Primary induction of human cytotoxic lymphocytes against a synthetic peptide of the human immunodeficiency virus type 1 protease

Journal of General Virology

Volumn 78, Issue 9, 1997, Pages 2217-2224

  Kónya, József ^a,b   Stuber, György ^a   Björndal, Åsa ^a   Fenyö, Eva Maria ^a   Dillner, Joakim ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAG PROTEIN; PROTEINASE; SYNTHETIC PEPTIDE; VIRUS ENZYME;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BLOOD DONOR; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VIRUS IMMUNITY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030931884     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-78-9-2217     Document Type: Article

References (38)

1. Baier, M., Werner, A., Bannert, N., Metzner, K. & Kurth, R. (1995). HIV suppression by interleukin-16. Nature 37, 563.
2. Cocchi, F., De Vico, A. L., Garzino-Demo, A., Arya, S. K., Gallo, R. C. & Lusso, P. (1995). Identification of RANTES, MIP-1α and MIP-1α as major HIV-suppressive factors produced by CD8+ T cells. Science 27, 1811-1815.
3. Couillin, I., Connan, F., Culmannpenciolelli, B., Gomard, E., Guillet, J. G. & Choppin, J. (1995). HLA-dependent variations in human immunodeficiency virus Nef protein alter peptide HLA binding. European Journal of Immunology 25, 728-732.
4. Croft, M. (1994). Activation of naive, memory and effector T cells. Current Opinion in Immunology 6, 413-437.
5. del Guercio, M. F., Sidney, J., Hermanson, G., Perez, C., Grey, H. M., Kubo, R. T. & Sette, A. (1995). Binding of a peptide antigen to multiple HLA alleles allows definition of an A2-like supertype. Journal of Immunology 154, 685-693.
6. Demaria, A., Cirillo, C. & Moretta, L. (1994). Occurrence of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic T cell activity in apparently uninfected children born to HIV-1-infected mothers. Journal of Infectious Diseases 170, 1296-1299.
7. Gotch, F., Rothbard, J., Howland, K., Townsend, A. & McMichael, A. (1987). Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2. Nature 326, 881-882.
8. Harrer, E., Harrer, T., Barbosa, P., Feinberg, M., Johnson R. P., Buchbinder, S. & Walker B. D. (1996a). Recognition of the highly conserved YMDD region in the human immunodeficiency virus type 1 reverse transcriptase by HLA-A2-restricted cytotoxic T lymphocytes from an asymptomatic long-term nonprogressor. Journal of Infectious Diseases 173, 476-479.
9. Harrer, T., Harrer, E., Kalams, S. A., Barbosa, P., Trocha, A., Johnson, R. P., Elbeik, T., Feinberg, M. B., Buchbinder, S. & Walker, B. D. (1996b). Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection. Journal of Immunology 156, 2616-2623.
10. Ho, M., Armstrong, J., McMahon, D., Pazin, G., Huang, X. L., Rinaldo, C., Whiteside, T., Tripoli, C., Levine, G., Moody, D. and others (1993). A phase 1 study of adoptive transfer of autologous CD8+ T lymphocytes in patients with acquired immunodeficiency syndrome (AIDS)-related complex or AIDS. Blood 81, 2093-2101.
11. Hsueh, F. W., Walker, C. M., Blackbourn, D. J. & Levy, J. A. (1994). Suppression of HIV replication by CD8+ cell clones derived from HIV-infected and uninfected individuals. Cellular Immunology 159, 271-279.
12. Irwin, M. J., Heath W. R. & Sherman L. A. (1989). Species restricted interactions between CD8 and a3 domain of class I influence the magnitude of xenogenic response. Journal of Experimental Medicine 170, 1091-1101.
13. Kageyama, S., Tsomides, T. J., Sykulev, Y. & Eisen, H. N. (1995). Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. Journal of Immunology 154, 567-576.
14. Kast, W. M., Brandt, R. M., Sidney, J., Drijfhout, J. W., Kubo, R. T., Grey, H. M., Melief, C. J. & Sette, A. (1994). Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins. Journal of Immunology 152, 3904-3912.
15. Klenerman, P., Rowland-Jones, S. L., McAdam, S., Edwards, J., Daenke, S., Lalloo, D., Koppe, B., Rosenberg, W., Boyd, D., Edwards, A. and others (1994). Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants. Nature 369, 403-407.
16. Koup, R. A., Safrit, J. T., Cao, Y. Z., Andrews, C. A., McLeod, G., Borkowsky, W., Farthing, C. & Ho, D. D. (1994). Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. Journal of Virology 68, 4650-4655.
17. Lamhamedicherradi, S., Culmannpenciolelli, B., Guy, B., Ly, T. D., Goujard, C., Guillet, J. G. & Gomard, E. (1995). Different patterns of HIV-1-specific cytotoxic T-lymphocyte activity after primary infection. AIDS 9, 421-426.
18. Langlade, D. P., Ngo-Giang-Huong, N., Ferchal, F. & Oksenhendler, E. (1994). Human immunodeficiency virus (HIV) Net-specific cytotoxic T lymphocytes in noninfected heterosexual contact of HIV-infected patients. Journal of Clinical Investigation 93, 1293-1297.
