메뉴 건너뛰기




Volumn 27, Issue 2, 1997, Pages 199-222

Genetic polymorphisms in human drug-metabolizing enzymes: Potential uses of reverse genetics to identify genes of toxicological relevance

Author keywords

Cytochromes P450; Environmental genetics; Genetic variability; Risk assessment

Indexed keywords

DRUG METABOLIZING ENZYME;

EID: 0030935831     PISSN: 10408444     EISSN: None     Source Type: Journal    
DOI: 10.3109/10408449709021619     Document Type: Review
Times cited : (52)

References (243)
  • 1
    • 0027517396 scopus 로고
    • Pharmacogenetics: Its biological roots and the medical challenge
    • Kalow, W., Pharmacogenetics: its biological roots and the medical challenge, Clin. Pharmacol. Ther., 54, 235, 1993.
    • (1993) Clin. Pharmacol. Ther. , vol.54 , pp. 235
    • Kalow, W.1
  • 2
    • 0028925642 scopus 로고
    • Life of a pharmacologist or the rich life of a poor metabolizer (invited autobiographical account)
    • Kalow, W., Life of a pharmacologist or the rich life of a poor metabolizer (invited autobiographical account), Pharmacol. Toxicol., 76, 221, 1995.
    • (1995) Pharmacol. Toxicol. , vol.76 , pp. 221
    • Kalow, W.1
  • 3
    • 0026240103 scopus 로고
    • Pharmacogenetics and ecogenetics in 1991
    • Motulsky, A. G., Pharmacogenetics and ecogenetics in 1991, Pharmacogenetics, 1, 2, 1991.
    • (1991) Pharmacogenetics , vol.1 , pp. 2
    • Motulsky, A.G.1
  • 4
    • 0029000305 scopus 로고
    • Cancer genes: Single and susceptibility: exposing the difference
    • Caporaso, N. E. and Goldstein, A., Cancer genes: single and susceptibility: exposing the difference, Pharmacogenetics, 5, 59, 1995.
    • (1995) Pharmacogenetics , vol.5 , pp. 59
    • Caporaso, N.E.1    Goldstein, A.2
  • 5
    • 0023061373 scopus 로고
    • P450 genes. Structure, evolution and regulation
    • Nebert, D. W. and Gonzalez, F. J., P450 genes. Structure, evolution and regulation, Annu. Rev. Biochem., 56, 945, 1987.
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 945
    • Nebert, D.W.1    Gonzalez, F.J.2
  • 6
    • 0028007371 scopus 로고
    • Cytochrome P450: Evolution and functional diversity
    • Nebert, D. W. and McKinnon, R.A., Cytochrome P450: evolution and functional diversity, Prog. Liver Dis., 12, 63, 1994.
    • (1994) Prog. Liver Dis. , vol.12 , pp. 63
    • Nebert, D.W.1    McKinnon, R.A.2
  • 11
    • 0026209325 scopus 로고
    • Identification of genetic differences in drug metabolism: Prediction of individual risk of toxicity or cancer
    • Nebert, D. W., Identification of genetic differences in drug metabolism: prediction of individual risk of toxicity or cancer, Hepatology, 14, 398, 1991.
    • (1991) Hepatology , vol.14 , pp. 398
    • Nebert, D.W.1
  • 12
    • 0025859220 scopus 로고
    • Role of genetics and drug metabolism in human cancer risk
    • Nebert, D. W., Role of genetics and drug metabolism in human cancer risk, Mutat. Res., 247, 267, 1991.
    • (1991) Mutat. Res. , vol.247 , pp. 267
    • Nebert, D.W.1
  • 13
    • 0024829409 scopus 로고
    • The Ah locus: Genetic differences in toxicity, cancer, mutation, and birth defects
    • Nebert, D. W., The Ah locus: genetic differences in toxicity, cancer, mutation, and birth defects, Crit. Rev. Toxicol., 20, 153, 1989.
    • (1989) Crit. Rev. Toxicol. , vol.20 , pp. 153
    • Nebert, D.W.1
  • 14
    • 0026254647 scopus 로고
    • Human AH locus polymorphism and cancer: Inducibility of CYP1A1 and other genes by combustion products and dioxin
    • Nebert, D. W., Petersen, D. D., and Puga, A., Human AH locus polymorphism and cancer: inducibility of CYP1A1 and other genes by combustion products and dioxin, Pharmacogenetics, 1, 68, 1991.
    • (1991) Pharmacogenetics , vol.1 , pp. 68
    • Nebert, D.W.1    Petersen, D.D.2    Puga, A.3
  • 15
    • 0024236331 scopus 로고
    • The molecular biology of cytochrome P450s
    • Gonzalez, F. J., The molecular biology of cytochrome P450s, Pharmacol. Rev., 40, 243, 1988.
    • (1988) Pharmacol. Rev. , vol.40 , pp. 243
    • Gonzalez, F.J.1
  • 16
    • 0011899029 scopus 로고
    • The Ah receptor: A biochemical and biological perspective
    • Conn, P.M., Ed., New York, Academic Press
    • Greenlee, W. F. and Neal, R. A., The Ah receptor: a biochemical and biological perspective, inThe Receptors, Vol. 2, Conn, P.M., Ed., New York, Academic Press, 1985, 89.
    • (1985) The Receptors , vol.2 , pp. 89
    • Greenlee, W.F.1    Neal, R.A.2
  • 17
    • 0026725943 scopus 로고
    • Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor
    • Burbach, K. M., Poland, A., and Bradfield, C. A., Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor, Proc. Natl. Acad. Sci. U.S.A., 89, 8185, 1992.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 8185
    • Burbach, K.M.1    Poland, A.2    Bradfield, C.A.3
  • 19
    • 0027326075 scopus 로고
    • Research on the aryl hydrocarbon (dioxin) receptor is primed to take off
    • Hankinson, O., Research on the aryl hydrocarbon (dioxin) receptor is primed to take off, Arch. Biochem. Biophys., 300, 1, 1993.
    • (1993) Arch. Biochem. Biophys. , vol.300 , pp. 1
    • Hankinson, O.1
  • 20
    • 0027458138 scopus 로고
    • The AH-receptor: Genetics, structure and function
    • Swanson, H. I. and Bradfield, C. A., The AH-receptor: genetics, structure and function, Pharmacogenetics, 3, 213, 1993.
    • (1993) Pharmacogenetics , vol.3 , pp. 213
    • Swanson, H.I.1    Bradfield, C.A.2
  • 21
    • 0025875527 scopus 로고
    • The Ah receptor and the mechanism of dioxin toxicity
    • Landers, J. P. and Bunce, N. J., The Ah receptor and the mechanism of dioxin toxicity, Biochem. J., 276, 273, 1991.
    • (1991) Biochem. J. , vol.276 , pp. 273
    • Landers, J.P.1    Bunce, N.J.2
  • 22
    • 0027922810 scopus 로고
    • Role of the Ah receptor and dioxin inducible [Ah] gene battery in toxicity, cancer, and signal transduction
    • Nebert, D. W., Puga, A., and Vasiliou, V., Role of the Ah receptor and dioxin inducible [Ah] gene battery in toxicity, cancer, and signal transduction, Ann. N. Y. Acad. Sci., 685, 624, 1993.
    • (1993) Ann. N. Y. Acad. Sci. , vol.685 , pp. 624
    • Nebert, D.W.1    Puga, A.2    Vasiliou, V.3
  • 23
    • 0025307742 scopus 로고
    • Genetic and molecular aspects of 2,3,7,8-tetrachlorodibenzo-p-dioxin action
    • Whitlock, J. P., Jr., Genetic and molecular aspects of 2,3,7,8-tetrachlorodibenzo-p-dioxin action, Annu. Rev. Pharmacol. Toxicol., 30, 251, 1991.
    • (1991) Annu. Rev. Pharmacol. Toxicol. , vol.30 , pp. 251
    • Whitlock Jr., J.P.1
  • 24
    • 0016286436 scopus 로고
    • 1-450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically "non-responsive" to other aromatic hydrocarbons
    • 1-450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically "non-responsive" to other aromatic hydrocarbons, J. Biol. Chem., 249, 5599, 1974.
    • (1974) J. Biol. Chem. , vol.249 , pp. 5599
    • Poland, A.1    Glover, E.2    Robinson, J.R.3    Nebert, D.W.4
  • 25
    • 0027944549 scopus 로고
    • Analysis of the four alleles of the murine aryl hydrocarbon receptor
    • Poland, A., Palen, D., and Glover, E., Analysis of the four alleles of the murine aryl hydrocarbon receptor, Mol. Pharmacol., 46, 915, 1994.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 915
    • Poland, A.1    Palen, D.2    Glover, E.3
  • 26
    • 0028034621 scopus 로고
    • Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors
    • Ema, M., Ohe, N., Suzuki, M., Mimura, J., Sogawa, K., Ikawa, S., and Fujii-Kuriyama, Y., Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors, J. Biol. Chem., 269, 27337, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27337
    • Ema, M.1    Ohe, N.2    Suzuki, M.3    Mimura, J.4    Sogawa, K.5    Ikawa, S.6    Fujii-Kuriyama, Y.7
  • 27
    • 0027762492 scopus 로고
    • Ten nucleotide differences, five of which cause amino acid changes, are associated with the Ah receptor locus polymorphism of C57BL/6 and DBA/2 mice
    • Chang, C.-Y., Smith, D. R., Prasad, V. S., Sidman, C. L., Nebert, D. W., and Puga, A., Ten nucleotide differences, five of which cause amino acid changes, are associated with the Ah receptor locus polymorphism of C57BL/6 and DBA/2 mice, Pharmacogenetics, 3, 312, 1993.
    • (1993) Pharmacogenetics , vol.3 , pp. 312
    • Chang, C.-Y.1    Smith, D.R.2    Prasad, V.S.3    Sidman, C.L.4    Nebert, D.W.5    Puga, A.6
  • 29
    • 0027439096 scopus 로고
    • CYP1A1 mRNA levels as a human exposure biomarker: Use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes
    • Vanden Heuvel, J. P., Clark, G. C., Thompson, C. L., McCoy, Z., Miller, C. R., Lucier, G. W., and Bell, D. A., CYP1A1 mRNA levels as a human exposure biomarker: use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes, Carcinogenesis, 14, 2003, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 2003
    • Vanden Heuvel, J.P.1    Clark, G.C.2    Thompson, C.L.3    McCoy, Z.4    Miller, C.R.5    Lucier, G.W.6    Bell, D.A.7
  • 30
    • 0015682899 scopus 로고
    • Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma
    • Kellerman, G., Shaw, C. R., and Luyten-Kellerman, M., Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma, N. Engl. J. Med., 289, 934, 1973.
