Intragenic Tsc2 somatic mutations as Knudson's second hit in spontaneous and chemically induced renal carcinomas in the Eker rat model

Japanese Journal of Cancer Research

Volumn 88, Issue 3, 1997, Pages 254-261

  Kobayashi, Toshiyuki ^a   Urakami, Shinji ^a   Hirayama, Youko ^a   Yamamoto, Toshiki ^a   Nishizawa, Masae ^a   Takahara, Tomoko ^a   Kubo, Yoshiaki ^a   Hino, Okio ^a  

^a CANCER INSTITUTE   (Japan)

Author keywords

Eker rat; Hereditary cancer; Tuberous sclerosis (Tsc2) gene; Tumor suppressor gene; Two hit

Indexed keywords

RNA DIRECTED DNA POLYMERASE;

ANIMAL TISSUE; ARTICLE; CELL LINE; DNA SEQUENCE; EXON; GENE DELETION; GENE DUPLICATION; GENE MUTATION; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; KIDNEY CARCINOMA; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; SINGLE STRAND CONFORMATION POLYMORPHISM; SOMATIC MUTATION; TUBEROUS SCLEROSIS;

EID: 0030934101     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1997.tb00375.x     Document Type: Article

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