메뉴 건너뛰기




Volumn 208, Issue 4, 1997, Pages 466-481

Rescue of the limb deformity in hammertoe mutant mice by retinoic acid- induced cell death

Author keywords

cell death; limb mutant; retinoic acid; retinoic acid receptor

Indexed keywords

RETINOIC ACID; RETINOID X RECEPTOR;

EID: 0030935138     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(199704)208:4<466::AID-AJA3>3.0.CO;2-G     Document Type: Article
Times cited : (44)

References (59)
  • 1
    • 0024441643 scopus 로고
    • Retinoic acid-induced limb reduction defects: Perturbation of zones of programmed cell death as a pathogenetic mechanism
    • Alles, A.J., and Sulik, K.K. (1989) Retinoic acid-induced limb reduction defects: perturbation of zones of programmed cell death as a pathogenetic mechanism. Teratology 40:163-171.
    • (1989) Teratology , vol.40 , pp. 163-171
    • Alles, A.J.1    Sulik, K.K.2
  • 2
    • 0025058394 scopus 로고
    • Retinoic acid-induced spina bifida: Evidence for a pathogenetic mechanism
    • Alles, A.J., and Sulik, K.K. (1990) Retinoic acid-induced spina bifida: evidence for a pathogenetic mechanism. Development 108:73-81.
    • (1990) Development , vol.108 , pp. 73-81
    • Alles, A.J.1    Sulik, K.K.2
  • 3
    • 0026457187 scopus 로고
    • Retinoids and the molecular basis of limb patterning
    • Brown, J.M., and Tickle, C. (1992) Retinoids and the molecular basis of limb patterning. Comp. Biochem. Physiol. A 103:641-647.
    • (1992) Comp. Biochem. Physiol. A , vol.103 , pp. 641-647
    • Brown, J.M.1    Tickle, C.2
  • 4
    • 0028158930 scopus 로고
    • A concentration gradient of retinoids in the early Xenopus laevis embryo
    • Chen, Y., Huang, L., and Solursh, M. (1994) A concentration gradient of retinoids in the early Xenopus laevis embryo. Dev. Biol. 161: 70-76.
    • (1994) Dev. Biol. , vol.161 , pp. 70-76
    • Chen, Y.1    Huang, L.2    Solursh, M.3
  • 5
    • 0026708381 scopus 로고
    • RA: Role of the chicken homeobox-containing genes Ghox 4.6 and Ghox 8 in the specification of positional identities during the development of normal and polydactylous chick limb buds
    • Coelho, C.N.D., Upholt, W.B., and Kosher, R.A. (1992) RA: role of the chicken homeobox-containing genes Ghox 4.6 and Ghox 8 in the specification of positional identities during the development of normal and polydactylous chick limb buds. Development 115:629-637.
    • (1992) Development , vol.115 , pp. 629-637
    • Coelho, C.N.D.1    Upholt, W.B.2    Kosher, R.A.3
  • 6
    • 0027748955 scopus 로고
    • Roles of the chicken homeobox-containing genes GHox-8, GHox-7, and GHox-4.6 in pattern formation during limb development
    • Fallon, J.F., Goetinck, P.F., Kelley, R.O., and Stocum, D.L., New York: Wiley-Liss
    • Coelho, C.N.D., Sumoy, L.L., Rogina, B., Upholt, W.B., and Kosher, R.A. (1993) Roles of the chicken homeobox-containing genes GHox-8, GHox-7, and GHox-4.6 in pattern formation during limb development. In: "Limb Development and Regeneration," Fallon, J.F., Goetinck, P.F., Kelley, R.O., and Stocum, D.L., New York: Wiley-Liss, pp 61-70.
    • (1993) Limb Development and Regeneration , pp. 61-70
    • Coelho, C.N.D.1    Sumoy, L.L.2    Rogina, B.3    Upholt, W.B.4    Kosher, R.A.5
  • 7
    • 0028072053 scopus 로고
    • Ligand-dependent occupancy of the retinoic acid receptor beta 2 promoter in vivo
    • Dey, A., Minucci, S., and Ozato, K. (1994) Ligand-dependent occupancy of the retinoic acid receptor beta 2 promoter in vivo. Mol. Cell Biol. 14:8191-8201.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 8191-8201
    • Dey, A.1    Minucci, S.2    Ozato, K.3
  • 8
    • 0024367398 scopus 로고
    • Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse
    • Dollé, P., Ruberte, E., Kastner, P., Petkovich, M., Stoner, C.M., Gudas, L.J., Chambon, P. (1989) Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse. Nature 342:702-705.
