Additive deficits in the choice accuracy of rats in the delayed non-matching to position task after cholinolytics and serotonergic lesions are non-mnemonic in nature

Psychopharmacology

Volumn 130, Issue 4, 1997, Pages 303-312

  Ruotsalainen, Sirja ^a   MacDonald, Ewen ^a   Miettinen, Riitta ^a   Puumala, Tarja ^a   Riekkinen Sr , Paavo ^a   Sirviö, Jouni ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

motor activity; muscarinic; nicotinic; rat; serotonergic; working memory

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; 5,7 DIHYDROXYTRYPTAMINE; HEXAMETHONIUM; MECAMYLAMINE; METHYLSCOPOLAMINE; MONOAMINE; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; SCOPOLAMINE; SEROTONIN;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CHOLINERGIC SYSTEM; CONTROLLED STUDY; CORPUS STRIATUM; FRONTAL CORTEX; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOTOR ACTIVITY; NONHUMAN; OCCIPITAL CORTEX; PARIETAL LOBE; PRIORITY JOURNAL; RAT; RESPONSE TIME; SEROTONIN BRAIN LEVEL; SEROTONINERGIC SYSTEM; SPATIAL MEMORY; TASK PERFORMANCE; WORKING MEMORY;

EID: 0030932478     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130050244     Document Type: Article

References (32)

