Modulation by aspartate of ischemia/reperfusion-induced oxidative stress in rat liver

Experimental and Molecular Medicine

Volumn 29, Issue 1, 1997, Pages 19-23

  Park, Yeong Chul ^a   Oh, Se In ^a   Park, Yong Hoon ^a   Park, Sang Chul ^a  

^a Seoul National University   (South Korea)

Author keywords

Aspartate; Ischemia reperfusion injury; Oxidative stress; Rat liver; Xanthine oxidase

Indexed keywords

ASPARTIC ACID; LIPID; THIOBARBITURIC ACID REACTIVE SUBSTANCE; XANTHINE DEHYDROGENASE; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIPID PEROXIDATION; LIVER ISCHEMIA; LIVER METABOLISM; MALE; METABOLIC REGULATION; NONHUMAN; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; RAT; REPERFUSION INJURY;

ANIMALIA;

EID: 0030933726     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.1997.3     Document Type: Article

References (20)

1. Ballard, F. J. (1971) Regulation of gluconeogenesis during exposure of young rats to hypoxic conditions. Biochem. J. 121: 169-178
2. Deaciuc, I. V., D'Souza, N. B., Lang, C. H. and Spizer, J. S. (1992) Effects of acute alcohol intoxication on gluconeogenesis and its hormonal responsiveness in isolated, perfused rat liver. Biochem. Pharmacol. 44: 1617-1624
3. Engerson, T. D., McKelvey, T. G., Rhyne, D. B., Boggio, E. B., Snyder, S. J. and Jones, H. P. (1987) Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues. J. Clin. Invest. 79: 424-431
4. Esterbauer, H. and Cheeseman, K. H. (1990) Determination of aldehydic li[pid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 186: 407-423
5. Faller, J. and Fox, I. H. (1982) Ethanol-induced hyperuricemia. Evidence for increased urate production by activation of adenine dinucleotide turnover. N. Engl. J. Med. 307: 1598-1602
6. Kato, S., Kawase, T., Alderman, J., Inatomi, N. and Lieber, C. S. (1990) Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats. Gasteroenterology 98: 203-210
7. Khan, S. and O'Brien, P. J. (1995) Modulating hypoxia-induced hepatocyte injury by affecting intracellular redox state. Biochim Biophys. Acta 1269: 153-161
8. Kamiike W., Watanabe F., Hashimoto T., Tagawa K., Ikeda Y., Nakao K. and Kawashima Y. (1982) Changes in cellular levels of ATP and its catabolites in ischemic rat liver J. Biochem. 91: 1349-1356
9. Lowry, O. H., Rosenbrough, A. L., Farr, A. L. and Randall, R. J. (1951) Protein measurement with Folin phenol reagent. J. Biol. Chem. 193: 265-275
10. Malis, C. D. and Bonventre, J. V. (1986) Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondria! damage. J. Biol. Chem. 261(30): 14201-8
11. Manning, A. S., Coltart, D. J. and Hearse, D. J. (1984) Ischemia and reperfusion-induced arrythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol. Circ. Res. 55: 545-548
12. Marubayashi, S., Dohi, K., Yamada K. and Kawasaki, T. (1991) Role of conversion of xanthine dehydrogenase to oxidase in ischemic rat liver cell injury. Surgery 110: 537-543
13. Park, S. C. (1993) Ethanol oxidation is accelerated by augmentation of malate-aspartate shuttle with aspartate. Korean J. Biochem. 25: 137-143
14. Park, Y. C. and Park, S. C. (1995) Reduction of oxidative stress by aspartate in the ethanol-perfused rat liver tissues. Korean J. Biochem. 27: 165-169
15. Park Y. C. Oh, S. I., Lee, S. L. and Park, S. C. (1996) Effects of amino acids on ethanol metabolism and oxidative stress in the ethanol-perfused rat liver. Korean Env. Mutagen Carcinogen 16: 13-18
16. Parks, D. A., Bulkley, G. B., Granger, D. N., and McCord, J. M. (1982) Ischemic injury in the cat small intestine: role of superoxide radicals. Gastroenterology 82: 9-15
17. Reinke, L. A., Belinsky, S. A., Kauffman, F. C., Evans, R. K. and Thruman, R. G. (1982) Regulation of NADPH- and NADH-dependent mixed-function oxidation in perfused livers. Biochem. Pharmacol. 31: 1621-1628
18. Roy, R. S. and McCord, J. M. (1983) Superoxide and ischemia: conversion of xanthine dehydrogenase to xanthine oxidase. In Proceeding of the Third International Conference on superoxide and superoxide dismutase (Greenwals, R and Cohen, G, eds.), pp. 145-153, Elsevier/North Holland Biomedical Press, New York
19. Stein, H. J., Hinder R. A. and Ooshuizen, M. M. (1990) Gastric mucosal injury caused by hemorrhagic shock and reperfusion: protective role of the antioxidant glutathione. Surgery 108: 467-74
20. 2-dependent (type O) forms of rat liver xanthine dehydrogenase. Arch. Biochem. Biophys. 172: 354-364