Mechanisms of pollution-induced airway disease: In vivo studies

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 52, Issue SUPPL. 38, 1997, Pages 37-44

  Peden, D B ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Asthma; Eosinophils; Inflammation; Lung function; Nitrogen dioxide; Ozone; Sulphur dioxide

Indexed keywords

ALLERGEN; NITROGEN DIOXIDE; OZONE; PROSTAGLANDIN E2; SULFUR DIOXIDE;

AIR POLLUTION; ASTHMA; BRONCHOSPASM; CONFERENCE PAPER; EOSINOPHIL; EXERCISE; HUMAN; INFLAMMATION; LUNG FUNCTION; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE;

AIR POLLUTANTS; ASTHMA; HUMANS; NITROGEN DIOXIDE; OZONE; RESPIRATORY HYPERSENSITIVITY; SULFUR DIOXIDE;

EID: 0030938017     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.1997.tb04869.x     Document Type: Article

References (64)

1. Bates DV, Hazucha MJ. The short-term effects of ozone on the human lung. US Government Printing Office 1973;93(15):507-40.
2. Hazucha MJ, Bates DV. Combined effect of ozone and sulphur dioxide on human pulmonary function. Nature 1975;257:50-1.
3. McDonnell WF, Horstman DH, Hazucha MJ et al. Pulmonary effects of ozone exposure during exercise: dose-response characteristics. J Appl Physiol: Respirat Environ Exercise Physiol 1983;54(5):1345-52.
4. McDonnell WF, Kehrl HR, Abdul Salaam S et al. Respiratory response of humans exposed to low levels of ozone for 6.6 hours. Arch Environ Health 1991;46:145-50.
5. Kulle TJ, Sauder LR, Hebel JR et al. Ozone response relationships in healthy nonsmokers. Am Rev Respir Dis 1985;132:36-41.
6. Linn WS, Avol EL, Shamoo DA et al. A dose-response study of healthy, heavily exercising men exposed to ozone at concentrations near the ambient air quality standard. Toxicol Ind Health 1986;2(1):99-112.
7. Beckett WS, McDonnell WF, Horstman DH et al. Role of the parasympathetic nervous system in acute lung response to ozone. J Appl Physiol: Respirat Environ Exercise Physiol 1985;59:1879-85.
8. Koren HS, Devlin RB, Becker S et al. Time-dependent changes of markers associated with inflammation in the lungs of humans exposed to ambient levels of ozone. Toxicol Pathol 1991;19(4):406-11.
9. Ying RL, Gross KB, Terzo TS et al. Indomethacin does not inhibit the ozone-induced increase in bronchial responsiveness in human subjects. Am Rev Respir Dis 1990; 142:817-21.
10. Schelegle ES, Adams WC, Siefkin AD. Indomethacin pretreatment reduces ozone-induced pulmonary function decrements in human subjects. Am Rev Respir Dis 1987; 136:1350-4.
11. Eschenbacher WL, Ying RL, Kreit JW et al. Ozone-induced lung function changes in normal and asthmatic subjects and the effect of indomethacin. Atmos Ozone Res Policy Implic 1989;493-9.
12. Hazucha MJ, Madden MC, Pape C et al. Effects of cyclo-oxygenase inhibition on ozone-induced respiratory inflammation a::d lung function changes. Eur J Physiol Occup Med 1995 (in press).
13. Folinsbee LJ. Human health effects of air pollution. Environ Health Perspect 1993;100:45-56.
14. Passannante A, Hazucha MJ, Seal E et al. Nociceptive mechanisms modulate ozone-induced human lung function decrements [Abstract]. Anesth Analg 1995;80:S371.
15. Krishna M, Springall D, Meng QH et al. Effects of 0.2 ppm ozone on the sensory nerves in the bronchial mucosa of healthy humans [Abstract]. Am J Respir Crit Care Med 1996;153(4):A700.
16. Aris RM, Christian D, Hearne PQ et al. Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy. Am Rev Respir Dis 1993; 148:1363-72.
17. Koren HS, Devlin RB, Graham DE et al. Ozone-induced inflammation in the lower airways of human subjects. Am Rev Respir Dis 1989;139:407-15.
18. Schelegle ES, Siefkin AD, McDonald RJ. Time course of ozone-induced neutrophilia in normal humans. Am Rev Respir Dis 1991;143:1353-8.
