Effects of chronic losartan treatment on vascular reactivity in normotensive rats

Journal of Hypertension

Volumn 15, Issue 5, 1997, Pages 523-529

  Dowell, Fiona J ^a   Benessiano, Joëlle ^a   Poitevin, Pierre ^a   Levy, Bernard I ^a   Henrion, Daniel ^a,b  

^a HÔPITAL LARIBOISIÈRE   (France)

^b INSERM   (France)

Author keywords

Angiotensin II; Aorta; AT1 receptors; Mesenteric artery; Phenylephrine; Potentiation

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; LOSARTAN; LOSARTAN POTASSIUM; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERY CONSTRICTION; ARTERY RESISTANCE; ARTERY WALL; ARTICLE; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; CAROTID ARTERY; CONTROLLED STUDY; FORCE; MALE; MESENTERIC ARTERY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; THORACIC AORTA;

EID: 0030927552     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199715050-00008     Document Type: Article

References (37)

1. Bumpus FM, Catt KJ, Chiu AT, De Gasparo M, Goodfriend T, Husain A, et al.: Nomenclature for angiotensin receptors. A report of the Nomenclature Committee of the Council for High Blood Pressure Research. Hypertension 1991, 17:720-721.
2. Soltis EE, Jewel AL, Bwoskin LP, Cassis LA: Acute and chronic effect of losartan (DuP753) on blood pressure and vascular reactivity in normotensive rats. Clin Exp Hypertens 1993, 62:889-897.
3. Soltis EE: Alterations in vascular structure and function after short term losartan treatment in spontaneously hypertensive rats. J Pharmacol Exp Ther 1993, 266:642-646.
4. Chui AT, McCall DE, Price WA, Wong PC, Carini DJ, Duncia JV, et al.: Non-peptide angiotensin receptor antagonists VII: cellular and biochemical pharmacology of DuP753, an orally active antihypertensive agent. J Pharmacol Exp Ther 1990, 252:711-718.
5. Wong PC, Price WA, Chui AT, Duncia JV, Carini DJ, Wexler RR, et al.: Nonpeptide angiotensin II receptor antagonists: X. Hypotensive actions of DuP753, an angiotensin II antagonist in spontaneously hypertensive rats. Hypertension 1990, 15:459-468.
6. Wong PC, Price WA, Chui AT, Duncia JV, Carini DJ, Johnson AL, et al.: Nonpeptide angiotensin II receptor antagonist: studies with EXP9270 and Dup753. Hypertension 1990, 15:823-834.
7. Inamura A, MacKenzie HS, Ploth DW: Effect of chronic administration of losartan on renal function and development of hypertension in 2-kidney, 1-clip hypertensive rats. Clin Res 1992, 40:315-322.
8. Sleckelings U, Obermuller N, Bottari SP, Qadri F, Veltmar A, Unger T: Brain angiotensin: receptors, actions and possible role in hypertension. Pharmacol Toxicol 1992, 70 (suppl II):S23-S27.
9. Day MD. Moore AF: Interaction of angiotensin II with noradrenaline and other spasmogens on rabbit isolated aortic strips. Arch Int Pharmacodyn Ther 1976, 219:29-35.
10. Duckles SP: Angiotensin 1I potentiates responses of the rabbit basilar artery to adrenergic nerve stimulation. Life Sci 1981, 28:40-47.
11. Weber MA, Purdy RE, Stupecky GL, Prins BA: Augmentation of sympathomimetic arterial contraction by angiotensin II: a novel mechanism. J Vasc Med Biol 1989, 1:7-15.
12. Vanhoutte PM, Verbeuren TJ, Webb RC: Local modulation of adrenergic neuroeffector interaction in the blood vessel wall. Physiol Rev 1981, 61:151-159.
13. Laher I, Thompson LP, Gagne L: Protein kinase C as a modulator of response amplification in vascular smooth muscle. Blood Vessels 1990, 27:333-340.
14. 2+ influx: role of protein kinase C. J Pharmacol Exp Ther 1992, 261:835-842.
15. Henrion D, Laher I, Laporte R, Bevan JA: Further evidence from an elastic artery that angiotensin II amplifies noradrenaline-induced contraction through activation of protein kinase C. Eur J Pharmacol 1992, 224:13-20.
16. Qiu HY, Henrion D, Levy BI: Endogenous angiotensin II enhances phenylephrine-induced tone in hypertensive rats. Hypertension 1994, 24:317-321.
