Expression of MDR1/p-glycoprotein and multidrug resistance-associated protein in childhood solid tumours

Virchows Archiv

Volumn 430, Issue 2, 1997, Pages 99-105

  Oda, Y ^a   Rose I ^a   Radig, K ^a   Wagemann, W ^a   Mittler, U ^a   Roessner, A ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Multidrug resistance; Nephroblastoma; Neuroblastoma; P glycoprotein; Reverse transcriptase polymerase chain reaction

Indexed keywords

GLYCOPROTEIN P; MESSENGER RNA; MONOCLONAL ANTIBODY;

ADRENAL CORTEX CARCINOMA; ARTICLE; BENIGN TUMOR; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; DOT HYBRIDIZATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MULTIDRUG RESISTANCE; NEPHROBLASTOMA; NEUROBLASTOMA; NEWBORN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHABDOMYOSARCOMA; SCHOOL CHILD; SOLID TUMOR;

EID: 0030933658     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01008030     Document Type: Article

References (37)

1. Akiyama S, Fojo A, Hanover JA, Pastan I, Gottesman MM (1985) Isolation and genetic characterization of human KB cell lines resistant to multiple drugs. Somatic Cell Genet 11:117-126
2. Barrand MA, Heppel-Parton AC, Wright KA, Rabbitts PH, Twentyman PR (1994) A 190-kilodalton protein overexpression in non-p-glycoprotein-containing multidrug-resistant cells and its relationship to the MRP gene. J Natl Cancer Int 86: 110-117
3. Bates SE, Shieh CY, Tsokos M (1991) Expression of mdr1/P-glycoprotein in human neuroblastoma. Am J Pathol 139:305-315
4. Benard J, Bourhis J, Riou G (1991) Activation of N-myc oncogene and associated genes to chemoresistance, prognostic value for neuroblastoma. Bull Cancer (Paris) 78:91-97
5. Benard J, Bourhis J, de-Vathaire F, Ferrandis E, Terrier-Lacombe MJ, Lemerle J, Riou G, Hartmann O (1994) Prognostic value of MDR1 gene expression in neuroblastoma: results of a multivariante analysis. Prog Clin Biol Res 385:111-16
6. Bordow SB, Haber M, Madafiglio J, Cheung B, Marshall GM, Norris MD (1994) Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma. Cancer Res 54:5036-5040
7. Bourhis J, Benard J, Hartmann O, Boccon-Gibod L, Lemerle J, Riou G (1989) Correlation of MDR1 gene expression with chemotherapy in neuroblastoma. J Natl Cancer Inst 81:1401-1405
8. Brophy NA, Marie JP, Rojas VA, Warnke RA, McFall PJ, Smith SD, Sikic BI (1994) Mdr1 gene expression in childhood acute lymphoblastic leukemias and lymphomas: A critical evaluation by four techniques. Leukemia 8:327-335
9. Chan HSL, Haddad G, Thorner PS, DeBoer G, Lin YP, Ondrusek N, Yeger H, Ling V (1990) P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma. N Engl J Med 325:1608-1614
10. Chen G, Jaffrezou J-P, Fleming WH, Duran GE, Sikic BI (1994) Prevalence of multidrug resistance related to activation of the mdr1 gene in human sarcoma mutants derived by single-step doxorubicin selection. Cancer Res 54:4980-4987
11. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
12. Cole SPC, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AMV, Deeley RG (1992) Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 258:1650-1654
13. Cordon-Cardo C, O'Brien JP, Boccia J, Casals D, Bertino Jr, Melamed MR (1990) Expression of the multidrug resistance gene product (p-glycoprotein) in human normal and tumor tissues. J Histochem Cytochem 38:1277-1287
14. Corrias MV, Cornaglia-Ferraris P, Di-Martino D, Stenger AM, Lanino E, Boni L, Tonini GP (1990) Expression of multiple drug resistance gene, MDR1, and N-myc oncogene in Italian population of human neuroblastoma patients. Anticancer Res 10:897-902
15. D'Angio GJ, Breslow N, Beckwith B, Evans A, Baum E, De-Limier A, Fernbach D, Hrabovsky E, Jones B, Kelalis P, Othersen B, Tefft M, Thomas PRM (1989) Treatment of Wilms' tumor: Results of the third national Wilms' tumor study. Cancer 64:349-360
