Does p53 overexpression cause metastases in early invasive colorectal adenocarcinoma?

European Journal of Surgery

Volumn 163, Issue 9, 1997, Pages 685-692

  Sory, Andrzej ^a,b   Minamoto, Toshinari ^a   Ohta, Takahito ^a   Yamashita, Kaname ^a   Sawaguchi, Kiyoshi ^a   Mai, Masayoshi ^a   Misiuna, Pawel ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Early colorectal cancer; Metastases; p53 overexpression

Indexed keywords

PROTEIN P53;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; CANCER INVASION; CLINICAL ARTICLE; CLINICAL FEATURE; COLORECTAL CARCINOMA; EARLY CANCER; ENDOSCOPIC SURGERY; FEMALE; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; JAPAN; LYMPH NODE METASTASIS; MALE; METASTASIS POTENTIAL; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTATION; NEOPLASM INVASIVENESS; PROGNOSIS; RETROSPECTIVE STUDIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0030930207     PISSN: 11024151     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Aaltonen LA, Peltomäki P, Leach FS, et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993; 260: 812-816.
2. Bell SM, Scott N, Cross D, et al. Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer. Gastroenterology 1993; 104: 57-64.
3. Brodsky JT, Richard GK, Cohen AM, Minsky BD. Variables correlated with the risk of lymph node metastasis in early rectal cancer. Cancer 1992; 69: 322-326.
4. Cohen AM, Tremiterra S, Candela F, Thaler HT, Sigurdson ER. Prognosis of node-positive colon cancer. Cancer 1991; 67: 1859-1861.
5. Colacchio TA, Forde KA, Scantlebury VP. Endoscopic polypectomy. Inadequate treatment for invasive colorectal carcinoma. Ann Surg 1981; 194: 704-707.
6. Coverlizza S, Risio M, Ferrari A, Fenoglio-Preiser CM, Rossini FP. Colorectal adenomas containing invasive carcinoma. Pathologic assessment of lymph node metastatic potential. Cancer 1989; 64: 1937-1947.
7. Crawford BE, Stromeyer FW. Small nonpolypoid carcinomas of the large intestine. Cancer 1983; 51: 1760-1763.
8. Delattre O, Olschwang S, Law DJ, et al. Multiple genetic alterations in distal and proximal colorectal cancer. Lancet 1989; ii: 353-355.
9. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-767.
10. Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ. Activating mutations for transformation by p53 produce a gene product that forms on hsp 70-p53 complex with an altered half-life. Mol Cell Biol 1988; 8: 531-539.
11. Haggitt RC, Glotzbach RE, Soffer EE, Wruble LD. Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy. Gastroenterology 1985; 89: 328-336.
12. Haggitt RC. Controversies and dialogues. When is colonoscopic resection of an adenomatous polyp containing a "malignancy" sufficient? Am J Gastroenterol 1990; 85: 1566-1568.
13. Hamelin R, Laurent-Puig P, Olschwang S, et al. Association of p53 mutations with short survival in colorectal cancer. Gastroenterology 1994; 106: 42-48.
14. Hermanek P, Gall FP. Early (microinvasive) colorectal carcinoma. Pathology, diagnosis, surgical treatment. Int J Colorect Dis 1986; 1: 79-84.
15. Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993; 363: 558-561.
16. Japanese Research Society for Cancer of the Colon and Rectum. General rules for clinical and pathological studies on cancer of the colon, rectum and anus. Part I. Clinical classification. Jpn J Surg 1983; 13: 557-573.
17. Japanese Research Society for Cancer of the Colon and Rectum. General rules for clinical and pathological studies on cancer of the colon, rectum and anus. Part II. Histopathological classification. Jpn J Surg 1983; 13: 574-598.
18. Jelinek GP, Nava HR, Nime F. Small primary de novo adenocarcinoma of the colon with mesenteric lymphatic metastasis. J Surg Oncol 1983; 23: 185-188.
