Selegiline in the treatment of behavioural disturbance in Alzheimer's disease

International Journal of Geriatric Psychiatry

Volumn 12, Issue 3, 1997, Pages 319-322

  Lawlor, Brian A ^a   Aisen, Paul S ^b   Green, Cynthia ^b   Fine, Elizabeth ^b   Schmeidler, James ^b  

^a ST JAMES S HOSPITAL   (Ireland)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Behaviour disturbance; Drug trial; Selegiline

Indexed keywords

PLACEBO; SELEGILINE;

AGED; ALZHEIMER DISEASE; ARTICLE; BEHAVIOR DISORDER; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; MALE; NONHUMAN; OUTPATIENT DEPARTMENT; RANDOMIZED CONTROLLED TRIAL; RATING SCALE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; DOUBLE-BLIND METHOD; FEMALE; GERIATRIC ASSESSMENT; HUMANS; MALE; MONOAMINE OXIDASE INHIBITORS; NEUROPSYCHOLOGICAL TESTS; PSYCHIATRIC STATUS RATING SCALES; SELEGILINE; SOCIAL BEHAVIOR DISORDERS;

EID: 0030937891     PISSN: 08856230     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1166(199703)12:3<319::AID-GPS488>3.0.CO;2-Q     Document Type: Article

References (18)

1. Baumgarten, M., Becker, R. and Gauthier, S. (1990) Validity and reliability of the dementia behavior disturbance scale. J. Am. Geriatr. Soc. 38, 221-226.
2. Devanand, D. P. (1995) Role of neuroleptics in treatment of behavioral complications. In Behavioral Complications in Alzheimer's Disease. (B. A. Lawlor, Ed.). APA Press, Washington, DC, pp. 131-151.
3. Finali, G., Piccirilli, M., Oliani, C. et al. (1991) L-deprenyl therapy improves verbal memory in amnestic Alzheimer patients. Clin. Neuropharmacol. 14, 523-536.
4. Mangoni, A., Grassi, M. P. and Frattola, L. (1991) Effects of an MAO-B inhibitor in the treatment of AD. Eur. Neurol. 3, 100-107.
5. McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D. and Stadlan, E. M. (1984) Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
6. Oreland, L. and Gottfries, C. G. (1986) Brain and brain monoamine oxidase in aging and in dementia of the Alzheimer type. Prog. Neurol. Psychopharmacol. Biol. Psychiat. 10, 533-540.
7. Overall, J. E. and Beller, S. A. (1984) The Brief Psychiatric Rating Scale in gero-psychiatric research, I: Factor structure on an inpatient unit. J. Geronotol. 39, 187-193.
8. Piccinin, G. L., Finali, G. and Piccirilli, M. (1990) Neuropsychological effects of L-deprenyl in Alzheimer's type dementia. Clin. Neuropharmacol. 13, 147-163.
9. Rabins, P., Mace, M. and Lucas, M. (1982) The impact of dementia on the family. JAMA 248, 333-335.
10. Rosen, W. G., Mohs, R. C. and Davis, K. L. (1984) A new rating scale for Alzheimer's disease. Am. J. Psychiat. 141, 1356-1364.
11. Schneider, L. S., Pollock, V. E., Zemansky, M. F. et al. (1992) A pilot study of low-dose L-deprenyl in Alzheimer's disease. J. Geriatr. Psychiat. Neurol. 4, 143-148.
12. Schneider, L. S., Sobin, P. S. and Lyness, S. A. (1992) Non-neuroleptic treatment of behavioral symptoms in Alzheimer's disease and other dementias. Psychopharmacol. Bull. 28, 71-79.
13. Sunderland, T., Alterman, I. S., Yount, D. et al. (1988) A new scale for the assessment of depressed mood in dementia subjects. Am. J. Psychiat. 145, 954-955.
14. Sunderland, T., Mueller, E. A., Cohen, R. M., Jimerson, C. C., Pickar, D. and Murphy, D. L. (1985) Tyramine pressor sensitivity changes during deprenyl treatment. Psychopharmacology 85, 432-437.
15. Swearer, J. M., Drachman, D. A., O'Donnell, B. F. et al. (1988) Troublesome and disruptive behaviors in dementia. J. Am. Geriatr. Soc. 36, 784-790.
16. Tariot, P. N., Cohen, R. M., Sunderland, T. et al. (1987a) L-deprenyl in Alzheimer's disease. Arch. Gen. Psychiat. 44, 427-433.
17. Tariot, P., Sunderland, T., Weingartner, H. et al. (1987b) Cognitive effects of L-deprenyl in Alzheimer's disease. Psychopharmacology 91, 489-495.
18. Teri, L., Larson, E. B. and Reifler, B. (1988) Behavioral disturbance in dementia of the Alzheimer type. J. Am. Geriatr. Soc. 36, 1-6.