Effects of whey protein on calcium and bone metabolism in ovariectomized rats

Journal of Nutritional Science and Vitaminology

Volumn 43, Issue 2, 1997, Pages 199-210

  Takada, Yukihiro ^a   Kobayashi, Naomichi ^a   Kato, Ken ^a   Matsuyama, Hiroaki ^a   Yahiro, Masatoshi ^a   Aoe, Seiichiro ^a  

^a SNOW BRAND MILK PRODUCTS CO LTD   (Japan)

Author keywords

bone metabolism; bone mineral; bone protein; breaking force; calcium balance; calcium metabolism; hydroxyproline; milk; ovariectomized (OVX) rats; whey protein

Indexed keywords

COLLAGEN; HYDROXYPROLINE; MILK PROTEIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE METABOLISM; BONE MINERAL; BONE STRENGTH; CALCIUM METABOLISM; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DIET THERAPY; FEMALE; FEMUR; NONHUMAN; OVARIECTOMY; RAT; WHEY;

ANIMALIA;

EID: 0030938665     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.43.199     Document Type: Article

References (17)

1. Kanis JA, Geusens P, Christiansen C. 1991. Guidelines for clinical trials in osteoporosis. Osteoporosis Int 1: 182-188.
2. Seeman E, Cooper M, Hopper JL. 1988. Effect of early menopause on bone mass in normal women and patients with osteoporosis. Am J Med 85: 213-216.
3. Poneros-Schneier AG, Erdman JW Jr. 1982. Unavailability of calcium from sesame seeds, almond powder, whole wheat bread, spinach and nonfat dry milk in rats. J Food Sci 54: 150-153.
4. Kansal VK, Chaudhary S. 1982. Biological availability of calcium, phosphorus and magnesium from dairy products. Milchwissenschaft 37: 261-263.
5. Hiddink J, de Bore R, Romijn DJ. 1978. Removal of milk salts during ultrafiltration of whey and buttermilk. Neth Milk Dairy J 32: 80-93.
6. Rosenthal I. 1991. Conversion of milk to products. In: Milk and Dairy Products (Rosenthal I, ed), p 135-138. Verlagsgesellschaft mbH, Weinheim.
7. Glover FA. 1971. Concentration of milk by ultrafiltration and reverse osmosis. J Dairy Res 38: 373-379.
8. Skudder PJ. 1985. Evaluation of a porous silica-based ion-exchange medium for the production of protein fractions from rennet- and acid-whey. J Dairy Res 52: 167-168.
9. Ito T. 1991. Science of breast milk. New Food Ind 33(3): 73-80.
10. Takada Y, Yahiro M, Nakajima I. 1993. Effect of milk components on calcium absorption and bone metabolism. In: Characterization of Milk Component and Health (Yamauchi K, Imamura T, Morita T, eds), p. 171-185. Kouseikan, Tokyo.
11. Takada Y, Aoe S, Kumegawa M. 1996. Whey protein stimulates cell proliferation and differentiation in osteoblastic MC3T3-E1 cells. Biochem Biophys Res Commun 223: 445-449.
12. D'Amour FE, Blood FR, Belden DA. 1965. Manual for Laboratory Work in Mammalian Physiology, 3rd ed. University of Chicago Press, Chicago.
13. Ezawa I, Okada R, Nozaki Y, Ogata E. 1979. Breaking-properties and ash contents of femur of growing rats fed a low calcium diet. J Jpn Soc Nutr Food Sci 32: 329-335.
14. Goda T, Suruga K, Takase S, Ezawa I, Hosoya N. 1995. Dietary maltitol increases calcium content and breaking force of femoral bone in ovariectomized rats. J Nutr 125: 2869-2873.
15. Jiu LJ, Morikawa N, Omi N, Ezawa I. 1994. The effect of Tochubark on bone metabolism in the rat model with ovariectomized osteoporosis. J Nutr Sci Vitaminol 40: 261-273.
16. Takada Y, Suetake N, Yahiro M, Ahiko K, Nakajima I. 1990. Bioavailability of various dietary calcium compounds. Snow Brand Milk Prod Co Ltd Inst Rep 91: 75-84.
17. Goseki SM, Omi N, Yamamoto A, Oida S, Ezawa I, Sasaki S. 1996. Ovariectomy decreases osteogenetic activity in rat bone. J Nutr Sci Vitaminol 42: 55-67.