    • (1973) N. Engl. J. Med. , vol.289 , pp. 934
    • Kellerman, G.1    Shaw, C.R.2    Luyten-Kellerman, M.3
  • 32
    • 0025950875 scopus 로고
    • Cancer mortality among workers in chemical plant contaminated with dioxin
    • Manz, A., Berger, J., Dwyer, J. H., Flesch-Janys, D., Nagel, S., and Waltsgott, H., Cancer mortality among workers in chemical plant contaminated with dioxin, Lancet, 338, 959, 1991.
    • (1991) Lancet , vol.338 , pp. 959
    • Manz, A.1    Berger, J.2    Dwyer, J.H.3    Flesch-Janys, D.4    Nagel, S.5    Waltsgott, H.6
  • 33
    • 0025923744 scopus 로고
    • Long-term effects of chemical disasters. Lessons and results from Seveso
    • Bertazzi, P. A., Long-term effects of chemical disasters. Lessons and results from Seveso, Sci. Total Environ., 106, 5, 1991.
    • (1991) Sci. Total Environ. , vol.106 , pp. 5
    • Bertazzi, P.A.1
  • 34
    • 0020385021 scopus 로고
    • Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes
    • Kouri, R. E., McKinney, C. E., Slomiany, D. J., Snodgrass, D. R., Wray, N. P., and McLemore, T. L., Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes, Cancer Res., 42, 5030, 1982.
    • (1982) Cancer Res. , vol.42 , pp. 5030
    • Kouri, R.E.1    McKinney, C.E.2    Slomiany, D.J.3    Snodgrass, D.R.4    Wray, N.P.5    McLemore, T.L.6
  • 37
    • 0017804575 scopus 로고
    • Aryl hydrocarbon hydroxylase inducibility in patients with cancer
    • Emery, A. E. H., Danford, N., Anand, R., Duncam, W., and Paton, L., Aryl hydrocarbon hydroxylase inducibility in patients with cancer, Lancet, 1, 470, 1978.
    • (1978) Lancet , vol.1 , pp. 470
    • Emery, A.E.H.1    Danford, N.2    Anand, R.3    Duncam, W.4    Paton, L.5
  • 38
    • 0017814702 scopus 로고
    • Aryl hydrocarbon hydroxylase and bronchogenic carcinomas associated with smoking
    • Körsgaard, R. and Trell, E., Aryl hydrocarbon hydroxylase and bronchogenic carcinomas associated with smoking, Lancet, 1, 1103, 1978.
    • (1978) Lancet , vol.1 , pp. 1103
    • Körsgaard, R.1    Trell, E.2
  • 39
    • 8244223795 scopus 로고
    • Aryl hydrocarbon hydroxylase in normal and cancer populations
    • Griffin, A.C. and Shaw, C.R, Eds., Raven Press, New York
    • Arnott, M. S., Yamauchi, T., and Johnston, D. A., Aryl hydrocarbon hydroxylase in normal and cancer populations, in Carcinogens: Identification and Mechanisms of Action, Griffin, A.C. and Shaw, C.R, Eds., Raven Press, New York, 1979, 145.
    • (1979) Carcinogens: Identification and Mechanisms of Action , pp. 145
    • Arnott, M.S.1    Yamauchi, T.2    Johnston, D.A.3
  • 40
    • 0018341143 scopus 로고
    • Induction of aryl hydrocarbon hydroxylase activity and pulmonary carcinoma
    • Gahmberg, C. G., Sekki, A., Kosunen, T. U., Holsti, L. R., and Makela, O., Induction of aryl hydrocarbon hydroxylase activity and pulmonary carcinoma, Int. J. Cancer, 23, 302, 1979.
    • (1979) Int. J. Cancer , vol.23 , pp. 302
    • Gahmberg, C.G.1    Sekki, A.2    Kosunen, T.U.3    Holsti, L.R.4    Makela, O.5
  • 41
    • 0018578328 scopus 로고
    • Aryl hydrocarbon hydroxylase acticity in pulmonary alveolar macrophages and lymphocytes from lung cancer and noncancer patients
    • McLemore, T. L., Martin, R. R., Springer, R. R., Wray, N., Cantrell, E. T., and Busbee, D. L., Aryl hydrocarbon hydroxylase acticity in pulmonary alveolar macrophages and lymphocytes from lung cancer and noncancer patients, Biochem. Genet., 17, 795, 1979.
    • (1979) Biochem. Genet. , vol.17 , pp. 795
    • McLemore, T.L.1    Martin, R.R.2    Springer, R.R.3    Wray, N.4    Cantrell, E.T.5    Busbee, D.L.6
  • 43
    • 0018276544 scopus 로고
    • Smoking and oral carcinoma
    • Trell, E. and Körsgaard, R., Smoking and oral carcinoma, Lancet, 1, 671, 1978.
    • (1978) Lancet , vol.1 , pp. 671
    • Trell, E.1    Körsgaard, R.2
  • 46
    • 0017777776 scopus 로고
    • Aryl hydrocarbon hydroxylase inducibility in carcinoma of renal pelvis and ureter
    • Trell, E., Oldbring, J., Körsgaard, R., and Mattiasson, I., Aryl hydrocarbon hydroxylase inducibility in carcinoma of renal pelvis and ureter, Lancet, 2, 612, 1977.
    • (1977) Lancet , vol.2 , pp. 612
    • Trell, E.1    Oldbring, J.2    Körsgaard, R.3    Mattiasson, I.4
  • 48
    • 0017670495 scopus 로고
    • Factors influencing the measurement and the reproducibility of aryl hydrocarbon hydroxylase activity in cultured human lymphocytes
    • Gurtoo, H. L., Minowada, J., Paigen, B., Parker, N. B., and Hayner, N. T., Factors influencing the measurement and the reproducibility of aryl hydrocarbon hydroxylase activity in cultured human lymphocytes, J. Nat. Cancer Inst., 59, 787, 1977.
    • (1977) J. Nat. Cancer Inst. , vol.59 , pp. 787
    • Gurtoo, H.L.1    Minowada, J.2    Paigen, B.3    Parker, N.B.4    Hayner, N.T.5
  • 49
    • 0017880026 scopus 로고
    • Benzo[a]pyrene metabolism and blast formation in peripheral blood mononuclear cells from smoking and non-smoking populations and lung cancer patients
    • Jett, J. R., Moses, H. L., Branum, E. L., Taylor, W. F., and Fontana, R. S., Benzo[a]pyrene metabolism and blast formation in peripheral blood mononuclear cells from smoking and non-smoking populations and lung cancer patients, Cancer, 41, 192, 1978.
    • (1978) Cancer , vol.41 , pp. 192
    • Jett, J.R.1    Moses, H.L.2    Branum, E.L.3    Taylor, W.F.4    Fontana, R.S.5
  • 50
    • 0018275337 scopus 로고
    • Aryl hydrocarbon hydroxylase in bronchogenic carcinoma
    • Lieberman, J., Aryl hydrocarbon hydroxylase in bronchogenic carcinoma, N. Engl. J. Med., 298, 686, 1978.
    • (1978) N. Engl. J. Med. , vol.298 , pp. 686
    • Lieberman, J.1
  • 55
    • 0027997383 scopus 로고
    • Characterization of Ah receptor promoter in human liver cell line, HepG2
    • Takahashi, Y., Itoh, S., Shimojima, T., and Kamataki, T., Characterization of Ah receptor promoter in human liver cell line, HepG2, Pharmacogenetics, 4, 219, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 219
    • Takahashi, Y.1    Itoh, S.2    Shimojima, T.3    Kamataki, T.4
  • 56
    • 0029020636 scopus 로고
    • Polymorphic forms of the Ah receptor and induction of the CYP1A1 gene
    • Fujii-Kuriyama, Y., Ema, M., Matsushita, N., and Sogawa, K., Polymorphic forms of the Ah receptor and induction of the CYP1A1 gene, Pharmacogenetics, 5, S149, 1995.
    • (1995) Pharmacogenetics , vol.5
    • Fujii-Kuriyama, Y.1    Ema, M.2    Matsushita, N.3    Sogawa, K.4
  • 60
    • 0025236927 scopus 로고
    • Identification of genetically high risk individuals to lung cancer by polymorphisms of the cytochrome P450IA1 gene
    • Kawajiri, K., Nakachi, K., Imai, K., Yoshii, A., Shinoda, N., and Watanabe, J., Identification of genetically high risk individuals to lung cancer by polymorphisms of the cytochrome P450IA1 gene, FEBS Lett., 263, 131, 1990.
    • (1990) FEBS Lett. , vol.263 , pp. 131
    • Kawajiri, K.1    Nakachi, K.2    Imai, K.3    Yoshii, A.4    Shinoda, N.5    Watanabe, J.6
  • 61
    • 0025914145 scopus 로고
    • Genetic linkage of lung cancer-associates Msp I polymorphisms with amino acid replacement in the heme-binding region of the human cytochrome P450IA1 gene
    • Tokyo
    • Hayashi, S.-I., Watanabe, J., Nakachi, K., and Kawajiri, K., Genetic linkage of lung cancer-associates Msp I polymorphisms with amino acid replacement in the heme-binding region of the human cytochrome P450IA1 gene, J. Biochem. (Tokyo), 110, 407, 1991.
    • (1991) J. Biochem. , vol.110 , pp. 407
    • Hayashi, S.-I.1    Watanabe, J.2    Nakachi, K.3    Kawajiri, K.4
  • 62
    • 0025737529 scopus 로고
    • PCR detection of an A/G polymorphism within exon 7 of the CYP1A1 gene
    • Hayashi, S.-I., Watanabe, J., Nakachi, K., and Kawajiri, K., PCR detection of an A/G polymorphism within exon 7 of the CYP1A1 gene, Nucleic Acids Res., 19, 4797, 1991.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 4797
    • Hayashi, S.-I.1    Watanabe, J.2    Nakachi, K.3    Kawajiri, K.4
  • 63
    • 0026785516 scopus 로고
    • High susceptibility to lung cancer analyzed in terms of combined genotypes of P450IA1 and Mu-class glutathione S-transferase genes
    • Hayashi, S., Watanabe, J., and Kawajiri, K., High susceptibility to lung cancer analyzed in terms of combined genotypes of P450IA1 and Mu-class glutathione S-transferase genes, Jpn. J. Cancer Res., 83, 866, 1992.
