The TSG101 tumor susceptibility gene is located in chromosome 11 band p15 and is mutated in human breast cancer

Cell

Volumn 88, Issue 1, 1997, Pages 143-154

  Li, Limin ^a   Li, Xu ^a   Francke, Uta ^a   Cohen, Stanley N ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER SUSCEPTIBILITY; CHROMOSOME 11P; CLINICAL ARTICLE; CONTROLLED STUDY; GENE DELETION; GENE MUTATION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL;

EID: 0030929782     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81866-8     Document Type: Article

References (57)

1. Ali, I.U., Lidereau, R., Theillet, C., and Callahan, R. (1987). Reduction to homozygosity of genes on chromosome 11 in human breast neoplasia. Science 238, 185-188.
2. Baffa, R., Negrini, M., Mandes, B., Rugge, M., Ranzani, G.N., Hirohashi, S., and Croce, C.M. (1996). Loss of heterozygosity for chromosome 11 in adenocarcinoma of the stomach. Cancer Res. 56, 268-272.
3. Barnes, W.M. (1994). PCR amplification of up to 35-kb DNA with high fidelity and high yield from I bacteriophage templates. Proc. Natl. Acad. Sci. USA 91, 2216-2220.
4. Bieche, I., and Lidereau, R. (1995). Genetic alterations in breast cancer. Genes Chromosomes Cancer 14, 227-251.
5. Booth, P.M., Buchman, G.W., and Rashtchian, A. (1994). Assembly and cloning of coding sequences for neurotropic factors directly from genomic DNA using polymerase chain reaction and uracil DNA glycosylation. Gene 146, 303-308.
6. Brattsand, G., Roos, G., Marklund, U., Ueda, H., Landberg, G., Nanberg, E., Sideras, P., and Gullberg, M. (1993). Quantitative analysis of the expression and regulation of an activation-regulated phosphoprotein (oncoprotein 18) in normal and neoplastic cells. Leukemia 7, 569-579.
7. Brewster, S.F., Gingell, J.C., Browne, S., and Brown, K.W. (1994). Loss of heterozygosity on chromosome 18q is associated with muscle-invasive transitional cell carcinoma of the bladder. Br. J. Cancer 70, 697-700.
8. Byrne, J.A., Simms, L.A., Little, M.H., Algar, E.M., and Smith, P.J. (1993). Three non-overlapping regions of chromosome arm 11p allele loss identified in infantile tumors of adrenal and liver. Genes Chromosomes Cancer 8, 104-111.
9. Chen, L.C., Kurisu, W., Ljung, B.M., Goldman, E.S., Moore, D., and Smith, H.S. (1992). Heterogeneity for allelic loss in human breast cancer. J. Natl. Cancer Inst. 84, 506-510.
10. Cowell, J.K., Groves, N., and Baird, P. (1993). Loss of heterozygosity at 11p13 in Wilms' tumours does not necessarily involve mutations in the WT1 gene. Br. J. Cancer 67, 1259-1261.
11. Derry, J.M., Jess, U., and Francke, U. (1995). Cloning and Characterization of a Novel Zinc Finger Gene in Xp11.2. Genomics 30, 361-365.
12. Dowdy, S.F., Fasching, C.L., Araujo, D., Lai, K.M., Livanos, E., Weissman, B.E., and Stanbridge, E.J. (1991 (.Suppression of tumorigenicity in Wilms tumor by the p15.5-p14 region of chromosome 11. Science 254, 293-295.
13. Ferti-Passantonopoulou, P.A., Panani, A.D., and Raptis, S. (1991). Preferential involvement of 11q23-24 and 11p15 in breast cancer. Cancer Genet. Cytogenet. 51, 183-188.
14. Fong, K.M., Zimmerman, P.V., and Smith, P.J. (1994). Correlation of loss of heterozygosity at 11 p with tumour progression and survival in non-small cell lung cancer. Genes Chromosomes Cancer 10, 183-189.