    • (1989) Nature , vol.342 , pp. 702-705
    • Dollé, P.1    Ruberte, E.2    Kastner, P.3    Petkovich, M.4    Stoner, C.M.5    Gudas, L.J.6    Chambon, P.7
  • 9
    • 0025685315 scopus 로고
    • Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis
    • Dollé, P., Ruberte, E., Leroy, P., Morriss-Kay, G., and Chambon, P. (1990) Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. Development 110:1133-1151.
    • (1990) Development , vol.110 , pp. 1133-1151
    • Dollé, P.1    Ruberte, E.2    Leroy, P.3    Morriss-Kay, G.4    Chambon, P.5
  • 10
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor super-family
    • Evans, R.M. (1988) The steroid and thyroid hormone receptor super-family. Science 240:889-895.
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 11
    • 0020043199 scopus 로고
    • Cell death in the mammalian visual system during normal development: II. Superior colliculus
    • Finlay, B.L., Berg, A.T., and Sengelaub, D.R. (1982) Cell death in the mammalian visual system during normal development: II. Superior colliculus. J. Comp. Neurol. 204:318-324.
    • (1982) J. Comp. Neurol. , vol.204 , pp. 318-324
    • Finlay, B.L.1    Berg, A.T.2    Sengelaub, D.R.3
  • 12
    • 0027375474 scopus 로고
    • Internucleosomal DNA fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg bud
    • Garcia-Martinez, V., Macias, D., Ganan, Y., Garcia-Lobo, J.M., Francia, M.V., Fernandez-Teran, M.A., Hurle, J.M. (1993) Internucleosomal DNA fragmentation and programmed cell death (apoptosis) in the interdigital tissue of the embryonic chick leg bud. J. Cell. Sci. 106:201-208.
    • (1993) J. Cell. Sci. , vol.106 , pp. 201-208
    • Garcia-Martinez, V.1    Macias, D.2    Ganan, Y.3    Garcia-Lobo, J.M.4    Francia, M.V.5    Fernandez-Teran, M.A.6    Hurle, J.M.7
  • 13
    • 0023797380 scopus 로고
    • Nuclear receptors enhance our understanding of transcription regulation
    • Green, S., and Chambon, P. (1988) Nuclear receptors enhance our understanding of transcription regulation. Trends Genet. 4:309-314.
    • (1988) Trends Genet. , vol.4 , pp. 309-314
    • Green, S.1    Chambon, P.2
  • 14
    • 0346605770 scopus 로고
    • The regulation of gene expression by retinoids in normal and tumorigenic epithelial cells
    • Gudas, L., and Hu, L. (1993) The regulation of gene expression by retinoids in normal and tumorigenic epithelial cells. Proc. Annu. Meet. Am. Assoc. Cancer Res. 34:588-589.
    • (1993) Proc. Annu. Meet. Am. Assoc. Cancer Res. , vol.34 , pp. 588-589
    • Gudas, L.1    Hu, L.2
  • 15
    • 0024574583 scopus 로고
    • A new family of mouse homeobox-containing genes: Molecular structure, chromosomal location, and developmental expression of Hox-7.1
    • Hill, R.E., Jones, P.F., Rees, A.R., Sime, C.M., Justice, M.J., Copeland, N.G., Jenkins, N.A., Graham, E., and Davidson, D.R. (1989) A new family of mouse homeobox-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1. Genes Dev. 3:26-37.
    • (1989) Genes Dev. , vol.3 , pp. 26-37
    • Hill, R.E.1    Jones, P.F.2    Rees, A.R.3    Sime, C.M.4    Justice, M.J.5    Copeland, N.G.6    Jenkins, N.A.7    Graham, E.8    Davidson, D.R.9
  • 16
    • 0002134977 scopus 로고
    • Cell death in embryogenesis
    • Bowen, I.D. and Lockshin, R.A. (ed). London: Chapman and Hall
    • Hinchliffe, J.R. (1981) Cell death in embryogenesis. In: "Cell Death in Biology and Pathology," Bowen, I.D. and Lockshin, R.A. (ed). London: Chapman and Hall, pp 35-69.