    • (1992) Jpn. J. Cancer Res. , vol.83 , pp. 866
    • Hayashi, S.1    Watanabe, J.2    Kawajiri, K.3
  • 64
    • 0027304210 scopus 로고
    • Polymorphisms of the CYP1A1 and glutathione S-transterase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population
    • Nakachi, K., Imai, K., Hayashi, S., and Kawajiri, K., Polymorphisms of the CYP1A1 and glutathione S-transterase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population, Cancer Res., 53, 2994, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 2994
    • Nakachi, K.1    Imai, K.2    Hayashi, S.3    Kawajiri, K.4
  • 66
    • 0027220611 scopus 로고
    • Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes
    • Shields, P. G., Bowman, E. D., Harrington, A. M., Doan, V. T., and Weston, A., Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes, Cancer Res., 53, 3486, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 3486
    • Shields, P.G.1    Bowman, E.D.2    Harrington, A.M.3    Doan, V.T.4    Weston, A.5
  • 67
    • 0026921501 scopus 로고
    • Point-mutational MspI and Ile-Val polymorphisms closely linked in the CYP1A1 gene: Lack of association with susceptibility to lung cancer in a Finnish study population
    • Hirvonen, A., Husgafvel-Pursiainen, K., Karjalainen, A., Anttila, S., and Vainio, H., Point-mutational MspI and Ile-Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population, Cancer Epidemiol. Biomark. Prev., 1, 485, 1992.
    • (1992) Cancer Epidemiol. Biomark. Prev. , vol.1 , pp. 485
    • Hirvonen, A.1    Husgafvel-Pursiainen, K.2    Karjalainen, A.3    Anttila, S.4    Vainio, H.5
  • 69
    • 0028182661 scopus 로고
    • 1462V mutation in the human CYP1A1 gene: Lack of correlation with either the Msp I 1.9 kb (M2) allele or CYP1A1 inducibility in a three-generation family of east Mediterranean descent
    • Wedlund, P. J., Kimura, S., Gonzalez, F. J., and Nebert, D. W., 1462V mutation in the human CYP1A1 gene: lack of correlation with either the Msp I 1.9 kb (M2) allele or CYP1A1 inducibility in a three-generation family of east Mediterranean descent, Pharmacogenetics, 4, 21, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 21
    • Wedlund, P.J.1    Kimura, S.2    Gonzalez, F.J.3    Nebert, D.W.4
  • 71
    • 0028919248 scopus 로고
    • A specific African-American CYP1A1 polymorphism is associated with adenocarcinoma of the lung
    • Taioli, E., Crofts, F., Trachman, J., Demopoulos, R., Toniolo, P., and Garte, S. J., A specific African-American CYP1A1 polymorphism is associated with adenocarcinoma of the lung, Cancer Res., 55, 472, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 472
    • Taioli, E.1    Crofts, F.2    Trachman, J.3    Demopoulos, R.4    Toniolo, P.5    Garte, S.J.6
  • 72
    • 0028225363 scopus 로고
    • A race-specific genetic polymorphism in the CYP1A1 gene is not associated with lung cancer in African-Americans
    • Kelsey, K. T., Wiencke, J. K., and Spitz, M. R., A race-specific genetic polymorphism in the CYP1A1 gene is not associated with lung cancer in African-Americans, Carcinogenesis, 15, 1121, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1121
    • Kelsey, K.T.1    Wiencke, J.K.2    Spitz, M.R.3
  • 74
    • 0029097694 scopus 로고
    • A CYP1A1 restriction fragment length polymorphism is associated with breast cancer in African-American women
    • Taioli, E., Trachman, J., Chen, X., Toniolo, P., and Garte, S. J., A CYP1A1 restriction fragment length polymorphism is associated with breast cancer in African-American women, Cancer Res., 55, 3757, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3757
    • Taioli, E.1    Trachman, J.2    Chen, X.3    Toniolo, P.4    Garte, S.J.5
  • 76
    • 0025940815 scopus 로고
    • Molecular genetics of the debrisoquine-sparteine polymorphism
    • Gonzalez, F. J. and Meyer, U. A., Molecular genetics of the debrisoquine-sparteine polymorphism, Clin. Pharmacol. Ther., 50, 233, 1991.
    • (1991) Clin. Pharmacol. Ther. , vol.50 , pp. 233
    • Gonzalez, F.J.1    Meyer, U.A.2
  • 77
    • 0027965620 scopus 로고
    • Genetic analysis of the Chinese cytochrome P4502D locus: Characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation
    • Johansson, I., Oscarson, M., Yue, Q.-Y., Bertilsson, L., Sjöqvist, F., and Ingelman-Sundberg, M., Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation, Mol. Pharmacol., 46, 452, 1994.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 452
    • Johansson, I.1    Oscarson, M.2    Yue, Q.-Y.3    Bertilsson, L.4    Sjöqvist, F.5    Ingelman-Sundberg, M.6
  • 80
    • 0026817161 scopus 로고
    • Clinical implications of variable antiarrhythmic drug metabolism
    • Buchert, E. T. and Woosley, R. L., Clinical implications of variable antiarrhythmic drug metabolism, Pharmacogenetics, 2, 2, 1992.
    • (1992) Pharmacogenetics , vol.2 , pp. 2
    • Buchert, E.T.1    Woosley, R.L.2
  • 81
    • 0026033923 scopus 로고
    • Polymorphism of human CYP2D genes involved in drug metabolism: Possible relationship to individual cancer risk
    • Nebert, D. W., Polymorphism of human CYP2D genes involved in drug metabolism: possible relationship to individual cancer risk, Cancer Cells, 3, 93, 1991.
    • (1991) Cancer Cells , vol.3 , pp. 93
    • Nebert, D.W.1
  • 82
    • 0027983085 scopus 로고
    • Pharmacogenetic phenotyping and genotyping: Present status and future potential
    • Gonzalez, F. J. and Idle, J. R., Pharmacogenetic phenotyping and genotyping: present status and future potential, Clin. Pharmacokinet., 26, 59, 1994.
    • (1994) Clin. Pharmacokinet. , vol.26 , pp. 59
    • Gonzalez, F.J.1    Idle, J.R.2
  • 83
    • 0029015664 scopus 로고
    • Lung cancer and CYP2D6 (the debrisoquine polymorphism): Sources of heterogeneity in the proposed association
    • Caporaso, N., DeBaun, M. R., and Rothman, N., Lung cancer and CYP2D6 (the debrisoquine polymorphism): sources of heterogeneity in the proposed association, Pharmacogenetics, 5, S129, 1995.
    • (1995) Pharmacogenetics , vol.5
    • Caporaso, N.1    DeBaun, M.R.2    Rothman, N.3
  • 85
    • 0028208792 scopus 로고
    • Pharmacogenetics: The slow, the rapid and the ultrarapid
    • Meyer, U. A., Pharmacogenetics: the slow, the rapid and the ultrarapid, Proc. Natl. Acad. Sci. U.S.A., 91, 1983, 1994.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 1983
    • Meyer, U.A.1
  • 86
    • 0022408175 scopus 로고
    • Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine
    • Barbeau, A. E., Cloutier, T., Roy, M., Plasse, L., Paris, S., and Poirier, J., Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine, Lancet, 2, 1213, 1985.
    • (1985) Lancet , vol.2 , pp. 1213
    • Barbeau, A.E.1    Cloutier, T.2    Roy, M.3    Plasse, L.4    Paris, S.5    Poirier, J.6
  • 87
    • 0023279624 scopus 로고
    • Debrisoquine metabolism in Parkinsonian patients treated with antihistamine drugs
    • Poirier, J., Roy, M., Campanella, G., Cloutier, T., and Paris, S., Debrisoquine metabolism in Parkinsonian patients treated with antihistamine drugs, Lancet, 2, 386, 1987.
    • (1987) Lancet , vol.2 , pp. 386
    • Poirier, J.1    Roy, M.2    Campanella, G.3    Cloutier, T.4    Paris, S.5
  • 90
    • 0025307264 scopus 로고
    • Poor hydroxylator phenotypes of debrisoquine are not overrepresented in a group of patients with Parkinson's disease
    • Gudjonsson, O., Sanz, E., Alvan, G., Aquilonius, S.-M., and Reviriego, J., Poor hydroxylator phenotypes of debrisoquine are not overrepresented in a group of patients with Parkinson's disease, Br. J. Clin. Pharmacol., 30, 301, 1990.
    • (1990) Br. J. Clin. Pharmacol. , vol.30 , pp. 301
    • Gudjonsson, O.1    Sanz, E.2    Alvan, G.3    Aquilonius, S.-M.4    Reviriego, J.5
  • 92
    • 0027348840 scopus 로고
    • Debrisoquine hydroxylase and Parkinson's disease
    • Kondo, I. and Kanazawa, I., Debrisoquine hydroxylase and Parkinson's disease, Adv. Neurol., 60, 338, 1993.
    • (1993) Adv. Neurol. , vol.60 , pp. 338
    • Kondo, I.1    Kanazawa, I.2
  • 93
    • 0026589459 scopus 로고
    • Mutant debrisoquine hydroxylation genes in Parkinson's disease
    • Armstrong, M., Daly, A. K., Cholerton, S., Bateman, D. N., and Idle, J. R., Mutant debrisoquine hydroxylation genes in Parkinson's disease, Lancet, 339, 1017, 1992.
    • (1992) Lancet , vol.339 , pp. 1017
    • Armstrong, M.1    Daly, A.K.2    Cholerton, S.3    Bateman, D.N.4    Idle, J.R.5
  • 95
    • 0025779409 scopus 로고
    • Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): Potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6
    • Tyndale, R. F., Sunahara, R., Inaba, T., Kalow, W., Gonzalez, F. J., and Niznik, H. B., Neuronal cytochrome P450IID1 (debrisoquine/sparteine-type): potent inhibition of activity by (-)-cocaine and nucleotide sequence identity to human hepatic P450 gene CYP2D6, Mol. Pharmacol., 40, 63, 1991.
    • (1991) Mol. Pharmacol. , vol.40 , pp. 63
    • Tyndale, R.F.1    Sunahara, R.2    Inaba, T.3    Kalow, W.4    Gonzalez, F.J.5    Niznik, H.B.6
  • 96
    • 0027319640 scopus 로고
    • Are poor metabolisers of sparteine/debrisoquine less pain tolerant than extensive metabolisers?
    • Sindrup, S. H., Poulsen, L., Brosen, K., Arendt-Nielsen, L., and Gram, L. F., Are poor metabolisers of sparteine/debrisoquine less pain tolerant than extensive metabolisers?, Pain, 53, 335, 1993.
    • (1993) Pain , vol.53 , pp. 335
    • Sindrup, S.H.1    Poulsen, L.2    Brosen, K.3    Arendt-Nielsen, L.4    Gram, L.F.5
  • 97
    • 0029622428 scopus 로고
    • The pharmacogenetics of codeine hypoalgesia
    • Sindrup, S. H. and Brosen, K., The pharmacogenetics of codeine hypoalgesia, Pharmacogenetics, 5, 335, 1995.