1. Altman HJ, Ögren SO, Berman RF, Normile HJ (1989) The effects of p-chloroamphetamine, a depletor of brain serotonin, on the performance of rats in two types of positively reinforced complex spatial discrimination tasks. Behav Neural Biol 52:131-144
2. Andrews JS, Jansen JHM, Linders S, Princen A (1994) Effects of disrupting the cholinergic system on short-term spatial memory in rats. Psychopharmacology 115:485-494
3. Baumgarten HG, Klemm HP, Sievers J, Schlossberger HG (1982) Dihydroxytryptamines as tools to study the neurobiology of serotonin. Brain Res Bull 9:131-150
4. Buxton A, Callan OA, Blatt EJ, Wong EHF, Fontana DJ (1994) Cholinergic agents and delay-dependent performance in the rat. Pharmacol Biochem Behav 49:1067-1073
5. Cassel J-C, Jeltsch H (1995) Serotonergic modulation of cholinergic function in the central nervous system: cognitive implications. Neuroscience 69:1-41
6. Clarke PBS, Fibiger HC (1990) Reinforced alternation performance is impaired by muscarinic but not by nicotinic receptor blockade in rats. Behav Brain Res 36:203-207
7. Cole BJ, Klewer M, Jones GH, Stephens DN (1993) Contrasting effects of the competitive NMDA antagonist CPP and the noncompetitive NMDA antagonist MK 801 on performance of an operant delayed matching to position task in rats. Psychopharmacology 111:465-471
8. Dunnett SB (1990) Role of prefrontal cortex and striatal output systems in short-term memory deficits associated with ageing, basal forebrain lesions and cholinergic-rich grafts. Can J Psychol 44:210-232
9. Dunnett SB (1993) Operant delayed matching and non-matching to position in rats. In: Sahgal A (ed) Behavioural neuroscience, a practical approach, vol I. Oxford University Press, New York, pp 123-136
10. Dunnett SB, Evenden JL, Iversen SD (1988) Delay-dependent short-term memory deficits in aged rats. Psychopharmacology 96:174-180
11. Dunnett SB, Wareham AT, Torres EM (1990) Cholinergic blockade in prefrontal cortex and hippocampus disrupts short-memory in rats. Neuroreport 1:61-64
12. Hagan JJ, Morris GM (1989) The cholinergic hypothesis of memory: a review of animal experiments. In: Iversen LL, Iversen SD, Snyder SH (eds) Psychopharmacology of the aging nervous system. Handb Psychopharmacology 20:237-323
13. Herremans AHJ, Hijzen TH, Olivier B, Slangen JL (1995) Cholinergic drug effects on a delayed conditional discrimination task in the rat. Behav Neurosci 109:426-435
14. Jäkälä P, Sirviö J, Riekkinen P Jr, Riekkinen P (1993) Effects of p-chlorophenylalanine and methysergide on the performance of a working memory task. Pharmacol Biochem Behav 44: 411-418
15. Kirkby DL, Jones DNC, Higgins GA (1995) Influence of prefeeding and scopolamine upon performance in a delayed matching-to-position task. Behav Brain Res 67:221-227
16. Laurence DR, Stacey RS (1953) Mechanism of the prevention of nicotine convulsions by hexamethonium and by adrenaline blocking agents. Br J Pharmacol 8:62-65
17. MacDonald E, Sirviö J (1993) Neurotoxins as tools in lesioning experiments. In: Harvey AL (ed) Natural and synthetic neurotoxins. Academic Press, London, pp 1-46
18. McDonough JH, Shih T-M (1995) A study of the N-methyl-d-aspartate antagonistic properties of anticholinergic drugs. Pharmacol Biochem Behav 51:249-253
19. Moore H, Dudchenko P, Comer KS, Bruno JP, Sarter M (1992) Central versus peripheral effects of muscarinic antagonists: the limitations of quaternary ammonium derivatives. Psychopharmacology 108:241-243
20. Nilsson OG, Strecker RE, Daszuta A, Björklund A (1988) Combined cholinergic and serotonergic denervation of the forebrain produces severe deficits in a spatial learning task in the rat. Brain Res 453:235-246
21. O'Dell TJ, Christensen BN (1988) Mecamylamine is a selective noncompetitive antagonist of N-methyl-d-aspartate- and aspartate-induced currents in horizontal cells dissociated from catfish retina. Neurosci Lett 94:93-98
22. Olney JW, Farber NB (1995) NMDA antagonists as neurotherapeutic drugs, psychotogens, neurotoxins, and research tools for studying schizophrenia. Neuropsychopharmacology 13:335-345
23. Pitkänen M, Sirviö J, MacDonald E, Ekonsalo T, Riekkinen P Sr (1995) The effects of d-cycloserine, a partial agonist at the glycine binding site, on spatial learning and working memory in scopolamine-treated rats. J Neural Transm 9:133-144
24. Riekkinen P Jr, Sirviö J, Aaltonen M, Riekkinen P (1990) Effects of concurrent manipulations of nicotinic and muscarinic receptors on spatial and passive learning. Pharmacol Biochem Behav 37:405-410
25. Riekkinen P Jr, Sirviö J, Valjakka A, Miettinen R, Riekkinen P (1991) Pharmacological consequences of cholinergic plus serotonergic manipulations. Brain Res 552:23-26
26. Sahgal A, Keith AB (1993) Combined serotonergic-cholinergic lesions do not disrupt memory in rats. Pharmacol Biochem Behav 45:995-1001
27. Sahgal A, Keith AB, Lloyd S, Kerwin JM, Perry EK, Edwardson JA (1990) Memory following cholinergic (NBM) and noradrenergic (DNAB) lesions made singly or in combination: potentiation of disruption by scopolamine. Pharmacol Biochem Behav 37:597-605
28. Sakurai Y, Wenk GL (1990) The interaction of acetylcholinergic and serotonergic neural systems on performance in a continuous non-matching to sample task. Brain Res 159:118-121
29. Santucci AC, Moody E, Demetriades J (1995) Effects of scopolamine on spatial working memory in rats pretreated with the serotonergic depleter p-chloroamphetamine. Neurobiol Learn Mem 63:286-290
30. Steckler T, Sahgal A (1995) The role of serotonergic-cholinergic interactions in the mediation of cognitive behaviour. Behav Brain Res 67:165-199
31. Vanderwolf CH (1987) Near-total loss of "learning and memory" as a result of combined cholinergic and serotonergic blockade in the rat. Behav Brain Res 23:43-57
32. Wenk G, Hughey D, Boundy V, Kim A, Walker L, Olton D (1987) Neurotransmitters and memory: role of cholinergic, serotonergic, and noradrenergic systems. Behav Neurosci 101: 325-332