    • (1981) Cell Death in Biology and Pathology , pp. 35-69
    • Hinchliffe, J.R.1
  • 18
    • 0015758648 scopus 로고
    • Cell death and the development of limb form and skeletal pattern in normal and wingless (ws) chick embryos
    • Hinchliffe, J.R., and Ede, D.A. (1973) Cell death and the development of limb form and skeletal pattern in normal and wingless (ws) chick embryos. J. Embryol. Exp. Morphol. 30:753-772.
    • (1973) J. Embryol. Exp. Morphol. , vol.30 , pp. 753-772
    • Hinchliffe, J.R.1    Ede, D.A.2
  • 19
    • 0021716522 scopus 로고
    • The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80: Macrophages associated with epithelia
    • Hume, D.A., Perry, V.H., and Gordon, S. (1984) The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80: macrophages associated with epithelia. Anat. Rec. 210:503-512.
    • (1984) Anat. Rec. , vol.210 , pp. 503-512
    • Hume, D.A.1    Perry, V.H.2    Gordon, S.3
  • 21
    • 0029584593 scopus 로고
    • Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?
    • Kastner, P., Mark, M., and Chambon, P. (1995) Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life? Cell 83:859-869.
    • (1995) Cell , vol.83 , pp. 859-869
    • Kastner, P.1    Mark, M.2    Chambon, P.3
  • 22
    • 0019404024 scopus 로고
    • The role of morphogenetic cell death during abnormal limb-bud outgrowth in mice heterozygous for the dominant mutation Hemimelia extra toe (Hmx)
    • Knudsen, T.B., and Kochhar, D.M. (1981) The role of morphogenetic cell death during abnormal limb-bud outgrowth in mice heterozygous for the dominant mutation Hemimelia extra toe (Hmx) J. Embryol. Exp. Morphol. 65:289-307.
    • (1981) J. Embryol. Exp. Morphol. , vol.65 , pp. 289-307
    • Knudsen, T.B.1    Kochhar, D.M.2
  • 23
    • 0015785215 scopus 로고
    • Limb development in mouse embryos: I. Analysis of teratogenic effects of retinoic acid
    • Kochhar, D.M. (1973) Limb development in mouse embryos: I. Analysis of teratogenic effects of retinoic acid. Teratology 7:289-298.
    • (1973) Teratology , vol.7 , pp. 289-298
    • Kochhar, D.M.1
  • 24
    • 0003229639 scopus 로고
    • Abnormal organogenesis in limbs
    • Wilson, J.G. and Fraser, F.C. (eds). New York: Plenum Press
    • Kochhar, D.M. (1977) Abnormal organogenesis in limbs. In: "Handbook of Teratology," Wilson, J.G. and Fraser, F.C. (eds). New York: Plenum Press, pp 453-479.
    • (1977) Handbook of Teratology , pp. 453-479
    • Kochhar, D.M.1
  • 25
    • 0021592919 scopus 로고
    • Comparative teratogenic activities of two retinoids: Effects on palate and limb development
    • Kochhar, D.M., Penner, J.D., and Tellone, C.I. (1984) Comparative teratogenic activities of two retinoids: effects on palate and limb development. Teratogenesis Carcinog. Mutagen. 4:377-387.
    • (1984) Teratogenesis Carcinog. Mutagen. , vol.4 , pp. 377-387
    • Kochhar, D.M.1    Penner, J.D.2    Tellone, C.I.3
  • 26
    • 0027754637 scopus 로고
    • Evidence that retinoic acid-induced apoptosis in the mouse limb bud core mesenchymal cells is gene-mediated
    • Kochhar, D.M., Jiang, H., Harnish, D.C., and Soprano, D.R. (1993) Evidence that retinoic acid-induced apoptosis in the mouse limb bud core mesenchymal cells is gene-mediated. Prog. Clin. Biol. Res. 383B:815-825.