17. Dowell FJ, Henrion D, Benessiano J, Poitevin, Levy BI: Chronic infusion of low dose angiotensin II potentiates the in vitro adrenergic response. J Hypertens 1996, 14:177-182.
18. Soltis EE, Jewel AL, Bwoskin LP, Cassis LA: Acute and chronic effects of losartan (DuP753) on blood pressure and vascular reactivity in normotensive rats. Clin Exp Hypertens 1993, 15:171-184.
19. Chansel D, Badre L, Czekalski S, Vandermeersch S, Cambar J, Ardaillou R: Intrinsic properties of the non-peptide angiotensin II antagonist losartan in glomeruli and mesangial cells at high concentrations. J Pharmacol Exp Ther 1993, 265:1534-1543.
20. 3 and nicotine in rats. J Pharmacol Exp Ther 1992, 260:1-8.
21. Mulvany MJ, Halpern W: Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circulation 1977, 41:19-26.
22. Dunn WR, Wellman GC Bevan JA: Enhanced resistance artery sensitivity to agonists under isobaric compared with isometric conditions. Am J Physiol 1994, 266:H147-H155.
23. Henrion D, Laher I: Potentiation of norepinephrine-induced contractions by endothelin-1 in the rabbit aorta. Hypertension 1993, 22:78-83.
24. Simon D, Romestand B, Huang H, Badouaille G, Fehrentz J-A, Pau B, et al.: Direct, simplified and sensitive assay of angiotensin II in plasma extracts performed with a high-affinity monoclonal antibody. Clin Chem 1992, 38:1963-1967.
25. Michaelis L. Menten T: Die Kinetic der Invertinwirkung. Biochem Z 1913, 49:333-342.
26. Bayliss C: Renal response to acute angiotensin II inhibition and administered angiotensin II in the aging, concious, chronically catheterised rat. Am J Kidney Dis 1993, 22:842-850.
27. Chansel D, Bizet T, Vandermeersch S, Pham P, Levy BI, Ardaillou R: Differential regulation of angiotensin II and losartan binding sites in glomeruli and mesangial cells. Am J Physiol 1994, 266:F384-F393.
28. Wong PC, Price WA, Chui AT, Duncia JV, Carini DJ, Johnson AL, et al.: Nonpeptide angiotensin II receptor antagonists: VIII. Characterisation of functional antagonism displayed by DuP753, an orally active antihypertensive agent J Pharmacol Exp Ther 1990, 252:719-725.
29. Wong PC, Price WA, Chui AT, Duncia JV, Carini DJ, Johnson AL, et al.: In vivo pharmacology of DuP753. Am J Hypertens 1991, 4 (suppl 1): 288S-298S.
30. Goldberg MR, Tanaka W, Barchowsky A, Bradstreet TE, McCrea J, Lo MW, et al.: Effects of losartan on blood pressure, plasma renin activity and angiotensin II in volunteers. Hypertension 1993, 21:704-713.
31. Munafo A, Christen Y, Nussberger J, Shum LY, Borland RM, Lee RJ, et al.: Drug concentration response relationships in normal volunteers after oral administration of losartan, an angiotensin II receptor antagonist. Clin Pharmacol Ther 1992, 51:513-521.
32. De Graaf GL, Pals DT, Couch SJ, Lawson JA: Hormonal and cardiovascular effects of losartan (DUP753), an angiotensin receptor antagonist, in non-human primates. J Pharmacol Exp Ther 1993, 294:6-10.
33. Fitzpatrick MA, Rademaker MT, Charles CJ, Yandle T, Espiner EA, Ikram H: Angiotensin II receptor antagonism in ovine heart failure: acute hemodynamic, hormonal and renal effects. Am J Physiol 1992, 263:H250-H256.
34. Ullian ME, Linas SE: Role of receptor recycling in the regulation of angiotensin II surface receptor number and angiotensin II uptake in rat vascular smooth muscle cells. J Clin Invest 1989, 84:840-846.
35. 2-adrenoreceptors in isolated perfused kidneys of spontaneously hypertensive rats. Cardiovasc Res 1995, 30:587-865.
36. Mombouli JV, Vanhoutte PM: Heterogeneity of endothelium dependent vasodilator effects of angiotensin converting enzyme inhibitors. J Cardiovasc Pharmacol 1992, 20 (suppl 9):S74-S83.
37. Ling W, Wiemer G, Göhlke P, Unger T, Schölkens BA: Contribution of kinins to the cardiovascular effect of angiotensin converting enzyme inhibitors. Pharmacol Rev 1995, 47:25-49.