19. Devlin RB, McDonnell WF, Mann R et al. Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung. Am J Respir Cell Mol Biol 1991;4:72-81.
20. 3-induced change in bronchial reactivity to methacholine and airway inflammation in humans, J Appl Physiol 1986;60:1321-6.
21. Bottei GM. Devlin RB, Bromberg PA et al. The effect of corticosteroids on lower airway inflammation and pulmonary function after ozone exposure [Abstract]. Am J Respir Crit Care Med 1995;151:A29.
22. McKinnon KP, Noah T, Madden M et al. Cultured human bronchial epithelial cells release cytokines, fibronectin, and lipids in response to ozone exposure. Chest 1992;101:22S.
23. McKinnon KP, Madden MC, Noah TL et al. In vitro ozone exposure increases release of arachidonic acid products from a human bronchial epithelial cell line. Toxicol Appl Pharmacol 1993;118:215-23.
24. Beck NB, Koenig JQ, Luchtel DL et al. Ozone can increase the expression of intercellular adhesion molecule-1 and the synthesis of cytokines by human nasal epithelial cells. Inhal Toxicol 1994;6:345-57.
25. Balmes JR. The role of ozone exposure in the epidemiology of asthma. Environ Health Perspect 1993;101:219-24.
26. Bates DV, Sizto R. Relationship between air pollutant levels and hospital admissions in Southern Ontario. Can J Public Health 1983;74:117-22.
27. Silverman F. Asthma and respiratory irritants (ozone). Environ Health Perspect 1979;29:131-6.
28. Kreit JW, Gross KB, Moore TB et al. Ozone-induced changes in pulmonary function and bronchial responsiveness in asthmatics. J Appl Physiol: Respirat Environ Exercise Physiol 1989;66:217-22.
29. 3) [Abstract]. Am J Respir Crit Care Med 1993;147:A640.
30. 3). Physiologist 1984; 27:212.
31. Fernandes ALG, Molfino NA, McClean PA et al. The effect of pre-exposure to 0.12 ppm of ozone on exercise-induced asthma. Chest 1994;106:1077-82.
32. Weymer AR, Gong H, Lyness A et al. Pre-exposure to ozone does not enhance or produce exercise-induced asthma. Am J Respir Crit Care Med 1994;149:1413-9.
33. Bascom R, Naclerio RM, Fitzgerald TK et al. Effect of ozone inhalation on the response to nasal challenge with antigen of allergic subjects. Am Rev Respir Dis 1990; 142:594-601.
34. Basha MA, Gross KB, Gwizdala CJ et al. Bronchoalveolar lavage neutrophilia in asthmatic and healthy volunteers after controlled exposure to ozone and filtered purified air. Chest 1994;106:1757-65.
35. Scannell CH, Chen LL, Aris R et al. Greater ozone-induced inflammatory responses in subjects with asthma. Am J Respir Crit Care Med 1996;154:24-9.
36. Peden D, Boehlecke B, Horstman D, Devlin RB. Influx of bronchial neutrophils and eosinophils in asthmatics after exposure to 0.16 ppm ozone [Abstract]. Am J Respir Crit Care Med 1996;153:A700.
37. Frampton MW, Torres A, Voter KZ et al. Ozone exposure in subjects with asthma increases BAL lymphocyte number and activation [Abstract]. Am J Respir Crit Care Med 1996;153:A700.
38. Molfino NA, Wright SC, Katz I et al. Effect of low concentrations of ozone on inhaled allergen responses in asthmatic subjects. Lancet 1991;338:199-203.
39. Ball BA, Folinsbee LJ, Peden DB et al. Response to allergen bronchoprovocation of mild allergic asthmatics following low level ozone exposure [Abstract]. Am J Respir Crit Care Med 1995;151:A27.
40. Jorres R, Nowak D, Magnussen H. The effects of ozone exposure on allergen responsiveness in subjects with asthma or rhinitis. Am J Respir Crit Care Med 1996; 153(l):56-64.
41. Peden DB, Setzer RW Jr, Devlin RB. Ozone exposure has both a priming effect on allergen-induced responses and an intrinsic inflammatory action in the airways of perennially-allergic asthmatics. Am J Respir Crit Care Med 1995;151:1336-45.
42. Molfino NA. Effect of air pollution on atopic asthma. Medicina 1992;52:363-7.
