Bone mineral density is reduced in patients with Crohn's disease but not in patients with ulcerative colitis: A population based study

Gut

Volumn 40, Issue 3, 1997, Pages 313-319

  Jahnsen, J ^a   Falch, J A ^b   Aadland, E ^a   Mowinckel, P ^c  

^a AKER UNIVERSITY HOSPITAL   (Norway)

^b Hormone Laboratory

^c Glaxo Wellcome of Norway   (Norway)

Author keywords

bone mineral density; Crohn's disease; inflammatory bowel disease; osteoporosis; ulcerative colitis

Indexed keywords

CORTICOSTEROID; SALAZOSULFAPYRIDINE;

ARTICLE; BONE DENSITY; BONE MINERAL; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; ULCERATIVE COLITIS; X RAY;

EID: 0030937446     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.40.3.313     Document Type: Article

References (32)

1. Compston JE, Judd D, Crawley EO, Evans WD, Evans C, Church HA, et al. Osteoporosis in patients with inflammatory bowel disease. Gut 1987; 28: 410-5.
2. Pigot F, Roux C, Chaussade S, Hardelin D, Pelleter O, Du, et al. Low bone mineral density in patients with inflammatory bowel disease. Dig Dis Sci 1992; 37: 1396-403.
3. Clements D, Motley RJ, Evans WD, Harries AD, Rhodes J, Coles RJ, et al. Longitudinal study of cortical bone loss in patients with inflammatory bowel disease. Scand J Gastroenterol 1992; 27: 1055-60.
4. Bernstein CN, Seeger LL, Sayre JW, Anton PA, Artinian L, Shanahan F. Decreased bone density in inflammatory bowel disease is related to corticosteroid use and not disease diagnosis. J Bone Miner Res 1995; 10: 250-6.
5. Falch JA, Meyer HE. Bone mineral density measured by dual x-ray absorptiometry. Reference values in a Norwegian population. Tidsskr Nor Laegeforen 1996; 116: 2299-302.
6. O'Neill TW, Felsenberg D, Varlow J, Cooper C, Kanis JA, Silman AJ, et al. The prevalence of vertebral deformity in European men and women: The European vertebral osteoporosis study. J Bone Miner Res 1996; 11: 1010-8.
7. Falch JA, Oftebro H, Haug E. Early postmenopausal bone loss is not associated with a decrease in circulating levels of 25-hydroxyvitanin D, or vitamin D-binding protein. J Clin Endocrinol Metab 1987; 64: 836-41.
8. Scharla SH, Minne HW, Lempert UG, Leidig G, Hauber M, Raedsch R, et al. Bone mineral density and calcium regulating hormones in patients with inflammatory bowel disease (Crohn's disease and ulcerative colitis). Exp Clin Endocrinol 1994; 102: 44-9.
9. Abitbol V, Roux C, Chaussade S, Guillemant S, Kolta S, Dougados M, et al. Metabolic bone assessment in patients with inflammatory bowel disease. Gastroenterology 1995; 108: 417-22.
10. Silvennoinen JA, Karttunen TJ, Niemela SE, Manelius JJ, Lehtola JK. A controlled study on bone mineral density in patients with inflammatory bowel disease. Gut 1995; 37: 71-6.
11. Ghosh S, Cowen S, Hannan WJ, Ferguson A. Low bone mineral density in Crohn's disease, but not in ulcerative colitis, at diagnosis [comments]. Gastroenterology 1994; 107: 1031-9.
12. Lukert BP, Raisz LG. Glucocorticoid-induced osteoporosis [review]. Rheum Dis Clin North Am 1994; 20: 629-50.
13. Adler RA, Rosen CJ. Glucocorticoids and osteoporosis [review]. Endocrinol Metab Clin North Am 1994; 23: 641-54.
14. Reid IR, Evans MC, Stapleton J. Lateral spine densitometry is a more sensitive indicator of glucocorticoid-induced bone loss. J Bone Miner Res 1992; 7: 1221-5.
