Automated fed-batch fermentation with feed-back controls based on dissolved oxygen (DO) and pH for production of DNA vaccines

Journal of Industrial Microbiology and Biotechnology

Volumn 18, Issue 1, 1997, Pages 43-48

  Chen, W ^a,b   Graham, C ^a   Ciccarelli, R B ^a  

^a Apollon   (United States)

^b IMMUNOMEDICS INC   (United States)

Author keywords

DNA vaccines; E. coli plasmid DNA; Fed batch fermentation; Feed back control

Indexed keywords

DNA VACCINE; OXYGEN;

ARTICLE; AUTOMATION; BACTERIAL GROWTH; CONTROLLED STUDY; DNA SYNTHESIS; ESCHERICHIA COLI; FERMENTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PLASMID;

ACETIC ACID; AUTOMATIC DATA PROCESSING; BACTERIOLOGICAL TECHNIQUES; BIOMASS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CULTURE MEDIA; DNA, BACTERIAL; DNA, SUPERHELICAL; ELECTROPHORESIS, AGAR GEL; ESCHERICHIA COLI; FERMENTATION; GLUCOSE; HYDROGEN-ION CONCENTRATION; OXYGEN; PLASMIDS; VACCINES, DNA;

EID: 0030934349     PISSN: 13675435     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jim.2900355     Document Type: Article

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