Peptide-specific killing of antigen-presenting cells by a recombinant antibody-toxin fusion protein targeted to major histocompatibility complex/peptide class I complexes with T cell receptor-like specificity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 9, 1997, Pages 4631-4636

  Reiter, Yoram ^a   Di Carlo, Angelina ^a   Fugger, Lars ^c   Engberg, Jan ^b   Pastan, Ira ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c Rigshospitalet   (Denmark)

Author keywords

Immunotoxin; Targeted therapy

Indexed keywords

HYBRID PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOTOXIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RECOMBINANT PROTEIN; T LYMPHOCYTE RECEPTOR; TUMOR PROTEIN;

ANIMAL CELL; ANTIBODY SPECIFICITY; ANTIGEN PRESENTING CELL; ARTICLE; CANCER IMMUNOTHERAPY; CELL KILLING; IMMUNOTOXICITY; INFLUENZA VIRUS; NONHUMAN; PRIORITY JOURNAL; TARGET CELL DESTRUCTION;

ADP RIBOSE TRANSFERASES; ANIMALS; ANTIBODIES; ANTIGEN-PRESENTING CELLS; BACTERIAL TOXINS; CYTOTOXICITY, IMMUNOLOGIC; EXOTOXINS; H-2 ANTIGENS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOTHERAPY; IMMUNOTOXINS; INFLUENZA A VIRUS; MICE; PEPTIDES; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; PSEUDOMONAS AERUGINOSA; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SENSITIVITY AND SPECIFICITY; VIRULENCE FACTORS;

EID: 0030935662     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.9.4631     Document Type: Article

References (23)

1. Rosenberg, S. A. (1996) Annu. Rev. Med. 47, 481-491.
2. Goodnow, C. C. (1996) Proc. Natl. Acad. Sci. USA 93, 2264-2271.
3. Steinman, L. (1996) Proc. Natl. Acad. Sci. USA 93, 2253-2256.
4. Andersen, P. S., Stryhn, A., Hansen, B. E., Fugger, L., Engberg, J. & Buus, S. (1996) Proc. Natl. Acad. Sci. USA 93, 1820-1824.
5. Stryhn, A., Anderson, P. S., Pedersen, L. O., Svejgaard, A., Holm, A., Thorpe, C. J., Fugger, L., Buus, S. & Engberg, J. (1996) Proc. Natl. Acad. Sci. USA 93, 10338-10342.
6. Pastan, I. & FitzGerald, D. (1991) Science 254, 1173-1137.
7. Pastan, I., Chaudhary, V. & FitzGerald, D. (1992) Annu. Rev. Biochem. 61, 331-354.
8. Brinkmann, U., Pai, L. H., FitzGerald, D. J. & Pastan, I. (1991) Proc. Natl. Acad. Sci. USA 88, 8616-8620.
9. Reiter, Y., Brinkmann, U., Lee, B. K. & Pastan, I. (1996) Nat. Biotechnol. 14, 1239-1245.
10. Ljunggren, H.-G., Stam, N. J., Ohlen, C., Neefjes, J. J., Hoglund, P., Heemels, M. T., Bustin, J., Schumacher, T. N., Townsend, A., Karre, K. & Ploegh, H. L. (1990) Nature (London) 346, 476-480.
11. Stryhn, A., Pedersen, L. O., Ortiz-Navarrete, V. & Buus, S. (1994) Eur. J. Immunol. 24, 1404-1409.
12. Cox, A. L., Skipper, J., Chen, Y., Henderson, R. A., Darrow, T. L., Shabanowitz, J., Engelhard, V. H., Hunt, D. F. & Slingluff, C. L., Jr. (1994) Science 264, 716-719.
13. Van Der Bruggen, P. Traversari, C. Chomez, P., Lurquin, C., De Plaen, E., Van den Eynde, B., Knuth, A. & Boon, T. (199) Science 254, 1643-1647.
14. Gaugler, B., van den Eynde, B., van der Bruggen, P., Romero, P., Gaforio, J. J., De Plaen, E., Lethe, B., Brasseur, F. & Boon, T. (1994) J. Exp. Med. 179, 921-930.
15. Brichard, V., van Pel, A., Wolfel, T., Wolfel, C., De Plaen, E., Lethe, B., Cooli, P. & Boon, T. (1993) J. Exp. Med. 178, 489-495.
16. Kawakami, Y., Eliyahu, S., Delgano, C. H., Robhins, P. F., Rivoltini, L., Topalian, S. L., Miki, T. & Rosenberg, S. A. (1994) Proc. Natl. Acad. Sci. USA 91, 3515-3519.
17. Kawakami, Y., Eliyahu, S., Delgano, C. H., Robbins, P. F., Sakaguchi, K., Appella, E., Yannelli, J. R., Adema, G. J., Miki, T. & Rosenberg, S. A. (1994) Proc. Natl. Acad. Sci. USA 91, 6458-6462.
18. Kawakami, Y., Eliyahu, S., Sakaguchi, K., Robbins, P. F., Rivoltini, L., Yannelli, J. R., Appella, E. & Rosenberg, S. A (1994) J. Exp. Med. 180, 347-352.
19. Fremont, D. H., Matsumura, M., Stura, E. A., Peterson, P. A. & Wilson I. A. (1992) Science 257, 919-927.
20. Young, A. C., Zhang, W., Sacchettini, J. C. & Nathenson, S. F. (1994) Cell 76, 39-50.
21. Bjorkman, P. J., Saper, M. A., Samraoui, B., Bennett, W. S., Strominger, J. L. & Wiley, D. C. (1987) Nature (London) 329, 512-518.
22. Winter, G., Griffiths, A. D., Hawkins, R. E. & Hoogenboom, H. R. (1994) Annu. Rev. Immunol. 12, 433-455.
23. Barbas, C. F., III (1995) Nat. Med. 1, 837-839.