Volumetric self-sampling of cervicovaginal fluid to determine potential fertility: A multicentre pre-effectiveness study of the Rovumeter®

Human Reproduction

Volumn 12, Issue 8, 1997, Pages 1826-1831

  Flynn, A M ^a   Collins, W P ^b,f   Royston, P ^c   Barbato, M ^d   Mena Gonzalez, P ^e   Alliende, M E ^e  

^a BIRMINGHAM WOMEN S HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

^d UNIVERSITY OF MILAN   (Italy)

^e HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE   (Chile)

^f KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Cervicovaginal fluid; Potential fertility; Rovumeter ; Urinary LH peak

Indexed keywords

ESTRONE GLUCURONIDE; LUTEINIZING HORMONE; PREGNANEDIOL;

ADULT; ALGORITHM; ARTICLE; CLINICAL TRIAL; FAMILY PLANNING; FEMALE; FEMALE FERTILITY; HORMONE URINE LEVEL; HUMAN; LUTEAL PHASE; MAJOR CLINICAL STUDY; MENSTRUAL CYCLE; MULTICENTER STUDY; SELF EVALUATION; UTERINE CERVIX; VAGINA; VOLUMETRY;

EID: 0030929523     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/12.8.1826     Document Type: Article

References (28)

1. Anderson, R.A., Eccles, S.M. and Irvine, D.S. (1996) Home ovulation testing in a donor insemination service. Hum. Reprod., 11, 1674-1677.
2. Burger, H.G. (1989) Estradiol: the physiological basis of the fertile period. Int. J. Gynecol Obstet, l (Suppl.), 5-9.
3. Collins, W.P (1989) Biochemical indices of potential fertility. Int. J. Gynecol. Obstet. l (Suppl.), 35-43.
4. Collins, W.P. (1996) Indicators of potential fertility: scientific principles. In Bonnar, J. (ed.), Natural Contraception through Personal Hormone Monitoring. Parthenon Publishing Group, New York, pp. 13-34.
5. Collins, W.P., Collins, P.O., Kilpatrick, M.J. et al. (1979) The measurement of urinary oestrone-3-glucuronide, LH and pregnanediol-3α-glucuronide as indices of ovarian function. Acta Endocrinol., 90, 336-348.
6. Flynn, A.M., McCarthy, N., Docker, M. and Royston, P. (1988a) The temporal relationship between vaginal fluid volumes obtained with the Rovumeter vaginal aspirator and the fertile phase of the cycle. Hum. Reprod., 3, 201-205.
7. Flynn, A.M., Docker, M.F., McCarthy, N. and Royston, P. (1988b) Detection of the fertile phase from changes in cervico-vaginal fluid volume. Int. J. Fertil. 1 (Suppl.), 17-23.
8. Godley, M.J. (1985) Quantitation of vaginal discharge in healthy volunteers. Br. J. Obstet. Gynaecol., 92, 739-742.
9. Hatcher, R.A., Trussell, J., Stewart, F. et al. (1994) The essentials of contraception: effectiveness, safety and personal considerations. In Contraceptive Technology, 16th edn. Irvington Publishers, New York, pp. 107-137.
10. Katz, D.F. (1991) Human cervical mucus: research update. Am. J. Obstet. Gynecol., 165, 1984-1986.
11. Moghissi, K.S. (1979) Vaginal fluid constituents. In Beller, F.K. and Schumacher, G.F.B. (eds), The Biology of the Fluids of the Female Genital Tract. Elsevier-North Holland, NY, USA, pp. 13-23.
12. Moghissi, K.S. (1984) The function of the cervix in human reproduction. Curr. Probl. Obstet. Gynecol., 7, 1-58.
13. Odeblad, E. (1977) Physical properties of cervical mucus. In Mucus in Health and Disease. Adv. Exp. Med. Biol., 89, 217-225.
14. Pratt, D.E., Vignovic, E., Holt, J.A. and Schumacher, G.F. (1992) Correlation of cervicovaginal fluid volume with serum estradiol levels and total follicular volume during human gonadotropin stimulation. J. Assist. Reprod. Genet., 9, 14-18.
15. Robinson, J.N., Lockwood, G.M., Dalton, J.D.E. et al. (1992) A randomised prospective study to assess the effect of the use of home urinary luteinizing hormone detection on the efficiency of donor insemination. Hum. Reprod., 7, 63-65.
16. Royston, P. (1991) Identifying the fertile phase of the human menstrual cycle. Stat. Med., 10, 221-240.
17. Tsibris, J.C.M., Lewis, V., Langenberg, P.W. et al. (1989) Cervical mucus enzymes as markers of the woman's fertile period. Int. J. Gynecol. Obstet. I (Suppl.) 73-82.
18. Usala, J.S. and Schumacher, G.F.B. (1983) Volumetric self-sampling of cervicovaginal fluid: a new approach to ovulation timing. Fertil. Steril., 39, 304-309.
19. Van Koij, R.J., Roelofs, H.J.M., Kathmann, G.A.M. and Kramer, M.F. (1980) Human cervical mucus and its mucus glycoprotein during the menstrual cycle. Fertil. Steril., 34, 226-233.
20. Viergiver, E. and Pommerenke, W.T. (1946) Cyclic variations in the viscosity of cervical mucus and its correlation with amount of secretion and basal temperature. Am. J. Obstet. Gynecol., 51, 192-196.
21. Wagner, G. (1979) Vaginal transudation. In Beller, F.K. and Schumacher, G.F.B. (eds), The Biology of the Fluids of the Female Genital Tract. Elsevier-North Holland, pp. 25-34.
22. Wolf, D.P., Blasco, L., Khan, M.A. and Litt, M. (1978) Human cervical mucus IV. Viscoelasticity and sperm penetrability during the ovulatory menstrual cycle. Fertil. Steril., 30, 163-169.
23. Wolf, D.P., Sokoloski, J.E. and Litt, M. (1980) Composition and function of human cervical mucus. Biochim. Biophys. Acta, 630, 545-558.
24. World Health Organization (198la) A prospective multicentre trial of the ovulation method of natural family planning. I. The teaching phase. Fertil. Steril., 36, 152-158.
25. World Health Organization (1981b) A prospective multicentre trial of the ovulation method of natural family planning. II. The effectiveness phase. Fertil. Steril., 36, 591-598.
26. World Health Organization (1982) The measurement of urinary steroid glucuronides as indices of the fertile period in women. J. Steroid Biochem., 17, 695-702.
27. World Health Organization (1983a) Temporal relationships between indices of the fertile period. Fertil. Steril., 39, 647-655.
28. World Health Organization (1983b) A prospective multicentre trial of the ovulation method of natural family planning. III. Characteristics of the menstrual cycle and of the fertile phase. Fertil. Steril, 40, 773-778.