The use of low-dose aprotinin, ε-aminocaproic acid or tranexamic acid for prevention of mediastinal bleeding in patients receiving aspirin before coronary artery bypass operations [2]

European Journal of Cardio-thoracic Surgery

Volumn 11, Issue 4, 1997, Pages 798-800

  Landymore, Roderick W ^a,b   Murphy, J Thomas ^a,b   Lummis, Heather ^a,b   Carter, Cheryl ^a,b  

^a KING FAHAD NATIONAL GUARD HOSPITAL   (Saudi Arabia)

^b QUEEN ELIZABETH II HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMINOCAPROIC ACID; APROTININ; TRANEXAMIC ACID;

BLEEDING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LETTER; MAJOR CLINICAL STUDY; MEDIASTINUM; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

EID: 0030929609     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1010-7940(96)01126-8     Document Type: Letter

References (9)

1. Fremes S, Wong B, Lee E, Mai R, Christakis G, McLean R, Goldman B, Naylor D. Metaanalysis of prophylactic drug treatment in the prevention of postoperative bleeding. Ann Thorac Surg 1994; 58: 1580-1588.
2. Blauhut B, Harringer W, Bettelheim P, Doran J, Spath P, Lungsgaard-Hansen P. Comparison of the effects of aprotinin and tranexamic acid on blood loss and related variables after cardiopulmonary bypass. J Thorac Cardiovasc Surg 1994; 108: 1083-1091.
3. Isetta C, Samat C, Kotaiche M, Jourdan J, Grimaud D. Low-dose aprotinin or tranexamic acid treatment in cardiac surgery. Anesthesiology 1991; 75: 80A.
4. Murkin J, McKenzie F, White S, Shannon N, Adams S. A comparison of complications of different antifibrinolytics in cardiac surgical patients undergoing repeat sternotomy. Anesth Analg 1995; 80: 132A.
5. Ralley F, DeVarennes B, Robitaille M. Comparison of aprotinin vs. placebo on blood loss for elective CABG surgery: are they necessary? Anesth Analg 1995; 80: 137A.
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7. Michelson E, Morganroth J, Torosian M, Macvaugh H. Relation of perioperative use of aspirin to increased mediastinal blood loss after coronary artery bypass surgery. J Thorac Cardiovasc Surg 1978; 76: 694-697.
8. Sethi G, Copeland J, Goldman S, Moritz T, Zadina K, Henderson W. Implications of preoperative administration of aspirin in patients undergoing coronary artery bypass grafting. J Am Coll Cardiol 1990; 15: 15-20.
9. Taggart D, Siddiqui L, Wheatley D. Low-dose preoperative aspirin therapy, postoperative blood loss and transfusion requirements. Ann Thorac Surg 1990; 50: 425-428.