    • (1995) Pharmacogenetics , vol.5 , pp. 335
    • Sindrup, S.H.1    Brosen, K.2
  • 98
    • 0021130765 scopus 로고
    • Metabolic oxidation phenotypes are markers for susceptibility to lung cancer
    • Ayesh, R., Idle, J. R., Ritchie, J. C., Crothers, M. J., and Hetzel, M. R., Metabolic oxidation phenotypes are markers for susceptibility to lung cancer, Nature, (London), 312, 169, 1984.
    • (1984) Nature, (London) , vol.312 , pp. 169
    • Ayesh, R.1    Idle, J.R.2    Ritchie, J.C.3    Crothers, M.J.4    Hetzel, M.R.5
  • 99
    • 0002006730 scopus 로고
    • Polymorphic enzymes and cancer risk: Concepts, methodology and data review
    • Kalow, W., Ed., Pergamon Press, New York
    • Roots, I., Drakoulis, N., and Brockmoller, J., Polymorphic enzymes and cancer risk: concepts, methodology and data review, in Pharmacogenetics of Drug Metabolism, Kalow, W., Ed., Pergamon Press, New York, 1992, 815.
    • (1992) Pharmacogenetics of Drug Metabolism , pp. 815
    • Roots, I.1    Drakoulis, N.2    Brockmoller, J.3
  • 103
    • 0026567713 scopus 로고
    • Oxidative and reductive metabolism by cytochrome P450 2E1
    • Koop, D. R., Oxidative and reductive metabolism by cytochrome P450 2E1, FASEB J., 6, 724, 1992.
    • (1992) FASEB J. , vol.6 , pp. 724
    • Koop, D.R.1
  • 104
    • 0028207549 scopus 로고
    • Cytochrome P450-dependent metabolism of acetaminophen in four human transgenic lymphoblastoid cell lines
    • Snawder, J. E., Roe, A. L., Benson, R. W., Casciano, D. A., and Roberts, D. W., Cytochrome P450-dependent metabolism of acetaminophen in four human transgenic lymphoblastoid cell lines, Pharmacogenetics, 4, 43, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 43
    • Snawder, J.E.1    Roe, A.L.2    Benson, R.W.3    Casciano, D.A.4    Roberts, D.W.5
  • 105
    • 0026035519 scopus 로고
    • Role of human P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
    • Guengerich, F. P., Kim, D.-H., and Iwasaki, M., Role of human P-450 IIE1 in the oxidation of many low molecular weight cancer suspects, Chem. Res. Toxicol., 4, 168, 1991.
    • (1991) Chem. Res. Toxicol. , vol.4 , pp. 168
    • Guengerich, F.P.1    Kim, D.-H.2    Iwasaki, M.3
  • 106
    • 0024500321 scopus 로고
    • Polymorphism of cytochrome P-450 in humans
    • Guengerich, F. P., Polymorphism of cytochrome P-450 in humans, Trends Pharmacol. Sci., 10, 107, 1989.
    • (1989) Trends Pharmacol. Sci. , vol.10 , pp. 107
    • Guengerich, F.P.1
  • 107
    • 0028568658 scopus 로고
    • Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility
    • Daly, A. K., Cholerton, S., Armstrong, M., and Idle, J. R., Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility, Environ. Health Perspect., 102 (Suppl. 9), 55, 1994.
    • (1994) Environ. Health Perspect. , vol.102 , Issue.9 SUPPL. , pp. 55
    • Daly, A.K.1    Cholerton, S.2    Armstrong, M.3    Idle, J.R.4
  • 108
    • 18344405507 scopus 로고
    • Taq I polymorphism in the human P450IIE1 gene on chromosome 10 (CYP2E)
    • McBride, O. W., Umeno, M., Gelboin, H. V., and Gonzalez, F. J., Taq I polymorphism in the human P450IIE1 gene on chromosome 10 (CYP2E), Nucleic Acids Res., 15, 10071, 1987.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 10071
    • McBride, O.W.1    Umeno, M.2    Gelboin, H.V.3    Gonzalez, F.J.4
  • 110
    • 0026062622 scopus 로고
    • Ge netic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene
    • Hayashi, S., Watanabe, J., and Kawajiri, K., Ge netic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene, J. Biochem., 110, 559, 1991.
    • (1991) J. Biochem. , vol.110 , pp. 559
    • Hayashi, S.1    Watanabe, J.2    Kawajiri, K.3
  • 112
    • 0028024393 scopus 로고
    • Ethnic variation in the CYP2E1 gene: Polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese
    • Stephens, E. A., Taylor, J. A., Kaplan, N., Yang, C.-H., Hsieh, L. L., Lucier, G. W., and Bell, D. A., Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese, Pharmacogenetics, 4, 185, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 185
    • Stephens, E.A.1    Taylor, J.A.2    Kaplan, N.3    Yang, C.-H.4    Hsieh, L.L.5    Lucier, G.W.6    Bell, D.A.7
  • 113
    • 0026069613 scopus 로고
    • Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer
    • Uematsu, F., Kikuchi, H., Motomiya, M., Abe, T., Sagami, I., Ohmachi, T., Wakui, A., Kanamaru, R., and Watanabe, M., Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to lung cancer, Jpn. J. Cancer Res., 82, 254, 1991.
    • (1991) Jpn. J. Cancer Res. , vol.82 , pp. 254
    • Uematsu, F.1    Kikuchi, H.2    Motomiya, M.3    Abe, T.4    Sagami, I.5    Ohmachi, T.6    Wakui, A.7    Kanamaru, R.8    Watanabe, M.9
  • 115
    • 0028228772 scopus 로고
    • Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: Possible relevance to low smoking exposure
    • Uematsu, F., Ikawa, S., Kikuchi, H., Sagami, I., Kanamaru, R., Abe, T., Satoh, K., Motomiya, M., and Watanabe, M., Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: possible relevance to low smoking exposure, Pharmacogenetics, 4, 58, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 58
    • Uematsu, F.1    Ikawa, S.2    Kikuchi, H.3    Sagami, I.4    Kanamaru, R.5    Abe, T.6    Satoh, K.7    Motomiya, M.8    Watanabe, M.9
  • 116
    • 0024378451 scopus 로고
    • The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver
    • Tsutsumi, M., Lasker, J. M., Shimizu, M., Rosman, A. S., and Lieber, C. S., The intralobular distribution of ethanol-inducible P450IIE1 in rat and human liver, Hepatology, 10, 437, 1989.
    • (1989) Hepatology , vol.10 , pp. 437
    • Tsutsumi, M.1    Lasker, J.M.2    Shimizu, M.3    Rosman, A.S.4    Lieber, C.S.5
  • 118
    • 0027499273 scopus 로고
    • Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase of encoding mRNA
    • Takahashi, T., Lasker, J. M., Rosman, A. S., and Lieber, C. S., Induction of cytochrome P-4502E1 in the human liver by ethanol is caused by a corresponding increase of encoding mRNA, Hepatology, 17, 236, 1992.
    • (1992) Hepatology , vol.17 , pp. 236
    • Takahashi, T.1    Lasker, J.M.2    Rosman, A.S.3    Lieber, C.S.4
  • 121
  • 122
    • 0027272625 scopus 로고
    • The fish odour syndrome: Biochemical, familial, and clinical aspects (see comments)
    • Ayesh, R., Mitchell, S. C., Zhang, A., and Smith, R. L., The fish odour syndrome: biochemical, familial, and clinical aspects (see comments), BMJ, 307, 655, 1993.
    • (1993) BMJ , vol.307 , pp. 655
    • Ayesh, R.1    Mitchell, S.C.2    Zhang, A.3    Smith, R.L.4
  • 124
    • 0027476961 scopus 로고
    • Molecular genetics of the N-acetyltransferases
    • Grant, D. M., Molecular genetics of the N-acetyltransferases, Pharmacogenetics, 3, 45, 1993.
    • (1993) Pharmacogenetics , vol.3 , pp. 45
    • Grant, D.M.1
  • 125
    • 0027478038 scopus 로고
    • Molecular genetics of the flavin-dependent monooxygenases
    • Lawton, M. P. and Philpot, R. M., Molecular genetics of the flavin-dependent monooxygenases, Pharmacogenetics, 3, 40, 1993.
    • (1993) Pharmacogenetics , vol.3 , pp. 40
    • Lawton, M.P.1    Philpot, R.M.2
  • 126
    • 0028265810 scopus 로고
    • The mammalian flavin-containing monooxygenases: Molecular characterization and regulation of expression
    • Hines, R. N., Cashman, J. R., Philpot, R. M., Williams, D. E., and Ziegler, D. M., The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression, Toxicol. Appl. Pharmacol., 125, 1, 1994.
    • (1994) Toxicol. Appl. Pharmacol. , vol.125 , pp. 1
    • Hines, R.N.1    Cashman, J.R.2    Philpot, R.M.3    Williams, D.E.4    Ziegler, D.M.5
  • 127
    • 0021115233 scopus 로고
    • Microsomal epoxide hydrolase properties, regulation and function
    • Seidegard, J. and DePierre, J., Microsomal epoxide hydrolase properties, regulation and function, Biochim. Biophys. Acta, 695, 251, 1983.
    • (1983) Biochim. Biophys. Acta , vol.695 , pp. 251
    • Seidegard, J.1    DePierre, J.2
  • 128
    • 0027443245 scopus 로고
    • Regiospecific expression of cytochrome P-450s and microsomal epoxide hydrolase in human brain tissue
    • Farin, F. M. and Omiecinski, C. J., Regiospecific expression of cytochrome P-450s and microsomal epoxide hydrolase in human brain tissue, J. Toxicol. Environ. Health, 40, 317, 1993.
    • (1993) J. Toxicol. Environ. Health , vol.40 , pp. 317
    • Farin, F.M.1    Omiecinski, C.J.2
  • 129
    • 0028230708 scopus 로고
    • Expression of cytochrome P450s and microsomal epoxide hydrolase in primary cultures of human umbilical vein endothelial cells
    • Farin, F. M., Pohlman, T. H., and Omiecinski, C. J., Expression of cytochrome P450s and microsomal epoxide hydrolase in primary cultures of human umbilical vein endothelial cells, Toxicol. Appl. Pharmacol., 124, 1, 1994.
    • (1994) Toxicol. Appl. Pharmacol. , vol.124 , pp. 1
    • Farin, F.M.1    Pohlman, T.H.2    Omiecinski, C.J.3
  • 130
    • 0026562852 scopus 로고
    • Glutathione-S-transferase and epoxide hydrolase activity in human leukocytes in relation to risk of lung cancer and other smoking-related cancers
    • Heckbert, S. R., Weiss, N. S., Hornung, S. K., Eaton, D. L., and Motulsky, A. G., Glutathione-S-transferase and epoxide hydrolase activity in human leukocytes in relation to risk of lung cancer and other smoking-related cancers, J. Natl. Cancer Inst., 84, 414, 1992.
