The early and late phases of ischemic preconditioning: A comparative analysis of their effects on infarct size, myocardial stunning, and arrhythmias in conscious pigs undergoing a 40-minute coronary occlusion

Circulation Research

Volumn 80, Issue 5, 1997, Pages 730-742

  Qiu, Yumin ^a   Tang, Xian Liang ^a   Park, Seong Wook ^a   Sun, Jiang Zhong ^a   Kalya, Anantharam ^c   Bolli, Roberto ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b University of Louisville School of Medicine   (United States)

^c NONE

Author keywords

ischemia; preconditioning; reperfusion; swine

Indexed keywords

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE BLOOD FLOW; HEART MUSCLE CONTRACTILITY; HEART MUSCLE REPERFUSION; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE TACHYCARDIA; ISCHEMIC HEART DISEASE; NONHUMAN; PRIORITY JOURNAL; STUNNED HEART MUSCLE; SWINE;

EID: 0030936283     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.80.5.730     Document Type: Article

References (48)

1. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986;74:1124-1136.
2. Jennings RB, Murry CE, Reimer KA. Preconditioning myocardium with ischemia. Cardiovasc Drugs Ther. 1991;5:933-938.
3. Downey JM. Ischemic preconditioning: nature's own cardioprotective intervention. Trends Cardiovasc Med. 1992;2:170-176.
4. Walker DM, Yellon DM. Ischaemic preconditioning: from mechanisms to exploitation. Cardiovasc Res. 1992;26:734-739.
5. Downey JM, Cohen MV, Ytrehus K, Liu Y. Cellular mechanisms in ischemic preconditioning: the role of adenosine and protein kinase C. Ann N Y Acad Sci. 1994;723:82-98.
6. Bolli R. The early and late phase of preconditioning against myocardial stunning and the essential role of oxyradicals in the late phase: an overview. Basic Res Cardiol. 1996;91:57-63.
7. Murry CE, Richard VJ, Jennings RB, Reimer KA. Myocardial protection is lost before contractile function recovers from ischemic preconditioning. Am J Physiol. 1991;260:H796-H804.
8. Van Winkle DM, Thornton JD, Downey DM, Downey JM. The natural history of preconditioning: cardioprotection depends on duration of transient ischemia and time to subsequent ischemia. Coron Artery Dis. 1991;2:613-619.
9. Burckhartt B, Yang XM, Tsuchida A, Mullane KM, Downey JM, Cohen MV. Acadesine extends the window of protection afforded by ischaemic preconditioning in conscious rabbits. Cardiovasc Res. 1995;29:653-657.
10. Marber MS, Latchman DS, Walker JM, Yellon DM. Cardiac stress protein elevation 24 h after brief ischemia or heat stress is associated with resistance to myocardial infarction. Circulation. 1993;88:1264-1272.
11. Kuzuya T, Hoshida S, Yamashita N, Fuji H, Oe H, Hori M, Kamada T, Tada M. Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia. Circ Res. 1993;72:1293-1299.
12. Sun JZ, Tang XL, Knowlton AA, Park SW, Qiu Y, Bolli R. Late preconditioning against myocardial stunning: an endogenous protective mechanism that confers resistance to postischemic dys-function 24 h after brief ischemia in conscious pigs. J Clin Invest. 1995;95:388-403.
13. Baxter GF, Marber MS, Patel VC, Yellon DM. Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning. Circulation. 1994;90:2993-3000.
14. Yang XM, Baxter GF, Yellon DM, Fletcher JR, Downey JM, Cohen MV. Second window of protection in conscious rabbits. J Mol Cell Cardiol. 1995;27:A26. Abstract.
15. Baxter GF, Goma FM, Yellon DM. Temporal characterization of the 'second window of protection': duration of the anti-infarct effect after ischemic preconditioning. Circulation. 1995;92(suppl I):I-389. Abstract.
16. Sun JZ, Tang XL, Park SW, Qiu Y, Turrens JF, Bolli R. Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs. J Clin Invest. 1996;97:562-576.
17. Tang X-L, Qiu Y, Park S-W. Sun J-Z, Park SW, Kalya A, Bolli R. Time-course of late preconditioning against myocardial stunning in conscious pigs. Circ Res. 1996;79:424-434.
18. Liu GS, Thornton J, Van Winkle DM, Stanley AWH, Olsson RA, Downey JM. Protection against infarction afforded by preconditioning is mediated by AI-adenosine receptors in the rabbit heart. Circulation. 1991;84:350-356.
19. Shiki K, Hearse DJ. Preconditioning of ischemic myocardium: reperfusion-induced arrhythmias. Am J Physiol. 1987;253:H1470-H1476.
20. Hagar JM, Hale SL, Kloner RA. Effect of preconditioning ischemia on reperfusion arrhythmias after coronary artery occlusion and reperfusion in the rat. Circ Res. 1991;68:61-68.
21. Vegh A, Komori S, Szekeres L, Parratt JR. Antiarrhythmic effects of preconditioning in anaesthetised dogs and rats. Cardiovasc Res. 1992;26:487-495.
