메뉴 건너뛰기




Volumn 1, Issue 4, 1997, Pages 193-200

Genetic polymorphisms in alcohol metabolizing enzymes as related to sensitivity to alcohol-induced health effects

Author keywords

Alcohol; ALDH2; Cytochrome P450 2E1; Genotype; Health effects

Indexed keywords

ALDEHYDE DEHYDROGENASE; CYTOCHROME P450;

EID: 0030933531     PISSN: 1342078X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02931216     Document Type: Article
Times cited : (10)

References (36)
  • 1
    • 0017406798 scopus 로고
    • Two aldehyde dehydrogenases from human liver. Isolation via affinity chromarography and characterizatio of the isozymes
    • Greenfield NJ, Pietruszko R. Two aldehyde dehydrogenases from human liver. Isolation via affinity chromarography and characterizatio of the isozymes. Biochim Biophys Acta 1977; 483: 35-45.
    • (1977) Biochim Biophys Acta , vol.483 , pp. 35-45
    • Greenfield, N.J.1    Pietruszko, R.2
  • 2
    • 0018891404 scopus 로고
    • Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: Isozyme variation and its possible role in alcohol intoxication
    • Harada S, Misawa S, Agarwal DP, Goedde HW. Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: Isozyme variation and its possible role in alcohol intoxication. Am J Hum Genet 1980; 32: 8-15.
    • (1980) Am J Hum Genet , vol.32 , pp. 8-15
    • Harada, S.1    Misawa, S.2    Agarwal, D.P.3    Goedde, H.W.4
  • 3
    • 0018881507 scopus 로고
    • Isozymes of alcohol dehydrogenase and aldehyde dehydrogenase in Japanese and their role in alcohol sensitivity
    • Harada S, Agarwal DP, Goedde HW. Isozymes of alcohol dehydrogenase and aldehyde dehydrogenase in Japanese and their role in alcohol sensitivity. Adv Exp Med Biol 1980; 39: 31-9.
    • (1980) Adv Exp Med Biol , vol.39 , pp. 31-39
    • Harada, S.1    Agarwal, D.P.2    Goedde, H.W.3
  • 4
    • 0026062622 scopus 로고
    • Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450 II E1 gene
    • Hayashi S, Watanabe J, Kawajiri K. Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450 II E1 gene J Biochem 1991; 110: 559-65.
    • (1991) J Biochem , vol.110 , pp. 559-565
    • Hayashi, S.1    Watanabe, J.2    Kawajiri, K.3
  • 5
    • 0016427486 scopus 로고
    • High blood acetaldehyde levels after ethanol administration. Difference between alcoholic and nonalcoholic subjects
    • Korsten MA, Matsuzaki S, Feinman L, Lieber CS. High blood acetaldehyde levels after ethanol administration. Difference between alcoholic and nonalcoholic subjects. N Engl J Med 1975; 292: 386-9.
    • (1975) N Engl J Med , vol.292 , pp. 386-389
    • Korsten, M.A.1    Matsuzaki, S.2    Feinman, L.3    Lieber, C.S.4
  • 6
    • 0016440832 scopus 로고
    • Alcoholism or acetaldehidism?
    • Raskin NH. Alcoholism or acetaldehidism? N Engl J Med 1975; 292: 422-3.
    • (1975) N Engl J Med , vol.292 , pp. 422-423
    • Raskin, N.H.1
  • 7
    • 0019306009 scopus 로고
    • Alcohol, protein metabolism and liver injury
    • Lieber CS. Alcohol, protein metabolism and liver injury. Gastroenterol 1980; 79: 373-90.
    • (1980) Gastroenterol , vol.79 , pp. 373-390
    • Lieber, C.S.1
  • 8
    • 0018342598 scopus 로고
    • Relationship between facial flushing and blood acetaldehyde levels after alcohol intake
    • Mizoi Y, Ijiri I, Tatsuno Y, et al. Relationship between facial flushing and blood acetaldehyde levels after alcohol intake. Pharmac Biochem Behav 1979; 10: 303-11.
