Effect of gonadotropin releasing hormone on thermoregulatory vasomotor activity in ovariectomized female rats

Brain Research

Volumn 754, Issue 1-2, 1997, Pages 88-94

  Hosono, Takayoshi ^a   Yanase Fujiwara, Motoko ^a   Zhang, Yi Hong ^a   Xiao ming, Chen ^a   Fukuda, Yutaka ^a   Asaki, Yasushi ^a   Yamaji, Kenji ^b   Kanosue, Kazuyuki ^b  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

female rat; gonadotropin releasing hormone; hot flush; preoptic area; septal area; thermoregulation; vasomotion

Indexed keywords

GONADORELIN; ITURELIX;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HOT FLUSH; INTRACEREBRAL DRUG ADMINISTRATION; NONHUMAN; OVARIECTOMY; PREOPTIC AREA; PRIORITY JOURNAL; RAT; SEPTUM NUCLEUS; THERMOREGULATION; VASOMOTOR REFLEX;

ANIMALS; BODY TEMPERATURE; BODY TEMPERATURE REGULATION; BRAIN; FEMALE; GONADOTROPIN-RELEASING HORMONE; HORMONE ANTAGONISTS; HYPOTHALAMUS; MICROINJECTIONS; OLIGOPEPTIDES; OVARIECTOMY; PREOPTIC AREA; RATS; RATS, WISTAR; SKIN; SKIN TEMPERATURE; VASODILATION;

EID: 0030932343     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00060-7     Document Type: Article

References (31)

