Studies on amidated pectins as potential carriers in colonic drug delivery

Journal of Pharmacy and Pharmacology

Volumn 49, Issue 6, 1997, Pages 622-625

  Wakerly, Zoë ^a   Fell, John ^a   Attwood, David ^a   Parkins, David ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG CARRIER; PARACETAMOL; PECTIN;

AMIDATION; ARTICLE; COLON; CONTROLLED STUDY; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG RELEASE; MATRIX TABLET; VISCOSITY;

EID: 0030928270     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1997.tb06856.x     Document Type: Article

References (6)

1. Ashford, M., Fell, J., Attwood, D., Sharma, H., Woodhead, P. (1993) An evaluation of pectin as a carrier for drug targeting to the colon. J. Contr. Rel. 26: 213-200
2. Ashford, M., Fell, J., Attwood, D., Sharma, H., Woodhead, P. (1994) Studies on pectin formulations for colonic drug delivery. J. Contr. Rel. 30: 225-232
3. Grant, G. T., Morris, E. R., Rees, D. A., Smith, P. J. C., Thom, D. (1973) Biological interactions between polysaccharides and divalent cations. The egg box model. FEBS Lett. 32: 195-198
4. Rubinstein, A., Radai, R., Ezra, M., Pathak, S., Rokem, J. S. (1993) Invitro evaluation of calcium pectinate: a potential colon-specific drug-delivery carrier. Pharm. Res. 10: 258-263
5. Talukdar, M. M., Vinekier, I., Moldenaers, P., Kinget, R. (1996) Rheological characterization of xanthan gum and hydroxypropylmethyl cellulose with respect to controlled-release drug delivery. J. Pharm. Sci. 85: 537-540
6. Wakerly, Z. (1995) An Investigation into Citrus Pectins for Colonic Drug Delivery. PhD Thesis. University of Manchester