19. Kikuchi-Yanoshita R, Konishi M, Ito S, et al. Genetic changes of both p53 alleles associated with the conversion from colorectal adenoma to early carcinoma in familial adenomatous polyposis and non-familial adenomatous polyposis patients. Cancer Res 1992; 52: 3965-3971.
20. Minamoto T, Mai M, Ogino T, et al. Early invasive colorectal carcinomas metastatic to the lymph node with attention to their nonpolypoid development. Am J Gastroenterol 1993; 88: 1035-1039.
21. Minamoto T, Sawaguchi K, Ohta T, Itoh T, Mai M. Superficial-type adenomas and adenocarcinomas of the colon and rectum: a comparative morphological study. Gastroenterology 1994; 106: 1436-1443.
22. Nathanson SD, Linden MD, Tender P, Zarbo RJ, Jacobsen G, Nelson LT. Relationship among p53, stage, and prognosis of large bowel cancer. Dis Colon Rectum 1994; 37: 527-534.
23. Nivatvongs S, Rojanasakul A, Reiman HM, et al. The risk of lymph node metastasis in colorectal polyps with invasive adenocarcinoma. Dis Colon Rectum 1991; 34: 323-328.
24. Pignatelli M, Stamp GWH, Kafiri G, Lane D, Bodmer WF. Over-expression of p53 nuclear oncoprotein in colorectal adenomas. Int J Cancer 1992; 50: 683-688.
25. Purdie CA, O'Grady J, Pins J, Wyllie AH, Bird CC. Rapid communication. p53 expression in colorectal tumors. Am J Pathology 1991; 138: 807-813.
26. Remvikos Y, Tominaga O, Hammel P, et al. Increased p53 protein content of colorectal tumors correlates with poor survival. Br J Cancer 1992; 66: 758-764.
27. Rothberg PG, Spandorfer JM, Erisman MD, et al. Evidence that c-myc expression defines two genetically distinct forms of colorectal adenocarcinoma. Br J Cancer 1985; 52: 629-632.
28. Sawada T, Hojo K, Moriya Y. Colonoscopic management of focal and early colorectal carcinoma. Bailliere's Clin Gastroenterol 1989; 3: 627-645.
29. Scott NP, Sagar P, Stewart J, Blair GE, Dixon MF, Quirke P. p53 in colorectal cancer: clinicopathological correlations and prognosis significance. Br J Cancer 1991; 63: 317-319.
30. Shimoda T, Ikegami M, Fujisaki J, Matsui T, Aizawa S, Ishikawa E. Early colorectal carcinoma with special reference to its development de novo. Cancer 1989; 64: 1138-1146.
31. Spratt JS, Ackerman LV. Small primary adenocarcinomas of the colon and rectum. JAMA 1962; 179: 337-346.
32. Starzynska T, Bromley M, Ghosh A, Stern PL. Prognostic significance of p53 overexpression in gastric and colorectal cancer. Br J Cancer 1992; 66: 558-562.
33. Sugihara K, Muto T, Morioka Y. Management of patients with invasive carcinoma removed by colonoscopic polypectomy. Dis Colon Rectum 1989; 32: 829-834.
34. Sun XF, Carstensen JM, Zhang H, et al. Prognostic significance of cytoplasmic p53 oncoprotein in colorectal adenocarcinoma. Lancet 1992; 340: 1369-1373.
35. Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993; 260: 816-819.
36. Tomoda H, Kakeji Y. Immunohistochemical analysis of p53 in colorectal cancer regarding clinicopathological correlation and prognostic significance. J Surg Oncol 1995; 58: 125-128.
37. Van Den Berg FM, Tigges AJ, Schipper MEI, den Hartog-Jager FCA, Kroes WGM, Walboomers JMM. Expression of the nuclear oncogene p53 in colon tumours. J Pathol 1989; 157: 193-199.
38. Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal tumor development. N Engl J Med 1988; 319: 525-532.
39. Wilcox GM, Anderson PB, Colacchio TA. Early invasive carcinoma in colonic polyps. A review of the literature with emphasis on the assessment of the risk of metastasis. Cancer 1986; 57: 160-171.
40. Wynford-Thomas D. p53 in tumour pathology: can we trust immunocytochemistry? J Pathol 1992; 166: 329-330.
41. Yamaguchi A, Makimoto K, Goi T, et al. Over-expression of p53 protein and proliferative activity in colorectal adenoma. Oncology 1994; 51: 224-227.
42. Yamaguchi A, Kurosaka Y, Fushida S, et al. Expression of p53 protein in colorectal cancer and its relationship to short-term prognosis. Cancer 1992; 70: 2778-2784.