    • (1979) Pharmac Biochem Behav , vol.10 , pp. 303-311
    • Mizoi, Y.1    Ijiri, I.2    Tatsuno, Y.3
  • 9
    • 0018741876 scopus 로고
    • The role of acetaldehyde in mediating reactivity to an acute dose of ethanol among different racial groups
    • Zeiner AR, Paredes A, Dix Christensen H. The role of acetaldehyde in mediating reactivity to an acute dose of ethanol among different racial groups. Alcoholism Clin Exp Res 1979; 3: 11-8.
    • (1979) Alcoholism Clin Exp Res , vol.3 , pp. 11-18
    • Zeiner, A.R.1    Paredes, A.2    Dix Christensen, H.3
  • 10
    • 0005350530 scopus 로고
    • Aldehyde dehydrogenase deficiency as cause of facial flushing reaction to alcohol in Japanese
    • Harada S, Agarwal DP, Goedde HW. Aldehyde dehydrogenase deficiency as cause of facial flushing reaction to alcohol in Japanese. Lancet 1981;ii:982.
    • (1981) Lancet , vol.2 , pp. 982
    • Harada, S.1    Agarwal, D.P.2    Goedde, H.W.3
  • 11
    • 0028256189 scopus 로고
    • Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes
    • Tsutsumi M, Wang JS, Takada A. Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes. Int Hepatol Commun 1994; 2: 135-8.
    • (1994) Int Hepatol Commun , vol.2 , pp. 135-138
    • Tsutsumi, M.1    Wang, J.S.2    Takada, A.3
  • 12
    • 0028145234 scopus 로고
    • Different regulation and expression of the human CYP2E1 gene due to Rsa I polymorphism in the 5′-flanking region
    • Watanabe J, Hayashi S, Kawajiri K. Different regulation and expression of the human CYP2E1 gene due to Rsa I polymorphism in the 5′-flanking region. J Biochem 1994; 116: 321-6.
    • (1994) J Biochem , vol.116 , pp. 321-326
    • Watanabe, J.1    Hayashi, S.2    Kawajiri, K.3
  • 13
    • 0025947090 scopus 로고
    • Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes
    • Enomoto N, Takase S, Takada N, Takada A. Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes. Hepatology 1991; 13: 1071-5.
    • (1991) Hepatology , vol.13 , pp. 1071-1075
    • Enomoto, N.1    Takase, S.2    Takada, N.3    Takada, A.4
  • 14
    • 0021269187 scopus 로고
    • Low Km ALDH isozyme and alcoholic liver injury
    • Yoshihara H, Sato N, Kamada T, Abe H. Low Km ALDH isozyme and alcoholic liver injury. Pharmac Biochem Behav 1983; 18 (Suppl. 1): 425-8.
    • (1983) Pharmac Biochem Behav , vol.18 , Issue.1 SUPPL. , pp. 425-428
    • Yoshihara, H.1    Sato, N.2    Kamada, T.3    Abe, H.4
  • 16
    • 0028177496 scopus 로고
    • Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in Chinese patients
    • Chao YC, Liou SR, Chung YY, et al. Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in Chinese patients. Hepatology 1994; 19: 360-6.
    • (1994) Hepatology , vol.19 , pp. 360-366
    • Chao, Y.C.1    Liou, S.R.2    Chung, Y.Y.3
  • 17
    • 0027943121 scopus 로고
    • Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease
    • Tsutsumi M, Takada A, Wang JS. Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease. Gastroenrerol 1994; 107: 1430-5.
    • (1994) Gastroenrerol , vol.107 , pp. 1430-1435
    • Tsutsumi, M.1    Takada, A.2    Wang, J.S.3
  • 18
    • 0029589352 scopus 로고
    • Genetic polymorphism of cytochrome P4502E1 and risk of alcoholic liver disease in Caucasians
    • Pirmohamed M, Kirteringham NR, Quest LJ, et al. Genetic polymorphism of cytochrome P4502E1 and risk of alcoholic liver disease in Caucasians. Pharmacogenet 1995; 5: 351-7.
