Aging and drug interactions. III. Individual and combined effects of cimetidine and ciprofloxacin on theophylline metabolism in healthy male and female nonsmokers

Journal of Pharmacology and Experimental Therapeutics

Volumn 280, Issue 2, 1997, Pages 627-637

  Loi, Cho Ming ^a,e   Parker, Beverly M ^a,b,c   Cusack, Barry J ^a,b,c   Vestal, Robert E ^a,b,c,d  

^a Boise VA Medical Center   (United States)

^b St Luke's Mountain States Tumor Institute   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIMETIDINE; CIPROFLOXACIN; THEOPHYLLINE;

ADULT; AGED; AGING; AREA UNDER THE CURVE; ARTICLE; COMBINATION CHEMOTHERAPY; DEMETHYLATION; DOSE RESPONSE; DRUG CLEARANCE; DRUG CROSS REACTIVITY; DRUG METABOLISM; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; HYDROXYLATION; INHIBITION KINETICS; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SMOKING;

ADULT; AGE FACTORS; AGED; AGING; ANALYSIS OF VARIANCE; BIOTRANSFORMATION; CIMETIDINE; CIPROFLOXACIN; CREATININE; DRUG INTERACTIONS; FEMALE; HUMANS; MALE; METABOLIC CLEARANCE RATE; REGRESSION ANALYSIS; SEX CHARACTERISTICS; THEOPHYLLINE;

EID: 0030937110     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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