A convenient synthesis of 15N-labeled diethylenetriamine [(15N)dien] and ethylenediamine [(15N)En]

Synthesis

Volumn , Issue 4, 1997, Pages 410-412

  Zang, Erle ^a   Sadler, Peter J ^a,b  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

(15N) labeled ligands; (15N)diethylenetriamine; (15N)ethylenediamine; polyamine ligands; trityl group

Indexed keywords

DIETHYLENETRIAMINE; ETHYLENEDIAMINE; NITROGEN 15; POLYAMINE;

ARTICLE; DRUG SYNTHESIS; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; ISOTOPE LABELING; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

EID: 0030928420     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1997-1208     Document Type: Article

References (11)

1. Barnham, K. J.; Djuran, M. I.; Murdoch, P. del S.; Sadler, P. J. J. Chem. Soc., Chem. Commun. 1994, 721.
2. Lempers, E. L. M.; Bloemink, M. J.; Reedijk, J. Inorg. Chem. 1991, 30, 201.
3. Brabec, V.; Reedijk, J.; Leng, M. Biochemistry 1992, 31, 12397.
4. Reedijk, J. Inorg. Chim. Acta 1992, 198-200, 873.
5. Berners-Price, S. J.; Frenkiel, T. A.; Ranford, J. D.; Sadler, P. J. J. Chem. Soc., Dalton Trans 1992, 2137.
6. Mann, F. G. J. Chem. Soc. 1934, 461.
7. Unpublished results.
8. Zervas, L.; Theodoropoulos, D. M. J. Am. Chem. Soc. 1956, 78, 1359.
9. 15N 12.11.
10. Perrin, D. D.; Armarego, W. L. F. Purification of Laboratory Chemicals, 3rd ed.; Pergamon; Oxford, 1988.
11. The IR spectrum is consistent with that from commercial unlabelled product as the hydrochloride salt.