15. Francke, U., Yang, FT., Brissenden, J.E., and Ullrich, A. (1986). Chromosomal mapping of genes involved in growth control. Cold Spring Harbor Symp. Quant. Biol. 51, 855-866.
16. Francke, U. (1994). Digitized and differentially shaded human chromosome ideograms for genomic applications. Cytogenet. Cell Genet. 65, 206-219.
17. Fults, D., Petronio, J., Noblett, B.D., and Pedone, C.A. (1992). Chromosome 11p15 deletions in human malignant astrocytomas and primitive neuroectodermal tumors. Genomics 14, 799-801.
18. Futreal, P.A., Liu, Q., Shattuck-Eidens, D., Cochran, C., Harshman, K., Tavtigian, S., and Bennett, L.M. (1994). BRCA1 mutations in primary breast and ovarian carcinomas. Science 266, 120-122.
19. Gudmundsson, J., Barkardottir, R.B., Eiriksdottir, G., Baldursson, T., Arason, A., Egilsson, V., and Ingvarsson, S. (1995). Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations. Br. J. Cancer 72, 696-701.
20. Hanash, S.M., Strahler, J.R., Kuick, R., Chu, E.H., and Nichols, D. (1988). Identification of a polypeptide associated with the malignant phenotype in acute leukemia. J. Biol. Chem. 263, 12813-12815.
21. Harris, J.R., Morrow, M., and Bonadonna, G. (1993). Cancer of the breast. In Cancer, Principles and Practice of Oncology, V.T. DeVita, Jr., S. Hellman, and S.A. Rosenberg, eds. (Philadephia, Pennsylvania: J.B. Lippincott), p. 1277.
22. Karnik, P., Plummer, S., Casey, G., Myles, J., Tubbs, R., Crowe, J., and Williams, B.R. (1995). Microsatellite instability at a single locus (D11S988) on chromosome 11p15.5 as a late event in mammary tumorigenesis. Hum. Mol. Genet. 4, 1889-1894.
23. Koi, M., Johnson, LA., Kalikin, L.M., Little, P.F., Nakamura, Y., and Feinberg, A.P. (1993). Tumor cell growth arrest caused by subchromosomal transferable DNA fragments from chromosome 11. Science 260, 361-364.
24. Kondo, M., Suzuki, H., Ueda, R., Takagi, K., Takahashi, T., and Takahashi, T. (1994). Parental origin of 11p15 deletions in human lung cancer. Oncogene 9, 3063-3065.
25. Lancaster, J.M., Wooster, R., Mangion, J., Phelan, C.M., Cochran, C., Gumbs, C., Seal, S., Barfoot, R., Collins, N., Bignell, G., et al. (1996). BRCA2 mutations in primary breast and ovarian cancers. Nature Gen. 13, 238-240.
26. Li, L., and Cohen, S.N. (1996). tsg101: a novel tumor susceptibility gene isolated by controled homozygous functional knockout of allelic loci in mammalian cells. Cell 85, 319-329.
27. Li, X., Pereira, L., Zhang, H., Sanguineti, C., Ramirez, F., Bonadio, J., and Francke, U. (1993). Fibrillin genes map to regions of conserved mouse/human syntenyon mouse chromosomes 2 and 18. Genomics 18, 667-672.
28. Li, X., Ho, S.N., Luna, J., Giacalone, J., Thomas, D.J., Timmerman, L.A., Crabtree, G.R., and Francke, U. (1995a). Cloning and chromosomal localization of the human and murine genes for the T-cell transcription factors NFATc and NFATp. Cytogenet. Cell Genet. 71, 185-191.
29. Li, X., Rosahl, T.W., Sudhof, T.C., and Francke, U. (1995b). Mapping of synapsin II (SYN2) genes to human chromosome 3p and mouse chromosome 6 band F. Cytogenet. Cell Genet.71, 301-305.
