Increased secretion of gelatinases A and B from the aortas of cholesterol fed rabbits: Relationship to lesion severity

Atherosclerosis

Volumn 130, Issue 1-2, 1997, Pages 61-70

  Zaltsman, Alla B ^a,b   Newby, Andrew C ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b BRISTOL ROYAL INFIRMARY   (United Kingdom)

Author keywords

atherosclerosis; hypercholesterolaemia; macrophages; metalloproteinases; vascular smooth muscle cell

Indexed keywords

METALLOPROTEINASE;

ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; HYPERCHOLESTEROLEMIA; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; RABBIT; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; ARTERIOSCLEROSIS; CHOLESTEROL, DIETARY; COLLAGENASES; CULTURE MEDIA, CONDITIONED; CULTURE TECHNIQUES; CYCLOHEXIMIDE; GELATINASES; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; MUSCLE, SMOOTH, VASCULAR; PROTEIN SYNTHESIS INHIBITORS; RABBITS; RNA, MESSENGER; TUNICA INTIMA;

EID: 0030928829     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(96)06046-7     Document Type: Article

References (24)

1. Birkedal-Hansen H, Moore WGI, Bodden MK, Windsor LJ, Birkedal-Hansen B, De Carlo A, Engler JA. Matrix metalloproteinases: a review. Crit Rev Oral Biol Med 1993;4:197.
2. Newby AC, Fabunmi RP, George SJ, Southgate KM, Banning AP, Thurston VJ, Williams A. Neointimal fibrosis in vascular pathologies: role of growth factors and metalloproteinases in vascular smooth muscle proliferation. Exp Nephrol 1995;3:108.
3. Dollery CM, McEwan JR, Henney AM. Matrix metalloproteinases and cardiovascular disease. Circ Res, 1995;77:863.
4. Southgate KM, Davies M, Booth RFG, Newby AC. Involvement of extracellular matrix degrading metalloproteinases in rabbit aortic smooth muscle cell proliferation. Biochem J 1992;288:93.
5. Pauly RR, Passaniti A, Bilato C, Monticone R, Cheng L, Papadaopoulos N, Gluzband YA, Smith L, Weinstein C, Lakatta EG, Crow MT. Migration of cultured vascular smooth muscle cells through a basement membrane barrier requires type IV collagenase activity and is inhibited by cellular differentiation. Circ Res 1994;75:41.
6. Henney AM, Wakely PR, Davies MJ, Foster K, Hembry R, Murphy G, Humphries S. Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization. Proc Natl Acad Sci USA 1991;88:8154.
7. Galis ZS, Sukhova GK, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994;94:2493.
8. Brown D, Hibbs M, Kearney M, Loushin C, Isner JM. Identification of 92-kDa gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina. Circulation 1995;91:2125.
9. Galis ZS, Sukhova GK, Kranshöfer R, Clark S, Libby P. Macrophage foam cells from experimental atheroma constitutively express matrix-degrading proteases. Proc Natl Acad Sci 1995;92:402.
10. Chappell SP, Lewis MJ, Henderson AH. Effect of lipid-feeding on endothelium-dependent relaxation in rabbit aortic preparations. Cardiovasc Res 1987;21:34.
11. McMurray H, Parrott DP, Bowyer DE. A standardised method of culturing aortic explants, suitable for the study of factors affecting the phenotypic modulation, migration and proliferation of aortic smooth muscle cells. Atherosclerosis 1991;86:227.
12. Southgate KM, Newby AC. Serum-induced proliferation of rabbit aortic smooth muscle cells from the contractile state is inhibited by 8-Br-cAMP but not 8-Br-cGMP. Atherosclerosis 1990;82:113.
13. Kissane JM, Robins E. The fluorimetric measurement of deoxyribonucleic acid in animal tissues with special reference to the central nervous system. J Biol Chem 1958;233: 184.
14. Angelini GD, Bryan AJ, Williams HMJ, Soyombo AA, Williams A, Tovey J, Newby AC. Timecourse of medial and intimal thickening in pig arteriovenous bypass grafts: relationship to endothelial injury and cholesterol accumulation. J Thorac Cardiovasc Surg 1992;103:1093.
15. Tryggvason K, Hoyhtya M, Salo T. Proteolytic degradation of extracellular matrix in tumor invasion. Biochem Biophys Acta 1987;907:191.
16. Anitschkow N, Chalatow S. Uber experimentelle cholesterinsteatose und ihre bendeutung fur die enstehung einiger. Pathologischer prozess. Allg Pathol Anat 1913;24:1.
17. Fabunmi RP, Baker AH, Murray EJ, Booth RFG, Newby AC. Divergent regulation by growth factors and cytokines of 95-kDa and 72-kDa gelatinases and tissue inhibitors of metalloproteinases-1, -2 and -3 in rabbit aortic smooth muscle cells. Biochem J 1996;315:335.
18. Newby AC, Southgate KM, Davies M. Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis. Bas Res Cardiol 1994;89(Suppl. 1):59.
19. Sellers A, Cartwright E, Murphy G, Reynold J. Evidence that latent collagenases are enzyme inhibitor complexes. Biochem J 1977;163:303.
20. Li Z, Li L, Zielke R, Cheng L, Xiao R, Crow MT, Stetler-Stephenson G, Froehlich J, Lakatta EG. Increased expression of 72 kd type IV collagenase in human aortic atherosclerotic lesions. Am J Pathol 1996;148:148.
21. Zempo N, Kenagy RD, Au T, Bendeck M, Clowes MM, Reidy MA, Clowes AW. Matrix metalloproteinases of vascular wall cells are increased in balloon-injured rat carotid artery. J Vasc Surg 1994;20:209.
22. Bendeck MP, Zempo N, Clowes AW, Gelardy RE, Reidy MA. Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat. Circ Res 1994;75:539.
23. Zempo N, Koyama N, Kenagy RD, Lea HJ, Clowes AW. Regulation of vascular smooth muscle cell migration and proliferation in vitro and in injured rat arteries by a synthetic matrix metalloproteinases inhibitor. Arterioscler Thromb Vasc Biol 1996;16:28.
24. Fabumni RP, Bond M, Newby AC. Divergent regulation of MMPs-1, -3 and -9 by growth factors and cytokines in rabbit smooth muscle cells and dermal fibroblasts. J Vasc Res 1996;33:S1,26.