    • (1992) J. Natl. Cancer Inst. , vol.84 , pp. 414
    • Heckbert, S.R.1    Weiss, N.S.2    Hornung, S.K.3    Eaton, D.L.4    Motulsky, A.G.5
  • 131
    • 0028352066 scopus 로고
    • Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions
    • Gaedigk, A., Spielberg, S. P., and Grant, D. M., Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions, Pharmacogenetics, 4, 142, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 142
    • Gaedigk, A.1    Spielberg, S.P.2    Grant, D.M.3
  • 132
    • 0028295652 scopus 로고
    • Human microsomal epoxide hydrolase: Genetic polymorphism and functional expression in vitro of amino acid variants
    • Hassett, C., Aicher, L., Sidhu, J. S., and Omiecinski, C. J., Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants, Hum. Mol. Genet., 3, 421, 1994.
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 421
    • Hassett, C.1    Aicher, L.2    Sidhu, J.S.3    Omiecinski, C.J.4
  • 134
  • 135
    • 0026319263 scopus 로고
    • Human NAD(P)H: Quinone oxydoreductase (NQO1) gene structure and induction by dioxin
    • Jaiswal, A. K., Human NAD(P)H: quinone oxydoreductase (NQO1) gene structure and induction by dioxin, Biochemistry, 30, 10647, 1991.
    • (1991) Biochemistry , vol.30 , pp. 10647
    • Jaiswal, A.K.1
  • 136
    • 0023724493 scopus 로고
    • Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase
    • Jaiswal, A. K., McBride, O. W., Adesnik, M., and Nebert, D. W., Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase, J. Biol. Chem., 263, 13572, 1988.
    • (1988) J. Biol. Chem. , vol.263 , pp. 13572
    • Jaiswal, A.K.1    McBride, O.W.2    Adesnik, M.3    Nebert, D.W.4
  • 137
    • 8244224471 scopus 로고
    • NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: Characterization of a mutation which modulates DT-diaphorase activity and mytomycin sensitivity
    • Traver, R. D., Tetsuro, H., Danenberg, K. D., Stadlbauer, T. H. W., Danenberg, P. V., Ross, D., and Gibson, N. W., NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mytomycin sensitivity, Cancer Res., 1995.
    • (1995) Cancer Res.
    • Traver, R.D.1    Tetsuro, H.2    Danenberg, K.D.3    Stadlbauer, T.H.W.4    Danenberg, P.V.5    Ross, D.6    Gibson, N.W.7
  • 138
    • 0029073531 scopus 로고
    • Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking
    • Rosvold, E. A., McGlynn, K. A., Lustbader, E. D., and Buetow, K. H., Identification of an NAD(P)H:quinone oxidoreductase polymorphism and its association with lung cancer and smoking, Pharmacogenetics, 5, 199, 1995.
    • (1995) Pharmacogenetics , vol.5 , pp. 199
    • Rosvold, E.A.1    McGlynn, K.A.2    Lustbader, E.D.3    Buetow, K.H.4
  • 139
    • 0027134662 scopus 로고
    • The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP glucuronosyltransferases
    • Jim, C.-J., Miners, J. O., Burchell, B., and Mackenzie, P. I., The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP glucuronosyltransferases, Carcinogenesis, 14, 2637, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 2637
    • Jim, C.-J.1    Miners, J.O.2    Burchell, B.3    Mackenzie, P.I.4
  • 140
    • 0027422955 scopus 로고
    • Cosegregation of intragenic markers with a novel mutation that causes Crigler-Najjar type I: Implication in carrier detection and prenatal diagnosis
    • Moghrabi, N., Clarke, D. J., Burchell, B., and Boxer, M., Cosegregation of intragenic markers with a novel mutation that causes Crigler-Najjar type I: implication in carrier detection and prenatal diagnosis, Am. J. Hum. Genet., 53, 722, 1993.
    • (1993) Am. J. Hum. Genet. , vol.53 , pp. 722
    • Moghrabi, N.1    Clarke, D.J.2    Burchell, B.3    Boxer, M.4
  • 141
    • 0028837971 scopus 로고
    • (S)Oxazepam glucuronidation is inhibited by ketoprofen and other substrates of UGT2B7
    • Patel, M., Tang, B. K., and Kalow, W., (S)Oxazepam glucuronidation is inhibited by ketoprofen and other substrates of UGT2B7, Pharmacogenetics, 5, 43, 1995.
    • (1995) Pharmacogenetics , vol.5 , pp. 43
    • Patel, M.1    Tang, B.K.2    Kalow, W.3
  • 142
    • 34250943612 scopus 로고
    • Enzymatic inactivation of isonicotinic acid hydrazide in humans and animals
    • Bonicke, R. and Reif, W., Enzymatic inactivation of isonicotinic acid hydrazide in humans and animals, Arch. Exp. Pathol. Pharmakol. 220, 321, 1953.
    • (1953) Arch. Exp. Pathol. Pharmakol. , vol.220 , pp. 321
    • Bonicke, R.1    Reif, W.2
  • 143
    • 0001103663 scopus 로고
    • On the inherited basis of intraindividual constancy of isoniazid elimination in man (studies of monozygotic and dizygotic twins)
    • Bonicke, R. and Lisboa, B. P., On the inherited basis of intraindividual constancy of isoniazid elimination in man (studies of monozygotic and dizygotic twins), Naturwissenschaften, 44, 314, 1957.
    • (1957) Naturwissenschaften , vol.44 , pp. 314
    • Bonicke, R.1    Lisboa, B.P.2
  • 144
    • 0021813284 scopus 로고
    • N-acetylation pharmacogeneties
    • Weber, W. W. and Hein, D. W., N-acetylation pharmacogeneties, Pharmacol. Rev., 37, 25, 1985.
    • (1985) Pharmacol. Rev. , vol.37 , pp. 25
    • Weber, W.W.1    Hein, D.W.2
  • 145
    • 0025887858 scopus 로고
    • N-acetyltransferase polymorphism. Comparison of phenotype and genotype in humans
    • Hickman, D. and Sim, E., N-acetyltransferase polymorphism. Comparison of phenotype and genotype in humans, Biochem. Pharmacol., 42, 1007, 1991.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 1007
    • Hickman, D.1    Sim, E.2
  • 146
    • 0025344002 scopus 로고
    • Human arylamine N-acetyltransferase genes: Isolation, chromosomal localization, and functional expression
    • Blum, M., Grant, D. M., McBride, O. W., Heim, M., and Meyer, U. A., Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression, DNA Cell Biol., 9, 193, 1990.
    • (1990) DNA Cell Biol. , vol.9 , pp. 193
    • Blum, M.1    Grant, D.M.2    McBride, O.W.3    Heim, M.4    Meyer, U.A.5
  • 147
    • 0025237412 scopus 로고
    • Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver
    • Ohsako, S. and Deguchi, T., Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver, J. Biol. Chem., 265, 4630, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 4630
    • Ohsako, S.1    Deguchi, T.2
  • 148
    • 0025880699 scopus 로고
    • Structure and restriction fragment length polymorphism of genes for human liver arylamine N-acetyltransferase
    • Ebisawa, T. and Deguchi, T., Structure and restriction fragment length polymorphism of genes for human liver arylamine N-acetyltransferase, Biochem. Biophys. Res. Commun., 177, 1252, 1991.
    • (1991) Biochem. Biophys. Res. Commun. , vol.177 , pp. 1252
    • Ebisawa, T.1    Deguchi, T.2
  • 149
    • 0027183777 scopus 로고
    • Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new acetylator allele common in African-Americans
    • Bell, D. A., Taylor, J. A., Butler, M. A., Stephens, E. A., Wiest, J., Brubacker, L. H., Kadlubar, F. F., and Lucier, G. W., Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new acetylator allele common in African-Americans, Carcinogenesis, 14, 1689, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1689
    • Bell, D.A.1    Taylor, J.A.2    Butler, M.A.3    Stephens, E.A.4    Wiest, J.5    Brubacker, L.H.6    Kadlubar, F.F.7    Lucier, G.W.8
  • 150
    • 0027306025 scopus 로고
    • The structure and characteristics of a fourth allele of polymorphic n-acetyltransferase gene found in the Japanese population
    • Abe, M., Deguchi, T., and Suzuki, T., The structure and characteristics of a fourth allele of polymorphic n-acetyltransferase gene found in the Japanese population, Biochem. Biophys. Res. Commun., 191, 811, 1993.
    • (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 811
    • Abe, M.1    Deguchi, T.2    Suzuki, T.3
  • 153
    • 0029163589 scopus 로고
    • Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: Correlation with phenotypic activity
    • Cascorbi, I., Drakoulis, N., Brockmöller, J., Maurer, A., Sperling, K., and Roots, I., Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity, Am. J. Hum. Genet., 57, 581, 1995.
    • (1995) Am. J. Hum. Genet. , vol.57 , pp. 581
    • Cascorbi, I.1    Drakoulis, N.2    Brockmöller, J.3    Maurer, A.4    Sperling, K.5    Roots, I.6
  • 154
    • 0001340088 scopus 로고
    • Epidemiological studies on N-acetylation and C-center ring oxidation in neoplasia
    • Omenn, G. S. and Gelboin, H. V., Eds., Cold Spring Harbor Laboratory, New York
    • Cartwright, R. A., Epidemiological studies on N-acetylation and C-center ring oxidation in neoplasia, in Genetic Variability in Responses to Chemical Exposure, Omenn, G. S. and Gelboin, H. V., Eds., Cold Spring Harbor Laboratory, New York, 1984, 359.
    • (1984) Genetic Variability in Responses to Chemical Exposure , pp. 359
    • Cartwright, R.A.1
  • 155
    • 0022468570 scopus 로고
    • N-Acetyltransferase phenotype of patients with bladder cancer
    • Karakaya, A. E., Cok, I., Sardas, S., and Gogus, O. S., N-Acetyltransferase phenotype of patients with bladder cancer, Hum. Toxicol., 5, 333, 1989.
    • (1989) Hum. Toxicol. , vol.5 , pp. 333
    • Karakaya, A.E.1    Cok, I.2    Sardas, S.3    Gogus, O.S.4
  • 157
    • 0027999623 scopus 로고
    • Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps
    • Lang, N. P., Butler, M. A., Massengill, J. P., Lawson, M., Stotts, R. C., Hauer-Jensen, M., and Kadlubar, F. F., Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps, Cancer Epidemiol. Biomark. Prev., 3, 675, 1994.
