Serpins inhibit the toxicity of amyloid peptides

European Journal of Neuroscience

Volumn 9, Issue 4, 1997, Pages 770-777

  Schubert, David ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Alzheimer's disease; Cell culture; Protease inhibitors

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; AMYLOID; SERINE PROTEINASE INHIBITOR;

ARTICLE; BRAIN CELL; CELL LINE; CYTOTOXICITY; NERVE CELL CULTURE; PRIORITY JOURNAL;

EID: 0030936558     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01425.x     Document Type: Article

References (3)

1. 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell, 52, 487-501.
2. 1-antichymotrypsin is associated solely with amyloid deposits containing the β-protein and is localized in specific cells of both normal and diseased brain. Neurobiol. Aging, 11, 123-129.
3. Behl, C., Davis, J., Cole, G. M. and Schubert, D. (1992) Vitamin E protects nerve cells from amyloid β protein toxicity. Biochem. Biophys. Res. Commun., 186, 944-950.