43. Boushey HA. Bronchial hyperreactivity to sulphur dioxide: physiologic and political implications. J Allergy Clin Immunol 1982;69(4):335-8.
44. Witek TJ, Schachter EN. Airway responses to sulfur dioxide and methacholine in asthmatics. J Occup Med 1985;27(4):265-8.
45. Hackney JD, Linn WS, Bailey RM et al. Time course of exercise-induced bronchoconstriction in asthmatics exposed to sulfur dioxide. Environ Res 1984;34:321-7.
46. Horstman D, Roger LJ, Kehrl H et al. Airway sensitivity of asthmatics to sulfur dioxide. Toxicol Ind Health 1986;2(3):289-98.
47. Kehrl HR, Roger LJ, Hazucha MJ et al. Differing response of asthmatics to sulfur dioxide exposure with continuous and intermittent exercise. Am Rev Respir Dis 1987;135:350-5.
48. Folinsbee LJ, Bedi JF, Horvath SM. Pulmonary response to threshold levels of sulfur dioxide (1.0 ppm) and ozone (0.3 ppm). J Appl Physiol: Respirat Environ Exercise Physiol 1985;58:1783-7.
49. Roger LJ, Kehrl HR, Hazucha MJ et al. Bronchoconstriction in asthmatics exposed to sulfur dioxide during repeated exercise. J Appl Physiol: Respirat Environ Exercise Physiol 1985;59(3):784-91.
50. Horstman DH, Seal E Jr, Folinsbee LJ. The relationship between exposure duration and sulfur dioxide bronchoconstriction in asthmatic subjects. Am Ind Hyg Assoc J 1988;49(l):38-47.
51. Pierson WE, Koenig JQ. Respiratory effects of air pollution on allergic disease. J Allergy Clin Immunol 1992;90:557-66.
52. Gong H Jr. Health effects of air pollution. A review of clinical studies. Clin Chest Med 1992;13:201-14.
53. Linn WS, Shamoo DA, Spier CE et al. Respiratory effects of 0.75 ppm sulfur dioxide in exercising asthmatics: influence of upper-respiratory defenses. Environ Res 1983;30: 340-8.
54. Heath SK, Koenig JQ, Morgan MS et al. Effects of sulfur dioxide exposure on African-American and Caucasian asthmatics. Environ Res 1994;66:1-11.
55. Bigby B, Boushey H. Effects of nedocromil sodium on the bronchomotor response to sulfur dioxide in asthmatic patients. J Allergy Clin Immunol 1993;92:195-7.
56. Sandstrom T, Sternberg N, Andersson M. Cell responses in bronchoalveolar fluid after exposure to sulfur dioxide: a time response study. Am Rev Respir Dis 1989;140:1828-31.
57. Bauer MA, Utell MJ, Morrow PE et al. Inhalation of 0.30 ppm nitrogen dioxide potentiates exercise-induced bronchospasm in asthmatics. Am Rev Respir Dis 1986; 134:1203-8.
58. Linn WS, Shamoo DA, Spier CE et al. Controlled exposure of volunteers with chronic obstructive pulmonary disease to nitrogen dioxide. Arch Environ Health 1985;40(6):313-7.
59. Anto JM, Sunyer J. Nitrogen dioxide and allergic asthma: starting to clarify an obscure association. Lancet 1995; 345:402-3.
60. Sandstrom T, Stjernberg N, Eklund A et al. Inflammatory cell response in bronchoalveolar lavage fluid after nitrogen dioxide exposure of healthy subjects - a dose-response study. Eur Respir J 1991;4:332-3.
61. Devalia JL, Campbell AM, Sapsford RJ et al. Effect of nitrogen dioxide on synthesis of inflammatory cytokines expressed by human bronchial epithelial cells in vitro. Am J Respir Cell Mol Biol 1993;9:271-8.
62. Koenig JQ, Covert DS, Hanley QS et al. Prior exposure to ozone potentiates subsequent response to sulfur dioxide in adolescent asthmatic subjects. Am Rev Respir Dis 1990;141:377-80.
63. Wang JH, Devalia JL, Duddle JM, Hamilton SA, Davies RJ. Effect of six hour exposure to nitrogen dioxide on early phase nasal response to allergen challenge in patients with a history of seasonal allergic rhinitis. J Allergy Clin Immunol 1995;96:669-76.
64. Devalia JL, Rusznak C, Herdman MJ, Trigg CJ, Tarraf H, Davies RJ. Effect of nitrogen dioxide and sulphur dioxide on airway response of mild asthmatic patients to allergen inhalation. Lancet 1994;344:1668-71.