    • (1994) Cancer Epidemiol. Biomark. Prev. , vol.3 , pp. 675
    • Lang, N.P.1    Butler, M.A.2    Massengill, J.P.3    Lawson, M.4    Stotts, R.C.5    Hauer-Jensen, M.6    Kadlubar, F.F.7
  • 158
    • 0025917067 scopus 로고
    • Diverse point mutations in the human gene for polymorphic N-acetyltransferase
    • Vatsis, K. P., Martell, K. J., and Weber, W. W., Diverse point mutations in the human gene for polymorphic N-acetyltransferase, Proc. Natl. Acad. Sci. U.S.A., 88, 6333, 1991.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 6333
    • Vatsis, K.P.1    Martell, K.J.2    Weber, W.W.3
  • 159
    • 0027218299 scopus 로고
    • Individual variability in p-aminobenzoic acid N-acetylation by human N-acetyltransferase (NAT1) or peripheral blood
    • Weber, W. W. and Vatsis, K. P., Individual variability in p-aminobenzoic acid N-acetylation by human N-acetyltransferase (NAT1) or peripheral blood, Pharmacogenetics, 3, 209, 1993.
    • (1993) Pharmacogenetics , vol.3 , pp. 209
    • Weber, W.W.1    Vatsis, K.P.2
  • 160
    • 0028844578 scopus 로고
    • Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: Association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue
    • Bell, D. A., Badawi, A. F., Lang, N. P., Ilett, K. F., Kadlubar, F. F., and Hirvonen, A., Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue, Cancer Res., 55, 5226, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5226
    • Bell, D.A.1    Badawi, A.F.2    Lang, N.P.3    Ilett, K.F.4    Kadlubar, F.F.5    Hirvonen, A.6
  • 161
    • 0028879678 scopus 로고
    • Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogenDNA adduct formation in the human urinary bladder
    • Badawi, A. F., Hirvonen, A., Bell, D. A., Lang, N. P., and Kadlubar, F. F., Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogenDNA adduct formation in the human urinary bladder, Cancer Res., 55, 5230, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5230
    • Badawi, A.F.1    Hirvonen, A.2    Bell, D.A.3    Lang, N.P.4    Kadlubar, F.F.5
  • 163
    • 0027281895 scopus 로고
    • Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases
    • Hein, D. W., Doll, M. A., Rustan, T. D., Gray, K., Feng, Y., Ferguson, R. J., and Grant, D. M., Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases, Carcinogenesis, 14, 1633, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1633
    • Hein, D.W.1    Doll, M.A.2    Rustan, T.D.3    Gray, K.4    Feng, Y.5    Ferguson, R.J.6    Grant, D.M.7
  • 165
    • 0027318721 scopus 로고
    • Glutathione S-transferases: Gene structure and regulation of expression
    • Daniel, V., Glutathione S-transferases: gene structure and regulation of expression, Crit. Rev. Biochem. Mol. Biol., 28, 173, 1993.
    • (1993) Crit. Rev. Biochem. Mol. Biol. , vol.28 , pp. 173
    • Daniel, V.1
  • 166
    • 0024269217 scopus 로고
    • Glutathione transferases - Structure and catalytic activity
    • Mannervik, B. and Danielson, U. H., Glutathione transferases - structure and catalytic activity, CRC Crit. Rev. Biochem., 23, 281, 1988.
    • (1988) CRC Crit. Rev. Biochem. , vol.23 , pp. 281
    • Mannervik, B.1    Danielson, U.H.2
  • 168
    • 0027370757 scopus 로고
    • Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer
    • Zhong, S., Wyllie, A. H., Barnes, D., Wolf, C. R., and Spurr, N. K., Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer, Carcinogenesis, 14, 1821, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1821
    • Zhong, S.1    Wyllie, A.H.2    Barnes, D.3    Wolf, C.R.4    Spurr, N.K.5
  • 169
    • 0027431942 scopus 로고
    • Use of site-directed mutagenesis of allele-specific PCR primers to
    • Fryer, A. A., Zhao, L., Alldersea, J., Pearson, W. R., and Strange, R. C., Use of site-directed mutagenesis of allele-specific PCR primers to identify the GSTM1 A, GSTM1 B, GSTM1 A,B and GSTM1 null polymorphisms at the glutathione S-transferase, GSTM1 locus, Biochem. J., 295, 313, 1993.
    • (1993) Biochem. J. , vol.295 , pp. 313
    • Fryer, A.A.1    Zhao, L.2    Alldersea, J.3    Pearson, W.R.4    Strange, R.C.5
  • 170
    • 0027306050 scopus 로고
    • Genetic risk and carcinogen exposure: A common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer
    • Bell, D. A., Taylor, J. A., Paulson, D. F., Robertson, C. N., Mohler, J. L., and Lucier, G. W., Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer, J. Natl. Cancer Inst., 85, 1159, 1993.
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 1159
    • Bell, D.A.1    Taylor, J.A.2    Paulson, D.F.3    Robertson, C.N.4    Mohler, J.L.5    Lucier, G.W.6
  • 171
    • 0028968817 scopus 로고
    • Expression and polymorphism of glutathione S-transferase in human lungs: Risk factors in smoking-related lung cancer
    • Nakajima, T., Elovaara, E., Anttila, S., Hirvonen, A., Camus, A. M., Hayes, J. D., Ketterer, B., and Vainio, H., Expression and polymorphism of glutathione S-transferase in human lungs: risk factors in smoking-related lung cancer, Carcinogenesis, 16, 707, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 707
    • Nakajima, T.1    Elovaara, E.2    Anttila, S.3    Hirvonen, A.4    Camus, A.M.5    Hayes, J.D.6    Ketterer, B.7    Vainio, H.8
  • 172
    • 0027310723 scopus 로고
    • The glutathione S-transferases: Polymerase chain reaction studies on the frequency of the GSTM1 0 genotype in patients with pituitary adenomas
    • Fryer, A. A., Zhao, L., Alldersea, J., Boggild, M. D., Perrett, C. W., Clayton, R. N., Jones, P. W., and Strange, R. C., The glutathione S-transferases: polymerase chain reaction studies on the frequency of the GSTM1 0 genotype in patients with pituitary adenomas, Carcinogenesis, 14, 563, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 563
    • Fryer, A.A.1    Zhao, L.2    Alldersea, J.3    Boggild, M.D.4    Perrett, C.W.5    Clayton, R.N.6    Jones, P.W.7    Strange, R.C.8
  • 174
    • 0027282007 scopus 로고
    • The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung
    • Hirvonen, A., Husgafvel-Pursiainen, K., Anttila, S., and Vainio, H., The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung, Carcinogenesis, 14, 1479, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1479
    • Hirvonen, A.1    Husgafvel-Pursiainen, K.2    Anttila, S.3    Vainio, H.4
  • 176
    • 0029086208 scopus 로고
    • Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and Caucasians in Los Angeles county, California
    • London, S. J., Daly, A. K., Cooper, J., Navidi, W. C., Carpenter, C. L., and Idle, J. R., Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and Caucasians in Los Angeles county, California, J. Natl. Cancer Inst., 87, 1246, 1995.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 1246
    • London, S.J.1    Daly, A.K.2    Cooper, J.3    Navidi, W.C.4    Carpenter, C.L.5    Idle, J.R.6
  • 177
    • 0028801305 scopus 로고
    • Glutathione S-transferase genotypes as risk factors for head and neck cancer
    • Trizna, Z., Clayman, G., Spitz, M. R., Briggs, K. L., and Goepfert, H., Glutathione S-transferase genotypes as risk factors for head and neck cancer, Am. J. Surgery, 170, 499, 1995.
    • (1995) Am. J. Surgery , vol.170 , pp. 499
    • Trizna, Z.1    Clayman, G.2    Spitz, M.R.3    Briggs, K.L.4    Goepfert, H.5
  • 179
    • 0029156961 scopus 로고
    • Phenotype of glutathione S-transferase Mu (GSTM1) and susceptibility to malignant melanoma
    • Lafuente, A., Molina, R., Palou, J., Castel, T., Moral, A., Trias, M., and the MMM Group, Phenotype of glutathione S-transferase Mu (GSTM1) and susceptibility to malignant melanoma, Br. J. Cancer, 72, 324, 1995.
    • (1995) Br. J. Cancer , vol.72 , pp. 324
    • Lafuente, A.1    Molina, R.2    Palou, J.3    Castel, T.4    Moral, A.5    Trias, M.6
  • 180
    • 0028179828 scopus 로고
    • Ethnic distribution of the glutathione transferase Mu 1-1 (GSTM1) null genotype in 1473 individuals and application to bladder cancer susceptibility
    • Lin, H. J., Han, C.-Y., Bernstein, D. A., Hsiao, W., Lin, B. K., and Hardy, S., Ethnic distribution of the glutathione transferase Mu 1-1 (GSTM1) null genotype in 1473 individuals and application to bladder cancer susceptibility, Carcinogenesis, 15, 1077, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1077
    • Lin, H.J.1    Han, C.-Y.2    Bernstein, D.A.3    Hsiao, W.4    Lin, B.K.5    Hardy, S.6
  • 181
    • 0027304210 scopus 로고
    • Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population
    • Nakachi, K., Imai, K., Hayashi, S.-I., and Kawajiri, K., Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population, Cancer Res., 53, 2994, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 2994
    • Nakachi, K.1    Imai, K.2    Hayashi, S.-I.3    Kawajiri, K.4
  • 182
    • 0029078019 scopus 로고
    • Genetic polymorphisms of drug-metabolizing enzymes and lung cancer susceptibility
    • Kawajiri, K., Watanabe, J., Eguchi, H., and Hayashi, S.-I., Genetic polymorphisms of drug-metabolizing enzymes and lung cancer susceptibility, Pharmacogenetics, 5, S70, 1995.
    • (1995) Pharmacogenetics , vol.5
    • Kawajiri, K.1    Watanabe, J.2    Eguchi, H.3    Hayashi, S.-I.4
  • 183
    • 0028295177 scopus 로고
    • Lung cancer risk of GSTM1 null genotype is dependent on the extent of tobacco smoke exposure
    • Kihara, M., Kihara, M., and Noda, K., Lung cancer risk of GSTM1 null genotype is dependent on the extent of tobacco smoke exposure, Carcinogenesis, 15, 415, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 415
    • Kihara, M.1    Kihara, M.2    Noda, K.3
  • 184
    • 0029010611 scopus 로고
    • Distribution of GSTM1 null genotype in relation to gender, age and smoking status in Japanese lung cancer patients
    • Kihara, M., Noda, K., and Kihara, M., Distribution of GSTM1 null genotype in relation to gender, age and smoking status in Japanese lung cancer patients, Pharmacogenetics, 5, S74, 1995.
