent, J., W. J. Dodds, R. H. Friedman, T. Sekiguchi, W. J. Hogan, R. C. Arndorfer, and D. J. Petrie. Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects. J. Clin. Invest. 65: 256-267, 1980.
4. Dodds, W. J., W. J. Hogan, J. F. Helm, and J. Dent. Pathogenesis of reflux esophagitis. Gastroenterology 81: 376-394, 1981.
5. Holloway, R. H., and J. Dent. Pathophysiology of gastroesophageal reflux. Gastroenterol. Clin. North Am. 19: 517-535, 1990.
6. Holloway, R. H., M. Hongo, K. Berger, and R. W. McCallum. Gastric distention: a mechanism for postprandial gastroesophageal reflux. Gastroenterology 89: 779-784, 1985.
7. Martin, C. J., W. J. Dodds, H. H. Liem, R. O. Dantas, R. D. Layman, and J. Dent. Diaphragmatic contribution to gastroesophageal competence and reflux in dogs. Am. J. Physiol. 263 (Gastrointest. Liver Physiol. 26): G551-G557, 1992.
8. Medda, B. K., I. M. Lang, R. Layman, W. J. Hogan, W. J. Dodds, and R. Shaker. Characterization and quantification of a pharyngo-UES reflex in the cat. Am. J. Physiol. 267 (Gastrointest. Liver Physiol. 30): G972-G983, 1994.
9. Mittal, R. K., C. Chiareli, J. Liu, and R. Shaker. Characteristics of lower esophageal sphincter relaxation induced by pharyngeal stimulation with minute amounts of water. Gastroenterology 111: 378-384, 1996.
10. Mittal, R. K., M. Fisher, R. W. McCallum, D. F. Rochester, J. Dent, and J. Sluss. Human lower esophageal sphincter pressure response to increased intra-abdominal pressure. Am. J. Physiol. 258 (Gastrointest. Liver Physiol. 21): G624-G630, 1990.
11. Mittal, R. K., D. F. Rochester, and R. W. McCallum. Effect of the diaphragmatic contraction on lower oesophageal sphincter pressure in man. Gut 18: 1564-1568, 1987.
12. Mittal, R. K., D. F. Rochester, and R. W. McCallum. Sphincteric action of the diaphragm during a relaxed lower esophageal sphincter in humans. Am. J. Physiol. 256 (Gastrointest. Liver Physiol. 19): G139-G144, 1989.
13. Pettersson, G. B., C. T. Bombeck, and L. M. Nyhus. The lower esophageal sphincter: mechanisms of opening and closure. Surgery 88: 307-314, 1980.
14. Richardson, B. J., and R. W. Welch. Differential effect of atropine on rightward and leftward lower esophageal sphincter pressure. Gastroenterology 81: 85-89, 1981.
15. Saeian, K., R. Shaker, P. Sharma, A. Trifan, J. Ren, Z. Sui, and K. Dua. Effect of aging on the lower esophageal sphincter pressure (LESP) response to pharyngeal water stimulation (Abstract). Gastroenterology 106: A631, 1994.
16. Shaker, R. Unsedated transnasal pharyngoesophagogastroduodenoscopy (T-PEGD). Gastrointest. Endosc. 40: 346-348, 1994.
17. Shaker, R., W. J. Dodds, P. J. Kahrilas, J. F. Helm, and W. J. Hogan. Relationship of intraluminal pH and pressure within the lower esophageal sphincter. Am. J. Gastroenterol. 86: 812-816, 1991.
18. Trifan, A., J. Ren, R. C. Arndorfer, C. Hofmann, E. Bardan, and R. Shaker. Inhibition of progressing esophageal peristalsis by pharyngeal water stimulation in humans. Gastroenterology 110: 419-423, 1996.
19. Trifan, A., R. Shaker, J. Ren, R. K. Mittal, K. Saeian, K. Dua, and M. Kusano. Inhibition of resting lower esophageal sphincter pressure by pharyngeal water stimulation in humans. Gastroenterology 108: 441-446, 1995.
20. Zaninotto, G., T. R. DeMeester, W. Schwizer, K.-E. Johansson, and S.-C. Cheng. The lower esophageal sphincter in health and disease. Am. J. Surg. 155: 104-111, 1988.