    • (1993) Prog. Clin. Biol. Res. , vol.383 B , pp. 815-825
    • Kochhar, D.M.1    Jiang, H.2    Harnish, D.C.3    Soprano, D.R.4
  • 28
    • 0026069580 scopus 로고
    • Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid
    • Leroy, P., Krust, A., Zelent, A., Mendelsohn, C., Gamier, J.P., Kastner, P., Dierich, A., Chambon, P. (1991) Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid. EMBO J. 10:59-69.
    • (1991) EMBO J. , vol.10 , pp. 59-69
    • Leroy, P.1    Krust, A.2    Zelent, A.3    Mendelsohn, C.4    Gamier, J.P.5    Kastner, P.6    Dierich, A.7    Chambon, P.8
  • 30
    • 0029118396 scopus 로고
    • Mice lacking all forms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid
    • Luo, J., Pasceri, P., Conlon, R.A., Rossant, J., Giguere, V. (1995) Mice lacking all forms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid. Mech. Dev. 53:61-71.
    • (1995) Mech. Dev. , vol.53 , pp. 61-71
    • Luo, J.1    Pasceri, P.2    Conlon, R.A.3    Rossant, J.4    Giguere, V.5
  • 31
    • 0025979545 scopus 로고
    • The homeobox gene Hox7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro
    • Mackenzie, A., Leeming, G.L., Jowette, A.K., Ferguson, M.W.J., and Sharpe, P.T. (1991) The homeobox gene Hox7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro. Development 111:269-285.
    • (1991) Development , vol.111 , pp. 269-285
    • Mackenzie, A.1    Leeming, G.L.2    Jowette, A.K.3    Ferguson, M.W.J.4    Sharpe, P.T.5
  • 32
    • 0026093858 scopus 로고
    • Developmental analysis of the retinoic acid-inducible RAR-beta 2 promoter in transgenic animals
    • Mendelsohn, C., Ruberte, E., LeMeur, M., Morriss-Kay, G., and Chambon, P. (1991) Developmental analysis of the retinoic acid-inducible RAR-beta 2 promoter in transgenic animals. Development 113:723-734.
    • (1991) Development , vol.113 , pp. 723-734
    • Mendelsohn, C.1    Ruberte, E.2    LeMeur, M.3    Morriss-Kay, G.4    Chambon, P.5
  • 35
    • 0011161191 scopus 로고
    • Mechanisms of cardiac morphogenesis and teratogenesis
    • Pexieder, T. (ed). New York: Raven Press
    • Ojeda, J.L., and Hurle, J.M. (1981) Mechanisms of cardiac morphogenesis and teratogenesis. In: "Perspectives in Cardiovascular Research," Vol. 5, Pexieder, T. (ed). New York: Raven Press, pp 101-113.
    • (1981) Perspectives in Cardiovascular Research , vol.5 , pp. 101-113
    • Ojeda, J.L.1    Hurle, J.M.2
  • 36
    • 0024452548 scopus 로고
    • Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis
    • Robert, B., Sassoon, D., Jacq, B., Gehring, W., and Buckingh, M.M. (1989) Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis. EMBO J. 8:91-100.
    • (1989) EMBO J. , vol.8 , pp. 91-100
    • Robert, B.1    Sassoon, D.2    Jacq, B.3    Gehring, W.4    Buckingh, M.M.5
  • 37
    • 0017353175 scopus 로고
    • The effects of the Dh gene on limb morphogenesis in the mouse
    • Rooze, M.A. (1977) The effects of the Dh gene on limb morphogenesis in the mouse. Birth Defects 13:69-95.
    • (1977) Birth Defects , vol.13 , pp. 69-95
    • Rooze, M.A.1
  • 38
    • 0026055409 scopus 로고
    • Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis
    • Rossant, J., Zirngibl, R., Cado, D., Shago, M., and Giguere, V. (1991) Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis. Genes Dev. 5:1333-1344.
    • (1991) Genes Dev. , vol.5 , pp. 1333-1344
    • Rossant, J.1    Zirngibl, R.2    Cado, D.3    Shago, M.4    Giguere, V.5
  • 39
    • 0028124265 scopus 로고
    • Formation of extra digits in the interdigital spaces of the chick leg bud is not preceded by changes in the expression of the Msx and Hoxd genes
    • Berl.