    • (1995) Pharmacogenet , vol.5 , pp. 351-357
    • Pirmohamed, M.1    Kirteringham, N.R.2    Quest, L.J.3
  • 19
    • 0028211890 scopus 로고
    • Association between restriction fragment length polymorphism of the human cycochrome P450 2E1 gene and susceptibility to alcoholic liver cirrhosis
    • Maezawa Y, Yamauchi M, Toda G. Association between restriction fragment length polymorphism of the human cycochrome P450 2E1 gene and susceptibility to alcoholic liver cirrhosis. Am J Gatroenterol 1994; 89: 561-5.
    • (1994) Am J Gatroenterol , vol.89 , pp. 561-565
    • Maezawa, Y.1    Yamauchi, M.2    Toda, G.3
  • 20
    • 0028847431 scopus 로고
    • An investigation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a chinese population
    • Chao YC, Young TH, Chang WK, Tang HS, Hsu CT. An investigation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a chinese population. Hepatology 1995; 22: 1409-14.
    • (1995) Hepatology , vol.22 , pp. 1409-1414
    • Chao, Y.C.1    Young, T.H.2    Chang, W.K.3    Tang, H.S.4    Hsu, C.T.5
  • 22
    • 0025895356 scopus 로고
    • Genotyping of the aldehyde dehydrogenase 2 (ALDH2) gene using the polymerase chain reaction: Evidence for single point mutation in the ALDH2 gene of ALDH2 deficiency
    • Enomoto N, Takada A, Date T. Genotyping of the aldehyde dehydrogenase 2 (ALDH2) gene using the polymerase chain reaction: Evidence for single point mutation in the ALDH2 gene of ALDH2 deficiency. Gastroenterol Jpn 1991; 26: 440-7.
    • (1991) Gastroenterol Jpn , vol.26 , pp. 440-447
    • Enomoto, N.1    Takada, A.2    Date, T.3
  • 25
    • 0028561952 scopus 로고
    • Association among genotypes of aldehyde dehydrogenase 2 and alcohol consumption
    • Ishibashi T, Harada S, Tanimura S, Taguchi F. Association among genotypes of aldehyde dehydrogenase 2 and alcohol consumption. Jpn J Alcohol Drug Depend 1994; 29: 527-35.
    • (1994) Jpn J Alcohol Drug Depend , vol.29 , pp. 527-535
    • Ishibashi, T.1    Harada, S.2    Tanimura, S.3    Taguchi, F.4
  • 26
    • 0028048215 scopus 로고
    • Characterization of the three genotypes of low Km aldegyde dehydrogenase in a Japanese population
    • Takeshita T, Morimoto K, Mao X, Hashimoto T, Furuyama J. Characterization of the three genotypes of low Km aldegyde dehydrogenase in a Japanese population. Human Genet 1994; 94: 217-23.
    • (1994) Human Genet , vol.94 , pp. 217-223
    • Takeshita, T.1    Morimoto, K.2    Mao, X.3    Hashimoto, T.4    Furuyama, J.5
  • 27
    • 0020379998 scopus 로고
    • Ethanol-induced hyperuricemia. Evidence for increased urate production by activation of adenine nucleotide turnover
    • Faller J, Fox IH. Ethanol-induced hyperuricemia. Evidence for increased urate production by activation of adenine nucleotide turnover. N Eng J Med 1982; 307: 1598-602.
    • (1982) N Eng J Med , vol.307 , pp. 1598-1602
    • Faller, J.1    Fox, I.H.2
  • 28
    • 0020520557 scopus 로고
    • Drinking and its relation to smoking, BP, blood lipids, and uric acid
    • Gordon T, Kannel WB. Drinking and its relation to smoking, BP, blood lipids, and uric acid. Arch Intern Med 1983; 143: 1366-74.
    • (1983) Arch Intern Med , vol.143 , pp. 1366-1374
    • Gordon, T.1    Kannel, W.B.2
  • 29
    • 0023156644 scopus 로고
    • Alcohol consumption and hypertension