30. Lichy, J.H., Modi, W.S., Seuanez, H.N., and Howley, P.M. (1992). Identification of a human chromosome 11 gene which is differentially regulated in tumorigenic and nontumorigenic somatic cell hybrids of HeLa cells. Cell Growth Diff. 3, 541-548.
31. Lothe, R.A., Hastie, N., Heimdal, K., Fossa, S.D., Stenwig, A.E., and Borresen, A.L. (1993). Frequent loss of 11p13 and 11p15 loci in male germ cell tumours. Genes Chromosomes Cancer 7, 96-101.
32. Ludwig, C.U., Raefle, G., Dalquen, P., Stulz, P., Stahel, R., and Obrecht, J.P. (1991). Allelic loss on the short arm of chromosome 11 in non-small-cell lung cancer. Int. J. Cancer 49, 661-665.
33. Mackay, J., Elder, P.A., Porteous, D.J., Steel, C.M., Hawkins, R.A., Going, J.J., and Chetty, U. (1988). Partial deletion of chromosome 11p in breast cancer correlates with size of primary tumor and estrogen receptor level. Br. J. Cancer 58, 710-714.
34. Maucuer, A., Camonis, J.H., and Sobel, A. (1995). Stathmin interaction with a putative kinase and coiled-coil-forming protein domains. Proc. Natl. Acad. Sci. USA 92, 3100-3104.
35. Marklund, U., Brattsand, G., Osterman, O., Ohlsson, P.I., and Gullberg, M. (1993). Multiple signal transduction pathways induce phosphorylation of serines 16, 25, and 38 of oncoprotein 18 in T lymphocytes. J. Biol. Chem. 268, 25671-25680.
36. Miki, Y., Swensen, J., Shattuck, E.D., Futreal, P.A., Harshman, K., Tavtigian, S., Liu, Q., Cochran, C., Bennett, L.M., Ding, W., et al. (1994). A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266, 66-71.
37. Miki, Y., Katagiri, T., Kasumi, F., Yoshimoto, T., and Nakamura, Y. (1996). Mutation analysis in the BRCA2 gene in primary breast cancers. Nature Gen.13, 245-247.
38. Mitchell, P.J., and Tjian, R. (1989).Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245, 371-378.
39. Miyagi, M., Inazawa, J., Takita, K., and Nakamura, Y. (1992). Cloning and characterization of an interstitial deletion at chromosome 11p15 in a sporadic breast cancer. Hum. Mol. Genet.1, 705-708.
40. Nakamura, T., Largaespada, D.A., Lee, M.P., Johnson, L.A., Ohyashiki, K., Toyama, K., Chen, S.J., Willman, C.L., Chen, I.M., Feinberg, A.P., Jenkins, N.A., Copeland, N.G., and Shaughnessy, J.J. (1996). Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11) (p15;p15) in human myeloid leukaemia. Nat. Genet. 72, 154-158.
41. Negrini, M., Rasio, D., Hampton, G.M., Sabbioni, S., Rattan, S., Carter, S.L., Rosenberg, A.L., Schwartz, G.F., Shiloh, Y., Cavenee, W.K., and Grace, C.M. (1995). Definition and refinement of chromosome 11 regions of loss of heterozygosity in breast cancer: identification of a new region at 11q23.3. Cancer Res. 55, 3003-3007.
42. Phillips, K.K., Welch, D.R., Miele, M.E., Lee, J.H., Wei, L.L, and Weissman, B.E. (1996). Suppression of MDA-MB-435 breast carcinoma cell metastasis following the introduction of human chromosome 11. Cancer Res. 56, 1222-1227.
43. Presti, J.J., Reuter, V.E., Galan, T., Fair, W.R., and Cordon, C.C. (1991). Molecular genetic alterations in superficial and locally advanced human bladder cancer. Cancer Res. 51, 5405-5409.