    • Ros, M.A., Macias, D., Fallon, J.F., and Hurle, J.M. (1994) Formation of extra digits in the interdigital spaces of the chick leg bud is not preceded by changes in the expression of the Msx and Hoxd genes. Anat. Embryol. (Berl.) 190:375-382.
    • (1994) Anat. Embryol. , vol.190 , pp. 375-382
    • Ros, M.A.1    Macias, D.2    Fallon, J.F.3    Hurle, J.M.4
  • 41
    • 0027501673 scopus 로고
    • Detection of messenger RNA by in situ hybridization
    • Sassoon, D., and Rosenthal, N. (1993) Detection of messenger RNA by in situ hybridization. Methods Enzymol. 225:384-404.
    • (1993) Methods Enzymol. , vol.225 , pp. 384-404
    • Sassoon, D.1    Rosenthal, N.2
  • 42
    • 0007268771 scopus 로고
    • The influence of oral vitamin A doses on interdigital necrosis in the limb bud of the rat
    • Schweichel, J.U. (1971) The influence of oral vitamin A doses on interdigital necrosis in the limb bud of the rat. Teratology 4:501.
    • (1971) Teratology , vol.4 , pp. 501
    • Schweichel, J.U.1
  • 43
    • 0026489523 scopus 로고
    • Vertebrate homeobox gene nomenclature
    • Scott, W. (1992) Vertebrate homeobox gene nomenclature. Cell 71:551-553.
    • (1992) Cell , vol.71 , pp. 551-553
    • Scott, W.1
  • 44
    • 0027996947 scopus 로고
    • Endogenous status of retinoids and their cytosolic binding proteins in limb buds of chick vs. mouse embryos
    • Scott, W.J., Walter, R., Tzimas, G., Sass, J.O., Nau, H., and Collins, M.D. (1994) Endogenous status of retinoids and their cytosolic binding proteins in limb buds of chick vs. mouse embryos. Dev. Biol. 165:397-409.
    • (1994) Dev. Biol. , vol.165 , pp. 397-409
    • Scott, W.J.1    Walter, R.2    Tzimas, G.3    Sass, J.O.4    Nau, H.5    Collins, M.D.6
  • 45
    • 0020042739 scopus 로고
    • Cell death in the mammalian visual system during normal development. I. Retinal ganglion cells
    • Sengelaub, D.R., and Finlay, B.L. (1982) Cell death in the mammalian visual system during normal development. I. Retinal ganglion cells. J. Comp. Neurol. 204:311-317.
    • (1982) J. Comp. Neurol. , vol.204 , pp. 311-317
    • Sengelaub, D.R.1    Finlay, B.L.2
  • 46
    • 0029588405 scopus 로고
    • Mouse embryos lacking RXR alpha are resistant to retinoic acid-induced limb defects
    • Sucov, H.M., Izpisua-Belmonte, J.C., Ganan, Y., and Evans, R.M. (1995) Mouse embryos lacking RXR alpha are resistant to retinoic acid-induced limb defects. Development 121:3997-4003.
    • (1995) Development , vol.121 , pp. 3997-4003
    • Sucov, H.M.1    Izpisua-Belmonte, J.C.2    Ganan, Y.3    Evans, R.M.4
  • 47
    • 0001822333 scopus 로고
    • Teratogenicity of the retinoids
    • Sauiat, J.H. (ed). Basel: Karger
    • Sulik, K.K., and Alles, A.J. (1991) Teratogenicity of the retinoids. In: "Retinoids: 10 Years On," Sauiat, J.H. (ed). Basel: Karger, pp 282-295.
    • (1991) Retinoids: 10 Years On , pp. 282-295
    • Sulik, K.K.1    Alles, A.J.2
  • 48
    • 0023782911 scopus 로고
    • Retinoic acid-induced limb malformations resulting from apical ectodermal ridge cell death
    • Sulik, K.K., and Dehart, D.B. (1988) Retinoic acid-induced limb malformations resulting from apical ectodermal ridge cell death. Teratology 37:527-537.