    • (1995) Pharmacogenetics , vol.5
    • Kihara, M.1    Noda, K.2    Kihara, M.3
  • 185
    • 0028179726 scopus 로고
    • Modulation of urinary mutagenicity by genetically determined carcinogen metabolism in smokers
    • Hirvonen, A., Nylund, L., Kociba, P., Husgafvel-Pursiainen, K., and Vainio, H., Modulation of urinary mutagenicity by genetically determined carcinogen metabolism in smokers, Carcinogenesis, 15, 813, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 813
    • Hirvonen, A.1    Nylund, L.2    Kociba, P.3    Husgafvel-Pursiainen, K.4    Vainio, H.5
  • 186
    • 0029156516 scopus 로고
    • Pulmonary expression of glutathione S-transferase M3 in lung cancer patients: Association with GSTM1 polymorphism, smoking, and asbestos exposure
    • Anttila, S., Luostarinen, L., Hirvonen, A., Elovaara, E., Karjalainen, A., Nurminen, T., Hayes, J. D., Vainio, H., and Ketterer, B., Pulmonary expression of glutathione S-transferase M3 in lung cancer patients: association with GSTM1 polymorphism, smoking, and asbestos exposure, Cancer Res., 55, 3305, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3305
    • Anttila, S.1    Luostarinen, L.2    Hirvonen, A.3    Elovaara, E.4    Karjalainen, A.5    Nurminen, T.6    Hayes, J.D.7    Vainio, H.8    Ketterer, B.9
  • 187
  • 188
    • 0029077270 scopus 로고
    • Susceptibility to astrocytoma and meningioma: Influence of allelism at glutathione S-transferase (GSTT1 and GSTM1) and cytochrome P-450 (CYP2D6) loci
    • Elexpuru-Camiruaga, J., Buxton, N., Kandula, V., Dias, P., Campbell, D., McIntosh, J., Broome, J., Jones, P., Inskip, A., Alldersea, J., et al., Susceptibility to astrocytoma and meningioma: influence of allelism at glutathione S-transferase (GSTT1 and GSTM1) and cytochrome P-450 (CYP2D6) loci, Cancer Res., 55, 4237, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4237
    • Elexpuru-Camiruaga, J.1    Buxton, N.2    Kandula, V.3    Dias, P.4    Campbell, D.5    McIntosh, J.6    Broome, J.7    Jones, P.8    Inskip, A.9    Alldersea, J.10
  • 189
    • 0028587816 scopus 로고
    • Theta class glutathione S-transferase GSTT1 genotypes and susceptibility to cervical neoplasia: Interactions with GSTM1, CYP2D6 and smoking
    • Warwick, A., Sarhanis, P., Redman, C., Pemble, S., Taylor, J. B., Ketterer, B., Jones, P., Alldersea, J., Gilford, J., Yengi, L., et al., Theta class glutathione S-transferase GSTT1 genotypes and susceptibility to cervical neoplasia: interactions with GSTM1, CYP2D6 and smoking, Carcinogenesis, 15, 2841, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 2841
    • Warwick, A.1    Sarhanis, P.2    Redman, C.3    Pemble, S.4    Taylor, J.B.5    Ketterer, B.6    Jones, P.7    Alldersea, J.8    Gilford, J.9    Yengi, L.10
  • 190
    • 0024343858 scopus 로고
    • Human P450PA (P-450-1A2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic amines
    • Butler, M. A., Iwasaki, M., Guengerich, F. P., and Kadlubar, F. F., Human P450PA (P-450-1A2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic amines, Proc. Natl. Acad. Sci. U.S.A., 86, 7696, 1989.
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 7696
    • Butler, M.A.1    Iwasaki, M.2    Guengerich, F.P.3    Kadlubar, F.F.4
  • 191
    • 0025848338 scopus 로고
    • A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple cytochrome P450s including the polymorphic cytochrome P4502D6
    • Crespi, C. L., Penman, B. W., Gelboin, H. V., and Gonzalez, F. J., A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple cytochrome P450s including the polymorphic cytochrome P4502D6, Carcinogenesis, 12, 1197, 1991.
    • (1991) Carcinogenesis , vol.12 , pp. 1197
    • Crespi, C.L.1    Penman, B.W.2    Gelboin, H.V.3    Gonzalez, F.J.4
  • 192
    • 0024445437 scopus 로고
    • Human CYP1A2. Sequence, gene structure, comparison with the mouse and rat orthologous gene, and genetic differences in liver 1A2 mRNA concentrations
    • Ikeya, K., Jaiswal, A. K., Owens, R. A., Jones, J. E., Nebert, D. W., and Kimura, S., Human CYP1A2. Sequence, gene structure, comparison with the mouse and rat orthologous gene, and genetic differences in liver 1A2 mRNA concentrations, Mol. Endocrinol., 3, 1399, 1989.
    • (1989) Mol. Endocrinol. , vol.3 , pp. 1399
    • Ikeya, K.1    Jaiswal, A.K.2    Owens, R.A.3    Jones, J.E.4    Nebert, D.W.5    Kimura, S.6
  • 193
    • 0027203704 scopus 로고
    • Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes
    • Yamazaki, H., Mimura, M., Oda, Y., Inui, Y., Shiraga, T., Iwasaki, K., Guengerich, F. P., and Shimada, T., Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes, Carcinogenesis, 14, 1271, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1271
    • Yamazaki, H.1    Mimura, M.2    Oda, Y.3    Inui, Y.4    Shiraga, T.5    Iwasaki, K.6    Guengerich, F.P.7    Shimada, T.8
  • 195
    • 0027077438 scopus 로고
    • Characterization of human lung microsomal cytochrome P4501A1 and its role in the oxidation of chemical carcinogens
    • Shimada, T., Yun, C.-H., Hiroshi, Y., Gautier, J.-C., Beaune, P. H., and Guengerich, F. P., Characterization of human lung microsomal cytochrome P4501A1 and its role in the oxidation of chemical carcinogens, Mol. Pharmacol., 41, 856, 1992.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 856
    • Shimada, T.1    Yun, C.-H.2    Hiroshi, Y.3    Gautier, J.-C.4    Beaune, P.H.5    Guengerich, F.P.6
  • 197
    • 0017324174 scopus 로고
    • Comparative metabolism of benzo(a)pyrene and drugs in human liver
    • Kapitulnik, J., Poppers, P. J., and Conney, A. H., Comparative metabolism of benzo(a)pyrene and drugs in human liver, Clin. Pharmacol. Ther., 21, 166, 1977.
    • (1977) Clin. Pharmacol. Ther. , vol.21 , pp. 166
    • Kapitulnik, J.1    Poppers, P.J.2    Conney, A.H.3
  • 198
    • 0025214234 scopus 로고
    • Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity
    • Miles, J. S., McLaren, A. W., Forrester, L. M., Glancey, M. J., Lang, M. A., and Wolf, C. R., Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity, Biochem. J., 267, 365, 1990.
    • (1990) Biochem. J. , vol.267 , pp. 365
    • Miles, J.S.1    McLaren, A.W.2    Forrester, L.M.3    Glancey, M.J.4    Lang, M.A.5    Wolf, C.R.6
  • 199
    • 0025022689 scopus 로고
    • The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
    • Yamano, S., Tatsuno, J., and Gonzalez, F. J., The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes, Biochemistry, 29, 1322, 1990.
    • (1990) Biochemistry , vol.29 , pp. 1322
    • Yamano, S.1    Tatsuno, J.2    Gonzalez, F.J.3
  • 200
    • 0025777078 scopus 로고
    • Isolation and characterization of a cytochrome P-450 of the IIA subfamily from human liver microsomes
    • Maurice, M., Emiliani, S., Dalet-Beluche, I., Derancourt, J., and Lange, R., Isolation and characterization of a cytochrome P-450 of the IIA subfamily from human liver microsomes, Eur. J. Biochem., 200, 365, 1991.
    • (1991) Eur. J. Biochem. , vol.200 , pp. 365
    • Maurice, M.1    Emiliani, S.2    Dalet-Beluche, I.3    Derancourt, J.4    Lange, R.5
  • 202
    • 0023812216 scopus 로고
    • Purification and characterization of two unique forms of cytochrome P450 from rabbit nasal microsomes
    • Ding, X. and Coon, M. J., Purification and characterization of two unique forms of cytochrome P450 from rabbit nasal microsomes, Biochemistry, 27, 8330, 1988.
    • (1988) Biochemistry , vol.27 , pp. 8330
    • Ding, X.1    Coon, M.J.2
  • 203
    • 0029048772 scopus 로고
    • The CYP2A gene subfamily: Species differences, regulation, catalytic activities and role in chemical carcinogenesis
    • Fernandez-Salguero, P. and Gonzalez, F. J., The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis, Pharmacogenetics, 5, S123, 1995.
    • (1995) Pharmacogenetics , vol.5
    • Fernandez-Salguero, P.1    Gonzalez, F.J.2
  • 204
    • 0025736365 scopus 로고
    • Localization of CYP2F1 by multipoint linkage analysis and pulse-field gel electrophoresis
    • Bale, A. E., Mitchell, A. L., Gonzalez, F. J., and McBride, O. W., Localization of CYP2F1 by multipoint linkage analysis and pulse-field gel electrophoresis, Genomics, 10, 284, 1991.
    • (1991) Genomics , vol.10 , pp. 284
    • Bale, A.E.1    Mitchell, A.L.2    Gonzalez, F.J.3    McBride, O.W.4
  • 205
    • 0023718998 scopus 로고
    • Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4′-hydroxylase
    • Ged, C., Umbenhauer, D. R., Bellew, T. M., Bork, R. W., Srivastava, P. K., Shinriki, N., Lloyd, R. S., and Guengerich, F. P., Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4′-hydroxylase, Biochemistry, 27, 6929, 1988.
    • (1988) Biochemistry , vol.27 , pp. 6929
    • Ged, C.1    Umbenhauer, D.R.2    Bellew, T.M.3    Bork, R.W.4    Srivastava, P.K.5    Shinriki, N.6    Lloyd, R.S.7    Guengerich, F.P.8
  • 206
    • 0028068016 scopus 로고
    • Fluorescence in situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1
    • Inoue, K., Inazawa, J., Suzuki, Y., Shimada, T., Yamazaki, H., Guengerich, F. P., and Abe, T., Fluorescence in situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1, Jpn. J. Hum. Genet., 39, 337, 1994.
