Functional characterization of monoclonal antibody inhibitors of α2- antiplasmin that accelerate fibrinolysis in different animal plasmas

Hybridoma

Volumn 16, Issue 3, 1997, Pages 281-286

  Reed, Guy L ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ANTIPLASMIN; MONOCLONAL ANTIBODY; PLASMINOGEN ACTIVATOR; UROKINASE;

ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; BABOON; BLOOD CLOT LYSIS; CROSS REACTION; DOG; FERRET; FIBRINOLYSIS; HUMAN; IMMUNOBLOTTING; MONKEY; NONHUMAN; PLASMA; PRIORITY JOURNAL;

ANIMALIA; CANIS FAMILIARIS; CERCOPITHECUS AETHIOPS; MUSTELA PUTORIUS FURO; PAPIO HAMADRYAS; PRIMATES; THROMBUS;

EID: 0030930512     PISSN: 0272457X     EISSN: None     Source Type: Journal    
DOI: 10.1089/hyb.1997.16.281     Document Type: Article

References (22)

1. Verstraete M, and Collen D: Thrombolytic therapy in the eighties. Blood 1986;67:1529-41.
2. Marder VJ, and Sherry S: Thrombolytic therapy: Current status. New Engl J Med 1988;318:1512-20;1585-95.
3. Karagounis L, Sorensen SG, Menlove RL, Moreno F, and Anderson JL: Does thrombolysis in myocardial infarction (TIM1) perfusion grade 2 represent a mostly patent artery or a mostly occluded artery? Enzymatic and electrocardiographic evidence from the TEAM-2 study. Second Multicenter Thrombolysis Trial of Eminase in Acute Myocardial Infarction. J Amer Coll Cardiol 1992;19:1-10.
4. Simes RJ, Topol EJ, Holmes DR Jr., White HD, Rutsch WR, Vahanian A, Simoons ML, Morris D, Betriu A, Califf RM, and Ross AM, for the GUSTO-I investigators: Link between the angiographie substudy and mortality outcomes in a large randomized trial of myocardial reperfusion. Importance of early and complete infarct artery reperfusion. Circulation 1995 Apr 1;91:1905-1907.
5. Lincoff AM, Topol EJ, Califf RM, Sigmon KN, Lee KL, Ohman EM, Rosenschein U, and Ellis SG: Significance of a coronary artery with thrombolysis in myocardial infarction grade 2 flow "patency" (outcome in the thrombolysis and angioplasty in myocardial infarction trials). Thrombolysis and Angioplasty in Myocardial Infarction Study Group. Am J Cardiol 1995;75:871-876.
6. Goldhaber SZ, Vaughn DE, Markis JE et al: Acute pulmonary embolism treated with tissue plasminogen activator. Lancet 1986;2:886-889.
7. Goldhaber SZ, Meyerovitz MF, Green D, Vogelzang RL, Citrin P, Heit J et al: Randomized controlled trial of tissue plasminogen activator in proximal deep venous thrombosis. Am J Med 1990;88:235-240.
8. Salzman EW, and Hirsch J: The epidemiology, pathogenesis and natural history of venous thrombosis. In: Colman RW, Hirsh J, Marder VJ, Salzman EW, eds., Hemostasis and thrombosis: Basic principles and clinical practice, 3rd ed. Lippincott, Philadelphia, PA 1994.
9. Collen D: Identification and some properties of a new fast reacting plasmin inhibitor in human plasma. Eur J Biochem 1976;69:209-216.
10. Moroi M, and Aoki N: Isolation and characterization of a2-plasmin inhibitor from human plasma. J Biol Chem 1976;251:5956-5965.
11. Mullertz S, and Clemmensen I: The primary inhibitor of plasmin in human plasma. Biochem J 1976;159:545-553.
12. 2-plasmin inhibitor to fibrin in inhibition of fibrinolysis and hemostasis. J Clin Invest 1982;69:536-542.
13. 2-plasmin inhibitor deficiency. Blood 1983;62:1118-1122.
14. 2-antiplasmin. Proc Natl Acad Sci USA 1990;87:1114-1118.
15. Galfre G, Howe SC, Milstein C, Butcher GW, and Howard JC: Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature 1977;266:680-685.
16. Lukacova D, Matsueda GR, Haber E, and Reed GL: Inhibition of factor XIII activation by an anti-peptide monoclonal antibody. Biochemistry 1991;30:10164-10170.
17. Kyhse-Anderson, J: Electroblotting of multiple gels: A simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. J Biochem Biophys Meth 1984;10:203-209.
18. Fraker PJ, and Speck JJ: Protein and cell membrane iodinations with sparingly soluble cholarmide l,3,4,6-tetracholo-3a,6a-diphenylglycouricil. Biochem Biophys Res Commun 1978;80:849-857.
19. Mudgett-Hunter M, Anderson W, Haber E, and Margolies MN: Binding and structural diversity among high-affinity monoclonal anti-digoxin antibodies. Mol Immunol 1985;22:477-488.
20. 2-antiplasmin and plasmin. Eur J Biochem 1978;84:573-578.
21. 2-antiplasmin and plasmin. J Biol Chem 1979;254:9291-9297.
22. 2-antiplasmin and plasmin stopped-flow fluorescence kinetics. FEBS Lett 1996;387:58-62.