1. Badr, M. and Pelletier, G., Characterization and autoradiographic localization of LHRH receptors in the rat brain, Synapse, 1 (1987) 567-571.
2. Casper, R.F., Yen, S.S.C. and Wilkes, M.M., Menopausal flushes: a neuroendocrine link with pulsatile luteinizing hormone secretion, Science, 205 (1979) 823-825.
3. Coope, J., Williams, S. and Patterson, J.S., A study of the effectiveness of propranolol in menopausal hot flushes, Br. J. Obstet. Gynaecol., 85 (1978) 472-475.
4. Dudley, C.A. and Moss, R.L., Facilitation of lordosis in female rats by CNS-site specific infusions of an LH-RH fragment, Ac-LH-RH-(5-10), Brain Res., 441 (1988) 161-167.
5. Gordon, C.J., Temperature Regulation in Laboratory Rodents, Cambridge University Press, Cambridge, 1993, pp. 73-81.
6. Hiruma, H., Funabashi, T. and Kimura, F., LHRH injected into the medial preoptic area potentiates LH secretion in ovariectomized estrogen-primed and proestrous rats, Neuroendocrinology, 50 (1989) 421-426.
7. Inagaki, K., Kihira, M., Suzuki, M. and Tomoda, Y., Effects of iontophoretically-applied LHRH, TRH, estrogen and clomiphene on thermosensitive neurons in the rat hypothalamus, Acta Obstet. Gynaecol. Jpn., 37, (1985), 611-618.
8. Jennes, L., Dalati, B. and Conn, P.M., Distribution of gonadotropin releasing hormone agonist binding sites in the rat central nervous system, Brain Res., 452 (1988) 156-164.
9. Kalra, S.P. and Kalra, P.S., Neural regulation of luteinizing hormone secretion in the rat, Endocr. Rev., 4 (1983) 311-351.
10. Kanosue, K., Niwa, K., Andrew, P.D., Yasuda, H., Yanase, M., Tanaka, H. and Matsumura, K., Lateral distribution of hypothalamic signals controlling thermoregulatory vasomotor activity and shivering in rats, Am. J. Physiol., 260 (1991) R486-R493.
11. Kanosue, K., Yanase-Fujiwara, M. and Hosono, T., Hypothalamic network for thermoregulatory vasomotor control, Am. J. Physiol., 267 (1994) R283-R288.
12. Katovich, M.J., Simpkins, J.W. and O'Meara, J., Effects of acute central LH-RH administration of the skin temperature response in morphine dependent rats, Brain Res., 494 (1989) 85-94.
13. Kronenberg, F., Hot flashes: epidemiology and physiology, Ann. NY Acad. Sci., 592 (1990) 52-86.
14. Lin, M.T., Chu, P.C. and Leu, S.Y., Effect of TSH, TRH, LH and LHRH on thermoregulation and food and water intake in the rat, Neuroendocrinology, 37 (1983) 206-211.
15. Lipton, J.M. and Glyn, J.R., Central administration of peptides alters thermoregulation in the rabbit, Peptides, 1 (1980) 15-18.
16. Ljungqvist, A., Feng, D.M., Tang, P.F.L., Kubota, M., Okamoto, T., Zhang, Y., Bowers, C.Y., Hook, W.A. and Folkers, K., Design, synthesis and bioassays of antagonists of LHRH which have high antiovulatory activity and release negligible histamine, Biochem. Biophys. Res. Commun., 148 (1987) 849-856.
17. Lomax, P., Bajorek, J.G., Chesarek, W. and Tataryn, I.V. Thermoregulatory effects of luteinizing hormone releasing hormone in the rat. In Thermoregulatory Mechanisms and their Therapeutic Implications. 4th Int. Symp. on the Pharmacology of Thermoregulation, Barsel, Karger, 1980, pp. 208-211.
18. Lumb, W.V. and Jones, E.W. Veterinary Anesthesia, Lea and Febiger, Philadelphia, 1984.
19. Merchenthaler, I., Gores, T., Sétáló, G., Petrusz, P. and Flerkó, B., Gonadotropin-releasing hormone (GnRH) neurons and pathways in the rat brain, Cell Tiss. Res., 237 (1984) 15-29.
20. Mulley, G., Mitchell, J.R.A. and Tattersall, R.B., Hot flushes after hypophysectomy, Br. Med. J., 2 (1977) 1062.
21. Osaka, T., Hori, T., Kiyohara, T., Shibata, M. and Nakashima, T., Changes in body temperature and thermosensitivity of preoptic and septal neurons during hippocampal stimulation, Brain Res. Bull., 13 (1984) 93-98.
22. Paxinos, G. and Watson, C. The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, San Diego, 1986.
23. Pfaff, D.W., Luteinizing hormone-releasing factor potentiates lordo-sis behavior in hypohysectomized ovariectomized female rats, Science, 182 (1973) 1148-1149.
24. Ravnikar, V., Elkind-Hirsch, K., Schiff, I., Ryan, K.J. and Tulchinsky, D., Vasomotor flushes and the release of peripheral immunoreactive luteinizing hormone-releasing hormone in postmenopausal women, Peril. Steril., 41 (1984) 881-887.
25. Richardson, D., Qing-Fu, H. and Shepherd, S., Effects of invariant sympathetic activity on cutaneous circulatory responses to heat stress, J. Appl. Physiol, 71 (1991) 521-529.
26. Risold, P.Y. and Swanson, L.W., Structural evidence for functional domains in the rat hippocampus, Science, 272 (1996) 1484-1486.
27. Schönbaum, E. The Climacteric Hot Flush, Karger, Basel, 1991.
28. South, S.A., Yankov, V.I. and Evans, W.S., Normal reproductive neuroendocrinology in the female, Endocrinol. Metab. Clin. North Am., 22 (1993) 1-28.
29. Swanson, L.W. and Cowan, L.W., The connections of the septal region in the rat, J. Comp. Neuraol., 186 (1979) 621-656.
30. Zhang, Y.-H., Yamada, K., Hosono, T., Chen, X.-M., Shiosaka, S. and Kanosue, K., Efferent neuronal organization for thermoregulatory vasomotor control, Ann. NY Acad. Sci., in press.
31. Zhang, Y.H., Yanase-Fujiwara, M., Hosono, T. and Kanosue, K., Warm-sensitive and cold-sensitive neurones in the rat's preoptic area: which contribute more to the control of shivering? J. Physiol., 485 (1995) 195-202.