16. Dietel M (1991) What's new in cytostatic drug resistance and pathology. Pathol Res Pract 187:892-905
17. Dietel M (1993) Meeting report. Second international symposium on cytostatic drug resistance. Cancer Res 53:2683-2688
18. Evans AE, D'Andio GJ, Randolph JA (1971) A proposed staging for children with neuroblastoma. Cancer 27:374-378
19. Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MM, Pastan I (1987) Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci USA 84:265-269
20. Futscher BW, Abbaszadegan Mr, Domann F, Dalton WS (1994) Analysis of MRP mRNA in mitoxantrone-selected. multidrug-resistant human tumor cells. Biochem Pharmacol 47:1601-1606
21. Gekeler V, Beck J, Noller A, Wilisch A, Frese G, Neumann M, Handgretinger R, Ehninger G, Probst H, Niethammer D (1994) Drug-induced changes in the expression of MDR-associated genes: investigations on cultured cell lines and chemotherapeutically treated leukemias. Ann Hematol [Suppl] 69: 519-524
22. Goldstein LJ, Galski H, Fojo A, Willingham M, Lai S-L, Gazdar A, Priker R, Green A, Crist W, Brodeur GM, Lieher M, Cossman J, Gottesman MM, Pastan I (1989) Expression of a multidrug resistance gene in human cancers. J Natl Cancer Inst 81:116-124
23. Goldstein LJ, Fojo AT, Ueda K, Crist W, Green A, Brodeur G, Pastan I, Gottesman MM (1990) Expression of the multidrug resistance, MDR1, gene in neuroblastoma. J Clin Oncol 8: 128-136
24. Hughes M, Marsden HB, Palmer MK (1974) Histologie patterns of neuroblastoma related to prognosis and clinical staging. Cancer 34:1706-1711
25. Jereb B, Tournade MF, Jemerle J, Voute PA, Delemarre JF, Ahstrom L, Flamant R, Gerard-Marchant R, Sandstedt B (1980) Lymph node invasion and prognosis in nephroblastoma. Cancer 45:1632-1636
26. Juliano R, Ling A (1976) A surface glycoprotein modulation drug permeability in Chinese hamster ovarian cell mutants. Biochim Biophys Acta 455:152-162
27. Kandel RA, Campbell S, Noble-Topham S, Bell R, Andrulis IL (1995) Correlation of p-glycoprotein by immunohistochemistry with mdr-1 mRNA levels in osteosarcomas. Pilot study. Diagn Mol Pathol 4:59-65
28. Nakagawara A, Kadomatsu K, Sato S, Kohno K, Takano H, Akazawa K, Nose Y, Kuwano M (1990) Inverse correlation between expression of multidrug resistance gene and N-myc oncogene in human neuroblastoma. Cancer Res 50:3043-3047
29. Noonan K, Beck C, Holtzmayer T, Chin JE, Wunder JS, Andrulis IL, Gazdar AF, Willman CL, Griffith B, Von Hoff DD, Roninson IB (1990) Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction. Proc Natl Acad Sci USA 87:7160-7164
30. McDowell H, Peuchmaur M, Dominici C, Flamant F (1993) Multidrug resistance gene transcript level, and p-glycoprotein expression in paediatric malignant mesenchymal tumours. Anticancer Res 13:1863-1866
31. Pastan I, Gottesman M (1987) Multidrug resistance in human cancer. N Engl J Med 316:1388-1393
32. Ramani P, Dewchand H (1995) Expression of mdr1/P-glycoprotein and p110 in neuroblastoma. J Pathol 175:13-22
33. Schmidt D, Harms D (1983) Histology and prognosis of nephroblastoma - with particular reference to special variants. Klin Padiatr 195:214-221
34. Shen DW, Fojo A, Chin JE, Roninson IB, Richert N, Pastan I, Gottesman MM (1986) Human multidrug-resistant cell lines: Increased mdr1 expression can precede gene amplification. Science 232:643-645
35. Sugawara I, Arai T, Yamashita T, Yoshida A, Masunaga A, Itoyama S (1994) Expression of multidrug resistance-associated protein (MRP) in anaplastic carcinoma of the thyroid. Cancer Lett 82:185-188
36. Ueda K, Cornwell MM, Gottesman MM, Pastan I, Roninson IB, Ling V, Riordan JR (1986) The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein. Biochem Biophys Res Commun 141:956-962
37. Ueda K, Clark DP, Chen C, Roninson IB, Gottesman MM, Pastan I (1987) The human multidrug resistance (mdr1) gene: cDNA cloning and tanscription initiation. J Biol Chem 262:505-508