44. Riley, J., Butler, R., Ogilvie, D., Finniear, R., Jenner, D., Powell, S., Anand, R., Smith, J.C., and Markham, A.F. (1990). A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones. Nucl. Acids Res. 18, 2887-2890.
45. Roos, G., Brattsand, G., Landberg, G., Marklund, U., and Gullberg, M. (1993). Expression of oncoprotein 18 in human leukemias and lymphomas. Leukemia 7, 1538-1546.
46. Seizinger, B.R., Klinger, H.P., Junien, C., Nakamura, Y., Le Beau, M., Cavenee, W., Emmanuel, B., Ponder, B., Naylor, S., Mitelman, F., et al. (1991). Eleventh workshop on human gene mapping. Report of the committee on chromosome and gene loss in human neoplasia. Cytogenet. Cell Genet. 58, 10080-10096.
47. Sellar, G.C., Jordan, S.A., Bickmore, W.A., Fantes, J.A., Van Heyningen, V., and Whitehead, A.S. (1994). The human serum Amyloid A protein (SAA) superfamily gene cluster: mapping to chromosome 11p15.1 by physical and genetic linkage analysis. Genomics 19, 221-227.
48. Smith, R.C., and Rukstalis, D.B. (1995). Frequent loss of heterozygosity at 11 p loci in testicular cancer. J. Ural. 153, 1684-1687.
49. Sobel, A. (1991). Stathmin: a relay phosphoprotein for multiple signal transduction? Trends Biochem. Sci. 16, 301-305.
50. Sozzi, G., Veronese, M.L., Negrini, M., Baffa, R., Cotticelli, M.G., Inoue, H., Tornielli, S., Pilotti, S., De Gregorio, L., Pastorino, U., et al. (1996). The FHilT Gene at 3p14.2 is Abnormal in Lung Cancer. Cell 85, 17-26.
51. Takita, K.-I., Tanigami, A., Tokino, T., Jones, C., and Nakamura, Y. (1992). Identification of 57 conventional RFLP and 6 VNTR systems with 32 DNA clones on chromosome 11p15. Genomics 13, 1296-1299.
52. Teng, D.H.-F., Bogden, R., Mitchell, J., Baumgard, M., Bell, R., Berry, S., Davis, T., Ha, P.C., Kehrer, R., Jammulapati, S., et al. (1996). Low incidence of BRCA2 mutations in breast carcinoma and other cancers. Nature Gen. 13 241-244.
53. Weitzel, J.N., Patel, J., Smith, D.M., Goodman, A., Safaii, H., and Ball, H.G. (1994). Molecular genetic changes associated with ovarian cancer. Gynecol. Oncol. 55, 245-252.
54. Winqvist, R., Mannermaa, A., Alavaikko, M., Blanco, G., Taskinen, P.J., Kiviniemi, H., Newsham, I., and Cavenee, W. (1993). Refinement of regional loss of heterozygosity for chromosome 11p15.5 in human breast tumors. Cancer Res. 53, 4486-4488.
55. Winqvist, R., Hampton, G.M., Mannermaa, A., Blanco, G., Alavaikko, M., Kiviniemi, H., Taskinen, P.J., Evans, G.A., Wright, F.A., Newsham, I., and Cavenee, W.K. (1995). Loss of heterozygosity for chromosome 11 in primary human breast tumors is associated with poor survival after metastasis. Cancer Res. 55, 2660-2664.
56. Wooster, R., Bignell, G., Lancaster, J., Swift, S., Seal, S., Mangion, J., Collins, N., Gregory, S., Gumbs, C., Micklem, G., et al. (1995). Identification of the breast cancer susceptibility gene BRCA2. Nature 378, 789-792.
57. Zhang, R.D., Fidler, I.J., and Price, J.E. (1991). Relative malignant potential of human breast carcinoma cell lines established from pleural effusions and a brain metastasis. Invasion Metastasis 11, 204-215.