15. Gennari C. Glucocorticoids and bone. In: Peck WA, ed. Bone and mineral research. Amsterdam: Elsevier Publishers BV, 1995: 213-32.
16. Reid IR, Evans MC, Wattie DJ, Ames R, Cundy TF. Bone mineral density of the proximal femur and lumbar spine in glucocorticoid-treated asthmatic patients. Osteoporos Int 1992; 2: 103-5.
17. Motley RJ, Crawley EO, Evans C, Rhodes J, Compston JE. Increased rate of spinal trabecular bone loss in patients with inflammatory bowel disease. Gut 1988; 29: 1332-6.
18. Roux C, Abitbol V, Chaussade S, Kolta S, Guillemant S, Dougados M, et al. Bone loss in patients with inflammatory bowel disease: a prospective study. Osteoporos Int 1995; 5: 156-60.
19. Nielsen HK, Charles P, Mosekilde L. The effect of single oral doses of prednisone on the circadian rhythm of serum osteocalcin in normal subjects. J Clin Endocrinol Metab 1988; 67: 1025-30.
20. Poulijoki H, Liippo K, Herrala J, Salmi J, Tala E. Inhaled beclomethasone decreases serum osteocalcin in postmenopausal asthmatic women. Bone 1992; 13: 285-8.
21. MacDonald BR, Gowen M. Cytokines and bone [review]. Br J Rheumatol 1992; 31: 149-55.
22. Bjarnason I, Macpherson A, Buxton-Thomas M, Forgacs I, Moniz C. High prevalence of osteoporosis in patients with inflammatory bowel disease and low lifetime intake of corticosteroids [abstract]. Gastroenterology 1993; 105: A541.
23. Vogelsang H, Ferenci P, Woloszczuk W, Resch H, Herold C, Frotz S, et al. Bone disease in vitamin D-deficient patients with Crohn's disease. Dig Dis Sci 1989; 34: 1094-9.
24. Tromm A, Rickels K, Huppe D, Wiebe V, May B. Osteopenia in chronic inflammatory bowel diseases. Results of a cross-sectional study using quantitative computerized tomography, Leber Magen Darm 1994; 24: 23-6. [In German.]
25. Edelstein SL, Barrett CE. Relation between body size and bone mineral density in elderly men and women. Am J Epidemiol 1993; 138: 160-9.
26. Felson DT, Zhang Y, Hannan MT, Anderson JJ. Effects of weight and body mass index on bone mineral density in men and women: the Framingham study. J Bone Miner Res 1993; 8: 567-73.
27. Ruegsegger P, Medici TC, Anliker M. Corticosteroid-induced bone loss. A longitudinal study of alternate day therapy in patients with bronchial asthma using quantitative computed tomography. Eur J Clin Pharmacol 1983; 25: 615-20.
28. Clements D, Compston JE, Evans WD, Rhodes J. Hormone replacement therapy prevents bone loss in patients with inflammatory bowel disease. Gut 1993; 34: 1543-6.
29. Hui SL, Slemenda CW, Johnston CJ. Baseline measurement of bone mass predicts fracture in white women. Ann Intern Med 1989; 111: 355-61.
30. Cummings SR, Black DM, Nevitt MC, Browner WS, Cauley JA, Genant HK, et al. Appendicular bone density and age predict hip fracture in women. The Study of Osteoporotic Fractures Research Group [comments]. JAMA 1990; 263: 665-8.
31. Ross PD, Davis JW, Epstein RS, Wasnich RD. Pre-existing fractures and bone mass predict vertebral fracture incidence in women. Ann Intern Med 1991; 114: 919-23.
32. Cummings SR, Black DM, Nevitt MC, Browner W, Cauley J, Ensrud K, et al. Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group [comments]. Lancet 1993; 341: 72-5.