    • (1988) Teratology , vol.37 , pp. 527-537
    • Sulik, K.K.1    Dehart, D.B.2
  • 49
    • 0023761040 scopus 로고
    • Teratogens and craniofacial malformations: Relationships to cell death
    • Sulik, K.K., Cook, C.S., and Webster, W.S. (1988) Teratogens and craniofacial malformations: relationships to cell death. Development 103:213-232.
    • (1988) Development , vol.103 , pp. 213-232
    • Sulik, K.K.1    Cook, C.S.2    Webster, W.S.3
  • 51
    • 0025881362 scopus 로고
    • Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development
    • Tabin, C.J. (1991) Retinoids, homeoboxes, and growth factors: toward molecular models for limb development. Cell 66:199-217.
    • (1991) Cell , vol.66 , pp. 199-217
    • Tabin, C.J.1
  • 52
    • 0023193801 scopus 로고
    • Identification and spatial distribution of retinoids in the developing chick limb bud
    • Thaller, C., and Eichele, G. (1987) Identification and spatial distribution of retinoids in the developing chick limb bud. Nature 327:625-628.
    • (1987) Nature , vol.327 , pp. 625-628
    • Thaller, C.1    Eichele, G.2
  • 53
    • 0020316590 scopus 로고
    • Local application of retinoic acid to the limb bud mimics the action of the polarizing region
    • Tickle, C., Alberts, B.M., Wolpert, L., and Lee, J. (1982) Local application of retinoic acid to the limb bud mimics the action of the polarizing region. Nature 296:544-565.
    • (1982) Nature , vol.296 , pp. 544-565
    • Tickle, C.1    Alberts, B.M.2    Wolpert, L.3    Lee, J.4
  • 54
    • 0021815338 scopus 로고
    • A quantitative analysis of the effect of all-trans retinoic acid on the pattern of chick wing development
    • Tickle, C., Lee, J., and Eichele, G. (1985) A quantitative analysis of the effect of all-trans retinoic acid on the pattern of chick wing development. Dev. Biol. 109:82-95.
    • (1985) Dev. Biol. , vol.109 , pp. 82-95
    • Tickle, C.1    Lee, J.2    Eichele, G.3
  • 55
    • 0020324761 scopus 로고
    • The epithelial-mesenchymal interface of the male rat mullerian duct: Loss of basement membrane integrity and ductal regression
    • Trelstad, R.L., Hayashi, A., Hayashi, K., and Donahoe, P.K. (1982) The epithelial-mesenchymal interface of the male rat mullerian duct: loss of basement membrane integrity and ductal regression. Dev. Bio. 92:27-40.
    • (1982) Dev. Bio. , vol.92 , pp. 27-40
    • Trelstad, R.L.1    Hayashi, A.2    Hayashi, K.3    Donahoe, P.K.4
  • 57
    • 0028543659 scopus 로고
    • Apoptotic cell death in the limb and its relationship to pattern formation
    • Zakeri, Z.F., and Ahuja, H.S. (1994) Apoptotic cell death in the limb and its relationship to pattern formation. Biochem. Cell. Biol. 72:603-613.
    • (1994) Biochem. Cell. Biol. , vol.72 , pp. 603-613
    • Zakeri, Z.F.1    Ahuja, H.S.2
  • 58
    • 0027419446 scopus 로고
    • Delayed internucleosomal DNA fragmentation in programmed cell death
    • Zakeri, Z.F., Quaglino, D., Latham, T., and Lockshin, R. (1993) Delayed internucleosomal DNA fragmentation in programmed cell death. FASEB J. 7:470-478.
    • (1993) FASEB J. , vol.7 , pp. 470-478
    • Zakeri, Z.F.1    Quaglino, D.2    Latham, T.3    Lockshin, R.4
  • 59
    • 0028040714 scopus 로고
    • Apoptotic cell death in the mouse limb and its suppression in the Hammertoe mutant
    • Zakeri, Z.F., Quaglino, D., and Ahuja, H.S. (1994) Apoptotic cell death in the mouse limb and its suppression in the Hammertoe mutant. Dev. Biol. 165:294-297.
    • (1994) Dev. Biol. , vol.165 , pp. 294-297
    • Zakeri, Z.F.1    Quaglino, D.2    Ahuja, H.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.