    • (1994) Jpn. J. Hum. Genet. , vol.39 , pp. 337
    • Inoue, K.1    Inazawa, J.2    Suzuki, Y.3    Shimada, T.4    Yamazaki, H.5    Guengerich, F.P.6    Abe, T.7
  • 207
    • 0021237993 scopus 로고
    • Pharmacogenetics of mephenytoin: New drug hydroxylation polymorphism in man
    • Kupfer, A. and Preisig, R., Pharmacogenetics of mephenytoin: new drug hydroxylation polymorphism in man, Eur. J. Clin. Pharmacol., 26, 753, 1984.
    • (1984) Eur. J. Clin. Pharmacol. , vol.26 , pp. 753
    • Kupfer, A.1    Preisig, R.2
  • 210
    • 0027445449 scopus 로고
    • Isolation and characterization of human liver cytochrome P450 2C19: Correlation between 2C19 and S-mephenytoin 4′-hydroxylation
    • Wrighton, S. A., Stevens, J. C., Becker, G. W., and VandenBranden, M., Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4′-hydroxylation, Arch. Biochem. Biophys., 306, 240, 1993.
    • (1993) Arch. Biochem. Biophys. , vol.306 , pp. 240
    • Wrighton, S.A.1    Stevens, J.C.2    Becker, G.W.3    Vandenbranden, M.4
  • 211
    • 0028590127 scopus 로고
    • Biochemistry and molecular biology of the human CYP2C subfamily
    • Goldstein, J. A. and de Morais, S.M., Biochemistry and molecular biology of the human CYP2C subfamily, Pharmacogenetics, 4, 285, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 285
    • Goldstein, J.A.1    De Morais, S.M.2
  • 212
    • 0028998678 scopus 로고
    • Phenotyping of CYP2C19 with enantio-specific HPLC-quantificationof R- and S-mephenytoin and comparison with the intron4/exon5 G→A-splice site mutation
    • Brockmoller, J., Rost, K. L., Gross, D., Schenkel, A., and Roots, I., Phenotyping of CYP2C19 with enantio-specific HPLC-quantificationof R- and S-mephenytoin and comparison with the intron4/exon5 G→A-splice site mutation, Pharmacogenetics, 5, 80, 1995.
    • (1995) Pharmacogenetics , vol.5 , pp. 80
    • Brockmoller, J.1    Rost, K.L.2    Gross, D.3    Schenkel, A.4    Roots, I.5
  • 213
    • 0028207548 scopus 로고
    • Stereoselective disposition of hexobarbital and its metabolites: Relationship to the S-mephenytoin polymorphism in Caucasian and Chinese subjects
    • Adedoyin, A., Prakash, C., O'Shea, D., Blair, I. A., and Wilkinson, G. R., Stereoselective disposition of hexobarbital and its metabolites: relationship to the S-mephenytoin polymorphism in Caucasian and Chinese subjects, Pharmacogenetics, 4, 27, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 27
    • Adedoyin, A.1    Prakash, C.2    O'Shea, D.3    Blair, I.A.4    Wilkinson, G.R.5
  • 214
    • 0028589604 scopus 로고
    • Lack of low Km diazepam N-demethylase in livers of poor metabolizers for S-mephenytoin 4′-hydroxylation
    • Yasumori, T., Li, Q. H., Yamazoe, Y., Ueda, M., Tsuzuki, T., and Kato, R., Lack of low Km diazepam N-demethylase in livers of poor metabolizers for S-mephenytoin 4′-hydroxylation, Pharmacogenetics, 4, 323, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 323
    • Yasumori, T.1    Li, Q.H.2    Yamazoe, Y.3    Ueda, M.4    Tsuzuki, T.5    Kato, R.6
  • 215
    • 0027744044 scopus 로고
    • Cytochrome P450 mediated metabolism of diazepam in human and rat: Involvement of human CYP2C in N-demethylation in the substrate concentration-dependent manner
    • Yasumori, T., Nagata, K., Yang, S. K., Chen, L. S., Murayama, N., Yamazoe, Y., and Kato, R., Cytochrome P450 mediated metabolism of diazepam in human and rat: involvement of human CYP2C in N-demethylation in the substrate concentration-dependent manner, Pharmacogenetics, 3, 291, 1993.
    • (1993) Pharmacogenetics , vol.3 , pp. 291
    • Yasumori, T.1    Nagata, K.2    Yang, S.K.3    Chen, L.S.4    Murayama, N.5    Yamazoe, Y.6    Kato, R.7
  • 216
    • 0027954464 scopus 로고
    • Taxol metabolism by human liver microsomes: Identification of cytochrome P450 isozymes involved in its biotransformation
    • Cresteil, T., Monsarrat, B., Alvinerie, P., Treluyer, J. M., Vieira, I., and Wright, M., Taxol metabolism by human liver microsomes: identification of cytochrome P450 isozymes involved in its biotransformation, Cancer Res., 54, 386, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 386
    • Cresteil, T.1    Monsarrat, B.2    Alvinerie, P.3    Treluyer, J.M.4    Vieira, I.5    Wright, M.6
  • 217
    • 0028036727 scopus 로고
    • Selective biotransformation of taxol to 6α-hydrotaxol by human cytochrome P450 2C8
    • Rahman, A., Korzekwa, K. R., Grogan, J., Gonzalez, F. J., and Harris, J. W., Selective biotransformation of taxol to 6α-hydrotaxol by human cytochrome P450 2C8, Cancer Res., 54, 5543, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 5543
    • Rahman, A.1    Korzekwa, K.R.2    Grogan, J.3    Gonzalez, F.J.4    Harris, J.W.5
  • 218
    • 0028071759 scopus 로고
    • Noninvasive tests of CYP3A enzymes
    • Watkins, P. B., Noninvasive tests of CYP3A enzymes, Pharmacogenetics, 4, 171, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 171
    • Watkins, P.B.1
  • 219
    • 0024343166 scopus 로고
    • Nifepidine: Variability in its kinetics and metabolism in man
    • Breimer, D. D., Schellens, J. M. H., and Soons, P. A., Nifepidine: variability in its kinetics and metabolism in man, Pharmacol. Ther., 44, 445, 1989.
    • (1989) Pharmacol. Ther. , vol.44 , pp. 445
    • Breimer, D.D.1    Schellens, J.M.H.2    Soons, P.A.3
  • 220
    • 0027077439 scopus 로고
    • Human liver microsomal N-hydroxylation of dapsone by cytochrome P4503A4
    • Fleming, C. M., Branch, R. A., Wilkinson, G. R., and Guengerich, F. P., Human liver microsomal N-hydroxylation of dapsone by cytochrome P4503A4, Mol. Pharmacol., 41, 975, 1992.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 975
    • Fleming, C.M.1    Branch, R.A.2    Wilkinson, G.R.3    Guengerich, F.P.4
  • 227
    • 0027486997 scopus 로고
    • Molecular basis for the polymorphic forms of human serum paraoxonase/arylesterase: Glutamine or arginine at position 191, for the respective A or B allozymes
    • Adkins, S., Gan, K. N., Mody, M., and La Du, B. N., Molecular basis for the polymorphic forms of human serum paraoxonase/arylesterase: glutamine or arginine at position 191, for the respective A or B allozymes, Am. J. Hum. Genet., 52, 598, 1993.
    • (1993) Am. J. Hum. Genet. , vol.52 , pp. 598
    • Adkins, S.1    Gan, K.N.2    Mody, M.3    La Du, B.N.4
  • 228
    • 0026240155 scopus 로고
    • Analysis of the serum paraoxonase/arylesterase polymorphism in a Turkish population
    • Karakaya, A., Suzen, S., Sardas, S., Karakaya, A. E., and Vural, N., Analysis of the serum paraoxonase/arylesterase polymorphism in a Turkish population, Pharmacogenetics, 1, 58, 1991.
    • (1991) Pharmacogenetics , vol.1 , pp. 58
    • Karakaya, A.1    Suzen, S.2    Sardas, S.3    Karakaya, A.E.4    Vural, N.5
  • 229
    • 0026052749 scopus 로고
    • Serum paraoxonase in three populations of Southeast Asia
    • Roy, A. C., Saha, N., Tay, J. S., and Ratnam, S. S., Serum paraoxonase in three populations of Southeast Asia, Hum. Hered., 41, 265, 1991.
    • (1991) Hum. Hered. , vol.41 , pp. 265
    • Roy, A.C.1    Saha, N.2    Tay, J.S.3    Ratnam, S.S.4
  • 230
    • 0027192349 scopus 로고
    • Fundamentals of case-control studies
    • Clavel, J. and Hemon, D., Fundamentals of case-control studies, Pharmacogenetics, 3, 160, 1993.
    • (1993) Pharmacogenetics , vol.3 , pp. 160
    • Clavel, J.1    Hemon, D.2
  • 231
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander, E. S. and Schork, N. J., Genetic dissection of complex traits, Science, 265, 2037, 1994.
    • (1994) Science , vol.265 , pp. 2037
    • Lander, E.S.1    Schork, N.J.2
  • 232
    • 0027243501 scopus 로고
    • Finding genes that cause human hypertension
    • Lifton, R. P. and Jeunemaitre, X., Finding genes that cause human hypertension, J. Hypertens., 11, 231, 1993.
    • (1993) J. Hypertens. , vol.11 , pp. 231
    • Lifton, R.P.1    Jeunemaitre, X.2
  • 233
    • 0026501994 scopus 로고
    • Sib pair linkage analysis of renin gene haplotypes in human essential hypertension
    • Jeunemaitre, X., Rigat, B., Charru, A., Houot, A. M., Soubrier, F., and Corvol, P., Sib pair linkage analysis of renin gene haplotypes in human essential hypertension, Hum. Genet., 88, 301, 1992.
    • (1992) Hum. Genet. , vol.88 , pp. 301
    • Jeunemaitre, X.1    Rigat, B.2    Charru, A.3    Houot, A.M.4    Soubrier, F.5    Corvol, P.6
  • 235
    • 0028923282 scopus 로고
    • Analysis of the CD3 gene region and type 1 diabetes: Application of fluorescence-based technology to linkage disequilibrium mapping
    • Pritchard, L. E., Kawaguchi, Y., Reed, P. W., Copeman, J. B., Davies, J. L., Barnett, A. H., Bain, S. C., and Todd, J. A., Analysis of the CD3 gene region and type 1 diabetes: application of fluorescence-based technology to linkage disequilibrium mapping, Hum. Mol. Genet., 4, 197, 1995.
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 197
    • Pritchard, L.E.1    Kawaguchi, Y.2    Reed, P.W.3    Copeman, J.B.4    Davies, J.L.5    Barnett, A.H.6    Bain, S.C.7    Todd, J.A.8
  • 242
    • 85036445292 scopus 로고    scopus 로고
    • personal communication
    • Meyer, U. A., personal communication.
    • Meyer, U.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.