Early effects of CI-924 on hepatic peroxisome proliferation, microsomal enzyme induction, PCNA, and apoptosis in B6C3F1 mice and Wistar rats

Archives of Toxicology

Volumn 71, Issue 4, 1997, Pages 250-257

  Hofstra, Angela H ^a   King, Lena M ^a   Walker, Robin M ^a  

^a PFIZER INC   (United States)

Author keywords

Apoptosis; Cell proliferation; CYP4A1; Peroxisome proliferation; Species comparison

Indexed keywords

5,5' [[1,1' BIPHENYL] 2,5 DIYLBIS(OXY)]BIS[2,2 DIMETHYLPENTANOIC ACID]; ACYL COENZYME A OXIDASE; CARNITINE ACYLTRANSFERASE; CYCLINE; PEROXISOME PROLIFERATOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME INDUCTION; FEMALE; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE;

ALKANE 1-MONOOXYGENASE; ANIMALS; ANTILIPEMIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GEMFIBROZIL; LIVER; MALE; MICE; MICROBODIES; MIXED FUNCTION OXYGENASES; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 0030935998     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050384     Document Type: Article

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