19. Levy, J. A. (1995). HIV research: a need to focus on the right target. Lancet 345, 1619-1621.
20. Levy, J. A. (1996). Controlling HIV pathogenesis: the role of the noncytotoxic anti-HIV response of CD8+ T cells. Immunology Today 17, 217-224.
21. Macatonia, S. E., Patterson, S. & Knight, S. C. (1991). Primary proliferative and cytotoxic T-cell responses to HIV induced in vitro by human dendritic cells. Immunology 74, 399-406.
22. Mackewicz, C. E., Blackbourn, D. J. & Levy, J. A. (1995). CD8+ T cells suppress human immunodeficiency virus replication by inhibiting viral transcription. Proceedings of the National Academy of Sciences, USA 92, 2308-2312.
23. Moss, P., Rowland-Jones, S. L., Frodsham, P. M., McAdam S., Giangrande, P., McMichael, A. J. & Bell J. I. (1995). Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors. Proceedings of the National Academy of Sciences, USA 92, 5773-5777.
24. Myers, G., Wain-Hobson, S., Henderson, L. E., Korber, B., Kuan-Teh, J. & Pavlakis, G. N. (1996). Compilation and analysis of nucleic acid and amino acid sequences. Human retroviruses and AIDS. Theoretical Biology and Biophysics, Los Alamos National Library, Los Alamos, New Mexico, USA (Internet location: http://hiv-web.lanl.gov/).
25. Nowak, M. A., May, R. M., Phillips, R. E., Rowland-Jones, S. L., Lalloo, D. G., McAdam, S., Klenerman, P., Koppe, B., Sigmund, K., Bangham, C. & McMichael, A. J. (1995). Antigenic oscillations and shifting immunodominance in HIV-1 infections. Nature 375, 606-611.
26. Phillips, R. E., Rowland-Jones, S. L., Nixon, D. F., Gotch, F. M., Edwards, J. P., Ogunlesi, A. O., Elvin, J. G., Rothbard, J. A., Bangham, C. R., Rizza, C. R. and others (1991). Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature 354, 453-459.
27. Pinto, L. A., Sullivan, J., Berzofsky, J. A., Clerici, M., Kessler, H. A., Landay, A. L. & Shearer, G. M. (1995). Env-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids. Journal of Clinical Investigation 96, 867-876.
28. Ressing, M. E., Sette, A., Brandt, R. M., Ruppert, J., Wentworth, P. A., Hartman, M., Oseroff, C., Grey, H. M., Melief, C. J. & Kast, W. M. (1995). Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides. Journal of Immunology 154, 5934-5943.
29. Rowland-Jones, S. L. & McMichael, A. (1995). Immune responses in HIV-exposed seronegatives - have they repelled the virus? Current Opinion in Immunology 7, 448-455.
30. Rowland-Jones, S. L., Sutton, J., Ariyoshi, K., Dong, T., Gotch, F., McAdam, S., Whitby, D., Sabally, S., Gallimore, A., Corrah, T., Takiguchi, M., Schultz, T., McMichael, A. & Whittle, H. (1995). HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women. Nature Medicine 1, 59-64.
31. Salter, R. D. & Cresswell, P. (1986). Impaired assembly and transport of HLA-A and -B antigens in a mutant T x B cell hybrid. EMBO Journal 5, 943-949.
32. Stuber, G., Dillner, J., Modrow, S., Wolf, H., Szekely, L., Klein, G. & Klein, E. (1995). HLA-A0201 and HLA-B7 binding peptides in the EBV-encoded EBNA-1, EBNA-2 and BZLF-1 proteins detected in the MHC class I stabilization assay. Low proportion of binding motifs for several HLA class I alleles in EBNA-1. International Immunology 7, 653-663.
33. Sundqvist, V. A., Albert, J., Ohlsson, E., Hinkula, J., Fenyö, E. M. & Wahren, B. (1989). Human immunodeficiency virus type 1 p24 production and antigenic variation in tissue culture of isolates with various growth characteristics. Journal of Medical Virology 29, 170-175.
34. Tsubota, H., Lord, C. I., Watkins, D. I., Morimoto, C. & Letvin, N. L. (1989). A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytes. Journal of Experimental Medicine 169, 1421-1434.
35. Vanderburg, S. H., Klein, M. R., Vandevelde, C., Kast, W. M., Miedema, F. & Melief, C. (1995). Induction of a primary human cytotoxic T-lymphocyte response against a novel conserved epitope in a functional sequence of HIV-1 reverse transcriptase. AIDS 9, 121-127.
36. Vitiello, A., Ishioka, G., Grey, H. M., Rose, R., Farness, P., LaFond, R., Yuan, L., Chisari, F. V., Furze, J., Bartholomeuz, R. and others (1995). Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans. Journal of Clinical Investigation 95, 341-349.
37. Walker, B. D., Chakrabarti, S., Moss, B., Paradis, T. J., Flynn, T., Durno, A. G., Blumberg, R. S., Kaplan, J. C., Hirsch, M. S. & Schooley, R. T. (1987). HIV-spedfic cytotoxic T lymphocytes in seropositive individuals. Nature 328, 345-348.
38. Walker, B. D., Flexner, C., Paradis, T. J., Fuller, T. C., Hirsch, M. S., Schooley, R. T. & Moss, B. (1988). HIV-1 reverse transcriptase is a target for cytotoxic T lymphocytes in infected individuals. Science 240, 64-66.