Identification of a cis-acting element within the herpesvirus saimiri ORF 6 promoter that is responsive to the HVS.R transactivator

Journal of General Virology

Volumn 78, Issue 6, 1997, Pages 1411-1415

  Whitehouse, Adrian ^a   Stevenson, Alex J ^a   Cooper, Matthew ^a   Meredith, David M ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT;

ARTICLE; HERPES VIRUS SAIMIRI; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; TRANSACTIVATION; TRANSCRIPTION INITIATION;

EID: 0030927759     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-78-6-1411     Document Type: Article

References (19)

1. Albrecht, J. C. & Fleckenstein, B. (1990). Structural organization of the conserved gene block of herpesvirus saimiri coding for DNA polymerase, glycoprotein B, and major DNA binding protein. Virology 174, 533-542.
2. Albrecht, J. C., Nicholas, J., Biller, D., Cameron, K. R., Biesinger, B., Newman, C., Wittman, S., Craxton, M. A., Coleman, H., Fleckenstein, B. & Honess, R. W. (1992). Primary structure of the herpesvirus saimiri genome. Journal of Virology 66, 5047-5058.
3. Andrews, N. C. & Faller, D. V. (1991). A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Research 19, 2499.
4. Bublot, M., Manet, E., Lequarre, A. S., Albrecht, J. C., Nicholas, J., Fleckenstein, B., Pastoret, P. P. & Thiry, E. (1992). Genetic relationships between bovine herpesvirus 4 and the gamma-herpesviruses Epstein-Barr and herpesvirus saimiri. Virology 190, 654-665.
5. Buisson, M., Manet, E., Trescol-Biemont, M.-C., Gruffat, H., Durand, B. & Sergeant, A. (1989). The Epstein-Barr virus (EBV) early protein EB2 is a post transcriptional activator expressed under the control of EBV transcription factors EB1 and R. Journal of Virology 63, 5276-5284.
6. Fleckenstein, B. & Desrosiers, R. C. (1982). Herpesvirus saimiri and herpesvirus ateles. In The Herpesviruses, vol. 1, pp. 253-332. Edited by B. Roizman. New York: Plenum Press.
7. Furnari, F. B., Zacny, V., Quinlivan, E. B., Kenney, S. & Pagano, J. S. (1994). RAZ, an Epstein-Barr virus transdominant repressor that modulates the viral reactivation mechanism. Journal of Virology 68, 1827-1836.
8. Gompels, U. A., Craxton, M. A. & Honess, R. W. (1988a). Conservation of gene organization in the lymphotropic herpesvirus saimiri. Journal of Virology 62, 757-767.
9. Gompels, U. A., Craxton, M. A. & Honess, R. W. (1988b). Conservation of glycoprotein H (gH) in herpesvirus: nucleotide sequence of the gH gene from herpesvirus saimiri. Journal of General Virology 69, 2819-2829.
10. Gorman, C. M., Moffat, L. F. & Howard, B. H. (1982). Recombinant genomes which express chloramphenicol acetyl-transferase in mammalian cells. Molecular and Cellular Biology 2, 1044-1051.
11. Gruffat, H. & Sergeant, A. (1994). Characterization of the DNA-binding site repertoire for the Epstein - Barr virus transcription factor R. Nucleic Acids Research 22, 1172-1178.
12. Gruffat, H., Manet, E., Rigolet, A. & Sergeant, A. (1990). The enhancer factor R of Epstein - Barr virus (EBV) is a sequence specific DNA binding protein. Nucleic Acids Research 18, 6835-6843.
13. Gruffat, H., Duran, N., Buisson, M., Wild, F., Buckland, R. & Sergeant, A. (1992). Characterization of an R-binding site mediating the R-induced activation of the Epstein - Barr virus BMLF1 promoter. Journal of Virology 66, 46-52.
14. Kenney S., Holley-Guthrie, E. A., Mar, E.-C. & Smith, M. (1989). The Epstein - Barr virus BMLF1 promoter contains an enhancer element that is responsive to the BZLF1 and BRLF1 transactivators. Journal of Virology 63, 3878-3883.
15. Knust, E., Schirm, S., Dietrich, W., Bodemer, W., Kolb, E. & Fleckenstein, B. (1983). Cloning of the herpesvirus saimiri DNA fragments representing the entire L-region of the genome. Gene 25, 281-289.
16. Nicholas, J., Cameron, K. R., Coleman, H., Newman, C. & Honess, R. W. (1992). Analysis of nucleotide sequence of the rightmost 43 kbp of herpesvirus saimiri (HVS) L-DNA: general conservation of genetic organization between HVS and Epstein - Barr virus. Virology 188, 296-310.
17. Nicholas, J., Coles, L. S., Newman, C. & Honess, R. W. (1991). Regulation of the herpesvirus saimiri (HVS) delayed-early 110-kilodalton promoter by HVS immediate-early gene products and a homolog of the Epstein - Barr virus R transactivator. Journal of Virology 65, 2457-2466.
18. Rooney, C. M., Rowe, D. T., Ragot, T. & Farrell, P. J. (1989). The spliced BZLF1 gene of Epstein - Barr virus (EBV) transactivates an early EBV promoter and induces the virus production cycle. Journal of Virology 63, 3109-3116.
19. Whitehouse, A., Carr, I., Griffiths, J. C. & Meredith, D. M. (1997). The herpesvirus saimiri ORF 50 gene, encoding a major transcriptional activator homologous to the Epstein - Barr Virus R protein, is transcribed from two distinct promoters of different temporal phases. Journal of Virology 71, 2550-2554.