    • MacMahon S. Alcohol consumption and hypertension. Hypertension 1987; 9: 111-21.
    • (1987) Hypertension , vol.9 , pp. 111-121
    • MacMahon, S.1
  • 30
    • 8244253890 scopus 로고
    • Alcohol and hyperrension
    • Ueshima H. Alcohol and hyperrension. Jpn J Publ Health 1986; 33: 253-7.
    • (1986) Jpn J Publ Health , vol.33 , pp. 253-257
    • Ueshima, H.1
  • 31
    • 0019079965 scopus 로고
    • The association of plasma high-density lipoprotein cholesterol with dietary intake and alcohol consumption. The Lipid Research Clinics Program Prevalence Study
    • Ernst N, Fisher M, Smith W, et al. The association of plasma high-density lipoprotein cholesterol with dietary intake and alcohol consumption. The Lipid Research Clinics Program Prevalence Study. Circulation 1980; 62 (Suppl. IV): IV 41-52.
    • (1980) Circulation , vol.62 , Issue.4 SUPPL.
    • Ernst, N.1    Fisher, M.2    Smith, W.3
  • 32
    • 0023200901 scopus 로고
    • Longitudinal and secular trends in lipoprotein cholesterol measurements in a general population sample. The Framingham offspring study
    • Anderson KM, Wilson PWF, Garrison RJ, Castelli WP. Longitudinal and secular trends in lipoprotein cholesterol measurements in a general population sample. The Framingham offspring study. Atherosclerosis 1987; 68: 59-66.
    • (1987) Atherosclerosis , vol.68 , pp. 59-66
    • Anderson, K.M.1    Wilson, P.W.F.2    Garrison, R.J.3    Castelli, W.P.4
  • 33
    • 0025886595 scopus 로고
    • Elevations of serum angiotensin-converting enzyme and gamma-glutamyl transpeptidase activities in hypertensive drinkers
    • Yamada Y, Ishizaki M, Kido T, et al. Elevations of serum angiotensin-converting enzyme and gamma-glutamyl transpeptidase activities in hypertensive drinkers, J Hum Hypertens 1991; 5: 183-8.
    • (1991) J Hum Hypertens , vol.5 , pp. 183-188
    • Yamada, Y.1    Ishizaki, M.2    Kido, T.3
  • 34
    • 0028031996 scopus 로고
    • Serum gamma-glutamyl transpeptidase level and blood pressure in nondrinkers: A possible pathogenetic role of fatty liver in obesity-related hypertension
    • Ikai E, Honda R, Yamada Y. Serum gamma-glutamyl transpeptidase level and blood pressure in nondrinkers: A possible pathogenetic role of fatty liver in obesity-related hypertension. J Hum Hypertens 1994; 8: 95-100.
    • (1994) J Hum Hypertens , vol.8 , pp. 95-100
    • Ikai, E.1    Honda, R.2    Yamada, Y.3
  • 35
    • 0028910684 scopus 로고
    • Association between hepatic steatosis, insulin resistance and hyperinsulinaemia as related to hypertension in alcohol consumers and obese people
    • Ikai E, Ishizaki M, Suzuki Y, Ishida M, Noborizaka Y, Yamada Y. Association between hepatic steatosis, insulin resistance and hyperinsulinaemia as related to hypertension in alcohol consumers and obese people. J Hum Hypertens 1995; 9: 101-5.
    • (1995) J Hum Hypertens , vol.9 , pp. 101-105
    • Ikai, E.1    Ishizaki, M.2    Suzuki, Y.3    Ishida, M.4    Noborizaka, Y.5    Yamada, Y.6
  • 36
    • 0026325211 scopus 로고
    • Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration
    • Facchini F, Chen YDI, Hollenbech CB, et al. Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration. JAMA 1991; 266: 3008-11.
    • (1991) JAMA , vol.266 , pp. 3008-3011
    • Facchini, F.1    Chen, Y.D.I.2    Hollenbech, C.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.