Blood cortisol and dehydroepiandrosterone sulphate (DHEAS) levels and CD4 T cell counts in HIV infection

Clinical and Experimental Rheumatology

Volumn 15, Issue 1, 1997, Pages 87-90

  De La Torre, B ^a   Von Krogh, G ^b   Svensson, M ^b   Holmberg, V ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c STOCKHOLM SÖDER HOSPITAL   (Sweden)

Author keywords

CD4 T cells; cortisol; dehydroepiandrosterone sulphate; HIV infection

Indexed keywords

CD4 ANTIGEN; HYDROCORTISONE; PRASTERONE SULFATE;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; HORMONE BLOOD LEVEL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; PRIORITY JOURNAL; T LYMPHOCYTE;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; DEHYDROEPIANDROSTERONE SULFATE; FEMALE; HIV INFECTIONS; HUMANS; HYDROCORTISONE; LYMPHOCYTE COUNT; MALE; MIDDLE AGED;

EID: 0030934266     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. FAUCI AS, LANE HC: The acquired immunodeficiency syndrome (AIDS). In: WILSSON JD, BRAWUNWALD E, ISSELBACKER KJ, PETERSDORF RG, MARTIN JB, FAUCI AS, ROOF RK (Eds.): Harrison's Principles of Internal Medicine, 12th ed. McGraw-Hill, Inc., 1991; 1402-10.
2. DE LA TORRE B: Psychoendocrinologic mechanisms of life stress. Stress Medicine 1994; 10: 107-14.
3. NOTT KH, VEDHARA K, SPICKETT GP: Psychology, immunology, and HIV. Psychoneuroendocrinology 1995; 20: 451-74.
4. KAPLAN RM, ANDERSON JP, PATTERSON TL, MCCUTCHAN JA, WEINRICH D, HEATON RK, ATKINSON JH, THAL L, CHANDLER J, GRANT I and the HNRC GROUP: Validity of the quality of well-being scale for persons with human immunodeficiency virus infection. Psychosomatic Med 1995; 57: 138-47.
5. PAKENHAM KI, DADDS MR, TERRY DJ: Adaptive demands along the HIV disease continuum. Soc Sci Med 1996; 42: 245-56.
6. ROOK GAW, HERNANDEZ-PANDO R, LIGHTMAN SL: Hormones, peripherally activated prohormones and regulation of the Th1/Th2 balance. Immunology Today 1994; 15: 301-3.
7. JUNGER P, NAHOUL K, PELISSIER C, DOUGADOS M, ATHEA N, TRON F, BACH JF: A study of plasma androgen levels in systemic lupus erythematosus. Presse Med 1983; 12: 685-8.
8. LAHITA RG, BRADLOW H, GINZLER E, PANG S, NEW M: Low plasma androgens in women with systemic lupus erythematosus. Arthritis Rheum 1987; 30: 241-8.
9. HEDMAN M, NILSSON E, DE LA TORRE B: Low sulphoconjugated steroid hormone levels in systemic lupus erythematosus (SLE). Clin Exp Rheumatol 1989; 7: 83-8.
10. HEDMAN M, NILSSON E, DE LA TORRE B.: Low blood and synovial fluid levels of sulpho-conjugated steroids in rheumatoid arthritis. Clin Exp Rheumatol 1992; 10: 25-30.
11. DE LA TORRE B, HEDMAN M, NILSSON E, OLENSEN O, THÖRNER Å: Relationship between blood and joint tissue DHEAS levels in rheumatoid arthritis and osteoarthritis. Clin Exp Rheumatol 1993; 11: 597-601.
12. NILSSON E, DE LA TORRE B, HEDMAN M, GOOBAR J, THÖRNER Å: Blood dehydroepiandrosterone sulphate (DHEAS) levels in polymyalgia rheumatica/giant cell arteritis and primary fibromyalgia. Clin Exp Rheumatol 1994; 12: 415-17.
13. DE LA TORRE B, FRANSSON J, SCHEYNIUS A: Blood dehydroepiandrosterone sulphate (DHEAS) levels in pemphigoid/pemphigus and psoriasis. Clin Exp Rheumatol 1995; 13: 345-8.
14. FEHER G, FEHER T, MERETEY K: Interrelationship between the immunological and steroid hormone parameters in rheumatoid arthritis. Exp Clin Endocrinol 1986; 87: 32-8.
15. VILLETTE JM, BOURN P, DOINEL C, MANSOUR I, FIET J, BOUDOU P, DREUX C, ROUE R, DEBORD M, LEVI F: Circadian variations in plasma levels of hypophyseal, adrenocortical and testicular hormones in men infected with human immunodeficiency virus. J Clin Endocrinol Metab 1990; 70: 572-7.
16. CHRISTEFF N, GHARAKHANIAN S, THOBIE N, ROZENBAUN W, NUNEZ EA: Evidence of changes in adrenal and testicular steroids during HIV infection. J Acquired Immunodeficiency Syndromes 1992; 5: 841-6.
17. FINDLING JW, BUGGY BP, GILSON IH, BRUMMITT CHF, BERNSTEIN BM, RAFF H: Longitudinal evaluation of adrenocortical function in patients infected with the human immunodeficiency virus. J Clin Endocrinol Metabol 1994; 70: 1091-6.
18. WINIEWSKI TL, HILTON CHW, MORSE EV, SVEK F: The relationship of serum DHEAS and cortisol levels in human immunodeficiency virus-related illness. Am J Med Sc 1993; 305: 79-83.
19. MASON M: Effects of conjugated steroids on enzymes. In: FISHMAN HW (Ed.): Metabolic Conjugation and Metabolic Hydrolysis, Academic Press, New York, 1970; 121-56.
20. DE LA TORRE B: Quantitative clinical studies on adrenocortical and testicular steroids in adult human males (Dissertation), Stockholm, Sweden, 1982; 1-44.
21. MEIKLE AW, DORCHURCK RW, ARANEO BA, STRINGHAM JD, EVANS TG, SPRUANCE SL, DAYNES RA: The presence of dehydroepiandrosterone-specific receptor binding complex in murine T cells. J Steroid Biochem Molec Biol 1992; 42; 293-304.
22. BROWNE ES, PORTER JR, CORREA G, ABADIE J SVEK F: Dehydroepiandrosterone regulation of the hepatic glucocorticoid receptor in the Zucker rat. The Obesity Research Programme. Steroid Biochem Molec Biol 1993; 45: 517-24.
23. SCHWARTZ AG, PASHKOL L, WHITECOMBE RW: Inhibition of tumor development by DHA and related steroids. Toxicol Pathol 1986; 14: 357-62.
24. COLEMAN DL, LEITER EH, SCHWlZER RW: Therapeutic effects of dehydroepiandrosterone in diabetic mice. Diabetes 1982; 31: 830-3.
25. JANG J-Y, SCHWARTZ A, HENDERSON EE: Inhibition of HIV-1 latency reactivation by dehydroepiandrosterone (DHEA) and an analogue of DHEA. Aids Res and Hum Retrovirus 1993; 9: 747-24.
26. DYNER TS, LANG W, GEAGA J, GALUB A, STITES D, WINGER E, GALMARINI E, MASTERSON J, JAKOBSON MA: An open-label trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV-disease. J Acquired Immune Deficiency Syndromes 1993; 6: 459-65.