Extracellular GTP causes membrane-potential oscillations through the parallel activation of mg2+ and na+ currents in Paramecium tetraurelia

Journal of Membrane Biology

Volumn 157, Issue 2, 1997, Pages 159-167

  Clark, K D ^a   Hennessey, T M ^b   Nelson, D L ^a   Preston, R R ^c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Ca2+ conductance; Conductance; Electrophysiology; GTP; Mg2+; Na+ conductance; Paramecium; Purinergic

Indexed keywords

GUANOSINE TRIPHOSPHATE;

ARTICLE; CALCIUM CONDUCTANCE; CELL MEMBRANE POTENTIAL; ION CONDUCTANCE; ION CURRENT; MEMBRANE DEPOLARIZATION; NONHUMAN; OSCILLATION; PARAMECIUM TETRAURELIA; SODIUM CONDUCTANCE; VOLTAGE CLAMP;

ANIMALS; CALCIUM; CALCIUM CHANNELS; GUANOSINE TRIPHOSPHATE; MAGNESIUM; MEMBRANE POTENTIALS; PARAMECIUM TETRAURELIA; PATCH-CLAMP TECHNIQUES; RECEPTORS, PURINERGIC; SODIUM;

PARAMECIUM; PARAMECIUM TETRAURELIA;

EID: 0030927884     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002329900225     Document Type: Article

References (31)

1. Clark K.D., Hennessey, T.M., Nelson, D.L. 1993. External GTP alters the motility and elicits an oscillating membrane depolarization in Paramecium tetraurelia. Proc. Natl. Acad. Sci. USA 90:3782-3786
2. Dunlap, K. 1977. Localization of calcium channels in Paramecium caudatum. J. Physiol. (London) 271:119-133
3. Erxleben, C., Plattner, H. 1994. Ca release from subplasmalemmal stores as a primary event during exocytosis in Paramecium cells. J. Cell Biol. 127:935-945
4. Francis, J.T., Hennessey, T.M. 1995. Chemorepellents in Paramecium and Tetrahymena. J. Euk. Microbiol. 42:78-83
5. Gordon, J.L. 1986. Extracellular ATP: effects, sources and fate. Biochem. J. 233:309-319
6. Gustin, M., Hennessey, T.M. 1988. Neomycin inhibits the calcium current of Paramecium. Biochim. Biophys. Acta 940:99-104
7. ++ conductance. J. Membrane Biol. 148:13-25
8. Hennessey, T.M., Kung, C. 1984. An anticalmodulin drug, W-7, inhibits the voltage-dependent calcium current in Paramecium caudatum. J. Exp. Biol. 110:169-181
9. Hinrichsen, R.E., Saimi, Y. 1984. A mutation that alters the properties of the calcium channel in Paramecium tetraurelia. J. Physiol. 351:397-410
10. Kink, J.A., Maley, M., Preston, R.R., Ling, K.-Y., Wallen-Friedman, M.A., Saimi, Y. Kung, C. 1990. Mutations in Paramecium calmodulin indicate functional differences between the C-terminal and N-terminal lobes in vivo. Cell 62:165-174
11. Kung, C. 1971. Genic mutants with altered system of excitation in Paramecium tetraurelia. II. Mutagenesis. screening and genetic analysis of the mutants. Genetics 69:29-45
12. Kung, C., Saimi, Y. 1982. The physiological basis of taxes in Paramecium. Annu. Rev. Physiol. 44:519-534
13. Länge, S., Klauke, N., Plattner, H. 1995. Subplasmalemmal Ca stores of probable relevance for exocytosis in Paramecium. Alveolar sacs share some but not all characteristics with sarcoplasmic reticulum. Cell Calcium 17:335-344
14. Lefort-Tran, M., Aufderheide, K., Pouphile, M., Rossignol, M., Beisson, J. 1981. Control of exocytotic processes: cytological and physiological studies of trichocyst mutants in Paramecium tetraurelia. J. Cell Biol. 88:301-311
15. Machemer, H. 1988. Electrophysiology. In: Paramecium. H.-D. Goertz, editor, pp. 186-215. Springer-Verlag, Berlin
16. Naitoh, Y., Eckert, R. 1969. Ionic mechanisms controlling behavioral responses of Paramecium to mechanical stimulation. Science 164:963-965
17. Naitoh, Y., Kaneko, H. 1972. Reactivated Triton-extracted models of Paramecium: modification of ciliary movement by calcium ions. Science 176:523-524
18. Oertel, D., Schein, S.J., Kung, C. 1977. Separation of membrane currents using a Paramecium mutant. Nature 268:120-124
19. Ogura, A., Takahashi, K. 1976. Artificial deciliation causes loss of calcium-dependent responses in Paramecium. Nature 264:170-172
20. Preston, R.R. 1990. A magnesium current in Paramecium. Science 250:285-288
21. Preston, R.R., Kung, C. 1994. Isolation and characterization of Paramecium mutants defective in their response to magnesium. Genetics 137:759-769
22. + currents activated upon hyperpolarization of Paramecium tetraurelia. J. Membrane Biol. 115:41-51
23. Preston, R.R., Saimi, Y., Kung, C. 1992. Calcium current activated upon hyperpolarization of Paramecium tetraurelia. J. Gen. Physiol. 100:233-251
24. Preston, R.R., Usherwood, P.N.R. 1988. L-Glutamate-induced membrane hyperpolarization and behavioural responses in Paramecium tetraurelia. J. Comp. Physiol. 164A:75-82
25. + current shuts off one type of excitation in Paramecium. Proc. Natl. Acad. Sci. USA 80:5112-5116
26. Saimi, Y., Kung, C. 1980. A Ca-induced Na-current in Paramecium. J. Exp. Biol. 88:305-325
27. Saimi, Y., Ling, K.-Y. 1990. Calmodulin activation of calcium-dependent sodium channels in excised membrane patches of Paramecium. Science 249:1441-1444
28. Stelly, N., Mauger, J.-P., Claret, M., Adoutte, A. 1991. Cortical alveoli of Paramecium: a vast submembranous calcium storage compartment. J. Cell Biol. 113:103-112
29. Tsien, R.W., Tsien, R.Y. 1990. Calcium channels, stores, and oscillations. Annu. Rev. Cell. Biol. 6:715-760
30. 2+]. Biophys. J. 56:1255-1258
31. 2+. J. Membrane Biol. 127:185-193