Werner's syndrome - Chromosome analyses of cultured fibroblasts and mitogen-stimulated lymphocytes

British Journal of Dermatology

Volumn 136, Issue 4, 1997, Pages 620-623

  Morita, K ^a   Nishigori, C ^a   Sasaki, M S ^a   Matsuyoshi, N ^a   Ohta, K ^a   Okamoto, H ^a   Ikai, K ^a   Imamura, S ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CASE REPORT; CELL CULTURE; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; FEMALE; FIBROBLAST; HUMAN; LYMPHOCYTE; PRIORITY JOURNAL; SKIN ULCER; WERNER SYNDROME;

EID: 0030931286     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.1997.tb02156.x     Document Type: Article

References (9)

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5. Scappaticci S, Cerimele D, Fraccaro M. Clonal structural chromosomal rearrangements in primary fibroblast cultures and in lymphocytes of patients with Werner's syndrome. Hum Genet 1982; 62: 16-24.
6. Thannhauser SJ. Werner's syndrome (progeria of the adult) and Rothmund's syndrome: two types of closely related heredofamilial atrophic dermatosis with juvenile cataracts and endocrine features. A critical study with five new cases. Ann Intern Med 1945; 23: 559.
7. Martin GM, Sprague CA, Epstein CJ. Replicative life-span of cultivated human cells. Lab Invest 1970; 23: 86-92.
8. Goldstein S, Murano S, Shmookler-Reis RJ. Werner syndrome: a molecular genetic hypothesis. J Gerontol 1990; 45: B3-8.
9. Cheng RZ, Murano S, Kurz B et al. Homologous recombination is elevated in some Werner-like syndromes but not during normal in vitro or in vivo senescence of mammalian cells. Mutat Res 1990; 257: 259-69.