22. Schott RJ, Rohmann S, Braun ER, Schaper W. Ischemic preconditioning reduces infarct size in swine myocardium. Circ Res. 1990;66:1133-1142.
23. Cohen MV, Liu GS, Downey JM. Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits. Circulation. 1991;84:341-349.
24. Sack S, Mohri M, Arras M, Schwarz ER, Schaper W. Ischaemic preconditioning: time course of renewal in the pig. Cardiovasc Res. 1993;27:551-5.
25. Cohen MV, Yang X-M, Downey JM. Conscious rabbits become tolerant to multiple episodes of ischemic preconditioning. Circ Res. 1994;74:998-1004.
26. Osada M, Sato T, Komori S, Tamura K. Protective effect of preconditioning on reperfusion induced ventricular arrhythmias of isolated rat hearts. Cardiovasc Res. 1991;25:441-444.
27. Tanaka M, Fujiwara H, Yamasaki K, Miyame M, Yokota R, Hasegawa K, Fujiwara F, Sasayama S. Ischemic preconditioning elevates cardiac stress protein but does not limit infarct size 24 or 48 h later in rabbits. Am J Physiol. 1994;267:H1476-H1482.
28. Jagasia D, Whiting JM, McNulty PH. Ischemic preconditioning fails to produce a second window of protection 24 hrs later in the rat. Circulation. 1996;94(suppl I):I-184. Abstract.
29. Ovize M, Kloner RA, Przyklenk K. Effect of preconditioning on regional contractile function: combined experience from three protocols. J Mol Cell Cardiol. 1992;24(suppl III):S13. Abstract.
30. Bolli R. Mechanism of myocardial 'stunning.' Circulation. 1990;82:723-738.
31. Vatner SF, Braunwald E. Cardiovascular control mechanisms in the conscious state. N Engl J Med. 1975;29:970-976.
32. Ning XH, Zweng TN, Gallagher KP. Ejection- and isovolumic contraction-phase wall thickening in nonischemic myocardium during coronary occlusion. Am J Physiol. 1990;258:H490-H499.
33. Li XY, McCay PB, Zughaib M, Jeroudi MO, Triana JF, Bolli R. Demonstration of free radical generation in the 'stunned' myocardium in the conscious dog and identification of major differences between conscious and open-chest dogs. J Clin Invest. 1993;92:1025-1041.
34. Triana JF, Li X-Y, Jamaluddin U, Thornby JI, Bolli R. Postischemic myocardial 'stunning': identification of major differences between the open-chest and the conscious dog and evaluation of the oxygen radical hypothesis in the conscious dog. Circ Res. 1991;69:731-747.
35. Bolli R, Myers ML, Zhu WX, Roberts R. Disparity of reperfusion arrhythmias after reversible myocardial ischemia in open-chest and conscious dogs. J Am Coll Cardiol. 1986;7:1047-1056.
36. Jugdutt BI. Different relations between infarct size and occluded bed size in barbiturate-anesthetized versus conscious dogs. J Am Coll Cardiol. 1985;6:1035-1046.
37. Duncker DJ, Klassen CL, Ishibashi Y, Herrlinger SH, Pavek TJ, Bache RJ. Effect of temperature on myocardial infarction in swine. Am J Physiol. 1996;270:H1189-H1199.
38. Verbinski SG, Schwartz LM, Vander Heide RS, Reimer KA. Minor variation in pericardial temperature is a major predictor of infarct size in dogs. Circulation. 1995;92(suppl I):I-457. Abstract.
39. Park SW, Tang XL, Qiu Y, Sun JZ, Bolli R. Nisoldipine attenuates myocardial stunning induced by multiple coronary occlusions in conscious pigs and this effect is independent of changes in hemo-dynamics or coronary blood flow. J Mol Cell Cardiol. 1995;28:655-666.
40. Bolli R, Zhu WX, Thornby JI, O'Neill PG, Roberts R. Time-course and determinants of recovery of function after reversible ischemia in conscious dogs. Am J Physiol. 1988;254:H102-H114.
41. Patel BS, Jeroudi MO, O'Neill PG, Bolli R. Effect of human recombinant Superoxide dismutase on canine myocardial infarction. Am J Physiol. 1990;258:H369-H380.
42. Wallenstein S, Zucker CL, Fleiss JL. Some statistical methods useful in circulation research. Circ Res. 1980;47:1-9.
43. SAS Institute Inc. SAS/STAT User's Guide, Release 6.03 Edition. Cary, NC: SAS Institute Inc; 1988.
44. Reimer KA, Murry CE, Jennings RB. Cardiac adaptation to ischemia: ischemic preconditioning increases myocardial tolerance to subsequent ischemic episodes. Circulation. 1990;82:2266-2268.
45. + channels in cardiac muscle. Nature. 1983;305:147-149.
46. Gross GJ. ATP-sensitive potassium channels and myocardial preconditioning. Basic Res Cardiol. 1995;90:85-88.
47. Kojima S, Ishikawa S, Ohsawa K, Mori H. Determination of effective and safe dose for intracoronary administration of nicorandil in dogs. Cardiovasc Res. 1990;24:727-732.
48. Qiu Y, Galin̄anes M, Hearse DJ. The protective effect of nicorandil as an additive to continuous warm cardioplegia. J Thorac Cardiovasc Surg. 1995;110:1063-1072.